Alexander G. Obukhov

Publications

• HIV-Nef Protein Transfer to Endothelial Cells Requires Rac1 Activation and Leads to Endothelial Dysfunction: Implications for Statin Treatment in HIV Patients
  Circulation Research. Aug, 2019  |   Pubmed ID: 31451038
• Long-Term Diabetic Microenvironment Augments the Decay Rate of Capsaicin-Induced Currents in Mouse Dorsal Root Ganglion Neurons
  Molecules (Basel, Switzerland). 02, 2019  |   Pubmed ID: 30795543
• The TRPC6 Inhibitor, Larixyl Acetate, is Effective in Protecting Against Traumatic Brain Injury-induced Systemic Endothelial Dysfunction
  Journal of Neuroinflammation. Jan, 2019  |   Pubmed ID: 30704505
• Catechol Estrogens Stimulate Insulin Secretion in Pancreatic β-cells Via Activation of the Transient Receptor Potential A1 (TRPA1) Channel
  The Journal of Biological Chemistry. 02, 2019  |   Pubmed ID: 30587572
• R125H, W240S, C386R, and V507I SLC4A11 Mutations Associated with Corneal Endothelial Dystrophy Affect the Transporter Function but Not Trafficking in PS120 Cells
  Experimental Eye Research. 03, 2019  |   Pubmed ID: 30557570
• Small-molecule Caα⋅Caβ Antagonist Suppresses Neuronal Voltage-gated Calcium-channel Trafficking
  Proceedings of the National Academy of Sciences of the United States of America. 11, 2018  |   Pubmed ID: 30355767
• Phenylephrine, a Common Cold Remedy Active Ingredient, Suppresses Uterine Contractions Through CAMP Signalling
  Scientific Reports. Aug, 2018  |   Pubmed ID: 30076382
• Loss of Angiotensin-Converting Enzyme 2 Exacerbates Diabetic Retinopathy by Promoting Bone Marrow Dysfunction
  Stem Cells (Dayton, Ohio). Sep, 2018  |   Pubmed ID: 29761600
• Long-term Spironolactone Treatment Reduces Coronary TRPC Expression, Vasoconstriction, and Atherosclerosis in Metabolic Syndrome Pigs
  Basic Research in Cardiology. 09, 2017  |   Pubmed ID: 28756533
• Molecular Determinants of the Sensitivity to Gq/11-Phospholipase C-dependent Gating, Gd3+ Potentiation, and Ca2+ Permeability in the Transient Receptor Potential Canonical Type 5 (TRPC5) Channel
  The Journal of Biological Chemistry. 01, 2017  |   Pubmed ID: 27920205
• Endothelial Cell-Specific Deletion of P2Y2 Receptor Promotes Plaque Stability in Atherosclerosis-Susceptible ApoE-Null Mice
  Arteriosclerosis, Thrombosis, and Vascular Biology. 01, 2017  |   Pubmed ID: 27856454
• Novel Roles for Kv7 Channels in Shaping Histamine-Induced Contractions and Bradykinin-Dependent Relaxations in Pig Coronary Arteries
  PloS One. 2016  |   Pubmed ID: 26844882
• Human SLC4A11 Is a Novel NH3/H+ Co-transporter
  The Journal of Biological Chemistry. Jul, 2015  |   Pubmed ID: 26018076
• Primary Cilia Signaling Mediates Intraocular Pressure Sensation
  Proceedings of the National Academy of Sciences of the United States of America. Sep, 2014  |   Pubmed ID: 25143588
• Mechanisms Underlying Capsaicin Effects in Canine Coronary Artery: Implications for Coronary Spasm
  Cardiovascular Research. Sep, 2014  |   Pubmed ID: 24935430
• PKC-dependent Phosphorylation of the H1 Histamine Receptor Modulates TRPC6 Activity
  Cells. Apr, 2014  |   Pubmed ID: 24709960
• Furanocoumarins Are a Novel Class of Modulators for the Transient Receptor Potential Vanilloid Type 1 (TRPV1) Channel
  The Journal of Biological Chemistry. Apr, 2014  |   Pubmed ID: 24569998
• Contribution of Electromechanical Coupling Between Kv and Ca V1.2 Channels to Coronary Dysfunction in Obesity
  Basic Research in Cardiology. Sep, 2013  |   Pubmed ID: 23856709
• TLR4 Activation of TRPC6-dependent Calcium Signaling Mediates Endotoxin-induced Lung Vascular Permeability and Inflammation
  The Journal of Experimental Medicine. Oct, 2012  |   Pubmed ID: 23045603
• Constitutive Activity of TRPML2 and TRPML3 Channels Versus Activation by Low Extracellular Sodium and Small Molecules
  The Journal of Biological Chemistry. Jun, 2012  |   Pubmed ID: 22753890
• Altered Calcium Signaling in Colonic Smooth Muscle of Type 1 Diabetic Mice
  American Journal of Physiology. Gastrointestinal and Liver Physiology. Jan, 2012  |   Pubmed ID: 21979758
• Bromoenol Lactone Inhibits Voltage-gated Ca2+ and Transient Receptor Potential Canonical Channels
  The Journal of Pharmacology and Experimental Therapeutics. Nov, 2011  |   Pubmed ID: 21795434
• Small Molecule Activators of TRPML3
  Chemistry & Biology. Feb, 2010  |   Pubmed ID: 20189104
• Exercise Training Decreases Store-operated Ca2+entry Associated with Metabolic Syndrome and Coronary Atherosclerosis
  Cardiovascular Research. Feb, 2010  |   Pubmed ID: 19744946
• Canonical Transient Receptor Potential Channels Expression is Elevated in a Porcine Model of Metabolic Syndrome
  Molecular Endocrinology (Baltimore, Md.). May, 2009  |   Pubmed ID: 19221052
• In Vivo Identification and Manipulation of the Ca2+ Selectivity Filter in the Drosophila Transient Receptor Potential Channel
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jan, 2007  |   Pubmed ID: 17234592