Alfonso Martinez Arias

Publications

• FGF/MAPK Signaling Sets the Switching Threshold of a Bistable Circuit Controlling Cell Fate Decisions in ES Cells
  Development (Cambridge, England). Oct, 2015  |   Pubmed ID: 26511924
• A Loss-of-function and H2B-Venus Transcriptional Reporter Allele for Gata6 in Mice
  BMC Developmental Biology. 2015  |   Pubmed ID: 26498761
• Inhibition of β-catenin-TCF1 Interaction Delays Differentiation of Mouse Embryonic Stem Cells
  The Journal of Cell Biology. Oct, 2015  |   Pubmed ID: 26459597
• Wnt/ß-catenin Signalling and the Dynamics of Fate Decisions in Early Mouse Embryos and Embryonic Stem (ES) Cells
  Seminars in Cell & Developmental Biology. Aug, 2015  |   Pubmed ID: 26321498
• Dynamic Proteomic Profiling of Extra-Embryonic Endoderm Differentiation in Mouse Embryonic Stem Cells
  Stem Cells (Dayton, Ohio). Sep, 2015  |   Pubmed ID: 26059426
• Cell Dynamics and Gene Expression Control in Tissue Homeostasis and Development
  Molecular Systems Biology. Jan, 2015  |   Pubmed ID: 25716053
• Wnt/β-catenin and FGF Signalling Direct the Specification and Maintenance of a Neuromesodermal Axial Progenitor in Ensembles of Mouse Embryonic Stem Cells
  Development (Cambridge, England). Nov, 2014  |   Pubmed ID: 25371361
• Symmetry Breaking, Germ Layer Specification and Axial Organisation in Aggregates of Mouse Embryonic Stem Cells
  Development (Cambridge, England). Nov, 2014  |   Pubmed ID: 25371360
• Brachyury Cooperates with Wnt/β-catenin Signalling to Elicit Primitive-streak-like Behaviour in Differentiating Mouse Embryonic Stem Cells
  BMC Biology. 2014  |   Pubmed ID: 25115237
• An Interplay Between Extracellular Signalling and the Dynamics of the Exit from Pluripotency Drives Cell Fate Decisions in Mouse ES Cells
  Biology Open. 2014  |   Pubmed ID: 24950969
• Determining Protein Subcellular Localization in Mammalian Cell Culture with Biochemical Fractionation and ITRAQ 8-plex Quantification
  Methods in Molecular Biology (Clifton, N.J.). 2014  |   Pubmed ID: 24791987
• Contractile and Mechanical Properties of Epithelia with Perturbed Actomyosin Dynamics
  PloS One. 2014  |   Pubmed ID: 24759936
• Single Cell Lineage Analysis of Mouse Embryonic Stem Cells at the Exit from Pluripotency
  Biology Open. 2013  |   Pubmed ID: 24167715
• A Competitive Protein Interaction Network Buffers Oct4-mediated Differentiation to Promote Pluripotency in Embryonic Stem Cells
  Molecular Systems Biology. 2013  |   Pubmed ID: 24104477
• A Molecular Basis for Developmental Plasticity in Early Mammalian Embryos
  Development (Cambridge, England). Sep, 2013  |   Pubmed ID: 23942513
• A Membrane-associated β-catenin/Oct4 Complex Correlates with Ground-state Pluripotency in Mouse Embryonic Stem Cells
  Development (Cambridge, England). Mar, 2013  |   Pubmed ID: 23444350
• Activation of Notch in Lgd Mutant Cells Requires the Fusion of Late Endosomes with the Lysosome
  Journal of Cell Science. Jan, 2013  |   Pubmed ID: 23178945
• Interactions Between the Amnioserosa and the Epidermis Revealed by the Function of the U-shaped Gene
  Biology Open. Apr, 2012  |   Pubmed ID: 23213425
• Towards a Statistical Mechanics of Cell Fate Decisions
  Current Opinion in Genetics & Development. Dec, 2012  |   Pubmed ID: 23200114
• Chromatin Decondensation and Nuclear Softening Accompany Nanog Downregulation in Embryonic Stem Cells
  Biophysical Journal. Nov, 2012  |   Pubmed ID: 23200040
• Cell Signalling Regulates Dynamics of Nanog Distribution in Embryonic Stem Cell Populations
  Journal of the Royal Society, Interface / the Royal Society. Oct, 2012  |   Pubmed ID: 23054952
• Correlations Between the Levels of Oct4 and Nanog As a Signature for Naïve Pluripotency in Mouse Embryonic Stem Cells
  Stem Cells (Dayton, Ohio). Dec, 2012  |   Pubmed ID: 22969005
