Alan W. Flake Division of General, Thoracic, and Fetal Surgery, Center for Fetal Research Children's Hospital of Philadelphia Biography Publications Institution JoVE Articles Alan W. Flake has not added a biography. If you are Alan W. Flake and would like to personalize this page please email our Author Liaison for assistance. Publications Congenital Pulmonary Airway Malformation: Advances and Controversies The Lancet. Child & Adolescent Health. Apr, 2018 | Pubmed ID: 30169300 Fetal Surgery for Spina Bifida Aperta Archives of Disease in Childhood. Fetal and Neonatal Edition. Jul, 2018 | Pubmed ID: 30006470 Reduced Oxygen Concentration for the Resuscitation of Infants with Congenital Diaphragmatic Hernia Journal of Perinatology : Official Journal of the California Perinatal Association. Jul, 2018 | Pubmed ID: 29887609 Preclinical Canine Model of Graft-versus-Host Disease After In Utero Hematopoietic Cell Transplantation Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation. Sep, 2018 | Pubmed ID: 29802901 Complex Gastroschisis: Clinical Spectrum and Neonatal Outcomes at a Referral Center Journal of Pediatric Surgery. Oct, 2018 | Pubmed ID: 29628208 Pumpless Arteriovenous Extracorporeal Membrane Oxygenation: A Novel Mode of Respiratory Support in a Lamb Model of Congenital Diaphragmatic Hernia Journal of Pediatric Surgery. Aug, 2018 | Pubmed ID: 29605270 Short-Term Neurodevelopmental Outcome in Children Born With High-Risk Congenital Lung Lesions The Annals of Thoracic Surgery. Jun, 2018 | Pubmed ID: 29438655 The Influence of Gestational Age, Mode of Delivery and Abdominal Wall Closure Method on the Surgical Outcome of Neonates with Uncomplicated Gastroschisis Pediatric Surgery International. Apr, 2018 | Pubmed ID: 29417204 Lung Function and Pulmonary Artery Blood Flow Following Prenatal Maternal Retinoic Acid and Imatinib in the Nitrofen Model of Congenital Diaphragmatic Hernia Journal of Pediatric Surgery. Sep, 2018 | Pubmed ID: 29409619 Umbilical Cannulation Optimizes Circuit Flows in Premature Lambs Supported by the EXTra-uterine Environment for Neonatal Development (EXTEND) The Journal of Physiology. May, 2018 | Pubmed ID: 29392729 Safety and Efficacy of Fetal Surgery Techniques to Close a Spina Bifida Defect in the Fetal Lamb Model: A Systematic Review Prenatal Diagnosis. Mar, 2018 | Pubmed ID: 29388237 Rate and Risk Factors Associated with Autism Spectrum Disorder in Congenital Diaphragmatic Hernia Journal of Autism and Developmental Disorders. Jun, 2018 | Pubmed ID: 29383650 Short-Term Neurodevelopmental Outcome in Congenital Diaphragmatic Hernia: The Impact of Extracorporeal Membrane Oxygenation and Timing of Repair Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. Jan, 2018 | Pubmed ID: 29303891 Attitudes of Paediatric and Obstetric Specialists Towards Prenatal Surgery for Lethal and Non-lethal Conditions Journal of Medical Ethics. Apr, 2018 | Pubmed ID: 29018178 Amniotic Fluid Concentrations of Glial Fibrillary Acidic Protein Do Not Correlate with Prenatal Metrics in Fetuses with Myelomeningocele Fetal Diagnosis and Therapy. 2018 | Pubmed ID: 28768252 Right Congenital Diaphragmatic Hernias: Is There a Correlation Between Prenatal Lung Volume and Postnatal Survival, As in Isolated Left Diaphragmatic Hernias? Fetal Diagnosis and Therapy. 2018 | Pubmed ID: 28319942 Weighing the Social and Ethical Considerations of Maternal-Fetal Surgery Pediatrics. Dec, 2017 | Pubmed ID: 29101225 Growth Trajectory and Neurodevelopmental Outcome in Infants with Congenital Diaphragmatic Hernia Journal of Pediatric Surgery. Dec, 2017 | Pubmed ID: 29079316 Fetal Intervention: Improving Evidence and Expanding Applications Seminars in Fetal & Neonatal Medicine. 12, 2017 | Pubmed ID: 29037820 An EXTrauterine Environment for Neonatal Development: EXTENDING Fetal Physiology Beyond the Womb Seminars in Fetal & Neonatal Medicine. 12, 2017 | Pubmed ID: 28551277 Responsible Surgical Innovation and Research in Maternal-fetal Surgery Seminars in Fetal & Neonatal Medicine. 12, 2017 | Pubmed ID: 28551276 Acceptability of In Utero Hematopoietic Cell Transplantation for Sickle Cell Disease Medical Decision Making : an International Journal of the Society for Medical Decision Making. 11, 2017 | Pubmed ID: 28490230 An Extra-uterine System to Physiologically Support the Extreme Premature Lamb Nature Communications. Apr, 2017 | Pubmed ID: 28440792 Specialty-Based Variation in Applying Maternal-Fetal Surgery Trial Evidence Fetal Diagnosis and Therapy. 