Articles by Alexander Brinkmann in JoVE
Recording Temperature-induced Neuronal Activity through Monitoring Calcium Changes in the Olfactory Bulb of Xenopus laevis Alexander Brinkmann*1,2, Camille Okom*1,2, Eugen Kludt1,2,4, Detlev Schild1,2,3 1Institute of Neurophysiology and Cellular Biophysics, Georg-August-Universität Göttingen, 2Center for Nanoscale Microscopy and Molecular Physiology of the Brain, Georg-August-Universität Göttingen, 3DFG Excellence Cluster 171, Georg-August-Universität Göttingen, 4German Hearing Center Hannover Here we describe a protocol for measuring and analyzing temperature responses in the olfactory bulb of Xenopus laevis. Olfactory receptor neurons and mitral cells are differentially stained, after which calcium changes are recorded, reflecting a sensitivity of some neural networks in the bulb to temperature drops induced at the nose.
Other articles by Alexander Brinkmann on PubMed
What is the Effect of Obesity on Piperacillin and Meropenem Trough Concentrations in Critically Ill Patients? The Journal of Antimicrobial Chemotherapy. Mar, 2016 | Pubmed ID: 26702922 The objectives of this study were to determine the effects of obesity on unbound trough concentrations and on the achievement of pharmacokinetic (PK)/pharmacodynamic (PD) targets of piperacillin and meropenem in critically ill patients.