• Drosophila Midgut Homeostasis Involves Neutral Competition Between Symmetrically Dividing Intestinal Stem Cells
  The EMBO Journal. May, 2012  |   Pubmed ID: 22522699
• Interplay Between Gene Expression Noise and Regulatory Network Architecture
  Trends in Genetics : TIG. May, 2012  |   Pubmed ID: 22365642
• The Structure of Wntch Signalling and the Resolution of Transition States in Development
  Seminars in Cell & Developmental Biology. Jun, 2012  |   Pubmed ID: 22326376
• Dissecting Ensemble Networks in ES Cell Populations Reveals Micro-heterogeneity Underlying Pluripotency
  Molecular BioSystems. Mar, 2012  |   Pubmed ID: 22222461
• Wnt-Notch Signalling: an Integrated Mechanism Regulating Transitions Between Cell States
  BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology. Feb, 2012  |   Pubmed ID: 22215536
• Patterned Cell Adhesion Associated with Tissue Deformations During Dorsal Closure in Drosophila
  PloS One. 2011  |   Pubmed ID: 22076130
• Gene Expression Heterogeneities in Embryonic Stem Cell Populations: Origin and Function
  Current Opinion in Cell Biology. Dec, 2011  |   Pubmed ID: 21982544
• Probing the Druggability of Protein-protein Interactions: Targeting the Notch1 Receptor Ankyrin Domain Using a Fragment-based Approach
  Biochemical Society Transactions. Oct, 2011  |   Pubmed ID: 21936810
• Endocytic and Recycling Endosomes Modulate Cell Shape Changes and Tissue Behaviour During Morphogenesis in Drosophila
  PloS One. 2011  |   Pubmed ID: 21533196
• Modulation of the Ligand-independent Traffic of Notch by Axin and Apc Contributes to the Activation of Armadillo in Drosophila
  Development (Cambridge, England). Apr, 2011  |   Pubmed ID: 21389052
• Cytoskeletal Dynamics and Supracellular Organisation of Cell Shape Fluctuations During Dorsal Closure
  Development (Cambridge, England). Aug, 2010  |   Pubmed ID: 20663818
• Wingless Modulates the Ligand Independent Traffic of Notch Through Dishevelled
  Fly. Jul-Sep, 2010  |   Pubmed ID: 20495361
• A Role of Receptor Notch in Ligand Cis-inhibition in Drosophila
  Current Biology : CB. Mar, 2010  |   Pubmed ID: 20226663
• Mechanisms of Ligand-mediated Inhibition in Notch Signaling Activity in Drosophila
  Developmental Dynamics : an Official Publication of the American Association of Anatomists. Mar, 2010  |   Pubmed ID: 20063416
• A Perspective on the Development of Genetics in Spain During the XX Century
  The International Journal of Developmental Biology. 2009  |   Pubmed ID: 19924624
• The Structural and Functional Determinants of the Axin and Dishevelled DIX Domains
  BMC Structural Biology. 2009  |   Pubmed ID: 19909509
• Ligand-independent Traffic of Notch Buffers Activated Armadillo in Drosophila
  PLoS Biology. Aug, 2009  |   Pubmed ID: 19668359
• Origin and Function of Fluctuations in Cell Behaviour and the Emergence of Patterns
  Seminars in Cell & Developmental Biology. Sep, 2009  |   Pubmed ID: 19665568
• Regulated Fluctuations in Nanog Expression Mediate Cell Fate Decisions in Embryonic Stem Cells
  PLoS Biology. Jul, 2009  |   Pubmed ID: 19582141
• Mechanical Control of Global Cell Behaviour During Dorsal Closure in Drosophila
  Development (Cambridge, England). Jun, 2009  |   Pubmed ID: 19403661
• Getting the Measure of Positional Information
  PLoS Biology. Mar, 2009  |   Pubmed ID: 19338391
• Mapping Organelle Proteins and Protein Complexes in Drosophila Melanogaster
  Journal of Proteome Research. Jun, 2009  |   Pubmed ID: 19317464
• Flamingo Regulates Epiboly and Convergence/extension Movements Through Cell Cohesive and Signalling Functions During Zebrafish Gastrulation
  Development (Cambridge, England). Feb, 2009  |   Pubmed ID: 19091770
• The Drosophila STIM1 Orthologue, DSTIM, Has Roles in Cell Fate Specification and Tissue Patterning
