Akira Miyazaki

Publications

• Thrombolytic Therapy for Acute Ischemic Stroke: Past and Future
  Current Pharmaceutical Design. 2019  |   Pubmed ID: 30892155
• Endothelial Calpain Systems Orchestrate Myofibroblast Differentiation During Wound Healing
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Feb, 2019  |   Pubmed ID: 30199285
• Impact of Dysfunctional Protein Catabolism on Macrophage Cholesterol Handling
  Current Medicinal Chemistry. 2019  |   Pubmed ID: 29589525
• Expression of Steroidogenic Enzymes and Metabolism of Steroids in COS-7 Cells Known As Non-steroidogenic Cells
  Scientific Reports. 02, 2018  |   Pubmed ID: 29391479
• The Impact of Stromal Hic-5 on the Tumorigenesis of Colorectal Cancer Through Lysyl Oxidase Induction and Stromal Remodeling
  Oncogene. 03, 2018  |   Pubmed ID: 29242607
• Dysregulation of Calpain Proteolytic Systems Underlies Degenerative Vascular Disorders
  Journal of Atherosclerosis and Thrombosis. Jan, 2018  |   Pubmed ID: 28819082
• Emerging Roles of Calpain Proteolytic Systems in Macrophage Cholesterol Handling
  Cellular and Molecular Life Sciences : CMLS. 08, 2017  |   Pubmed ID: 28432377
• Differential Lactate and Cholesterol Synthetic Activities in XY and XX Sertoli Cells
  Scientific Reports. 02, 2017  |   Pubmed ID: 28150810
• Potential Contribution of the Hepcidin-macrophage Axis to Plaque Vulnerability in Acute Myocardial Infarction in Human
  International Journal of Cardiology. Jan, 2017  |   Pubmed ID: 27855289
• Functional Heterogeneity of Nadph Oxidases in Atherosclerotic and Aneurysmal Diseases
  Journal of Atherosclerosis and Thrombosis. Jan, 2017  |   Pubmed ID: 27476665
• Priming with Erythropoietin Enhances Cell Survival and Angiogenic Effect of Mesenchymal Stem Cell Implantation in Rat Limb Ischemia
  Regenerative Therapy. Jun, 2016  |   Pubmed ID: 31245482
• Calpain-6 Confers Atherogenicity to Macrophages by Dysregulating Pre-mRNA Splicing
  The Journal of Clinical Investigation. 09, 2016  |   Pubmed ID: 27525442
• Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) Is Involved in Adult Mouse Hippocampal Neurogenesis After Stroke
  Journal of Molecular Neuroscience : MN. Jun, 2016  |   Pubmed ID: 26910758
• Fibroblast Growth Factor-23 Induces Cellular Senescence in Human Mesenchymal Stem Cells from Skeletal Muscle
  Biochemical and Biophysical Research Communications. Feb, 2016  |   Pubmed ID: 26797283
• Hic-5 Deficiency Attenuates the Activation of Hepatic Stellate Cells and Liver Fibrosis Through Upregulation of Smad7 in Mice
  Journal of Hepatology. Jan, 2016  |   Pubmed ID: 26334580
• Hydrogen Peroxide-inducible Clone-5 Regulates Mesangial Cell Proliferation in Proliferative Glomerulonephritis in Mice
  PloS One. 2015  |   Pubmed ID: 25835392
• Calpastatin Counteracts Pathological Angiogenesis by Inhibiting Suppressor of Cytokine Signaling 3 Degradation in Vascular Endothelial Cells
  Circulation Research. Mar, 2015  |   Pubmed ID: 25648699
• Role of Hic-5 in the Formation of Microvilli-like Structures and the Monocyte-endothelial Interaction That Accelerates Atherosclerosis
  Cardiovascular Research. Mar, 2015  |   Pubmed ID: 25587044
• NADPH Oxidase Deficiency Exacerbates Angiotensin II-induced Abdominal Aortic Aneurysms in Mice
  Arteriosclerosis, Thrombosis, and Vascular Biology. Nov, 2014  |   Pubmed ID: 25189573