2017 | Pubmed ID: 28301843 Induction of Immune Tolerance to Foreign Protein Via Adeno-Associated Viral Vector Gene Transfer in Mid-Gestation Fetal Sheep PloS One. 2017 | Pubmed ID: 28141818 Prenatal Growth Characteristics of Lymphatic Malformations Journal of Pediatric Surgery. Jan, 2017 | Pubmed ID: 27836363 Neurodevelopmental Outcomes at 5years of Age in Congenital Diaphragmatic Hernia Journal of Pediatric Surgery. Mar, 2017 | Pubmed ID: 27622588 Management and Outcomes of Scoliosis in Children with Congenital Diaphragmatic Hernia Journal of Pediatric Surgery. Dec, 2016 | Pubmed ID: 28029369 Enhanced in Utero Allogeneic Engraftment in Mice After Mobilizing Fetal HSCs by α4β1/7 Inhibition Blood. 11, 2016 | Pubmed ID: 27650329 Fetal Intrapericardial Teratoma: Natural History and Management Including Successful in Utero Surgery American Journal of Obstetrics and Gynecology. Dec, 2016 | Pubmed ID: 27530489 Improved Pulmonary Function in the Nitrofen Model of Congenital Diaphragmatic Hernia Following Prenatal Maternal Dexamethasone And/or Sildenafil Pediatric Research. 10, 2016 | Pubmed ID: 27376883 Right- Versus Left-sided Congenital Diaphragmatic Hernia: a Comparative Outcomes Analysis Journal of Pediatric Surgery. Jun, 2016 | Pubmed ID: 27342009 Rate of Increase of Lung-to-head Ratio over the Course of Gestation is Predictive of Survival in Left-sided Congenital Diaphragmatic Hernia Journal of Pediatric Surgery. May, 2016 | Pubmed ID: 27261559 Vector Serotype Screening for Use in Ovine Perinatal Lung Gene Therapy Journal of Pediatric Surgery. Jun, 2016 | Pubmed ID: 27032612 Younger Gestational Age is Associated with Increased Risk of Adverse Neurodevelopmental Outcome During Infancy in Congenital Diaphragmatic Hernia Journal of Pediatric Surgery. Jul, 2016 | Pubmed ID: 26831532 The Intravenous Route of Injection Optimizes Engraftment and Survival in the Murine Model of In Utero Hematopoietic Cell Transplantation Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation. Jun, 2016 | Pubmed ID: 26797401 How to Treat a Neonate with Duodenal Atresia and Intrapancreatic Choledochocele Causing Persistent Hyperbilirubinemia: A Case Report International Journal of Surgery Case Reports. 2016 | Pubmed ID: 26701845 Delayed Abdominal Closure After Congenital Diaphragmatic Hernia Repair Journal of Pediatric Surgery. Feb, 2016 | Pubmed ID: 26653950 Effect of Single and Multiple Courses of Maternal Betamethasone on Prenatal Congenital Lung Lesion Growth and Fetal Survival Journal of Pediatric Surgery. Jan, 2016 | Pubmed ID: 26526208 Complete Tissue Coverage Achieved by Scaffold-based Tissue Engineering in the Fetal Sheep Model of Myelomeningocele Biomaterials. Jan, 2016 | Pubmed ID: 26520044 In Utero Stem Cell Transplantation and Gene Therapy: Recent Progress and the Potential for Clinical Application Best Practice & Research. Clinical Obstetrics & Gynaecology. Feb, 2016 | Pubmed ID: 26483174 Experience with Thoracoscopic Repair of Long Gap Esophageal Atresia in Neonates Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A. Nov, 2015 | Pubmed ID: 26485521 Correction of Murine Hemoglobinopathies by Prenatal Tolerance Induction and Postnatal Nonmyeloablative Allogeneic BM Transplants Blood. Sep, 2015 | Pubmed ID: 26124498 The First 100 Infant Thoracoscopic Lobectomies: Observations Through the Learning Curve and Comparison to Open Lobectomy Journal of Pediatric Surgery. Nov, 2015 | Pubmed ID: 26100691 Frequency and Complications of Inguinal Hernia Repair in Giant Omphalocele Journal of Pediatric Surgery. Oct, 2015 | Pubmed ID: 26078212 Axillary Lymphatic Malformations: Prenatal Evaluation and Postnatal Outcomes Journal of Pediatric Surgery. Oct, 2015 | Pubmed ID: 25959530 Life-Long Transgene Expression in Skeletal Muscle Without Transduction of Satellite Cells Following Embryonic Myogenic Progenitor Transduction by Lentivirus Administered in Utero Stem Cells and Development. Aug, 2015 | Pubmed ID: 25915576 Immune Tolerance Induction Using Fetal Directed Placental Injection in Rodent Models: a Murine Model PloS One. 2015 | Pubmed ID: 25876079 Neurodevelopmental Outcome at One Year of Age in Congenital Diaphragmatic Hernia Infants Not Treated with Extracorporeal Membrane Oxygenation Journal of Pediatric Surgery. Jun, 2015 | Pubmed ID: 25818204 Systemic Hypertension in Giant Omphalocele: An Underappreciated Association Journal of Pediatric Surgery. Sep, 2015 | Pubmed ID: 25783355 Consensus Statement from the First International Conference for in Utero Stem Cell Transplantation and Gene Therapy Frontiers in Pharmacology. 