Alexander Thielen Max Planck Institute for Informatics Biography Publications Institution JoVE Articles Alexander Thielen has not added a biography. If you are Alexander Thielen and would like to personalize this page please email our Author Liaison for assistance. Publications Geno2pheno[454]: A Web Server for the Prediction of HIV-1 Coreceptor Usage from Next-Generation Sequencing Data Intervirology. 2012 | Pubmed ID: 22286879 HIV-GRADE: A Publicly Available, Rules-Based Drug Resistance Interpretation Algorithm Integrating Bioinformatic Knowledge Intervirology. 2012 | Pubmed ID: 22286877 APOBEC3G/F As One Possible Driving Force for Co-receptor Switch of the Human Immunodeficiency Virus-1 Medical Microbiology and Immunology. Feb, 2012 | Pubmed ID: 21573951 Deep V3 Sequencing for HIV Type 1 Tropism in Treatment-naive Patients: a Reanalysis of the MERIT Trial of Maraviroc Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America. Oct, 2011 | Pubmed ID: 21890778 HIV-1 Mutational Pathways Under Multidrug Therapy AIDS Research and Therapy. 2011 | Pubmed ID: 21794106 High Concordance Between the Position-specific Scoring Matrix and Geno2pheno Algorithms for Genotypic Interpretation of HIV-1 Tropism: V3 Length As the Major Cause of Disagreement Journal of Clinical Microbiology. Sep, 2011 | Pubmed ID: 21734029 Added Value of Deep Sequencing Relative to Population Sequencing in Heavily Pre-treated HIV-1-infected Subjects PloS One. 2011 | Pubmed ID: 21602929 Genotypic Tropism Testing by Massively Parallel Sequencing: Qualitative and Quantitative Analysis BMC Medical Informatics and Decision Making. 2011 | Pubmed ID: 21569501 Mutations in Gp41 Are Correlated with Coreceptor Tropism but Do Not Improve Prediction Methods Substantially Antiviral Therapy. 2011 | Pubmed ID: 21555814 Deep Sequencing to Infer HIV-1 Co-receptor Usage: Application to Three Clinical Trials of Maraviroc in Treatment-experienced Patients The Journal of Infectious Diseases. Jan, 2011 | Pubmed ID: 21288824 In-depth Analysis of G-to-A Hypermutation Rate in HIV-1 Env DNA Induced by Endogenous APOBEC3 Proteins Using Massively Parallel Sequencing Journal of Virological Methods. Feb, 2011 | Pubmed ID: 21111003 Dynamic Escape of Pre-existing Raltegravir-resistant HIV-1 from Raltegravir Selection Pressure Antiviral Research. Dec, 2010 | Pubmed ID: 20883724 Improved Prediction of HIVâ€1 Coreceptor Usage with Sequence Information from the Second Hypervariable Loop of Gp120 The Journal of Infectious Diseases. Nov, 2010 | Pubmed ID: 20874088 Population-based V3 Genotypic Tropism Assay: a Retrospective Analysis Using Screening Samples from the A4001029 and MOTIVATE Studies AIDS (London, England). Oct, 2010 | Pubmed ID: 20736814 Improved Detection of CXCR4-using HIV by V3 Genotyping: Application of Population-based and "deep" Sequencing to Plasma RNA and Proviral DNA Journal of Acquired Immune Deficiency Syndromes (1999). Aug, 2010 | Pubmed ID: 20512044 Decreased HIV Diversity After Allogeneic Stem Cell Transplantation of an HIV-1 Infected Patient: a Case Report Virology Journal. 2010 | Pubmed ID: 20210988 V3 Loop Sequence Space Analysis Suggests Different Evolutionary Patterns of CCR5- and CXCR4-tropic HIV PloS One. 2009 | Pubmed ID: 19816596 Bioinformatics Prediction of HIV Coreceptor Usage Nature Biotechnology. Dec, 2007 | Pubmed ID: 18066037 एचआईवी 1 अनुक्रम विश्लेषण द्वारा Coreceptor का उपयोग (tropism) की भविष्यवाणी एक genotypic दृष्टिकोण का उपयोग Saleta Sierra1, Rolf Kaiser1, Nadine Lübke1, Alexander Thielen2, Eugen Schuelter1, Eva Heger1, Martin Däumer3, Stefan Reuter4, Stefan Esser5, Gerd Fätkenheuer6, Herbert Pfister1, Mark Oette7, Thomas Lengauer2 1Institute of Virology, University of Cologne, 2Max Planck Institute for Informatics, 3Institute for Immune genetics, 4Department of Gastroenterology, Hepatology and Infectiology, University of Duesseldorf, 5Department of Dermatology, University of Essen, 6Department of Internal Medicine, University of Cologne, 7Augustinerinnen Hospital JoVE 3264 Immunology and Infection
एचआईवी 1 अनुक्रम विश्लेषण द्वारा Coreceptor का उपयोग (tropism) की भविष्यवाणी एक genotypic दृष्टिकोण का उपयोग Saleta Sierra1, Rolf Kaiser1, Nadine Lübke1, Alexander Thielen2, Eugen Schuelter1, Eva Heger1, Martin Däumer3, Stefan Reuter4, Stefan Esser5, Gerd Fätkenheuer6, Herbert Pfister1, Mark Oette7, Thomas Lengauer2 1Institute of Virology, University of Cologne, 2Max Planck Institute for Informatics, 3Institute for Immune genetics, 4Department of Gastroenterology, Hepatology and Infectiology, University of Duesseldorf, 5Department of Dermatology, University of Essen, 6Department of Internal Medicine, University of Cologne, 7Augustinerinnen Hospital JoVE 3264 Immunology and Infection
