Alejandro Chavez Wyss Institute for Biologically Inspired Engineering Harvard University Biography Publications Institution JoVE Articles Alejandro Chavez has not added a biography. If you are Alejandro Chavez and would like to personalize this page please email our Author Liaison for assistance. Publications An Enhanced CRISPR Repressor for Targeted Mammalian Gene Regulation Nature Methods. Aug, 2018 | Pubmed ID: 30013045 Enhanced Bacterial Immunity and Mammalian Genome Editing Via RNA-Polymerase-Mediated Dislodging of Cas9 from Double-Strand DNA Breaks Molecular Cell. Jul, 2018 | Pubmed ID: 29979968 High-throughput Creation and Functional Profiling of DNA Sequence Variant Libraries Using CRISPR-Cas9 in Yeast Nature Biotechnology. Jul, 2018 | Pubmed ID: 29786095 An Integrated Genome-wide CRISPRa Approach to Functionalize LncRNAs in Drug Resistance Cell. Apr, 2018 | Pubmed ID: 29677511 Enabling Multiplexed Testing of Pooled Donor Cells Through Whole-genome Sequencing Genome Medicine. 04, 2018 | Pubmed ID: 29673390 CRISPR-based Genomic Tools for the Manipulation of Genetically Intractable Microorganisms Nature Reviews. Microbiology. Jun, 2018 | Pubmed ID: 29599458 Precise Cas9 Targeting Enables Genomic Mutation Prevention Proceedings of the National Academy of Sciences of the United States of America. 04, 2018 | Pubmed ID: 29555762 A CRISPR-Cas9-based Gene Drive Platform for Genetic Interaction Analysis in Candida Albicans Nature Microbiology. Oct, 2017 | Pubmed ID: 29062088 Programmable Transcriptional Repression in Mycobacteria Using an Orthogonal CRISPR Interference Platform Nature Microbiology. Feb, 2017 | Pubmed ID: 28165460 SgRNA Scorer 2.0: A Species-Independent Model To Predict CRISPR/Cas9 Activity ACS Synthetic Biology. 05, 2017 | Pubmed ID: 28146356 Comparison of Cas9 Activators in Multiple Species Nature Methods. 07, 2016 | Pubmed ID: 27214048 Cas9 GRNA Engineering for Genome Editing, Activation and Repression Nature Methods. Nov, 2015 | Pubmed ID: 26344044 Highly Efficient Cas9-mediated Transcriptional Programming Nature Methods. Apr, 2015 | Pubmed ID: 25730490 CRISPR Guide RNA Klonen für Säugetier-Systeme Sathiji Nageshwaran*1,2, Alejandro Chavez*1,2,3, Nan Cher Yeo1,2, Xiaoge Guo1,2, Alissa Lance-Byrne1, Angela Tung1, James J. Collins1,4,5,6,7, George M. Church1,2 1Wyss Institute for Biologically Inspired Engineering, Harvard University, 2Department of Genetics, Harvard Medical School, 3Department of Pathology, Massachusetts General Hospital, 4Institute for Medical Engineering & Science, Massachusetts Institute of Technology, 5Synthetic Biology Center, Massachusetts Institute of Technology, 6Department of Biological Engineering, Massachusetts Institute of Technology, 7Broad Institute JoVE 57998 Genetics
CRISPR Guide RNA Klonen für Säugetier-Systeme Sathiji Nageshwaran*1,2, Alejandro Chavez*1,2,3, Nan Cher Yeo1,2, Xiaoge Guo1,2, Alissa Lance-Byrne1, Angela Tung1, James J. Collins1,4,5,6,7, George M. Church1,2 1Wyss Institute for Biologically Inspired Engineering, Harvard University, 2Department of Genetics, Harvard Medical School, 3Department of Pathology, Massachusetts General Hospital, 4Institute for Medical Engineering & Science, Massachusetts Institute of Technology, 5Synthetic Biology Center, Massachusetts Institute of Technology, 6Department of Biological Engineering, Massachusetts Institute of Technology, 7Broad Institute JoVE 57998 Genetics
