Andre F. Palmer William G. Lowrie Department of Chemical and Biomolecular Engineering, College of Engineering The Ohio State University Biography Publications Institution JoVE Articles Andre F. Palmer has not added a biography. If you are Andre F. Palmer and would like to personalize this page please email our Author Liaison for assistance. Publications Tangential Flow Filtration Facilitated Fractionation and PEGylation of Low and High-molecular Weight Polymerized Hemoglobins and Their Biophysical Properties Biotechnology and Bioengineering. Oct, 2021 | Pubmed ID: 34672363 Biophysical Properties of Tense Quaternary State Polymerized Human Hemoglobins Bracketed Between 500 kDa and 0.2 μm in Size Biotechnology Progress. Oct, 2021 | Pubmed ID: 34626100 Magnetophoretic and Spectral Characterization of Oxyhemoglobin and Deoxyhemoglobin: Chemical Versus Enzymatic Processes PloS One. 2021 | Pubmed ID: 34478473 Polymerized Albumin Restores Impaired Hemodynamics in Endotoxemia and Polymicrobial Sepsis Scientific Reports. 05, 2021 | Pubmed ID: 34035380 Immunomagnetic Sequential Ultrafiltration (iSUF) Platform for Enrichment and Purification of Extracellular Vesicles from Biofluids Scientific Reports. 04, 2021 | Pubmed ID: 33850163 Structural Stability and Biophysical Properties of the Mega-Protein Erythrocruorin Are Regulated by Polyethylene Glycol Surface Coverage Biomacromolecules. 05, 2021 | Pubmed ID: 33821616 Purification and Analysis of a Protein Cocktail Capable of Scavenging Cell-free Hemoglobin, Heme, and Iron Transfusion. 06, 2021 | Pubmed ID: 33817808 High Fat High Sucrose Diet-induced Dyslipidemia in Guinea Pigs Journal of Applied Physiology (Bethesda, Md. : 1985). 04, 2021 | Pubmed ID: 33703947 Resuscitation from Hemorrhagic Shock After Traumatic Brain Injury with Polymerized Hemoglobin Scientific Reports. 01, 2021 | Pubmed ID: 33510204 Vessel-on-a-chip Models for Studying Microvascular Physiology, Transport, and Function in Vitro American Journal of Physiology. Cell Physiology. 01, 2021 | Pubmed ID: 33176110 Safety Profile of High Molecular Weight Polymerized Hemoglobins Transfusion. 01, 2021 | Pubmed ID: 33104250 Purification of Mega-Hemoglobin for Diverse Oxygen Therapeutic Applications ACS Biomaterials Science & Engineering. 09, 2020 | Pubmed ID: 33313397 Synthesis of Hemoglobin-Based Oxygen Carrier Nanoparticles By Desolvation Precipitation Langmuir : the ACS Journal of Surfaces and Colloids. 12, 2020 | Pubmed ID: 33205655 Early Intervention in Ischemic Tissue with Oxygen Nanocarriers Enables Successful Implementation of Restorative Cell Therapies Cellular and Molecular Bioengineering. Oct, 2020 | Pubmed ID: 33184576 Polymerized Human Hemoglobin Increases the Effectiveness of Cisplatin-based Chemotherapy in Non-small Cell Lung Cancer Oncotarget. Oct, 2020 | Pubmed ID: 33144918 Tumor Vascular Status Controls Oxygen Delivery Facilitated by Infused Polymerized Hemoglobins with Varying Oxygen Affinity PLoS Computational Biology. 08, 2020 | Pubmed ID: 32817659 Polymerized Human Hemoglobin Facilitated Modulation of Tumor Oxygenation is Dependent on Tumor Oxygenation Status and Oxygen Affinity of the Hemoglobin-based Oxygen Carrier Scientific Reports. 07, 2020 | Pubmed ID: 32647211 Hyperferritinemia in Critically Ill COVID-19 Patients - Is Ferritin the Product of Inflammation or a Pathogenic Mediator? Clinica Chimica Acta; International Journal of Clinical Chemistry. Oct, 2020 | Pubmed ID: 32579952 Apohemoglobin-haptoglobin Complexes Attenuate the Hypertensive Response to Low-molecular-weight Polymerized Hemoglobin Blood Advances. 