Temerty Centre for Therapeutic Brain Intervention at the Centre for Addiction and Mental Health 1 article published in JoVE Neuroscience Combined Transcranial Magnetic Stimulation and Electroencephalography of the Dorsolateral Prefrontal Cortex Pantelis Lioumis1, Reza Zomorrodi1, Itay Hadas1, Zafiris J. Daskalakis1,2, Daniel M. Blumberger1,2 1Temerty Centre for Therapeutic Brain Intervention at the Centre for Addiction and Mental Health, 2Department of Psychiatry and Institute of Medical Science, Faculty of Medicine, University of Toronto The protocol presented here is for TMS-EEG studies utilizing intracortical excitability test-retest design paradigms. The intent of the protocol is to produce reliable and reproducible cortical excitability measures for assessing neurophysiological functioning related to therapeutic interventions in the treatment of neuropsychiatric diseases such as major depression.