JoVE Journal
Behavior
Behavior
A subscription to JoVE is required to view this content. Sign in or start your free trial.
Chapters
Summary
The unpredictable chronic mild stress (UCMS) protocol is a validated method for studying behavioral and physiological changes associated with chronic stress and depressive symptoms. Eight weeks of imposition of the UCMS protocol induces behavioral changes and poor health outcomes in rodents of either gender.