Alan J. Davidson

Publications

• The Dynamics of Metabolic Characterization in IPSC-Derived Kidney Organoid Differentiation a Comparative Omics Approach
  Frontiers in Genetics. 2021  |   Pubmed ID: 33643392
• Human Urinal Cell Reprogramming: Synthetic 3D Peptide Hydrogels Enhance Induced Pluripotent Stem Cell Population Homogeneity
  ACS Biomaterials Science & Engineering. 11, 2020  |   Pubmed ID: 33449655
• Protocol for Large-Scale Production of Kidney Organoids from Human Pluripotent Stem Cells
  STAR Protocols. Dec, 2020  |   Pubmed ID: 33377044
• SOX9 Promotes Stress-responsive Transcription of VGF Nerve Growth Factor Inducible Gene in Renal Tubular Epithelial Cells
  The Journal of Biological Chemistry. 11, 2020  |   Pubmed ID: 32887795
• ADAM10 Mediates Ectopic Proximal Tubule Development and Renal Fibrosis Through Notch Signalling
  The Journal of Pathology. 11, 2020  |   Pubmed ID: 32715474
• Common Variants Coregulate Expression of GBA and Modifier Genes to Delay Parkinson's Disease Onset
  Movement Disorders : Official Journal of the Movement Disorder Society. 08, 2020  |   Pubmed ID: 32557794
• The Utility of Human Kidney Organoids in Modeling Kidney Disease
  Seminars in Nephrology. 03, 2020  |   Pubmed ID: 32303281
• Use of Human Induced Pluripotent Stem Cells and Kidney Organoids To Develop a Cysteamine/mTOR Inhibition Combination Therapy for Cystinosis
  Journal of the American Society of Nephrology : JASN. 05, 2020  |   Pubmed ID: 32198276
• Evaluation of Cisplatin-induced Injury in Human Kidney Organoids
  American Journal of Physiology. Renal Physiology. 04, 2020  |   Pubmed ID: 32150447
• Transcriptional Profiling of the Zebrafish Proximal Tubule
  American Journal of Physiology. Renal Physiology. 08, 2019  |   Pubmed ID: 31188030
• Mind the Gap: Renal Tubule Responses to Injury and the Role of Cxcl12 and Myc
  Annals of Translational Medicine. Mar, 2019  |   Pubmed ID: 31032310
• Enhancing Regeneration After Acute Kidney Injury by Promoting Cellular Dedifferentiation in Zebrafish
  Disease Models & Mechanisms. 04, 2019  |   Pubmed ID: 30890583
• Turning Mesoderm into Kidney
  Seminars in Cell & Developmental Biology. 07, 2019  |   Pubmed ID: 30172050
• The Role of Macrophages During Acute Kidney Injury: Destruction and Repair
  Pediatric Nephrology (Berlin, Germany). 04, 2019  |   Pubmed ID: 29383444
• A Novel Mechanism of Gland Formation in Zebrafish Involving Transdifferentiation of Renal Epithelial Cells and Live Cell Extrusion
  ELife. 11, 2018  |   Pubmed ID: 30394875
• A Simple Bioreactor-Based Method to Generate Kidney Organoids From Pluripotent Stem Cells
  Stem Cell Reports. 08, 2018  |   Pubmed ID: 30033089
• Transgenic Xenopus Laevis Line for In Vivo Labeling of Nephrons Within the Kidney