2015 | Pubmed ID: 25713535 Patient Characteristics Are Important Determinants of Neurodevelopmental Outcome During Infancy in Giant Omphalocele Early Human Development. Mar, 2015 | Pubmed ID: 25676186 Ex Utero Intrapartum Treatment (EXIT) in the Management of Cervical Lymphatic Malformation Journal of Pediatric Surgery. Feb, 2015 | Pubmed ID: 25638626 Prenatal Diagnosis of Esophageal Bronchus--first Report of a Rare Foregut Malformation in Utero Journal of Pediatric Surgery. Feb, 2015 | Pubmed ID: 25638625 Thoracoamniotic Shunts for the Management of Fetal Lung Lesions and Pleural Effusions: a Single-institution Review and Predictors of Survival in 75 Cases Journal of Pediatric Surgery. Feb, 2015 | Pubmed ID: 25638624 Brain-type Natriuretic Peptide Levels Correlate with Pulmonary Hypertension and Requirement for Extracorporeal Membrane Oxygenation in Congenital Diaphragmatic Hernia Journal of Pediatric Surgery. Feb, 2015 | Pubmed ID: 25638615 Timing of Repair of Congenital Diaphragmatic Hernia in Patients Supported by Extracorporeal Membrane Oxygenation (ECMO) Journal of Pediatric Surgery. Feb, 2015 | Pubmed ID: 25638614 Fetal Myelomeningocele Repair: the Post-MOMS Experience at the Children's Hospital of Philadelphia Fetal Diagnosis and Therapy. 2015 | Pubmed ID: 25138132 Tissue Engineering Strategies for Fetal Myelomeningocele Repair in Animal Models Fetal Diagnosis and Therapy. 2015 | Pubmed ID: 25060746 The Role of Echocardiography in the Intraoperative Management of the Fetus Undergoing Myelomeningocele Repair Fetal Diagnosis and Therapy. 2015 | Pubmed ID: 25059830 Developmental Stage Determines Efficiency of Gene Transfer to Muscle Satellite Cells by in Utero Delivery of Adeno-associated Virus Vector Serotype 2/9 Molecular Therapy. Methods & Clinical Development. 2014 | Pubmed ID: 26015979 Pulmonary Hypertension in Giant Omphalocele Infants Journal of Pediatric Surgery. Dec, 2014 | Pubmed ID: 25487480 Outcomes of Prenatally Diagnosed Lung Lesions in Multigestational Pregnancies Fetal Diagnosis and Therapy. 2014 | Pubmed ID: 25378348 Percutaneous Minimal-access Fetoscopic Surgery for Myelomeningocele - Not So Minimal! Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology. Nov, 2014 | Pubmed ID: 25363896 In Utero Stem Cell and Gene Therapy: Current Status and Future Perspectives European Journal of Pediatric Surgery : Official Journal of Austrian Association of Pediatric Surgery ... [et Al] = Zeitschrift Fur Kinderchirurgie. Jun, 2014 | Pubmed ID: 24945440 Incidence and Factors Associated with Sensorineural and Conductive Hearing Loss Among Survivors of Congenital Diaphragmatic Hernia Journal of Pediatric Surgery. Jun, 2014 | Pubmed ID: 24888829 Stable Long-term Mixed Chimerism Achieved in a Canine Model of Allogeneic in Utero Hematopoietic Cell Transplantation Blood. Sep, 2014 | Pubmed ID: 24869940 In Utero Lung Gene Transfer Using Adeno-associated Viral and Lentiviral Vectors in Mice Human Gene Therapy Methods. Jun, 2014 | Pubmed ID: 24660751 The Contribution of Hiatal Hernia to Severe Gastroesophageal Reflux Disease in Patients with Gastroschisis Journal of Pediatric Surgery. Mar, 2014 | Pubmed ID: 24650464 Open Fetal Surgery for Central Bronchial Atresia Fetal Diagnosis and Therapy. 2014 | Pubmed ID: 24457616 Urologic and Anorectal Complications of Sacrococcygeal Teratomas: Prenatal and Postnatal Predictors Journal of Pediatric Surgery. Jan, 2014 | Pubmed ID: 24439598 Perinatal Management of Congenital Oropharyngeal Tumors: the Ex Utero Intrapartum Treatment (EXIT) Approach Journal of Pediatric Surgery. Oct, 2013 | Pubmed ID: 24094948 Fetal Surgical Intervention: Progress and Perspectives Pediatric Surgery International. May, 2013 | Pubmed ID: 23552956 In Utero Hematopoietic Cell Transplantation--recent Progress and the Potential for Clinical Application Cytotherapy. May, 2013 | Pubmed ID: 23415921 Stem Cell and Genetic Therapies for the Fetus Seminars in Pediatric Surgery. Feb, 2013 | Pubmed ID: 23395147 Preschool Neurological Assessment in Congenital Diaphragmatic Hernia Survivors: Outcome and Perinatal Factors Associated with Neurodevelopmental Impairment Early Human Development. Jun, 2013 | Pubmed ID: 23333410 Intra-amniotic Transient Transduction of the Periderm with a Viral Vector Encoding TGFβ3 Prevents Cleft Palate in Tgfβ3(-/-) Mouse Embryos Molecular Therapy : the Journal of the American Society of Gene Therapy. Jan, 2013 | Pubmed ID: 23089732 A 2-year-old Girl with Abdominal Pain After an Action Sure to Attract Attention Pediatric Emergency Care. Dec, 2012 | Pubmed ID: 23222115 Ex Utero Intrapartum Treatment in the Management of Giant Cervical Teratomas Journal of Pediatric Surgery. Jun, 2012 | Pubmed ID: 22703795 Use of Magnetic Resonance Imaging in Prenatal Prognosis of the Fetus with Isolated Left Congenital Diaphragmatic Hernia Prenatal Diagnosis. Aug, 2012 | Pubmed ID: 22674674 Animal Models for Prenatal Gene Therapy: Rodent Models for Prenatal Gene Therapy Methods in Molecular Biology (Clifton, N.J.). 