ATR Biotech 1 article published in JoVE Bioengineering Operation of a Benchtop Bioreactor Kristina M. Obom1, Andrew Magno2, Patrick J. Cummings1 1Center for Biotechnology Education, Krieger School of Arts and Sciences, Johns Hopkins University, 2ATR Biotech Fermentors are used to increase culture yield and productivity of bioengineered cells. After screening multiple microbial or animal cell culture candidates in shake flasks, the next logical step is to increase the selected culture’s biomass with the fermentor. This video demonstrates the setup and operation of a typical benchtop bioreactor system.