06, 2020 | Pubmed ID: 32559292 Balance Between Oxygen Transport and Blood Rheology During Resuscitation from Hemorrhagic Shock with Polymerized Bovine Hemoglobin Journal of Applied Physiology (Bethesda, Md. : 1985). 07, 2020 | Pubmed ID: 32552431 Comprehensive Characterization of Tense and Relaxed Quaternary State Glutaraldehyde Polymerized Bovine Hemoglobin As a Function of Cross-link Density Biotechnology and Bioengineering. 08, 2020 | Pubmed ID: 32472694 Targeted Myoglobin Delivery As a Strategy for Enhancing the Sensitivity of Hypoxic Cancer Cells to Radiation IScience. Jun, 2020 | Pubmed ID: 32464594 Anti-inflammatory Effects of Haptoglobin on LPS-stimulated Macrophages: Role of HMGB1 Signaling and Implications in Chronic Wound Healing Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society. 07, 2020 | Pubmed ID: 32428978 Tangential Flow Filtration of Haptoglobin Biotechnology Progress. 09, 2020 | Pubmed ID: 32348635 Apohemoglobin-haptoglobin Complex Attenuates the Pathobiology of Circulating Acellular Hemoglobin and Heme American Journal of Physiology. Heart and Circulatory Physiology. 05, 2020 | Pubmed ID: 32302494 Poly(ethylene Glycol) Surface-Conjugated Apohemoglobin As a Synthetic Heme Scavenger Biomacromolecules. 06, 2020 | Pubmed ID: 32186855 Resuscitation From Hemorrhagic Shock With Fresh and Stored Blood and Polymerized Hemoglobin Shock (Augusta, Ga.). 10, 2020 | Pubmed ID: 32097242 Injectable Biodegradable Bi-layered Capsule for Sustained Delivery of Bevacizumab in Treating Wet Age-related Macular Degeneration Journal of Controlled Release : Official Journal of the Controlled Release Society. 04, 2020 | Pubmed ID: 31981659 Quantification of the Mean and Distribution of Hemoglobin Content in Normal Human Blood Using Cell Tracking Velocimetry Analytical Chemistry. Jan, 2020 | Pubmed ID: 31874030 Controlled Polymerization and Ultrafiltration Increase the Consistency of Polymerized Hemoglobin for Use As an Oxygen Carrier Bioconjugate Chemistry. 03, 2020 | Pubmed ID: 31868349 Novel Manufacturing Method for Producing Apohemoglobin and Its Biophysical Properties Biotechnology and Bioengineering. 01, 2020 | Pubmed ID: 31612988 Haptoglobin Administration into the Subarachnoid Space Prevents Hemoglobin-induced Cerebral Vasospasm The Journal of Clinical Investigation. 12, 2019 | Pubmed ID: 31454333 An Hb-mediated Circulating Macrophage Contributing to Pulmonary Vascular Remodeling in Sickle Cell Disease JCI Insight. 08, 2019 | Pubmed ID: 31391342 A Subpopulation of Monocytes in Normal Human Blood Has Significant Magnetic Susceptibility: Quantification and Potential Implications Cytometry. Part A : the Journal of the International Society for Analytical Cytology. May, 2019 | Pubmed ID: 30958642 Single Cell Analysis of Aged RBCs: Quantitative Analysis of the Aged Cells and Byproducts The Analyst. Jan, 2019 | Pubmed ID: 30617361 The Quaternary State of Polymerized Human Hemoglobin Regulates Oxygenation of Breast Cancer Solid Tumors: A Theoretical and Experimental Study PloS One. 2018 | Pubmed ID: 29414985 Quantification of Active Apohemoglobin Heme-Binding Sites Via Dicyanohemin Incorporation Biochemistry. 10, 2017 | Pubmed ID: 28846391 Transfusion with Packed Red Blood Cells While Awaiting Lung Transplantation is Associated with Reduced Survival After Lung Transplantation Clinical Transplantation. Dec, 2016 | Pubmed ID: 27653312 Haptoglobin Preserves Vascular Nitric Oxide Signaling During Hemolysis American Journal of Respiratory and Critical Care Medicine. 