Alicia Alonso Department of Medicine Weill Cornell Medical College Biography Publications Institution JoVE Articles Alicia Alonso has not added a biography. If you are Alicia Alonso and would like to personalize this page please email our Author Liaison for assistance. Publications Atomic Force Microscopy Characterization of Palmitoylceramide and Cholesterol Effects on Phospholipid Bilayers: a Topographic and Nanomechanical Study Langmuir : the ACS Journal of Surfaces and Colloids. Feb, 2015 | Pubmed ID: 25693914 Histones Cause Aggregation and Fusion of Lipid Vesicles Containing Phosphatidylinositol-4-phosphate Biophysical Journal. Feb, 2015 | Pubmed ID: 25692591 Fluorescent Polyene Ceramide Analogues As Membrane Probes Langmuir : the ACS Journal of Surfaces and Colloids. Feb, 2015 | Pubmed ID: 25658138 Biophysical Properties of Novel 1-deoxy-(dihydro)ceramides Occurring in Mammalian Cells Biophysical Journal. Dec, 2014 | Pubmed ID: 25517151 High-melting Lipid Mixtures and the Origin of Detergent-resistant Membranes Studied with Temperature-solubilization Diagrams Biophysical Journal. Dec, 2014 | Pubmed ID: 25517149 Biophysical Properties of Sphingosine, Ceramides and Other Simple Sphingolipids Biochemical Society Transactions. Oct, 2014 | Pubmed ID: 25233422 A Cholesterol Recognition Motif in Human Phospholipid Scramblase 1 Biophysical Journal. Sep, 2014 | Pubmed ID: 25229146 Membrane Permeabilization Induced by Sphingosine: Effect of Negatively Charged Lipids Biophysical Journal. Jun, 2014 | Pubmed ID: 24940775 Sphingosine Induces the Aggregation of Imine-containing Peroxidized Vesicles Biochimica Et Biophysica Acta. Aug, 2014 | Pubmed ID: 24802275 Membrane Binding of Human Phospholipid Scramblase 1 Cytoplasmic Domain Biochimica Et Biophysica Acta. Jul, 2014 | Pubmed ID: 24680654 Histones and DNA Compete for Binding Polyphosphoinositides in Bilayers Biophysical Journal. Mar, 2014 | Pubmed ID: 24606933 Lamellar Gel (lβ) Phases of Ternary Lipid Composition Containing Ceramide and Cholesterol Biophysical Journal. Feb, 2014 | Pubmed ID: 24507602 Lipid Bilayers Containing Sphingomyelins and Ceramides of Varying N-acyl Lengths: a Glimpse into Sphingolipid Complexity Biochimica Et Biophysica Acta. Jan, 2014 | Pubmed ID: 24144542 Membrane Binding and Insertion of the Predicted Transmembrane Domain of Human Scramblase 1 Biochimica Et Biophysica Acta. Jan, 2014 | Pubmed ID: 24099740 A Topical Microemulsion for the Prevention of Allergic Rhinitis Symptoms: Results of a Randomized, Controlled, Double-blind, Parallel Group, Multicentre, Multinational Clinical Trial (Nares Study) Allergy, Asthma, and Clinical Immunology : Official Journal of the Canadian Society of Allergy and Clinical Immunology. 2013 | Pubmed ID: 23981504 The Octamer is the Major Form of CENP-A Nucleosomes at Human Centromeres Nature Structural & Molecular Biology. Jun, 2013 | Pubmed ID: 23644596 The Onset of Triton X-100 Solubilization of Sphingomyelin/ceramide Bilayers: Effects of Temperature and Composition Chemistry and Physics of Lipids. Feb-Mar, 2013 | Pubmed ID: 23453949 Detergent Solubilization of Lipid Bilayers: a Balance of Driving Forces Trends in Biochemical Sciences. Feb, 2013 | Pubmed ID: 23290685 Recruitment of a Phospholipase C/sphingomyelinase into Non-lamellar Lipid Droplets During Hydrolysis of Lipid Bilayers Chemistry and Physics of Lipids. Jan, 2013 | Pubmed ID: 23253877 In Situ Synthesis of Fluorescent Membrane Lipids (ceramides) Using