2012 | Pubmed ID: 22648774 Use of Manipulated Stem Cells for Prenatal Therapy Methods in Molecular Biology (Clifton, N.J.). 2012 | Pubmed ID: 22648772 Fetal MRI-calculated Total Lung Volumes in the Prediction of Short-term Outcome in Giant Omphalocele: Preliminary Findings Fetal Diagnosis and Therapy. 2012 | Pubmed ID: 22572017 Maternal-fetal Surgery for Structural Malformations Best Practice & Research. Clinical Obstetrics & Gynaecology. Oct, 2012 | Pubmed ID: 22542765 Early Neurodevelopmental Outcome of Infants with High-risk Fetal Lung Lesions Fetal Diagnosis and Therapy. 2012 | Pubmed ID: 22539010 Patch Repair for Congenital Diaphragmatic Hernia: is It Really a Problem? Journal of Pediatric Surgery. Apr, 2012 | Pubmed ID: 22498374 Abnormal Brain Development and Maturation on Magnetic Resonance Imaging in Survivors of Severe Congenital Diaphragmatic Hernia Journal of Pediatric Surgery. Mar, 2012 | Pubmed ID: 22424337 Factor IX Expression in Skeletal Muscle of a Severe Hemophilia B Patient 10 Years After AAV-mediated Gene Transfer Blood. Mar, 2012 | Pubmed ID: 22271447 Early Delivery As an Alternative Management Strategy for Selected High-risk Fetal Sacrococcygeal Teratomas Journal of Pediatric Surgery. Jul, 2011 | Pubmed ID: 21763829 Fluoroscopic-assisted Endobronchial Intubation for Single-lung Ventilation in Infants Paediatric Anaesthesia. Jun, 2011 | Pubmed ID: 21492317 Genetic Therapy for the Fetus: a Once in a Lifetime Opportunity Human Gene Therapy. Apr, 2011 | Pubmed ID: 21486158 Laparoscopic Hepaticoduodenostomy Versus Open Hepaticoduodenostomy for Reconstruction After Resection of Choledochal Cyst Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A. May, 2011 | Pubmed ID: 21443442 Amniotic Fluid Levels of Glial Fibrillary Acidic Protein in Fetal Rats with Retinoic Acid Induced Myelomeningocele: a Potential Marker for Spinal Cord Injury American Journal of Obstetrics and Gynecology. Feb, 2011 | Pubmed ID: 21284970 Hepaticoduodenostomy Vs Hepaticojejunostomy for Reconstruction After Resection of Choledochal Cyst Journal of Pediatric Surgery. Jan, 2011 | Pubmed ID: 21238669 Fetal Surgery: Progress and Perspectives Advances in Pediatrics. 2010 | Pubmed ID: 21056747 Increased Susceptibility to Liver Damage from Pneumoperitoneum in a Murine Model of Biliary Atresia Journal of Pediatric Surgery. Sep, 2010 | Pubmed ID: 20850622 Neurodevelopmental Outcome of Infants with Congenital Diaphragmatic Hernia Prospectively Enrolled in an Interdisciplinary Follow-up Program Journal of Pediatric Surgery. Sep, 2010 | Pubmed ID: 20850617 Predicting the Severity of Congenital High Airway Obstruction Syndrome Journal of Pediatric Surgery. Aug, 2010 | Pubmed ID: 20713212 Prenatal Diagnosis and Postnatal Resection of Intraabdominal Enteric Duplications Journal of Pediatric Surgery. Jul, 2010 | Pubmed ID: 20638544 Robust in Vivo Transduction of Nervous System and Neural Stem Cells by Early Gestational Intra Amniotic Gene Transfer Using Lentiviral Vector Molecular Therapy : the Journal of the American Society of Gene Therapy. Sep, 2010 | Pubmed ID: 20571539 Reproductive Outcomes in Subsequent Pregnancies After a Pregnancy Complicated by Open Maternal-fetal Surgery (1996-2007) American Journal of Obstetrics and Gynecology. Sep, 2010 | Pubmed ID: 20537307 Gastroschisis in Mice Lacking Aortic Carboxypeptidase-like Protein is Associated with a Defect in Neuromuscular Development of the Eviscerated Intestine Pediatric Research. Jul, 2010 | Pubmed ID: 20386491 Prospective, Interdisciplinary Follow-up of Children with Prenatally Diagnosed Giant Omphalocele: Short-term Neurodevelopmental Outcome Journal of Pediatric Surgery. Apr, 2010 | Pubmed ID: 20385277 Platelets Regulate Lymphatic Vascular Development Through CLEC-2-SLP-76 Signaling Blood. Jul, 2010 | Pubmed ID: 20363774 A Tissue Engineering Approach for Prenatal Closure of Myelomeningocele with Gelatin Sponges Incorporating Basic Fibroblast Growth Factor Tissue Engineering. Part A. May, 2010 | Pubmed ID: 19954327 Stem Cell and Genetic Therapies for the Fetus Seminars in Fetal & Neonatal Medicine. Feb, 2010 | Pubmed ID: 19540822 The Effects of Fetal Surgery on Retinopathy of Prematurity Development Ophthalmology and Eye Diseases. 