University of Torino, San Luigi Gonzaga Hospital 1 article published in JoVE Medicine Ultrasound-guided Botulinum Toxin-A Injections: A Method of Treating Sialorrhea Pierangelo Barbero1, Marco Busso2, Carlo Alberto Artusi1, Stefania De Mercanti1, Marco Tinivella3, Andrea Veltri2, Luca Durelli1, Marinella Clerico1 1Clinical and Biological Sciences Department, Neurology Unit, University of Torino, San Luigi Gonzaga Hospital, 2Oncology Department, Radiology Unit, University of Torino, San Luigi Gonzaga Hospital, 3Clinical and Biological Sciences Department, Dietologic and Nutrition Unit, University of Torino, San Luigi Gonzaga Hospital Botulinum toxin is injected into the salivary glands for the treatment of sialorrhea. The ultrasound-guided botulinum toxin injection in both the parotid and submandibular glands demonstrates a sustained efficacy and the absence of serious side effects.