Alexander Staruschenko Department of Physiology Medical College of Wisconsin Biography Publications Institution JoVE Articles Alexander Staruschenko has not added a biography. If you are Alexander Staruschenko and would like to personalize this page please email our Author Liaison for assistance. Publications S&R Foundation 15th Anniversary The Physiologist. Sep, 2015 | Pubmed ID: 26442383 TRPC6 Channel As an Emerging Determinant of the Podocyte Injury Susceptibility in Kidney Diseases American Journal of Physiology. Renal Physiology. Jun, 2015 | Pubmed ID: 26084930 Inhibition of ENaC by Endothelin-1 Vitamins and Hormones. 2015 | Pubmed ID: 25817869 Acetylation Stimulates the Epithelial Sodium Channel by Reducing Its Ubiquitination and Degradation The Journal of Biological Chemistry. May, 2015 | Pubmed ID: 25787079 Cross-talk Between Insulin and IGF-1 Receptors in the Cortical Collecting Duct Principal Cells: Implication for ENaC-mediated Na+ Reabsorption American Journal of Physiology. Renal Physiology. Apr, 2015 | Pubmed ID: 25651558 Impaired Epithelial Na+ Channel Activity Contributes to Cystogenesis and Development of Autosomal Recessive Polycystic Kidney Disease in PCK Rats Pediatric Research. Jan, 2015 | Pubmed ID: 25279988 Role of Rho GDP Dissociation Inhibitor α in Control of Epithelial Sodium Channel (ENaC)-mediated Sodium Reabsorption The Journal of Biological Chemistry. Oct, 2014 | Pubmed ID: 25164814 Mutation of Plekha7 Attenuates Salt-sensitive Hypertension in the Rat Proceedings of the National Academy of Sciences of the United States of America. Sep, 2014 | Pubmed ID: 25136115 To Cleave or Not to Cleave: Role of ADAM17 in Cell Proliferation in PKD American Journal of Physiology. Renal Physiology. Sep, 2014 | Pubmed ID: 25056345 Epoxyeicosatrienoic Acid Analogue Lowers Blood Pressure Through Vasodilation and Sodium Channel Inhibition Clinical Science (London, England : 1979). Oct, 2014 | Pubmed ID: 24707975 Angiotensin II Has Acute Effects on TRPC6 Channels in Podocytes of Freshly Isolated Glomeruli Kidney International. Sep, 2014 | Pubmed ID: 24646854 PC and PKC: in Vivo Vs. in Vitro American Journal of Physiology. Renal Physiology. Mar, 2014 | Pubmed ID: 24370588 Pharmacological Characterization of the P2 Receptors Profile in the Podocytes of the Freshly Isolated Rat Glomeruli American Journal of Physiology. Cell Physiology. Nov, 2013 | Pubmed ID: 24048730 Arp2/3 Complex Inhibitors Adversely Affect Actin Cytoskeleton Remodeling in the Cultured Murine Kidney Collecting Duct M-1 Cells Cell and Tissue Research. Dec, 2013 | Pubmed ID: 24036843 Direct Inhibition of Basolateral Kir4.1/5.1 and Kir4.1 Channels in the Cortical Collecting Duct by Dopamine American Journal of Physiology. Renal Physiology. Nov, 2013 | Pubmed ID: 23986512 Orally Active Epoxyeicosatrienoic Acid Analog Attenuates Kidney Injury in Hypertensive Dahl Salt-sensitive Rat Hypertension. Nov, 2013 | Pubmed ID: 23980070 Aldosterone-dependent Trans-activation and Epigenetic Derepression of ENaC: Where is the Balance? American Journal of Physiology. Renal Physiology. Oct, 2013 | Pubmed ID: 23842778 Epidermal Growth Factors in the Kidney and Relationship to Hypertension American Journal of Physiology. Renal Physiology. Jul, 2013 | Pubmed ID: 23637204 Deficiency of Renal Cortical EGF Increases