2009 | Pubmed ID: 23861606 Maternal Alloantibodies Induce a Postnatal Immune Response That Limits Engraftment Following in Utero Hematopoietic Cell Transplantation in Mice The Journal of Clinical Investigation. Sep, 2009 | Pubmed ID: 19652363 Prenatal Stem Cell Transplantation and Gene Therapy Clinics in Perinatology. Jun, 2009 | Pubmed ID: 19559331 In Utero Meconium Passage in Fetuses and Newborns with Myelomeningocele Journal of Neurosurgery. Pediatrics. Feb, 2009 | Pubmed ID: 19278315 Haploidentical in Utero Hematopoietic Cell Transplantation Improves Phenotype and Can Induce Tolerance for Postnatal Same-donor Transplants in the Canine Leukocyte Adhesion Deficiency Model Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation. Mar, 2009 | Pubmed ID: 19203720 Correction of Murine ADAMTS13 Deficiency by Hematopoietic Progenitor Cell-mediated Gene Therapy Blood. Mar, 2009 | Pubmed ID: 19141866 Sacrococcygeal Teratomas: Prenatal Surveillance, Growth and Pregnancy Outcome Fetal Diagnosis and Therapy. 2009 | Pubmed ID: 19122459 Correction of ADAMTS13 Deficiency by in Utero Gene Transfer of Lentiviral Vector Encoding ADAMTS13 Genes Molecular Therapy : the Journal of the American Society of Gene Therapy. Jan, 2009 | Pubmed ID: 18957966 In Utero Repair of Myelomeningocele: Rationale, Initial Clinical Experience and a Randomized Controlled Prospective Clinical Trial Neuroembryology and Aging. Mar, 2008 | Pubmed ID: 22479081 In Vivo Differentiation Potential of Mesenchymal Stem Cells: Prenatal and Postnatal Model Systems Transfusion Medicine and Hemotherapy : Offizielles Organ Der Deutschen Gesellschaft Fur Transfusionsmedizin Und Immunhamatologie. 2008 | Pubmed ID: 21547121 Intradural Inclusion Cysts Following in Utero Closure of Myelomeningocele: Clinical Implications and Follow-up Findings Journal of Neurosurgery. Pediatrics. Dec, 2008 | Pubmed ID: 19035686 Fetal Tracheal Occlusion for Severe Congenital Diaphragmatic Hernia in Humans: a Morphometric Study of Lung Parenchyma and Muscularization of Pulmonary Arterioles Journal of Pediatric Surgery. Oct, 2008 | Pubmed ID: 18926205 Prenatal Course and Postnatal Management of Peripheral Bronchial Atresia: Association with Congenital Cystic Adenomatoid Malformation of the Lung Fetal Diagnosis and Therapy. 2008 | Pubmed ID: 18753756 Apoptotic Cell-mediated Immunoregulation of Dendritic Cells Does Not Require IC3b Opsonization Journal of Immunology (Baltimore, Md. : 1950). Sep, 2008 | Pubmed ID: 18713972 Repair of Indirect Inguinal Hernias by "laparoscopic Joining of the Edges" Surgical Laparoscopy, Endoscopy & Percutaneous Techniques. Jun, 2008 | Pubmed ID: 18574416 In Utero Hematopoietic Stem Cell Transplantation: Progress Toward Clinical Application Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation. Jul, 2008 | Pubmed ID: 18541191 Cystic Adenomatoid Malformations Are Induced by Localized FGF10 Overexpression in Fetal Rat Lung American Journal of Respiratory Cell and Molecular Biology. Sep, 2008 | Pubmed ID: 18421016 Prenatal Ultrasonographic Gastrointestinal Abnormalities in Fetuses with Gastroschisis Do Not Correlate with Postnatal Outcomes Journal of Pediatric Surgery. Apr, 2008 | Pubmed ID: 18405710 Main Bronchus Occlusion for Treatment of Congenital Diaphragmatic Hernia in Fetal Lambs Journal of Pediatric Surgery. Apr, 2008 | Pubmed ID: 18405706 Outcomes After Postnatal Resection of Prenatally Diagnosed Asymptomatic Cystic Lung Lesions Journal of Pediatric Surgery. Mar, 2008 | Pubmed ID: 18358291 Murine Bone Marrow Derived Stromal Progenitor Cells Fail to Prevent or Treat Acute Graft-versus-host Disease British Journal of Haematology. Apr, 2008 | Pubmed ID: 18318768 Emergent Excision of a Prenatally Diagnosed Sacrococcygeal Teratoma Paediatric Anaesthesia. May, 2008 | Pubmed ID: 18312529 OEIS Sequence--a Rare Congenital Anomaly with Prenatal Evaluation and Postnatal Outcome in Six Cases Prenatal Diagnosis. Feb, 2008 | Pubmed ID: 18236426 Pulmonary Vascular Malformations Seminars in Pediatric Surgery. Feb, 2008 | Pubmed ID: 18158137 Morphologic Analysis of the Neuromuscular