05, 2016 | Pubmed ID: 26694989 Cotransplantation of Polymerized Hemoglobin Reduces β-Cell Hypoxia and Improves β-Cell Function in Intramuscular Islet Grafts Transplantation. Oct, 2015 | Pubmed ID: 26426924 Methemoglobin is an Endogenous Toll-like Receptor 4 Ligand-relevance to Subarachnoid Hemorrhage International Journal of Molecular Sciences. Mar, 2015 | Pubmed ID: 25751721 Evaluating the Capacity to Generate and Preserve Nitric Oxide Bioactivity in Highly Purified Earthworm Erythrocruorin: a Giant Polymeric Hemoglobin with Potential Blood Substitute Properties The Journal of Biological Chemistry. Jan, 2015 | Pubmed ID: 25371199 Modeling Hemoglobin and Hemoglobin:haptoglobin Complex Clearance in a Non-rodent Species-pharmacokinetic and Therapeutic Implications Frontiers in Physiology. 2014 | Pubmed ID: 25346694 Hemoglobin Regulates the Migration of Glioma Cells Along Poly(ε-caprolactone)-aligned Nanofibers Biotechnology Progress. Sep-Oct, 2014 | Pubmed ID: 25044995 Blood Substitutes Annual Review of Biomedical Engineering. Jul, 2014 | Pubmed ID: 24819476 Scaffold Architecture Controls Insulinoma Clustering, Viability, and Insulin Production Tissue Engineering. Part A. Jul, 2014 | Pubmed ID: 24410263 Addition of Ascorbic Acid Solution to Stored Murine Red Blood Cells Increases Posttransfusion Recovery and Decreases Microparticles and Alloimmunization Transfusion. Oct, 2013 | Pubmed ID: 23384196 Biophysical Properties of Lumbricus Terrestris Erythrocruorin and Its Potential Use As a Red Blood Cell Substitute Journal of Functional Biomaterials. Jan, 2012 | Pubmed ID: 24956515 Oxygen Delivery During Extreme Anemia with Ultra-pure Earthworm Hemoglobin Life Sciences. Oct, 2012 | Pubmed ID: 22982347 The Reactivity of Polymersome Encapsulated Hemoglobin with Physiologically Important Gaseous Ligands: Oxygen, Carbon Monoxide and Nitric Oxide Macromolecules. Mar, 2012 | Pubmed ID: 22865934 High-efficiency Matrix Modulus-induced Cardiac Differentiation of Human Mesenchymal Stem Cells Inside a Thermosensitive Hydrogel Acta Biomaterialia. Oct, 2012 | Pubmed ID: 22729021 Hemoglobin Encapsulated Poly(ethylene Glycol) Surface Conjugated Vesicles Attenuate Vasoactivity of Cell-free Hemoglobin Current Drug Discovery Technologies. Sep, 2012 | Pubmed ID: 22564169 Site-selective Glycosylation of Hemoglobin with Variable Molecular Weight Oligosaccharides: Potential Alternative to PEGylation Journal of the American Chemical Society. May, 2012 | Pubmed ID: 22489605 Encapsulation of Hemoglobin Inside Liposomes Surface Conjugated with Poly(ethylene Glycol) Attenuates Their Reactions with Gaseous Ligands and Regulates Nitric Oxide Dependent Vasodilation Biotechnology Progress. May-Jun, 2012 | Pubmed ID: 22467599 Down Selection of Polymerized Bovine Hemoglobins for Use As Oxygen Releasing Therapeutics in a Guinea Pig Model Toxicological Sciences : an Official Journal of the Society of Toxicology. Jun, 2012 | Pubmed ID: 22416071 Hypervolemic Infusion of Lumbricus Terrestris Erythrocruorin Purified by Tangential-flow Filtration Transfusion. Feb, 2012 | Pubmed ID: 22304397 Simulation of NO and O(2) Transport Facilitated by Polymerized Hemoglobin Solutions in an Arteriole That Takes into Account Wall Shear Stress-induced NO Production Biophysical Chemistry. Jan, 2012 | Pubmed ID: 22285312 Liposomes Surface Conjugated with Human Hemoglobin Target Delivery to Macrophages