Shenyang Agricultural University 3 articles published in JoVE Immunology and Infection A Catheter-Related Candida albicans Infection Model in Mouse Chen Yang1, Fei Mo2, Jiaxue Zhang1, Peipei Zhang1, Qingqing Li1, Jiye Zhang1 1 We establish a mouse model of C.albicans-associated catheter-related infection (CRI), in which biofilm forms on the catheter, and the interaction between C.albicans and host correlates well with the clinical CRI. This model helps screen therapies for C.albicans biofilm-associated CRI, laying a foundation for clinical transformation. Immunology and Infection A Periprosthetic Joint Candida albicans Infection Model in Mouse Chen Yang1, Jiaxue Zhang1, Fei Mo2, Peipei Zhang1, Qingqing Li1, Jiye Zhang1 1 Periprosthetic joint infection (PJI) caused by dangerous pathogens is common in clinical orthopedics. Existing animal models cannot accurately simulate the actual situation of PJI. Here, we established a Candida albicans biofilm-associated PJI mouse model to research and develop new therapeutics for PJI. Biology RNA Interference in the Egg Parasitoid, Trichogramma dendrolimi Matsumura Long-xi Zhang1, Qian-jin Dong1, Shuai Yang1, Wu-nan Che1, Li-sheng Zhang2, Jin-cheng Zhou1,2, Hui Dong1 1College of Plant Protection, Shenyang Agricultural University, 2State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences The manipulation of RNA interference (RNAi) presents a formidable challenge in many parasitoid species with diminutive size, such as Trichogramma wasps. This study delineated an efficient RNAi method in Trichogramma denrolimi. The present methodology provides a robust model for investigating gene regulation in Trichogramma wasps.
