Alberto Inga Department CIBIO University of Trento Biography Publications Institution JoVE Articles Alberto Inga has not added a biography. If you are Alberto Inga and would like to personalize this page please email our Author Liaison for assistance. Publications LncRNA EPR Controls Epithelial Proliferation by Coordinating Cdkn1a Transcription and MRNA Decay Response to TGF-β Nature Communications. 04, 2019 | Pubmed ID: 31036808 Reactivation of TAp73 Tumor Suppressor by Protoporphyrin IX, a Metabolite of Aminolevulinic Acid, Induces Apoptosis in 53-deficient Cancer Cells Cell Division. 2018 | Pubmed ID: 30603043 Synthesis of 2,6-Diamino-Substituted Purine Derivatives and Evaluation of Cell Cycle Arrest in Breast and Colorectal Cancer Cells Molecules (Basel, Switzerland). Aug, 2018 | Pubmed ID: 30103421 A Highly Specific SpCas9 Variant is Identified by in Vivo Screening in Yeast Nature Biotechnology. 03, 2018 | Pubmed ID: 29431739 Identification of a Core TP53 Transcriptional Program with Highly Distributed Tumor Suppressive Activity Genome Research. 10, 2017 | Pubmed ID: 28904012 Inherited Determinants of Early Recurrent Somatic Mutations in Prostate Cancer Nature Communications. 06, 2017 | Pubmed ID: 28663546 DIMP53-1: a Novel Small-molecule Dual Inhibitor of P53-MDM2/X Interactions with Multifunctional P53-dependent Anticancer Properties Molecular Oncology. 06, 2017 | Pubmed ID: 28296148 The Structure Formed by Inverted Repeats in P53 Response Elements Determines the Transactivation Activity of P53 Protein Biochemical and Biophysical Research Communications. 01, 2017 | Pubmed ID: 28007599 Human Transcription Factors in Yeast: the Fruitful Examples of P53 and NF-кB FEMS Yeast Research. 11, 2016 | Pubmed ID: 27683095 C-Myc Targeted Regulators of Cell Metabolism in a Transgenic Mouse Model of Papillary Lung Adenocarcinoma Oncotarget. Oct, 2016 | Pubmed ID: 27602772 The Ribonucleic Complex HuR-MALAT1 Represses CD133 Expression and Suppresses Epithelial-Mesenchymal Transition in Breast Cancer Cancer Research. 05, 2016 | Pubmed ID: 27197265 Reactivation of Wild-type and Mutant P53 by Tryptophanolderived Oxazoloisoindolinone SLMP53-1, a Novel Anticancer Small-molecule Oncotarget. Jan, 2016 | Pubmed ID: 26735173 The CDKN2A/p16(INK) (4a) 5'UTR Sequence and Translational Regulation: Impact of Novel Variants Predisposing to Melanoma Pigment Cell & Melanoma Research. Mar, 2016 | Pubmed ID: 26581427 The 5'-untranslated Region of P16INK4a Melanoma Tumor Suppressor Acts As a Cellular IRES, Controlling MRNA Translation Under Hypoxia Through YBX1 Binding Oncotarget. Nov, 2015 | Pubmed ID: 26498684 Enhanced Cytotoxicity of Prenylated Chalcone Against Tumour Cells Via Disruption of the P53-MDM2 Interaction Life Sciences. Dec, 2015 | Pubmed ID: 26475964 Decoding C-Myc Networks of Cell Cycle and Apoptosis Regulated Genes in a Transgenic Mouse model of Papillary Lung Adenocarcinomas Oncotarget. Oct, 2015 | Pubmed ID: 26427040 RiboAbacus: a Model Trained on Polyribosome Images Predicts Ribosome Density and Translational Efficiency from Mammalian Transcriptomes Nucleic Acids Research. Dec, 2015 | Pubmed ID: 26240374 Quantitative Analysis of NF-κB Transactivation Specificity Using a Yeast-Based Functional Assay PloS One. 2015 | Pubmed ID: 26147604 Whole-genome Cartography of P53 Response Elements Ranked on Transactivation Potential BMC Genomics. Jun, 2015 | Pubmed ID: 26081755 In-silico Identification and Functional Validation of Allele-dependent AR Enhancers Oncotarget. Mar, 2015 | Pubmed ID: 25693204 Evolution of P53 Transactivation Specificity