  Genes. Apr, 2018  |   Pubmed ID: 29642376
• The Zebrafish Kidney Mutant Zeppelin Reveals That Brca2/fancd1 is Essential for Pronephros Development
  Developmental Biology. Aug, 2017  |   Pubmed ID: 28579318
• Zebrafish Pronephros Development
  Results and Problems in Cell Differentiation. 2017  |   Pubmed ID: 28409341
• Wnt8a Expands the Pool of Embryonic Kidney Progenitors in Zebrafish
  Developmental Biology. 05, 2017  |   Pubmed ID: 28359809
• The Vital Dye CDr10b Labels the Zebrafish Mid-Intestine and Lumen
  Molecules (Basel, Switzerland). Mar, 2017  |   Pubmed ID: 28335401
• Pronephric Tubule Formation in Zebrafish: Morphogenesis and Migration
  Pediatric Nephrology (Berlin, Germany). 02, 2017  |   Pubmed ID: 26942753
• Derivation of Corneal Keratocyte-Like Cells from Human Induced Pluripotent Stem Cells
  PloS One. 2016  |   Pubmed ID: 27792791
• Caudal Migration and Proliferation of Renal Progenitors Regulates Early Nephron Segment Size in Zebrafish
  Scientific Reports. 10, 2016  |   Pubmed ID: 27759103
• BMP and Retinoic Acid Regulate Anterior-posterior Patterning of the Non-axial Mesoderm Across the Dorsal-ventral Axis
  Nature Communications. 07, 2016  |   Pubmed ID: 27406002
• The Small Molecule Probe PT-Yellow Labels the Renal Proximal Tubules in Zebrafish
  Chemical Communications (Cambridge, England). 2015  |   Pubmed ID: 25407666
• Kidney Injury and Regeneration in Zebrafish
  Seminars in Nephrology. Jul, 2014  |   Pubmed ID: 25217272
• Kidney Regeneration in Fish
  Nephron. Experimental Nephrology. 2014  |   Pubmed ID: 24854639
• Hnf1beta and Nephron Segmentation
  Pediatric Nephrology (Berlin, Germany). Apr, 2014  |   Pubmed ID: 24190171
• Kidney Regeneration: Common Themes from the Embryo to the Adult
  Pediatric Nephrology (Berlin, Germany). Apr, 2014  |   Pubmed ID: 24005792
• A Cdx4-Sall4 Regulatory Module Controls the Transition from Mesoderm Formation to Embryonic Hematopoiesis
  Stem Cell Reports. 2013  |   Pubmed ID: 24286030
• Histone Deacetylase Inhibitor Enhances Recovery After AKI
  Journal of the American Society of Nephrology : JASN. May, 2013  |   Pubmed ID: 23620402
• A Zebrafish Model of Conditional Targeted Podocyte Ablation and Regeneration
  Kidney International. Jun, 2013  |   Pubmed ID: 23466998
• HNF1β is Essential for Nephron Segmentation During Nephrogenesis
  Journal of the American Society of Nephrology : JASN. Jan, 2013  |   Pubmed ID: 23160512
• Wt1a、 Foxc1a 和 Rbpj 的槽口调解员物理交互，并规管在斑马鱼中足细胞的形成。
  Developmental Biology. Oct, 2011  |   Pubmed ID: 21871448
• 斑马鱼 Nephrogenesis 涉及动态时空表达变化在肾祖细胞和视黄酸和 Irx3b 的重要信号。
  Developmental Dynamics : an Official Publication of the American Association of Anatomists. Aug, 2011  |   Pubmed ID: 21761484
