In JoVE (1)
Articles by Ahmed Hassan in JoVE
De Voxels ao Conhecimento: Um Guia Prático para a segmentação do Complexo Microscopia Eletrônica 3D-Data Wen-Ting Tsai1, Ahmed Hassan1, Purbasha Sarkar2, Joaquin Correa1,3, Zoltan Metlagel1, Danielle M. Jorgens1, Manfred Auer1,2 1Life Sciences Division, Lawrence Berkeley National Laboratory, 2Joint Bioenergy Institute, Physical Biosciences Division, Lawrence Berkeley National Laboratory, 3National Energy Research Scientific Computing Center, Lawrence Berkeley National Laboratory O gargalo para microscopia eletrônica 3D celular é a extração de características (segmentação) em alta complexidade mapas de densidade 3D. Temos desenvolvido um conjunto de critérios, que fornece orientação sobre qual abordagem de segmentação (manual, semi-automática ou automática) é o mais adequado para os diferentes tipos de dados, proporcionando, assim, um ponto de partida para a segmentação eficaz.
Other articles by Ahmed Hassan on PubMed
Are Sudanese Community Pharmacists Capable to Prescribe and Demonstrate Asthma Inhaler Devices to Patrons? A Mystery Patient Study Pharmacy Practice. Apr, 2012 | Pubmed ID: 24155826 Although community pharmacists have become more involved in the care of asthma patients, several studies have assessed pharmacists''ability to illustrate appropriately inhalation technique of different asthma devices. Many studies addressed inappropriate use of asthma devices by patients and pharmacists, in addition to its clinical, humanistic and economic burden.
Crystal Structure Elucidation and Anticancer Studies of (-)-pseudosemiglabrin: a Flavanone Isolated from the Aerial Parts of Tephrosia Apollinea PloS One. 2014 | Pubmed ID: 24608571 Tephrosia apollinea is a perennial shrublet widely distributed in Africa and is known to have medicinal properties. The current study describes the bio-assay (cytotoxicity) guided isolation of (-)-pseudosemiglabrin from the aerial parts of T. apollinea. The structural and stereochemical features have been described using spectral and x-ray crystallographic techniques. The cytotoxicity of isolated compound was evaluated against nine cancer cell lines. In addition, human fibroblast was used as a model cell line for normal cells. The results showed that (-)-pseudosemiglabrin exhibited dose-dependent antiproliferative effect on most of the tested cancer cell lines. Selectively, the compound showed significant inhibitory effect on the proliferation of leukemia, prostate and breast cancer cell lines. Further studies revealed that, the compound exhibited proapoptotic phenomenon of cytotoxicity. Interestingly, the compound did not display toxicity against the normal human fibroblast. It can be concluded that (-)-pseudosemiglabrin is worthy for further investigation as a potential chemotherapeutic agent.