Through the Lens of a Yeast-based Functional Assay PloS One. 2015 | Pubmed ID: 25668429 Oxazoloisoindolinones with in Vitro Antitumor Activity Selectively Activate a P53-pathway Through Potential Inhibition of the P53-MDM2 Interaction European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences. Jan, 2015 | Pubmed ID: 25312347 Cooperative Interactions Between P53 and NFκB Enhance Cell Plasticity Oncotarget. Dec, 2014 | Pubmed ID: 25401416 ∆N-P63α and TA-P63α Exhibit Intrinsic Differences in Transactivation Specificities That Depend on Distinct Features of DNA Target Sites Oncotarget. Apr, 2014 | Pubmed ID: 24926492 TP53 Mutants in the Tower of Babel of Cancer Progression Human Mutation. Jun, 2014 | Pubmed ID: 24449472 Comparison of the Biological Effects of MMS and Me-lex, a Minor Groove Methylating Agent: Clarifying the Role of N3-methyladenine Mutation Research. Jan, 2014 | Pubmed ID: 24211855 Transcriptional Defect of an Inherited NKX2-5 Haplotype Comprising a SNP, a Nonsynonymous and a Synonymous Mutation, Associated with Human Congenital Heart Disease PloS One. 2013 | Pubmed ID: 24376681 A Cross-platform Comparison of Affymetrix and Agilent Microarrays Reveals Discordant MiRNA Expression in Lung Tumors of C-Raf Transgenic Mice PloS One. 2013 | Pubmed ID: 24265725 Identification of New P53 Target MicroRNAs by Bioinformatics and Functional Analysis BMC Cancer. Nov, 2013 | Pubmed ID: 24256616 Transactivation Specificity is Conserved Among P53 Family Proteins and Depends on a Response Element Sequence Code Nucleic Acids Research. Oct, 2013 | Pubmed ID: 23892287 P53 Family Members Modulate the Expression of PRODH, but Not PRODH2, Via Intronic P53 Response Elements PloS One. 2013 | Pubmed ID: 23861960 Interaction Between P53 and Estradiol Pathways in Transcriptional Responses to Chemotherapeutics Cell Cycle (Georgetown, Tex.). Apr, 2013 | Pubmed ID: 23518503 The TP53 Website: an Integrative Resource Centre for the TP53 Mutation Database and TP53 Mutant Analysis Nucleic Acids Research. Jan, 2013 | Pubmed ID: 23161690 Contribution of Yeast and Plant Research for Improving Human Health Journal of Biomedicine & Biotechnology. 2012 | Pubmed ID: 22851885 3-Methyl-3-deazaadenine, a Stable Isostere of N3-methyl-adenine, is Efficiently Bypassed by Replication in Vivo and by Transcription in Vitro DNA Repair. Aug, 2011 | Pubmed ID: 21676659 Dominant-negative Features of Mutant TP53 in Germline Carriers Have Limited Impact on Cancer Outcomes Molecular Cancer Research : MCR. Mar, 2011 | Pubmed ID: 21343334 The Coordinated P53 and Estrogen Receptor Cis-regulation at an FLT1 Promoter SNP is Specific to Genotoxic Stress and Estrogenic Compound PloS One. Apr, 2010 | Pubmed ID: 20422012 Altered-function P53 Missense Mutations Identified in Breast Cancers Can Have Subtle Effects on Transactivation Molecular Cancer Research : MCR. May, 2010 | Pubmed ID: 20407015 酵母作为开发功能分析研究人类P53的机箱 Paola Monti1, Bartolomeo Bosco2, Sara Gomes3, Lucilia Saraiva*3, Gilberto Fronza*1, Alberto Inga*2 1Mutagenesis and Cancer Prevention Unit, Ospedale Policlinico San Martino, 2Department CIBIO, University of Trento, 3LAQV/REQUIMTE, Laboratory of Microbiology, Faculty of Pharmacy, University of Porto JoVE 59071 Cancer Research
酵母作为开发功能分析研究人类P53的机箱 Paola Monti1, Bartolomeo Bosco2, Sara Gomes3, Lucilia Saraiva*3, Gilberto Fronza*1, Alberto Inga*2 1Mutagenesis and Cancer Prevention Unit, Ospedale Policlinico San Martino, 2Department CIBIO, University of Trento, 3LAQV/REQUIMTE, Laboratory of Microbiology, Faculty of Pharmacy, University of Porto JoVE 59071 Cancer Research