ENaC Activity and Contributes to Salt-sensitive Hypertension Journal of the American Society of Nephrology : JASN. Jun, 2013 | Pubmed ID: 23599382 Real-time Electrochemical Detection of ATP and H₂O₂ Release in Freshly Isolated Kidneys American Journal of Physiology. Renal Physiology. Jul, 2013 | Pubmed ID: 23594827 Detection of Endogenous Substances with Enzymatic Microelectrode Biosensors in the Kidney American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Jul, 2013 | Pubmed ID: 23594609 Regulation of ENaC in Mice Lacking Renal Insulin Receptors in the Collecting Duct FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Jul, 2013 | Pubmed ID: 23558339 Single-channel Analysis of TRPC Channels in the Podocytes of Freshly Isolated Glomeruli Methods in Molecular Biology (Clifton, N.J.). 2013 | Pubmed ID: 23529444 Recording Ion Channels in Isolated, Split-opened Tubules Methods in Molecular Biology (Clifton, N.J.). 2013 | Pubmed ID: 23529443 Direct Activation of ENaC by Angiotensin II: Recent Advances and New Insights Current Hypertension Reports. Feb, 2013 | Pubmed ID: 23180052 ROS Production As a Common Mechanism of ENaC Regulation by EGF, Insulin, and IGF-1 American Journal of Physiology. Cell Physiology. Jan, 2013 | Pubmed ID: 23135700 G-protein Signaling Modulator 1 Deficiency Accelerates Cystic Disease in an Orthologous Mouse Model of Autosomal Dominant Polycystic Kidney Disease Proceedings of the National Academy of Sciences of the United States of America. Dec, 2012 | Pubmed ID: 23236168 Regulation of Transport in the Connecting Tubule and Cortical Collecting Duct Comprehensive Physiology. Apr, 2012 | Pubmed ID: 23227301 Role of βPix in the Kidney Frontiers in Physiology. 2012 | Pubmed ID: 22654768 Angiotensin II Increases Activity of the Epithelial Na+ Channel (ENaC) in Distal Nephron Additively to Aldosterone The Journal of Biological Chemistry. Jan, 2012 | Pubmed ID: 22086923 Effects of Cytochrome P-450 Metabolites of Arachidonic Acid on the Epithelial Sodium Channel (ENaC) American Journal of Physiology. Renal Physiology. Sep, 2011 | Pubmed ID: 21697242 Cortical Actin Binding Protein Cortactin Mediates ENaC Activity Via Arp2/3 Complex FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Aug, 2011 | Pubmed ID: 21536685 NSAIDs Acutely Inhibit TRPC Channels in Freshly Isolated Rat Glomeruli Biochemical and Biophysical Research Communications. May, 2011 | Pubmed ID: 21473850 Novel Role of Rac1/WAVE Signaling Mechanism in Regulation of the Epithelial Na+ Channel Hypertension. May, 2011 | Pubmed ID: 21464391 Epidermal Growth Factor-mediated Proliferation and Sodium Transport in Normal and PKD Epithelial Cells Biochimica Et Biophysica Acta. Oct, 2011 | Pubmed ID: 20959142 The Actin Cytoskeleton and Small G Protein RhoA Are Not Involved in Flow-dependent Activation of ENaC BMC Research Notes. 2010 | Pubmed ID: 20663206 Regulation of ENaC-Mediated Sodium Reabsorption by Peroxisome Proliferator-Activated Receptors PPAR Research. 