Biotechnology and Bioengineering. Mar, 2012 | Pubmed ID: 22012493 Small-volume Resuscitation from Hemorrhagic Shock with Polymerized Human Serum Albumin The American Journal of Emergency Medicine. Nov, 2011 | Pubmed ID: 22100469 Simple Method for Preparing Poly(ethylene Glycol)-surface-conjugated Liposome-encapsulated Hemoglobins: Physicochemical Properties, Long-term Storage Stability, and Their Reactions with O2, CO, and NO Langmuir : the ACS Journal of Surfaces and Colloids. Jul, 2011 | Pubmed ID: 21678920 Synthesis, Biophysical Properties, and Oxygenation Potential of Variable Molecular Weight Glutaraldehyde-polymerized Bovine Hemoglobins with Low and High Oxygen Affinity Biotechnology Progress. Apr, 2011 | Pubmed ID: 21584950 Structure of Greyhound Hemoglobin: Origin of High Oxygen Affinity Acta Crystallographica. Section D, Biological Crystallography. May, 2011 | Pubmed ID: 21543841 Small-volume Resuscitation from Hemorrhagic Shock Using High-molecular-weight Tense-state Polymerized Hemoglobins The Journal of Trauma. Oct, 2011 | Pubmed ID: 21336190 Development of a Dichloroacetic Acid-hemoglobin Conjugate As a Potential Targeted Anti-cancer Therapeutic Biotechnology and Bioengineering. Jun, 2011 | Pubmed ID: 21328317 Synthesis and Biophysical Properties of Polymerized Human Serum Albumin Biotechnology Progress. Jan-Feb, 2011 | Pubmed ID: 21312376 Effects of T- and R-state Stabilization on Deoxyhemoglobin-nitrite Reactions and Stimulation of Nitric Oxide Signaling Nitric Oxide : Biology and Chemistry. Aug, 2011 | Pubmed ID: 21277987 Purification of Hemoglobin from Red Blood Cells Using Tangential Flow Filtration and Immobilized Metal Ion Affinity Chromatography Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. Jan, 2011 | Pubmed ID: 21195679 Biophysical Properties and Oxygenation Potential of High-molecular-weight Glutaraldehyde-polymerized Human Hemoglobins Maintained in the Tense and Relaxed Quaternary States Tissue Engineering. Part A. Apr, 2011 | Pubmed ID: 20979534 Polymerization of Human Hemoglobin Using the Crosslinker 1,11-bis(maleimido)triethylene Glycol for Use As an Oxygen Carrier Biotechnology Progress. Sep-Oct, 2010 | Pubmed ID: 20564360 Hemoglobin Regulates the Metabolic and Synthetic Function of Rat Insulinoma Cells Cultured in a Hollow Fiber Bioreactor Biotechnology and Bioengineering. Oct, 2010 | Pubmed ID: 20552668 Hemoglobin Regulates the Metabolic, Synthetic, Detoxification, and Biotransformation Functions of Hepatoma Cells Cultured in a Hollow Fiber Bioreactor Tissue Engineering. Part A. Oct, 2010 | Pubmed ID: 20528678 High Throughput Assembly of Spatially Controlled 3D Cell Clusters on a Micro/nanoplatform Lab on a Chip. Mar, 2010 | Pubmed ID: 20221567 Synthesis, Biophysical Properties and Pharmacokinetics of Ultrahigh Molecular Weight Tense and Relaxed State Polymerized Bovine Hemoglobins Biomaterials. May, 2010 | Pubmed ID: 20149433 Functional Comparison of Hemoglobin Purified by Different Methods and Their Biophysical Implications Biotechnology and Bioengineering. May, 2010 | Pubmed ID: 20073089 Tissue Oxygenation After Exchange Transfusion with Ultrahigh-molecular-weight Tense- and Relaxed-state Polymerized Bovine Hemoglobins American Journal of Physiology. Heart and Circulatory Physiology. Mar, 2010 | Pubmed ID: 20061539 Large Scale Production of Vesicles by Hollow Fiber Extrusion: a Novel Method for Generating Polymersome Encapsulated Hemoglobin Dispersions Langmuir : the ACS Journal of Surfaces and