Click Chemistry Journal of Chemical Biology. Jul, 2012 | Pubmed ID: 23596500 Accumulated Bending Energy Elicits Neutral Sphingomyelinase Activity in Human Red Blood Cells Biophysical Journal. May, 2012 | Pubmed ID: 22824271 Lipid Bilayers in the Gel Phase Become Saturated by Triton X-100 at Lower Surfactant Concentrations Than Those in the Fluid Phase Biophysical Journal. Jun, 2012 | Pubmed ID: 22713566 Phospholipases C and Sphingomyelinases: Lipids As Substrates and Modulators of Enzyme Activity Progress in Lipid Research. Jul, 2012 | Pubmed ID: 22504350 Formation of Novel CENP-A Domains on Tandem Repetitive DNA and Across Chromosome Breakpoints on Human Chromosome 8q21 Neocentromeres Chromosoma. Dec, 2011 | Pubmed ID: 21826412 Unexpected Wide Substrate Specificity of C. Perfringens α-toxin Phospholipase C Biochimica Et Biophysica Acta. Oct, 2011 | Pubmed ID: 21704605 Imaging the Early Stages of Phospholipase C/sphingomyelinase Activity on Vesicles Containing Coexisting Ordered-disordered and Gel-fluid Domains Journal of Lipid Research. Apr, 2011 | Pubmed ID: 21252263 Multiple Phospholipid Substrates of Phospholipase C/sphingomyelinase HR2 from Pseudomonas Aeruginosa Chemistry and Physics of Lipids. Jan, 2011 | Pubmed ID: 21073866 Effects of Bilayer Composition and Physical Properties on the Phospholipase C and Sphingomyelinase Activities of Clostridium Perfringens α-toxin Biochimica Et Biophysica Acta. Jan, 2011 | Pubmed ID: 20727345 Cholesterol Displaces Palmitoylceramide from Its Tight Packing with Palmitoylsphingomyelin in the Absence of a Liquid-disordered Phase Biophysical Journal. Aug, 2010 | Pubmed ID: 20712995 Dihydrosphingomyelin Impairs HIV-1 Infection by Rigidifying Liquid-ordered Membrane Domains Chemistry & Biology. Jul, 2010 | Pubmed ID: 20659689 Quantitation of Cholesterol Incorporation into Extruded Lipid Bilayers Biochimica Et Biophysica Acta. Sep, 2010 | Pubmed ID: 20537979 A Paucity of Heterochromatin at Functional Human Neocentromeres Epigenetics & Chromatin. 2010 | Pubmed ID: 20210998 Detergent Effects on Membranes at Subsolubilizing Concentrations: Transmembrane Lipid Motion, Bilayer Permeabilization, and Vesicle Lysis/reassembly Are Independent Phenomena Langmuir : the ACS Journal of Surfaces and Colloids. May, 2010 | Pubmed ID: 20170131 Transbilayer (flip-flop) Lipid Motion and Lipid Scrambling in Membranes FEBS Letters. May, 2010 | Pubmed ID: 20043909 Electroformation of Giant Unilamellar Vesicles from Native Membranes and Organic Lipid Mixtures for the Study of Lipid Domains Under Physiological Ionic-strength Conditions Methods in Molecular Biology (Clifton, N.J.). 2010 | Pubmed ID: 20013393 End-products Diacylglycerol and Ceramide Modulate Membrane Fusion Induced by a Phospholipase C/sphingomyelinase from Pseudomonas Aeruginosa Biochimica Et Biophysica Acta. Jan, 2010 | Pubmed ID: 19891956 Coexistence of Immiscible Mixtures of Palmitoylsphingomyelin and Palmitoylceramide in Monolayers and Bilayers Biophysical Journal. Nov, 2009 | Pubmed ID: 19917225 Sphingosine-1-phosphate As an Amphipathic Metabolite: Its Properties in Aqueous and Membrane Environments Biophysical Journal. Sep, 2009 | Pubmed ID: 19720028 Phospholipase C and Sphingomyelinase Activities of the Clostridium Perfringens Alpha-toxin Chemistry and Physics of Lipids. May, 2009 | Pubmed ID: 19428363 Ceramide-induced Transbilayer (flip-flop) Lipid Movement in Membranes Methods in Molecular Biology (Clifton, N.J.). 