Development of the Anorectal Unit in Fetal Rats with Retinoic Acid Induced Myelomeningocele Neuroscience Letters. Jan, 2008 | Pubmed ID: 18063303 Efficient in Vivo Targeting of Epidermal Stem Cells by Early Gestational Intraamniotic Injection of Lentiviral Vector Driven by the Keratin 5 Promoter Molecular Therapy : the Journal of the American Society of Gene Therapy. Jan, 2008 | Pubmed ID: 17923841 Liver Position and Lung-to-head Ratio for Prediction of Extracorporeal Membrane Oxygenation and Survival in Isolated Left Congenital Diaphragmatic Hernia American Journal of Obstetrics and Gynecology. Oct, 2007 | Pubmed ID: 17904987 Postnatal Chest Wall Deformities After Fetal Thoracoamniotic Shunting for Congenital Cystic Adenomatoid Malformation Fetal Diagnosis and Therapy. 2007 | Pubmed ID: 17652932 Persistent Expression of HF.IX After Tolerance Induction by in Utero or Neonatal Administration of AAV-1-F.IX in Hemophilia B Mice Molecular Therapy : the Journal of the American Society of Gene Therapy. Sep, 2007 | Pubmed ID: 17565352 Effect of Maternal Betamethasone Administration on Prenatal Congenital Cystic Adenomatoid Malformation Growth and Fetal Survival Fetal Diagnosis and Therapy. 2007 | Pubmed ID: 17556826 Does a Myelomeningocele Sac Compared to No Sac Result in Decreased Postnatal Leg Function Following Maternal Fetal Surgery for Spina Bifida Aperta? Fetal Diagnosis and Therapy. 2007 | Pubmed ID: 17556822 Enhanced Epithelial Gap Closure and Increased Angiogenesis in Wounds of Diabetic Mice Treated with Adult Murine Bone Marrow Stromal Progenitor Cells Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society. May-Jun, 2007 | Pubmed ID: 17537122 Murine Bone Marrow Stromal Progenitor Cells Elicit an in Vivo Cellular and Humoral Alloimmune Response Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation. Apr, 2007 | Pubmed ID: 17382248 Gene Transfer to Ocular Stem Cells by Early Gestational Intraamniotic Injection of Lentiviral Vector Molecular Therapy : the Journal of the American Society of Gene Therapy. Mar, 2007 | Pubmed ID: 17245352 Targeted Gene Transfer to Fetal Rat Lung Interstitium by Ultrasound-guided Intrapulmonary Injection Molecular Therapy : the Journal of the American Society of Gene Therapy. Feb, 2007 | Pubmed ID: 17235312 Evidence for an Immune Barrier After in Utero Hematopoietic-cell Transplantation Blood. Feb, 2007 | Pubmed ID: 17023584 Structural and Functional Characterization of Bladder Smooth Muscle in Fetal Rats with Retinoic Acid-induced Myelomeningocele American Journal of Physiology. Renal Physiology. Jan, 2007 | Pubmed ID: 16940565 The Regulatory Role of Stromal Microenvironments in Fetal Hematopoietic Ontogeny Stem Cell Reviews. 2006 | Pubmed ID: 17625260 Prenatal Glucocorticoids Improve Lung Morphology and Partially Restores Surfactant MRNA Expression in Lambs with Diaphragmatic Hernia Undergoing Fetal Tracheal Occlusion Pediatric Pulmonology. Dec, 2006 | Pubmed ID: 17048255 Comparison of Outcomes After Laparoscopic and Open Pyloromyotomy at a High-volume Pediatric Teaching Hospital Journal of Pediatric Surgery. Oct, 2006 | Pubmed ID: 17011267 Diagnosis and Characterization of Fetal Sacrococcygeal Teratoma with Prenatal MRI AJR. American Journal of Roentgenology. Oct, 2006 | Pubmed ID: 16985105 CD26 Inhibition Enhances Allogeneic Donor-cell Homing and Engraftment After in Utero Hematopoietic-cell Transplantation Blood. Dec, 2006 | Pubmed ID: 16954501 Congenital Pulmonary Lymphangiectasis Sequence: a Rare, Heterogeneous, and Lethal Etiology for Prenatal Pleural Effusion Prenatal Diagnosis. Nov, 2006 | Pubmed ID: 16941717 Prenatal Transplantation of Cytokine-stimulated Marrow Improves Early Chimerism in a Resistant Strain Combination but Results in Poor Long-term Engraftment Experimental Hematology. Sep, 2006 | Pubmed ID: 16939821 Prenatal Glucocorticoids and Exogenous Surfactant Therapy Improve Respiratory Function in Lambs with Severe Diaphragmatic Hernia Following Fetal Tracheal Occlusion Pediatric Research. Aug, 2006 | Pubmed ID: 16864691 Successful Revision of Portoenterostomy in an Infant with Biliary Atresia Journal of Pediatric Surgery. Jul, 2006 | Pubmed ID: 16818040 Tracheal Occlusion in Fetal Rats Alters Expression of Mesenchymal Nuclear Transcription Factors Without Affecting Surfactant Protein Expression Journal of Pediatric Surgery. Apr, 2006 | Pubmed ID: 16567192 Busulfan-conditioned Bone Marrow Transplantation Results in High-level Allogeneic Chimerism in Mice Made