Alan J. Simmons Department of Cell and Developmental Biology Vanderbilt University Biography Publications Institution JoVE Articles Alan J. Simmons has not added a biography. If you are Alan J. Simmons and would like to personalize this page please email our Author Liaison for assistance. Publications Combinatorial Transcriptional Profiling of Mouse and Human Enteric Neurons Identifies Shared and Disparate Subtypes In Situ Gastroenterology. Feb, 2021 | Pubmed ID: 33010250 Clinically Adaptable Polymer Enables Simultaneous Spatial Analysis of Colonic Tissues and Biofilms NPJ Biofilms and Microbiomes. 09, 2020 | Pubmed ID: 32973205 Succinate Produced by Intestinal Microbes Promotes Specification of Tuft Cells to Suppress Ileal Inflammation Gastroenterology. 12, 2020 | Pubmed ID: 32828819 An Interspecies Translation Model Implicates Integrin Signaling in Infliximab-resistant Inflammatory Bowel Disease Science Signaling. 08, 2020 | Pubmed ID: 32753478 Dual Indexed Library Design Enables Compatibility of In-Drop Single-cell RNA-sequencing with ExAMP Chemistry Sequencing Platforms BMC Genomics. Jul, 2020 | Pubmed ID: 32616006 Coregulator Sin3a Promotes Postnatal Murine β-Cell Fitness by Regulating Genes in Ca Homeostasis, Cell Survival, Vesicle Biosynthesis, Glucose Metabolism, and Stress Response Diabetes. 06, 2020 | Pubmed ID: 32245798 Heterogeneity and Dynamics of Active Kras-induced Dysplastic Lineages from Mouse Corpus Stomach Nature Communications. 12, 2019 | Pubmed ID: 31804471 High Dietary Salt-induced Dendritic Cell Activation Underlies Microbial Dysbiosis-associated Hypertension JCI Insight. 06, 2019 | Pubmed ID: 31162138 Novel Kidney Dissociation Protocol and Image-based Flow Cytometry Facilitate Improved Analysis of Injured Proximal Tubules American Journal of Physiology. Renal Physiology. 05, 2019 | Pubmed ID: 30759021 Neurog3-Independent Methylation Is the Earliest Detectable Mark Distinguishing Pancreatic Progenitor Identity Developmental Cell. 01, 2019 | Pubmed ID: 30620902 Single-Cell Mass Cytometry of Archived Human Epithelial Tissue for Decoding Cancer Signaling Pathways Methods in Molecular Biology (Clifton, N.J.). 2019 | Pubmed ID: 30465206 Quantitative Assessment of Cell Population Diversity in Single-cell Landscapes PLoS Biology. 10, 2018 | Pubmed ID: 30346945 Unsupervised Trajectory Analysis of Single-Cell RNA-Seq and Imaging Data Reveals Alternative Tuft Cell Origins in the Gut Cell Systems. 01, 2018 | Pubmed ID: 29153838 The ErbB3 Receptor Tyrosine Kinase Negatively Regulates Paneth Cells by PI3K-dependent Suppression of Atoh1 Cell Death and Differentiation. 05, 2017 | Pubmed ID: 28304405 Deciphering Tumor Heterogeneity from FFPE Tissues: Its Promise and Challenges Molecular & Cellular Oncology. 2017 | Pubmed ID: 28197533 Impaired Coordination Between Signaling Pathways is Revealed in Human Colorectal Cancer Using Single-cell Mass Cytometry of Archival Tissue Blocks Science Signaling. 10, 2016 | Pubmed ID: 27729552 Cytometry-based Single-cell Analysis of Intact Epithelial Signaling Reveals MAPK Activation Divergent from TNF-α-induced Apoptosis In vivo Molecular Systems Biology. Oct, 2015 | Pubmed ID: 26519361 Multiscale Analysis of the Murine Intestine for Modeling Human Diseases Integrative Biology : Quantitative Biosciences from Nano to Macro. Jul, 2015 | Pubmed ID: 26040649 Direct Detection of Isolevuglandins in Tissues Using a D11 scFv-Alkaline Phosphatase Fusion Protein and Immunofluorescence Cassandra Warden*1, Alan J. Simmons*2, Lejla Pasic3, Ashley Pitzer4,6, Sean S. Davies4, Justin H. Layer5, Raymond L. Mernaugh3, Annet Kirabo4,6 1Vanderbilt Eye Institute, Vanderbilt University Medical Center, 2Department of Cell and Developmental Biology, Vanderbilt University, 3Department of Biochemistry, Vanderbilt University, 4Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, 5Division of Hematology and Oncology, Indiana University School of Medicine, 6Department of Molecular Physiology and Biophysics, Vanderbilt University JoVE 62603 Biology
Direct Detection of Isolevuglandins in Tissues Using a D11 scFv-Alkaline Phosphatase Fusion Protein and Immunofluorescence Cassandra Warden*1, Alan J. Simmons*2, Lejla Pasic3, Ashley Pitzer4,6, Sean S. Davies4, Justin H. Layer5, Raymond L. Mernaugh3, Annet Kirabo4,6 1Vanderbilt Eye Institute, Vanderbilt University Medical Center, 2Department of Cell and Developmental Biology, Vanderbilt University, 3Department of Biochemistry, Vanderbilt University, 4Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, 5Division of Hematology and Oncology, Indiana University School of Medicine, 6Department of Molecular Physiology and Biophysics, Vanderbilt University JoVE 62603 Biology