2009 | Pubmed ID: 19160667 Calcium Inhibits Diacylglycerol Uptake by Serum Albumin Biochimica Et Biophysica Acta. Mar, 2009 | Pubmed ID: 19101500 Effects of Ceramide and Other Simple Sphingolipids on Membrane Lateral Structure Biochimica Et Biophysica Acta. Jan, 2009 | Pubmed ID: 18848519 Implication of Ceramide, Ceramide 1-phosphate and Sphingosine 1-phosphate in Tumorigenesis Translational Oncogenomics. 2008 | Pubmed ID: 21566746 Combination of the Anti-tumour Cell Ether Lipid Edelfosine with Sterols Abolishes Haemolytic Side Effects of the Drug Journal of Chemical Biology. Nov, 2008 | Pubmed ID: 19568801 Phase Diagrams of Lipid Mixtures Relevant to the Study of Membrane Rafts Biochimica Et Biophysica Acta. Nov-Dec, 2008 | Pubmed ID: 18952002 Ceramide-enriched Membrane Domains in Red Blood Cells and the Mechanism of Sphingomyelinase-induced Hot-cold Hemolysis Biochemistry. Oct, 2008 | Pubmed ID: 18826261 Cholesterol Displacement by Ceramide in Sphingomyelin-containing Liquid-ordered Domains, and Generation of Gel Regions in Giant Lipidic Vesicles FEBS Letters. Sep, 2008 | Pubmed ID: 18755187 Membrane Organization and Ionization Behavior of the Minor but Crucial Lipid Ceramide-1-phosphate Biophysical Journal. Jun, 2008 | Pubmed ID: 18296489 Lower Muscle Strength Gains in Older Men with Type 2 Diabetes After Resistance Training Journal of Diabetes and Its Complications. Mar-Apr, 2008 | Pubmed ID: 18280441 Giant Unilamellar Vesicles Electroformed from Native Membranes and Organic Lipid Mixtures Under Physiological Conditions Biophysical Journal. Nov, 2007 | Pubmed ID: 17704162 Triton X-100 Partitioning into Sphingomyelin Bilayers at Subsolubilizing Detergent Concentrations: Effect of Lipid Phase and a Comparison with Dipalmitoylphosphatidylcholine Biophysical Journal. Nov, 2007 | Pubmed ID: 17675347 Co-localization of CENP-C and CENP-H to Discontinuous Domains of CENP-A Chromatin at Human Neocentromeres Genome Biology. 2007 | Pubmed ID: 17651496 Leakage-free Membrane Fusion Induced by the Hydrolytic Activity of PlcHR(2), a Novel Phospholipase C/sphingomyelinase from Pseudomonas Aeruginosa Biochimica Et Biophysica Acta. Oct, 2007 | Pubmed ID: 17560896 Surface-active Properties of the Antitumour Ether Lipid 1-O-octadecyl-2-O-methyl-rac-glycero-3-phosphocholine (edelfosine) Biochimica Et Biophysica Acta. Jul, 2007 | Pubmed ID: 17543274 Biophysics of Sphingolipids I. Membrane Properties of Sphingosine, Ceramides and Other Simple Sphingolipids Biochimica Et Biophysica Acta. Dec, 2006 | Pubmed ID: 17070498 Independent Centromere Formation in a Capricious, Gene-free Domain of Chromosome 13q21 in Old World Monkeys and Pigs Genome Biology. 2006 | Pubmed ID: 17040560 Detergent Solubilization of Phosphatidylcholine Bilayers in the Fluid State: Influence of the Acyl Chain Structure Biochimica Et Biophysica Acta. Feb, 2006 | Pubmed ID: 16579963 Sphingosine Increases the Permeability of Model and Cell Membranes Biophysical Journal. Jun, 2006 | Pubmed ID: 16533839 Alkanes Are Not Innocuous Vehicles for Hydrophobic Reagents in Membrane Studies Chemistry and Physics of Lipids. Feb, 2006 | Pubmed ID: 16413518 Detergent-resistant, Ceramide-enriched Domains in Sphingomyelin/ceramide Bilayers Biophysical Journal. Feb, 2006 | Pubmed ID: 16284266 Modulation of PI-specific Phospholipase C by Membrane Curvature and Molecular Order Biochemistry. Aug, 2005 | Pubmed ID: 16114896 Molecular Associations and Surface-active Properties of Short- and