2010 | Pubmed ID: 20613963 Endothelin-1 Inhibits the Epithelial Na+ Channel Through BetaPix/14-3-3/Nedd4-2 Journal of the American Society of Nephrology : JASN. May, 2010 | Pubmed ID: 20338996 Contribution of TRPV1-TRPA1 Interaction to the Single Channel Properties of the TRPA1 Channel The Journal of Biological Chemistry. May, 2010 | Pubmed ID: 20231274 Intact Cytoskeleton is Required for Small G Protein Dependent Activation of the Epithelial Na+ Channel PloS One. 2010 | Pubmed ID: 20098689 EGF and Its Related Growth Factors Mediate Sodium Transport in MpkCCDc14 Cells Via ErbB2 (neu/HER-2) Receptor Journal of Cellular Physiology. Apr, 2010 | Pubmed ID: 20049896 Peroxisome Proliferator-activated Receptor Gamma Antagonists Decrease Na+ Transport Via the Epithelial Na+ Channel Molecular Pharmacology. Dec, 2009 | Pubmed ID: 19752200 Muscarinic M1 Modulation of Acid-sensing Ion Channels Neuroreport. Oct, 2009 | Pubmed ID: 19730136 Intrinsic Voltage Dependence of the Epithelial Na+ Channel is Masked by a Conserved Transmembrane Domain Tryptophan The Journal of Biological Chemistry. Sep, 2009 | Pubmed ID: 19620245 Regulation of ENaC Expression at the Cell Surface by Rab11 Biochemical and Biophysical Research Communications. Dec, 2008 | Pubmed ID: 18926797 Insight Toward Epithelial Na+ Channel Mechanism Revealed by the Acid-sensing Ion Channel 1 Structure IUBMB Life. Sep, 2008 | Pubmed ID: 18459164 Mechanisms of Non-steroid Anti-inflammatory Drugs Action on ASICs Expressed in Hippocampal Interneurons Journal of Neurochemistry. Jul, 2008 | Pubmed ID: 18410516 Ion Channel Regulation by Ras, Rho, and Rab Small GTPases Experimental Biology and Medicine (Maywood, N.J.). Nov, 2007 | Pubmed ID: 17959838 Molecular Determinants of PI(4,5)P2 and PI(3,4,5)P3 Regulation of the Epithelial Na+ Channel The Journal of General Physiology. Oct, 2007 | Pubmed ID: 17893193 Subunit-dependent Cadmium and Nickel Inhibition of Acid-sensing Ion Channels Developmental Neurobiology. Jan, 2007 | Pubmed ID: 17443775 Acute Regulation of the Epithelial Na+ Channel by Phosphatidylinositide 3-OH Kinase Signaling in Native Collecting Duct Principal Cells Journal of the American Society of Nephrology : JASN. Jun, 2007 | Pubmed ID: 17442787 Quantifying RhoA Facilitated Trafficking of the Epithelial Na+ Channel Toward the Plasma Membrane with Total Internal Reflection Fluorescence-fluorescence Recovery After Photobleaching The Journal of Biological Chemistry. May, 2007 | Pubmed ID: 17376773 Binding and Direct Activation of the Epithelial Na+ Channel (ENaC) by Phosphatidylinositides The Journal of Physiology. Apr, 2007 | Pubmed ID: 17272344 Functional Reconstitution of the Human Epithelial Na+ Channel in a Mammalian Expression System Methods in Molecular Biology (Clifton, N.J.). 2006 | Pubmed ID: 16929934 Magnesium Permeation Through Mechanosensitive Channels: Single-current Measurements Cell Research. Aug, 2006 | Pubmed ID: 16871269 Rapid Translocation and Insertion of the Epithelial Na+ Channel in Response to RhoA Signaling The Journal of Biological Chemistry. Sep, 2006 | Pubmed ID: 16829523 Regulation of the Epithelial Na+ Channel (ENaC) by Phosphatidylinositides American Journal of Physiology. Renal Physiology. May, 2006 | Pubmed ID: 16601296 Regulation of Epithelial Na+ Channel Activity by Conserved Serine/threonine Switches Within Sorting Signals The Journal of Biological Chemistry. Nov, 2005 | Pubmed ID: 16203727 Identification of a Functional Phosphatidylinositol 3,4,5-trisphosphate Binding Site in the Epithelial Na+ Channel The Journal of Biological Chemistry. Nov, 2005 | Pubmed ID: 16154997 Ras Couples Phosphoinositide 3-OH