• 斑马鱼肾脏发展： 基本科学的转化研究。
  Birth Defects Research. Part C, Embryo Today : Reviews. Jun, 2011  |   Pubmed ID: 21671354
• Cdx 基因和维甲酸的相互作用调节早期心脏发育。
  Developmental Biology. Jun, 2011  |   Pubmed ID: 21466798
• 未知的水域： Nephrogenesis 和肾再生的鱼和哺乳动物。
  Pediatric Nephrology (Berlin, Germany). Sep, 2011  |   Pubmed ID: 21336813
• 成人肾单位祖细胞能够肾再生的斑马鱼的标识。
  Nature. Feb, 2011  |   Pubmed ID: 21270795
• 斑马鱼 Wnt9a 表示，在咽外胚层，是口感和较低的下巴发展所必需的。
  Mechanisms of Development. Jan-Feb, 2011  |   Pubmed ID: 21093584
• 斑马鱼肾脏发育。
  Methods in Cell Biology. 2010  |   Pubmed ID: 21111220
• 视黄酸和 Scl 的相互作用控制原始血发展。
  Blood. Jul, 2010  |   Pubmed ID: 20410509
• 作用和神经系统-1 (雾-1） 的朋友斑马鱼血发育过程监管。
  Blood. Nov, 2009  |   Pubmed ID: 19729519
• 铜绿假单胞菌感染的斑马鱼涉及主机和病原的决定因素。
  Infection and Immunity. Apr, 2009  |   Pubmed ID: 19168742
• 斑马鱼肠分化需要 Cdx1b，功能等同的哺乳动物 Cdx2。
  Gastroenterology. Nov, 2008  |   Pubmed ID: 18804112
• Montalcino，斑马鱼模型高档进口染化卟啉病。
  Experimental Hematology. Sep, 2008  |   Pubmed ID: 18550261
• BMP 和 Wnt 通过 Cdx Hox 通路的激活指定造血的命运。
  Cell Stem Cell. Jan, 2008  |   Pubmed ID: 18371423
• Cdx 基因和维甲酸控制的定位和分割的斑马鱼鳜鱼。
  PLoS Genetics. Oct, 2007  |   Pubmed ID: 17953490
• Cdx4 Dysregulates Hox 基因表达和单独或与 Meis1a 合作在小鼠模型中生成急性髓细胞白血病。
  Proceedings of the National Academy of Sciences of the United States of America. Nov, 2006  |   Pubmed ID: 17068127
• Bmp 信号持续对斑马鱼的泄殖腔发展至关重要。
  Development (Cambridge, England). Jun, 2006  |   Pubmed ID: 16672335
• 骶管相关的同源盒基因 Cdx1a 和 Cdx4 冗余行事，以规管 Hox 基因表达与斑马鱼胚胎发生过程中假定的造血干细胞的形成。
  Developmental Biology. Apr, 2006  |   Pubmed ID: 16457800
• 虚谷氧还蛋白 5 揭示了 Fe S 群集所需的脊椎动物因子合成。
  Nature. Aug, 2005  |   Pubmed ID: 16110529
• 调节造血和血管发育过程中斑马鱼 Lmo2 启动子。
  Developmental Biology. May, 2005  |   Pubmed ID: 15893977
• 斑马鱼 Scl 功能独立在造血和内皮细胞的发展。
  Developmental Biology. Jan, 2005  |   Pubmed ID: 15617691
• 香醍漫步斑马鱼突变提供系祖特定中断转铁蛋白受体 1 的模型。
  Development (Cambridge, England). Dec, 2004  |   Pubmed ID: 15563524
• Mll 依赖 Hox 程序驱动器造血祖扩张。
  Current Biology : CB. Nov, 2004  |   Pubmed ID: 15556871
• 斑马鱼造血 '通用' (和 '原始') 指南。
  Oncogene. Sep, 2004  |   Pubmed ID: 15378083
• 表达式和重复黏 1 和黏-2 基因在发展中国家斑马鱼的映射。
  Gene Expression Patterns : GEP. Jul, 2004  |   Pubmed ID: 15183302
• Cdx4 突变体不能指定血祖细胞，可以由多个 Hox 基因救出。
  Nature. Sep, 2003  |   Pubmed ID: 13679919
• 斑马鱼表皮生长因子受体活性的抑制作用导致心血管缺陷。
  Mechanisms of Development. Jul, 2003  |   Pubmed ID: 12915231
• 特定细胞的有丝分裂缺陷和 Dyserythropoiesis 伴系祖带 3 缺失。
  Nature Genetics. May, 2003  |   Pubmed ID: 12669066
• 生物医学。爱、 荣誉、 和保护 （肝脏）。
  Science (New York, N.Y.). Feb, 2003  |   Pubmed ID: 12574609
• 需要建立斑马鱼的血管完整性的雷达。
  Developmental Biology. Nov, 2002  |   Pubmed ID: 12413901
• 黏 1 是血管的发展需要，是依赖 VEGF 的血管新生在斑马鱼中的调解员。
  Proceedings of the National Academy of Sciences of the United States of America. Aug, 2002  |   Pubmed ID: 12142468