Colloids. Apr, 2010 | Pubmed ID: 20000689 Mixtures of Hemoglobin-based Oxygen Carriers and Perfluorocarbons Exhibit a Synergistic Effect in Oxygenating Hepatic Hollow Fiber Bioreactors Biotechnology and Bioengineering. Feb, 2010 | Pubmed ID: 19816963 Effects of the Molecular Mass of Tense-state Polymerized Bovine Hemoglobin on Blood Pressure and Vasoconstriction Journal of Applied Physiology (Bethesda, Md. : 1985). Nov, 2009 | Pubmed ID: 19745190 The Quaternary Structure of Tetrameric Hemoglobin Regulates the Oxygen Affinity of Polymerized Hemoglobin Biotechnology Progress. Nov-Dec, 2009 | Pubmed ID: 19725116 Purification of Hemoglobin by Tangential Flow Filtration with Diafiltration Biotechnology Progress. Sep-Oct, 2009 | Pubmed ID: 19621471 Perfluorocarbon Facilitated O(2) Transport in a Hepatic Hollow Fiber Bioreactor Biotechnology Progress. Sep-Oct, 2009 | Pubmed ID: 19565662 Tangential Flow Filtration of Hemoglobin Biotechnology Progress. Jan-Feb, 2009 | Pubmed ID: 19224583 Hemoglobin-based Oxygen Carrier and Convection Enhanced Oxygen Transport in a Hollow Fiber Bioreactor Biotechnology and Bioengineering. Apr, 2009 | Pubmed ID: 19072844 Site-selective Glycosylation of Hemoglobin on Cys Beta93 Bioconjugate Chemistry. Nov, 2008 | Pubmed ID: 18925771 Biocompatible and Biodegradable Polymersome Encapsulated Hemoglobin: a Potential Oxygen Carrier Bioconjugate Chemistry. May, 2008 | Pubmed ID: 18442283 Preparation of Ultrapure Bovine and Human Hemoglobin by Anion Exchange Chromatography Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. May, 2008 | Pubmed ID: 18359279 Purification of Bovine Hemoglobin Via Fast Performance Liquid Chromatography Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. Sep, 2007 | Pubmed ID: 17581802 Hemoglobin-based O2 Carrier O2 Affinity and Capillary Inlet PO2 Are Important Factors That Influence O2 Transport in a Capillary Biotechnology Progress. Jul-Aug, 2007 | Pubmed ID: 17555329 Self-assembled Poly(butadiene)-b-poly(ethylene Oxide) Polymersomes As Paclitaxel Carriers Biotechnology Progress. Jan-Feb, 2007 | Pubmed ID: 17269699 A Rat Lung Transplantation Model of Warm Ischemia/Reperfusion Injury: Optimizations to Improve Outcomes Yong Gyu Lee1,2, Jung-Lye Kim1,2, Andre F. Palmer3, Brenda F. Reader4, Jianjie Ma1, Sylvester M. Black2,4, Bryan A. Whitson1,2 1Department of Surgery Division of Cardiac Surgery, The Ohio State University Wexner Medical Center, 2The Collaboration for Organ Perfusion, Protection, Engineering and Regeneration (COPPER) Laboratory, The Ohio State University College of Medicine, 3William G. Lowrie Department of Chemical and Biomolecular Engineering, College of Engineering, The Ohio State University, 4Comprehensive Transplant Center, The Ohio State University Wexner Medical Center JoVE 62445 Medicine
A Rat Lung Transplantation Model of Warm Ischemia/Reperfusion Injury: Optimizations to Improve Outcomes Yong Gyu Lee1,2, Jung-Lye Kim1,2, Andre F. Palmer3, Brenda F. Reader4, Jianjie Ma1, Sylvester M. Black2,4, Bryan A. Whitson1,2 1Department of Surgery Division of Cardiac Surgery, The Ohio State University Wexner Medical Center, 2The Collaboration for Organ Perfusion, Protection, Engineering and Regeneration (COPPER) Laboratory, The Ohio State University College of Medicine, 3William G. Lowrie Department of Chemical and Biomolecular Engineering, College of Engineering, The Ohio State University, 4Comprehensive Transplant Center, The Ohio State University Wexner Medical Center JoVE 62445 Medicine