  BMC Developmental Biology. 2008  |   Pubmed ID: 18950512
• Wingless Signalling Alters the Levels, Subcellular Distribution and Dynamics of Armadillo and E-cadherin in Third Instar Larval Wing Imaginal Discs
  PloS One. 2008  |   Pubmed ID: 18682750
• Drosophila Melanogaster and the Development of Biology in the 20th Century
  Methods in Molecular Biology (Clifton, N.J.). 2008  |   Pubmed ID: 18641938
• Wnt/Notch Signalling and Information Processing During Development
  Development (Cambridge, England). Feb, 2008  |   Pubmed ID: 18192283
• Dpp Signalling Orchestrates Dorsal Closure by Regulating Cell Shape Changes Both in the Amnioserosa and in the Epidermis
  Mechanisms of Development. Nov-Dec, 2007  |   Pubmed ID: 17950580
• Requirements for Adherens Junction Components in the Interaction Between Epithelial Tissues During Dorsal Closure in Drosophila
  Journal of Cell Science. Sep, 2007  |   Pubmed ID: 17878238
• Cell and Molecular Biology of Notch
  The Journal of Endocrinology. Sep, 2007  |   Pubmed ID: 17761886
• Notch Signaling Pathway
  Science's STKE : Signal Transduction Knowledge Environment. Dec, 2006  |   Pubmed ID: 17148788
• Notch, a Universal Arbiter of Cell Fate Decisions
  Science (New York, N.Y.). Dec, 2006  |   Pubmed ID: 17138893
• High-throughput Localization of Organelle Proteins by Mass Spectrometry: a Quantum Leap for Cell Biology
  BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology. Aug, 2006  |   Pubmed ID: 16927390
• Notch Synergizes with Axin to Regulate the Activity of Armadillo in Drosophila
  Developmental Dynamics : an Official Publication of the American Association of Anatomists. Oct, 2006  |   Pubmed ID: 16881048
• Notch Receptor Encodes Two Structurally Separable Functions in Drosophila: a Genetic Analysis
  Developmental Dynamics : an Official Publication of the American Association of Anatomists. Apr, 2006  |   Pubmed ID: 16534797
• Filtering Transcriptional Noise During Development: Concepts and Mechanisms
  Nature Reviews. Genetics. Jan, 2006  |   Pubmed ID: 16369570
• Cell Signaling. Frizzled at the Cutting Edge of the Synapse
  Science (New York, N.Y.). Nov, 2005  |   Pubmed ID: 16311322
• High-resolution Crystal Structure of the Human Notch 1 Ankyrin Domain
  The Biochemical Journal. Nov, 2005  |   Pubmed ID: 16011479
• Notch Modulates Wnt Signalling by Associating with Armadillo/beta-catenin and Regulating Its Transcriptional Activity
  Development (Cambridge, England). Apr, 2005  |   Pubmed ID: 15772135
• Armadillo/beta-catenin-dependent Wnt Signalling is Required for the Polarisation of Epidermal Cells During Dorsal Closure in Drosophila
  Development (Cambridge, England). Jul, 2004  |   Pubmed ID: 15226252
• Building and Engineering Organisms: the Cellular Interface
  Mechanisms of Development. Nov, 2003  |   Pubmed ID: 14623433
• Wnts As Morphogens? The View from the Wing of Drosophila
  Nature Reviews. Molecular Cell Biology. Apr, 2003  |   Pubmed ID: 12671654
• Planar Polarity and Actin Dynamics in the Epidermis of Drosophila
  Nature Cell Biology. Dec, 2002  |   Pubmed ID: 12447392
• CSL-independent Notch Signalling: a Checkpoint in Cell Fate Decisions During Development?
  Current Opinion in Genetics & Development. Oct, 2002  |   Pubmed ID: 12200157
• A New Dawn for an Old Connection: Development Meets the Cell
  Trends in Cell Biology. Jul, 2002  |   Pubmed ID: 12185848
• Dynamic Analysis of Actin Cable Function During Drosophila Dorsal Closure
  Current Biology : CB. Jul, 2002  |   Pubmed ID: 12176336
• New Alleles of Notch Draw a Blueprint for Multifunctionality
  Trends in Genetics : TIG. Apr, 2002  |   Pubmed ID: 11932008
• The Antennapedia Gene is Required and Expressed in Parasegments 4 and 5 of the Drosophila Embryo
  The EMBO Journal. Jan, 1986  |   Pubmed ID: 16453662