Tolerant by in Utero Hematopoietic Cell Transplantation Experimental Hematology. Mar, 2006 | Pubmed ID: 16543070 Severe Pulmonary Hypoplasia Associated with Giant Cervical Teratomas Journal of Pediatric Surgery. Jan, 2006 | Pubmed ID: 16410139 Cystic Adenomatoid Malformation of the Lung: Review of Genetics, Prenatal Diagnosis, and in Utero Treatment American Journal of Medical Genetics. Part A. Jan, 2006 | Pubmed ID: 16353256 The Ex Utero Intrapartum Therapy Procedure for High-risk Fetal Lung Lesions Journal of Pediatric Surgery. Jun, 2005 | Pubmed ID: 15991193 Impact of Continuous Intraoperative Monitoring on Outcomes in Open Fetal Surgery Fetal Diagnosis and Therapy. Jul-Aug, 2005 | Pubmed ID: 15980648 Management of Fetal Mediastinal Teratoma Journal of Pediatric Surgery. Jan, 2005 | Pubmed ID: 15868589 Surfactant Protein Expression is Increased in the Ipsilateral but Not Contralateral Lungs of Fetal Sheep with Left-sided Diaphragmatic Hernia Pediatric Pulmonology. Apr, 2005 | Pubmed ID: 15704191 Transduction of Satellite Cells After Prenatal Intramuscular Administration of Lentiviral Vectors The Journal of Gene Medicine. Jan, 2005 | Pubmed ID: 15515139 Reconstitution of Hematopoiesis Following Intrauterine Transplantation of Stem Cells Methods in Molecular Medicine. 2005 | Pubmed ID: 15492389 In Utero Stem Cell Transplantation Best Practice & Research. Clinical Obstetrics & Gynaecology. Dec, 2004 | Pubmed ID: 15582548 Optimized Large-scale Production of High Titer Lentivirus Vector Pseudotypes Journal of Virological Methods. Dec, 2004 | Pubmed ID: 15542136 Surgeons and Stem Cells: a Pragmatic Perspective on Shifting Paradigms Surgery. Nov, 2004 | Pubmed ID: 15523389 Reproductive Outcomes After Pregnancy Complicated by Maternal-fetal Surgery American Journal of Obstetrics and Gynecology. Oct, 2004 | Pubmed ID: 15507978 Heregulin Ameliorates the Dystrophic Phenotype in Mdx Mice Proceedings of the National Academy of Sciences of the United States of America. Sep, 2004 | Pubmed ID: 15365169 Favorable Neuroblastoma Genes and Molecular Therapeutics of Neuroblastoma Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Sep, 2004 | Pubmed ID: 15355914 Acute Cardiovascular Effects of Fetal Surgery in the Human Circulation. Sep, 2004 | Pubmed ID: 15353490 Thoracoamniotic Shunts: Fetal Treatment of Pleural Effusions and Congenital Cystic Adenomatoid Malformations Fetal Diagnosis and Therapy. Sep-Oct, 2004 | Pubmed ID: 15305098 Prenatally Diagnosed Giant Omphaloceles: Short- and Long-term Outcomes Prenatal Diagnosis. Jun, 2004 | Pubmed ID: 15229842 Mesenchymal Stem Cells: Paradoxes of Passaging Experimental Hematology. May, 2004 | Pubmed ID: 15145209 Sacrococcygeal Teratoma: Prenatal Assessment, Fetal Intervention, and Outcome Journal of Pediatric Surgery. Mar, 2004 | Pubmed ID: 15017565 Right Congenital Diaphragmatic Hernia: Prenatal Assessment and Outcome Journal of Pediatric Surgery. Mar, 2004 | Pubmed ID: 15017545 Complete Allogeneic Hematopoietic Chimerism Achieved by in Utero Hematopoietic Cell Transplantation and Cotransplantation of LLME-treated, MHC-sensitized Donor Lymphocytes Experimental Hematology. Mar, 2004 | Pubmed ID: 15003315 The Conceptual Application of Systems Theory to Stem Cell Biology: a Matter of Context Blood Cells, Molecules & Diseases. Jan-Feb, 2004 | Pubmed ID: 14757414 Abnormal Umbilical Cord Doppler Sonograms May Predict Impending Demise in Fetuses with Sacrococcygeal Teratoma. A Report of Two Cases Fetal Diagnosis and Therapy. Jan-Feb, 2004 | Pubmed ID: 14646415 In Utero Hematopoietic Cell Transplantation: What Are the Important Questions? Fetal Diagnosis and Therapy. Jan-Feb, 2004 | Pubmed ID: 14646411 Long-term Transgene Expression in Cardiac and Skeletal Muscle Following Fetal Administration of Adenoviral or Adeno-associated Viral Vectors in Mice The Journal of Gene Medicine. Nov, 2003 | Pubmed ID: 14601131 Abnormal Umbilical Cord Dopplers May Predict Impending Demise in Fetuses with Sacrococcygeal Teratoma. A Report of 2 Cases Fetal Diagnosis and Therapy. Nov-Dec, 2003 | Pubmed ID: 14564114 Fetal Myelomeningocele Repair: Short-term Clinical Outcomes American Journal of Obstetrics and Gynecology. Aug, 2003 | Pubmed ID: 14520222 Stem Cell and Genetic Therapies for the Fetus Seminars in Pediatric Surgery. Aug, 2003 | Pubmed ID: 12961115 Epinephrine Inhibits Tracheal Occlusion Induced Lung Growth in Fetal Sheep Fetal Diagnosis and Therapy. Sep-Oct, 2003 | Pubmed ID: 12913344 Chorioamniotic