• Identification of Hic-5 As a Novel Scaffold for the MKK4/p54 JNK Pathway in the Development of Abdominal Aortic Aneurysms
  Journal of the American Heart Association. May, 2014  |   Pubmed ID: 24811612
• Time Course-changes in Phosphatidylcholine Profile During Oxidative Modification of Low-density Lipoprotein
  Lipids in Health and Disease. Mar, 2014  |   Pubmed ID: 24625108
• Calpain and Atherosclerosis
  Journal of Atherosclerosis and Thrombosis. 2013  |   Pubmed ID: 23171729
• Salusin-β Accelerates Inflammatory Responses in Vascular Endothelial Cells Via NF-κB Signaling in LDL Receptor-deficient Mice in Vivo and HUVECs in Vitro
  American Journal of Physiology. Heart and Circulatory Physiology. Jul, 2012  |   Pubmed ID: 22561298
• Coexpression of CCR6 and CD146 (MCAM) is a Marker of Effector Memory T-helper 17 Cells
  The Journal of Dermatology. Oct, 2012  |   Pubmed ID: 22486269
• Hydrogen Peroxide-inducible Clone 5 (Hic-5) As a Potential Therapeutic Target for Vascular and Other Disorders
  Journal of Atherosclerosis and Thrombosis. 2012  |   Pubmed ID: 22472216
• Effects of PKF275-055, a Dipeptidyl Peptidase-4 Inhibitor, on the Development of Atherosclerotic Lesions in Apolipoprotein E-null Mice
  Metabolism: Clinical and Experimental. Jul, 2012  |   Pubmed ID: 22225957
• M-Calpain Induction in Vascular Endothelial Cells on Human and Mouse Atheromas and Its Roles in VE-cadherin Disorganization and Atherosclerosis
  Circulation. Dec, 2011  |   Pubmed ID: 22064597
• Purification of Recombinant Acyl-coenzyme A:cholesterol Acyltransferase 1 (ACAT1) from H293 Cells and Binding Studies Between the Enzyme and Substrates Using Difference Intrinsic Fluorescence Spectroscopy
  Biochemistry. Nov, 2010  |   Pubmed ID: 20964445
• Chronic Infusion of Salusin-alpha and -beta Exerts Opposite Effects on Atherosclerotic Lesion Development in Apolipoprotein E-deficient Mice
  Atherosclerosis. Sep, 2010  |   Pubmed ID: 20684826
• Preventive Effects of Heregulin-beta1 on Macrophage Foam Cell Formation and Atherosclerosis
  Circulation Research. Aug, 2009  |   Pubmed ID: 19644050
• Increased Plasma Urotensin-II and Carotid Atherosclerosis Are Associated with Vascular Dementia
  Journal of Atherosclerosis and Thrombosis. Jun, 2009  |   Pubmed ID: 19638714
• Leptin Modulates ACAT1 Expression and Cholesterol Efflux from Human Macrophages
  American Journal of Physiology. Endocrinology and Metabolism. Aug, 2009  |   Pubmed ID: 19625677
• Human Urotensin II Promotes Hypertension and Atherosclerotic Cardiovascular Diseases
  Current Medicinal Chemistry. 2009  |   Pubmed ID: 19199921
• Angiotensin II Upregulates Acyl-CoA:cholesterol Acyltransferase-1 Via the Angiotensin II Type 1 Receptor in Human Monocyte-macrophages
  Hypertension Research : Official Journal of the Japanese Society of Hypertension. Sep, 2008  |   Pubmed ID: 18971559
• Chronic Urotensin II Infusion Enhances Macrophage Foam Cell Formation and Atherosclerosis in Apolipoprotein E-knockout Mice
  Journal of Hypertension. Oct, 2008  |   Pubmed ID: 18806619
• Serum Salusin-alpha Levels Are Decreased and Correlated Negatively with Carotid Atherosclerosis in Essential Hypertensive Patients
  Hypertension Research : Official Journal of the Japanese Society of Hypertension. Mar, 2008  |   Pubmed ID: 18497465
