Alfons Lawen Department of Biochemistry and Molecular Biology, School of Biomedical Sciences Monash University Biography Publications Institution JoVE Articles Alfons Lawen has not added a biography. If you are Alfons Lawen and would like to personalize this page please email our Author Liaison for assistance. Publications Mammalian Iron Homeostasis in Health and Disease: Uptake, Storage, Transport, and Molecular Mechanisms of Action Antioxidants & Redox Signaling. Jun, 2013 | Pubmed ID: 23199217 The Glutamate Aspartate Transporter (GLAST) Mediates L-glutamate-stimulated Ascorbate-release Via Swelling-activated Anion Channels in Cultured Neonatal Rodent Astrocytes Cell Biochemistry and Biophysics. Mar, 2013 | Pubmed ID: 22886112 Characterization of the N-methyltransferase Activities of the Multifunctional Polypeptide Cyclosporin Synthetase Chemistry & Biology. Apr, 2011 | Pubmed ID: 21513883 Two Routes of Iron Accumulation in Astrocytes: Ascorbate-dependent Ferrous Iron Uptake Via the Divalent Metal Transporter (DMT1) Plus an Independent Route for Ferric Iron The Biochemical Journal. Nov, 2010 | Pubmed ID: 20819077 Neurones Express Glutamine Synthetase when Deprived of Glutamine or Interaction with Astrocytes Journal of Neurochemistry. Sep, 2010 | Pubmed ID: 20557426 A Role for Na+/H+ Exchangers and Intracellular PH in Regulating Vitamin C-driven Electron Transport Across the Plasma Membrane The Biochemical Journal. Jun, 2010 | Pubmed ID: 20307259 Voltage-dependent Anion-selective Channel (VDAC) in the Plasma Membrane FEBS Letters. May, 2010 | Pubmed ID: 20184885 Inhibition of Abeta Aggregation and Neurotoxicity by the 39-kDa Receptor-associated Protein Journal of Neurochemistry. Mar, 2010 | Pubmed ID: 20002523 Ascorbate and Plasma Membrane Electron Transport--enzymes Vs Efflux Free Radical Biology & Medicine. Sep, 2009 | Pubmed ID: 19501649 Targeting Mitochondrial Permeability in Cancer Drug Development Molecular Nutrition & Food Research. Jan, 2009 | Pubmed ID: 19035550 Transplasma Membrane Electron Transport Comes in Two Flavors BioFactors (Oxford, England). 2008 | Pubmed ID: 19734120 Non-transferrin Iron Reduction and Uptake Are Regulated by Transmembrane Ascorbate Cycling in K562 Cells The Journal of Biological Chemistry. May, 2008 | Pubmed ID: 18347019 A Highly Sensitive Colorimetric Microplate Ferrocyanide Assay Applied to Ascorbate-stimulated Transplasma Membrane Ferricyanide Reduction and Mitochondrial Succinate Oxidation Analytical Biochemistry. Feb, 2008 | Pubmed ID: 17949676 Another Piece of the Puzzle of Apoptotic Cytochrome C Release Molecular Microbiology. Nov, 2007 | Pubmed ID: 17887962 Mitocans: Mitochondrial Targeted Anti-cancer Drugs As Improved Therapies and Related Patent Documents Recent Patents on Anti-cancer Drug Discovery. Nov, 2006 | Pubmed ID: 18221044 An Improved Purification Procedure for Cyclosporin Synthetase Protein Expression and Purification. Feb, 2006 | Pubmed ID: 16139518 Voltage-dependent Anion-selective Channel 1 (VDAC1)--a Mitochondrial Protein, Rediscovered As a Novel Enzyme in the Plasma Membrane The International Journal of Biochemistry & Cell Biology. Feb, 2005 | Pubmed ID: 15474974 Plasma Membrane NADH-oxidoreductase in Cells Carrying Mitochondrial DNA G11778A Mutation and in Cells Devoid of Mitochondrial DNA (rho0) BioFactors (Oxford, England). 2004 | Pubmed ID: 15706055 Characterization of VDAC1 As a Plasma Membrane NADH-oxidoreductase BioFactors (Oxford, England). 2004 | Pubmed ID: 15630200 VDAC1 is a Transplasma Membrane NADH-ferricyanide Reductase The Journal of Biological Chemistry. Feb, 2004 | Pubmed ID: 14573604 Non-ribosomal Peptide Synthetases As Technological Platforms for the Synthesis of Highly Modified Peptide Bioeffectors--Cyclosporin Synthetase As a Complex Example Biotechnology Annual Review. 2003 | Pubmed ID: 14650927 Bioethics Needs a Distinct Voice if It is to Aid Science Nature. Oct, 2003 | Pubmed ID: 14574381 Novel Effects on Memory Observed Following Unilateral Intracranial Administration of Okadaic Acid, Cyclosporin A, FK506 and [MeVal4]CyA Brain Research. Oct, 2003 | Pubmed ID: 14519526 Apoptosis-an Introduction BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology. Sep, 2003 | Pubmed ID: 12938178 Involvement of Reactive Oxygen Species in Capsaicinoid-induced Apoptosis in Transformed Cells Free Radical Research. Jun, 2003 | Pubmed ID: 12868488 New Functions of an Old Protein: the Eukaryotic Porin or Voltage Dependent Anion Selective Channel (VDAC) The Italian Journal of Biochemistry. Mar, 2003 | Pubmed ID: 12833633 Photoaffinity Labeling of the N-methyltransferase Domains of Cyclosporin Synthetase Photochemistry and Photobiology. Feb, 2003 | Pubmed ID: 12785050 Transplasma Membrane Electron Transport: Enzymes Involved and Biological Function Redox Report : Communications in Free Radical Research. 2003 | Pubmed ID: 12631439 Mapping and Molecular Modeling of S-adenosyl-L-methionine Binding Sites in N-methyltransferase Domains of the Multifunctional Polypeptide Cyclosporin Synthetase The Journal of Biological Chemistry. Jan, 2003 | Pubmed ID: 12399454 Cyclosporin A, FK506 and Rapamycin Produce Multiple, Temporally Distinct, Effects on Memory Following Single-trial, Passive Avoidance Training in the Chick Brain Research. Feb, 2002 | Pubmed ID: 11821011 Een snelle en specifieke Microplate Assay voor de bepaling van de intra-en extracellulaire ascorbaat in gekweekte cellen Darius J. R. Lane1, Alfons Lawen2 1Molecular Pharmacology and Pathology Program, Department of Pathology & Bosch Institute, University of Sydney, 2Department of Biochemistry and Molecular Biology, School of Biomedical Sciences, Monash University JoVE 51322 Biology
Een snelle en specifieke Microplate Assay voor de bepaling van de intra-en extracellulaire ascorbaat in gekweekte cellen Darius J. R. Lane1, Alfons Lawen2 1Molecular Pharmacology and Pathology Program, Department of Pathology & Bosch Institute, University of Sydney, 2Department of Biochemistry and Molecular Biology, School of Biomedical Sciences, Monash University JoVE 51322 Biology