Membrane Separation Following Open Fetal Surgery: Pregnancy Outcome Fetal Diagnosis and Therapy. Sep-Oct, 2003 | Pubmed ID: 12913340 Congenital High Airway Obstruction Syndrome: Natural History and Management Journal of Pediatric Surgery. Jun, 2003 | Pubmed ID: 12778398 Mixed Chimerism Following in Utero Hematopoietic Stem Cell Transplantation in Murine Models of Hemoglobinopathy Experimental Hematology. Feb, 2003 | Pubmed ID: 12591283 History of Fetal Diagnosis and Therapy: Children's Hospital of Philadelphia Experience Fetal Diagnosis and Therapy. Mar-Apr, 2003 | Pubmed ID: 12576740 Temporary Tracheal Occlusion in Fetal Sheep with Lung Hypoplasia Does Not Improve Postnatal Lung Function Journal of Applied Physiology (Bethesda, Md. : 1985). Mar, 2003 | Pubmed ID: 12571135 Surgery in the Human Fetus: the Future The Journal of Physiology. Feb, 2003 | Pubmed ID: 12562950 Management of Congenital Lung Lesions Seminars in Pediatric Surgery. Feb, 2003 | Pubmed ID: 12520469 AAV-mediated Factor IX Gene Transfer to Skeletal Muscle in Patients with Severe Hemophilia B Blood. Apr, 2003 | Pubmed ID: 12515715 Genetic Therapies for the Fetus Clinical Obstetrics and Gynecology. Sep, 2002 | Pubmed ID: 12370608 Efficient Transduction of Liver and Muscle After in Utero Injection of Lentiviral Vectors with Different Pseudotypes Molecular Therapy : the Journal of the American Society of Gene Therapy. Sep, 2002 | Pubmed ID: 12231171 High-level Allogeneic Chimerism Achieved by Prenatal Tolerance Induction and Postnatal Nonmyeloablative Bone Marrow Transplantation Blood. Sep, 2002 | Pubmed ID: 12200389 The Ex-utero Intrapartum Treatment Current Opinion in Pediatrics. Aug, 2002 | Pubmed ID: 12130912 Complete Allogeneic Hematopoietic Chimerism Achieved by a Combined Strategy of in Utero Hematopoietic Stem Cell Transplantation and Postnatal Donor Lymphocyte Infusion Blood. Aug, 2002 | Pubmed ID: 12130490 Influence of Congenital Heart Disease on Survival in Children with Congenital Diaphragmatic Hernia The Journal of Pediatrics. Jul, 2002 | Pubmed ID: 12091847 Engraftment of Bone Marrow and Fetal Liver Cells After in Utero Transplantation in MDX Mice Journal of Pediatric Surgery. Jul, 2002 | Pubmed ID: 12077771 Human Mesenchymal Stem Cells: Insights from a Surrogate in Vivo Assay System Cells, Tissues, Organs. 2002 | Pubmed ID: 12021494 Bone Marrow Tissue Engineering Tissue Engineering. Feb, 2002 | Pubmed ID: 11886662 The EXIT Procedure: Experience and Outcome in 31 Cases Journal of Pediatric Surgery. Mar, 2002 | Pubmed ID: 11877660 Cystic Adenomatoid Malformation Volume Ratio Predicts Outcome in Prenatally Diagnosed Cystic Adenomatoid Malformation of the Lung Journal of Pediatric Surgery. Mar, 2002 | Pubmed ID: 11877643 The Natural History of Prenatally Diagnosed Conjoined Twins Journal of Pediatric Surgery. Mar, 2002 | Pubmed ID: 11877639 In Utero Stem Cell Transplantation for the Treatment of Genetic Diseases Schweizerische Medizinische Wochenschrift. Nov, 1999 | Pubmed ID: 10603645 In Utero Hematopoietic Stem Cell Transplantation: Ontogenic Opportunities and Biologic Barriers Blood. Oct, 1999 | Pubmed ID: 10498587 The Current Status and Future Potential of Fetal Intervention: Image is Everything Computerized Medical Imaging and Graphics : the Official Journal of the Computerized Medical Imaging Society. Jan-Feb, 1999 | Pubmed ID: 10091869 In Utero Transplantation for Thalassemia Annals of the New York Academy of Sciences. Jun, 1998 | Pubmed ID: 9668552 In Utero Hematopoietic Stem Cell Transplantation. A Status Report JAMA. Sep, 1997 | Pubmed ID: 9302247 Внутривенно и интраамниальной In Utero трансплантации мышиных модели Nicholas J. Ahn1, John D. Stratigis1, Barbara E. Coons1, Alan W. Flake1, Hyun-Duck Nah-Cederquist2, William H. Peranteau1 1Division of General, Thoracic, and Fetal Surgery, Center for Fetal Research, Children's Hospital of Philadelphia, 2Division of Plastic Reconstructive Surgery, Center for Fetal Research, Children's Hospital of Philadelphia JoVE 58047 Developmental Biology
Внутривенно и интраамниальной In Utero трансплантации мышиных модели Nicholas J. Ahn1, John D. Stratigis1, Barbara E. Coons1, Alan W. Flake1, Hyun-Duck Nah-Cederquist2, William H. Peranteau1 1Division of General, Thoracic, and Fetal Surgery, Center for Fetal Research, Children's Hospital of Philadelphia, 2Division of Plastic Reconstructive Surgery, Center for Fetal Research, Children's Hospital of Philadelphia JoVE 58047 Developmental Biology
