Alexey Kostikov

Publications

• Radiosynthesis of the Diastereomerically Pure (E)-[ C]ABP688
  Journal of Labelled Compounds & Radiopharmaceuticals. Aug, 2019  |   Pubmed ID: 31418468
• Radioligands for Tropomyosin Receptor Kinase (Trk) Positron Emission Tomography Imaging
  Pharmaceuticals (Basel, Switzerland). Jan, 2019  |   Pubmed ID: 30609832
• Effect of (Z)-isomer Content on [C]ABP688 Binding Potential in Humans
  European Journal of Nuclear Medicine and Molecular Imaging. May, 2019  |   Pubmed ID: 30607444
• A Simplified Radiosynthesis of [ F]MK-6240 for Tau PET Imaging
  Journal of Labelled Compounds & Radiopharmaceuticals. 02, 2019  |   Pubmed ID: 30426529
• Identification of [F]TRACK, a Fluorine-18-Labeled Tropomyosin Receptor Kinase (Trk) Inhibitor for PET Imaging
  Journal of Medicinal Chemistry. 02, 2018  |   Pubmed ID: 29257860
• [F]ODIBO: a Prosthetic Group for Bioorthogonal Radiolabeling of Macromolecules Via Strain-promoted Alkyne-azide Cycloaddition
  Organic & Biomolecular Chemistry. 01, 2018  |   Pubmed ID: 29170778
• Multimodal Imaging in Rat Model Recapitulates Alzheimer's Disease Biomarkers Abnormalities
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. 12, 2017  |   Pubmed ID: 29097597
• Highly Efficient Solid Phase Supported Radiosynthesis of [ C]PiB Using TC18 Cartridge As a "3-in-1" Production Entity
  Journal of Labelled Compounds & Radiopharmaceuticals. 12, 2017  |   Pubmed ID: 28981146
• A Kinome-Wide Selective Radiolabeled TrkB/C Inhibitor for in Vitro and in Vivo Neuroimaging: Synthesis, Preclinical Evaluation, and First-in-Human
  Journal of Medicinal Chemistry. 08, 2017  |   Pubmed ID: 28696690
• Development of "[C]kits" for a Fast, Efficient and Reliable Production of Carbon-11 Labeled Radiopharmaceuticals for Positron Emission Tomography
  Applied Radiation and Isotopes : Including Data, Instrumentation and Methods for Use in Agriculture, Industry and Medicine. Mar, 2017  |   Pubmed ID: 28038410
• Towards the PET Radiotracer for P75 Neurotrophin Receptor: [(11)C]LM11A-24 Shows Biological Activity in Vitro, but Unfavorable Ex Vivo and in Vivo Profile
  Bioorganic & Medicinal Chemistry. 10, 2016  |   Pubmed ID: 27567078
• Which Aspects of Stroke Do Animal Models Capture? A Multitracer Micro-PET Study of Focal Ischemia with Endothelin-1
  Cerebrovascular Diseases (Basel, Switzerland). 2016  |   Pubmed ID: 26752046
• In Vivo Characterization of Metabotropic Glutamate Receptor Type 5 Abnormalities in Behavioral Variant FTD
  Brain Structure & Function. Apr, 2016  |   Pubmed ID: 25596865
• In Vivo Evaluation of ¹⁸F-SiFAlin-Modified TATE: A Potential Challenge for ⁶⁸Ga-DOTATATE, the Clinical Gold Standard for Somatostatin Receptor Imaging with PET
  Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Jul, 2015  |   Pubmed ID: 25977461
• Syntheses and Evaluation of Carbon-11- and Fluorine-18-radiolabeled Pan-tropomyosin Receptor Kinase (Trk) Inhibitors: Exploration of the 4-aza-2-oxindole Scaffold As Trk PET Imaging Agents
  ACS Chemical Neuroscience. Feb, 2015  |   Pubmed ID: 25350780
• ¹⁸F-labeled Silicon-based Fluoride Acceptors: Potential Opportunities for Novel Positron Emitting Radiopharmaceuticals
  BioMed Research International. 2014  |   Pubmed ID: 25157357
• Cholinergic Depletion in Alzheimer's Disease Shown by [ (18) F]FEOBV Autoradiography
  International Journal of Molecular Imaging. 2013  |   Pubmed ID: 24324884
• Concordance Between in Vivo and Postmortem Measurements of Cholinergic Denervation in Rats Using PET with [18F]FEOBV and Choline Acetyltransferase Immunochemistry
  EJNMMI Research. Oct, 2013  |   Pubmed ID: 24103360
• GABAA Receptors Predict Aversion-related Brain Responses: an FMRI-PET Investigation in Healthy Humans
  Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. Jul, 2013  |   Pubmed ID: 23389691
• Synthesis of [(18)F]SiFB: a Prosthetic Group for Direct Protein Radiolabeling for Application in Positron Emission Tomography
  Nature Protocols. Nov, 2012  |   Pubmed ID: 23037310
• Oxalic Acid Supported Si-18F-radiofluorination: One-step Radiosynthesis of N-succinimidyl 3-(di-tert-butyl[18F]fluorosilyl)benzoate ([18F]SiFB) for Protein Labeling
  Bioconjugate Chemistry. Jan, 2012  |   Pubmed ID: 22148255
• T-Bu2SiF-derivatized D2-receptor Ligands: the First SiFA-containing Small Molecule Radiotracers for Target-specific PET-imaging
  Molecules (Basel, Switzerland). Sep, 2011  |   Pubmed ID: 21892125
• Where In-vivo Imaging Meets Cytoarchitectonics: the Relationship Between Cortical Thickness and Neuronal Density Measured with High-resolution [18F]flumazenil-PET
  NeuroImage. Jun, 2011  |   Pubmed ID: 21073964