• Increased Plasma Urotensin-II Levels Are Associated with Diabetic Retinopathy and Carotid Atherosclerosis in Type 2 Diabetes
  Clinical Science (London, England : 1979). Dec, 2008  |   Pubmed ID: 18338983
• Impact of Salusin-alpha and -beta on Human Macrophage Foam Cell Formation and Coronary Atherosclerosis
  Circulation. Feb, 2008  |   Pubmed ID: 18212280
• Use of Serum Insulin-like Growth Factor-I Levels to Predict Psychiatric Non-response to Donepezil in Patients with Alzheimer's Disease
  Growth Hormone & IGF Research : Official Journal of the Growth Hormone Research Society and the International IGF Research Society. Feb, 2008  |   Pubmed ID: 17714966
• Increased Human Urotensin II Levels Are Correlated with Carotid Atherosclerosis in Essential Hypertension
  American Journal of Hypertension. Feb, 2007  |   Pubmed ID: 17261470
• Impact of Increased Plasma Serotonin Levels and Carotid Atherosclerosis on Vascular Dementia
  Atherosclerosis. Nov, 2007  |   Pubmed ID: 17049533
• Human Urotensin-II Potentiates the Mitogenic Effect of Mildly Oxidized Low-density Lipoprotein on Vascular Smooth Muscle Cells: Comparison with Other Vasoactive Agents and Hydrogen Peroxide
  Hypertension Research : Official Journal of the Japanese Society of Hypertension. Oct, 2006  |   Pubmed ID: 17283870
• Human Urotensin II As a Link Between Hypertension and Coronary Artery Disease
  Hypertension Research : Official Journal of the Japanese Society of Hypertension. Jun, 2006  |   Pubmed ID: 16940699
• Ndrg4 Enhances NGF-induced ERK Activation Uncoupled with Elk-1 Activation
  Journal of Cellular Biochemistry. May, 2006  |   Pubmed ID: 16408304
• Serotonin Acts As an Up-regulator of Acyl-coenzyme A:cholesterol Acyltransferase-1 in Human Monocyte-macrophages
  Atherosclerosis. Jun, 2006  |   Pubmed ID: 16157345
• Inhibitors of Acyl-coenzyme A: Cholesterol Acyltransferase
  Current Drug Targets. Cardiovascular & Haematological Disorders. Dec, 2005  |   Pubmed ID: 16503866
• Relationship Between Serum Insulin-like Growth Factor-1 Levels and Alzheimer's Disease and Vascular Dementia
  Journal of the American Geriatrics Society. Oct, 2005  |   Pubmed ID: 16181175
• Human Urotensin II Accelerates Foam Cell Formation in Human Monocyte-derived Macrophages
  Hypertension (Dallas, Tex. : 1979). Oct, 2005  |   Pubmed ID: 16172428
• High Prevalence of Chlamydia Pneumoniae Antibodies and Increased High-sensitive C-reactive Protein in Patients with Vascular Dementia
  Journal of the American Geriatrics Society. Apr, 2005  |   Pubmed ID: 15817002
• [Acyl-coenzyme A: Cholesterol Acyltransferase (ACAT)]
  Nihon Rinsho. Japanese Journal of Clinical Medicine. Dec, 2004  |   Pubmed ID: 15658270
• Genomic Organization, Expression, and Comparative Analysis of Noncoding Region of the Rat Ndrg4 Gene
  Gene. Jan, 2004  |   Pubmed ID: 14693380
• Acyl-coenzyme A:cholesterol Acyltransferase Inhibitors for Controlling Hypercholesterolemia and Atherosclerosis
  Current Opinion in Investigational Drugs (London, England : 2000). Sep, 2003  |   Pubmed ID: 14582454
• Advanced Glycation End Products (AGE) Inhibit Scavenger Receptor Class B Type I-mediated Reverse Cholesterol Transport: a New Crossroad of AGE to Cholesterol Metabolism
  Journal of Atherosclerosis and Thrombosis. 2003  |   Pubmed ID: 12621157