Long-N-acyl Chain Ceramides Biochimica Et Biophysica Acta. Jun, 2005 | Pubmed ID: 15904658 Domain Formation in Sphingomyelin/cholesterol Mixed Membranes Studied by Spin-label Electron Spin Resonance Spectroscopy Biochemistry. Mar, 2005 | Pubmed ID: 15779918 Different Effects of Long- and Short-chain Ceramides on the Gel-fluid and Lamellar-hexagonal Transitions of Phospholipids: a Calorimetric, NMR, and X-ray Diffraction Study Biophysical Journal. May, 2005 | Pubmed ID: 15695626 Biophysics (and Sociology) of Ceramides Biochemical Society Symposium. 2005 | Pubmed ID: 15649141 Phosphorylation of Glycosyl-phosphatidylinositol by Phosphatidylinositol 3-kinase Changes Its Properties As a Substrate for Phospholipases FEBS Letters. Jan, 2005 | Pubmed ID: 15620691 Asymmetric Addition of Ceramides but Not Dihydroceramides Promotes Transbilayer (flip-flop) Lipid Motion in Membranes Biophysical Journal. Jan, 2005 | Pubmed ID: 15465865 Human Cytomegalovirus: Detection of Congenital and Perinatal Infection in Argentina BMC Pediatrics. Jun, 2004 | Pubmed ID: 15214967 Membrane Fusion Induced by the Catalytic Activity of a Phospholipase C/sphingomyelinase from Listeria Monocytogenes Biochemistry. Mar, 2004 | Pubmed ID: 15035639 Interaction of Phospholipases C and Sphingomyelinase with Liposomes Methods in Enzymology. 2003 | Pubmed ID: 14610804 Genomic Microarray Analysis Reveals Distinct Locations for the CENP-A Binding Domains in Three Human Chromosome 13q32 Neocentromeres Human Molecular Genetics. Oct, 2003 | Pubmed ID: 12928482 Sphingomyelinase Activity Causes Transbilayer Lipid Translocation in Model and Cell Membranes The Journal of Biological Chemistry. Sep, 2003 | Pubmed ID: 12855704 Surfactant Effects of Chlorpromazine and Imipramine on Lipid Bilayers Containing Sphingomyelin and Cholesterol Journal of Colloid and Interface Science. Dec, 2002 | Pubmed ID: 12573633 Sphingomyelinases: Enzymology and Membrane Activity FEBS Letters. Oct, 2002 | Pubmed ID: 12401200 Sphingomyelinase Cleavage of Sphingomyelin in Pure and Mixed Lipid Membranes. Influence of the Physical State of the Sphingolipid Chemistry and Physics of Lipids. Jan, 2002 | Pubmed ID: 11841822 Membrane Restructuring Via Ceramide Results in Enhanced Solute Efflux The Journal of Biological Chemistry. Apr, 2002 | Pubmed ID: 11796726 Enhanced réduit Représentation bisulfite séquençage pour l'évaluation de méthylation de l'ADN à la résolution de paires de base Francine E. Garrett-Bakelman*1, Caroline K. Sheridan*1, Thadeous J. Kacmarczyk1, Jennifer Ishii1, Doron Betel1,2, Alicia Alonso1, Christopher E. Mason3, Maria E. Figueroa4, Ari M. Melnick1 1Department of Medicine, Weill Cornell Medical College, 2Institute for Computational Biomedicine, Weill Cornell Medical College, 3Department of Physiology and Biophysics, Weill Cornell Medical College, 4Department of Pathology, University of Michigan Biology
Enhanced réduit Représentation bisulfite séquençage pour l'évaluation de méthylation de l'ADN à la résolution de paires de base Francine E. Garrett-Bakelman*1, Caroline K. Sheridan*1, Thadeous J. Kacmarczyk1, Jennifer Ishii1, Doron Betel1,2, Alicia Alonso1, Christopher E. Mason3, Maria E. Figueroa4, Ari M. Melnick1 1Department of Medicine, Weill Cornell Medical College, 2Institute for Computational Biomedicine, Weill Cornell Medical College, 3Department of Physiology and Biophysics, Weill Cornell Medical College, 4Department of Pathology, University of Michigan Biology
