In JoVE (1)
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Articles by Alessandro Aiazzi in JoVE
Isolation and Functional Characterization of Human Ventricular Cardiomyocytes from Fresh Surgical Samples Raffaele Coppini1, Cecila Ferrantini2, Alessandro Aiazzi2, Luca Mazzoni1, Laura Sartiani1, Alessandro Mugelli1, Corrado Poggesi2, Elisabetta Cerbai1 1Department NeuroFarBa, Division of Pharmacology, University of Florence, 2Department of Clinical and Experimental Medicine, Division of Physiology, University of Florence Current knowledge on the cellular basis of cardiac diseases mostly relies on studies on animal models. Here we describe and validate a novel method to obtain single viable cardiomyocytes from small surgical samples of human ventricular myocardium. Human ventricular myocytes can be used for electrophysiological studies and drug testing.