Kinase to the Epithelial Na+ Channel Biochimica Et Biophysica Acta. May, 2005 | Pubmed ID: 15893513 Actin Cytoskeleton Disassembly Affects Conductive Properties of Stretch-activated Cation Channels in Leukaemia Cells Biochimica Et Biophysica Acta. May, 2005 | Pubmed ID: 15842999 Epithelial Na+ Channel Subunit Stoichiometry Biophysical Journal. Jun, 2005 | Pubmed ID: 15821171 Rho Small GTPases Activate the Epithelial Na(+) Channel The Journal of Biological Chemistry. Nov, 2004 | Pubmed ID: 15448132 Ras Activates the Epithelial Na(+) Channel Through Phosphoinositide 3-OH Kinase Signaling The Journal of Biological Chemistry. Sep, 2004 | Pubmed ID: 15215250 Fluorescence Resonance Energy Transfer Analysis of Subunit Stoichiometry of the Epithelial Na+ Channel The Journal of Biological Chemistry. Jun, 2004 | Pubmed ID: 15096495 एंजाइमी biosensors के उपयोग अंतर्जात एटीपी या एच यों Oleg Palygin1, Vladislav Levchenko1, Louise C. Evans1, Gregory Blass1, Allen W. Cowley Jr.1, Alexander Staruschenko1 1Department of Physiology, Medical College of Wisconsin Biology पैच दबाना और लाइव प्रतिदीप्ति माइक्रोस्कोपी को लागू हौसले से पृथक PKD उपकला के कार्यात्मक संपत्तियों को मॉनिटर करने के लिए Tengis S. Pavlov1, Daria V. Ilatovskaya1, Oleg Palygin1, Vladislav Levchenko1, Oleh Pochynyuk2, Alexander Staruschenko1 1Department of Physiology, Medical College of Wisconsin, 2Department of Integrative Biology & Pharmacology, University of Texas Health Science Center at Houston JoVE 53035 Biology हौसले से अलग glomeruli की Podocytes में एकल चैनल विश्लेषण और कैल्शियम इमेजिंग Daria V. Ilatovskaya1, Oleg Palygin1, Vladislav Levchenko1, Alexander Staruschenko1 1Department of Physiology, Medical College of Wisconsin Biology Intracellular सीए की दो photon इमेजिंग Bradley T. Endres1,2, Alexander Staruschenko1, Marie Schulte4, Aron M. Geurts1,2,3, Oleg Palygin1 1Departments of Physiology, Medical College of Wisconsin, 2Human and Molecular Genetics Center, Medical College of Wisconsin, 3Cardiovascular Center, Medical College of Wisconsin, 4Blood Research Institute of Wisconsin Biology
एंजाइमी biosensors के उपयोग अंतर्जात एटीपी या एच यों Oleg Palygin1, Vladislav Levchenko1, Louise C. Evans1, Gregory Blass1, Allen W. Cowley Jr.1, Alexander Staruschenko1 1Department of Physiology, Medical College of Wisconsin Biology
पैच दबाना और लाइव प्रतिदीप्ति माइक्रोस्कोपी को लागू हौसले से पृथक PKD उपकला के कार्यात्मक संपत्तियों को मॉनिटर करने के लिए Tengis S. Pavlov1, Daria V. Ilatovskaya1, Oleg Palygin1, Vladislav Levchenko1, Oleh Pochynyuk2, Alexander Staruschenko1 1Department of Physiology, Medical College of Wisconsin, 2Department of Integrative Biology & Pharmacology, University of Texas Health Science Center at Houston JoVE 53035 Biology
हौसले से अलग glomeruli की Podocytes में एकल चैनल विश्लेषण और कैल्शियम इमेजिंग Daria V. Ilatovskaya1, Oleg Palygin1, Vladislav Levchenko1, Alexander Staruschenko1 1Department of Physiology, Medical College of Wisconsin Biology
Intracellular सीए की दो photon इमेजिंग Bradley T. Endres1,2, Alexander Staruschenko1, Marie Schulte4, Aron M. Geurts1,2,3, Oleg Palygin1 1Departments of Physiology, Medical College of Wisconsin, 2Human and Molecular Genetics Center, Medical College of Wisconsin, 3Cardiovascular Center, Medical College of Wisconsin, 4Blood Research Institute of Wisconsin Biology
