Andrew J. H. Smith

Publications

• Identification and Single-Cell Functional Characterization of an Endodermally Biased Pluripotent Substate in Human Embryonic Stem Cells
  Stem Cell Reports. 06, 2018  |   Pubmed ID: 29779895
• A Human IPS Model Implicates Embryonic B-Myeloid Fate Restriction As Developmental Susceptibility to B Acute Lymphoblastic Leukemia-Associated ETV6-RUNX1
  Developmental Cell. 02, 2018  |   Pubmed ID: 29290585
• DNA Methylation of Intragenic CpG Islands Depends on Their Transcriptional Activity During Differentiation and Disease
  Proceedings of the National Academy of Sciences of the United States of America. 09, 2017  |   Pubmed ID: 28827334
• Intrinsic Factors and the Embryonic Environment Influence the Formation of Extragonadal Teratomas During Gestation
  BMC Developmental Biology. 2015  |   Pubmed ID: 26453549
• Hes1 Desynchronizes Differentiation of Pluripotent Cells by Modulating STAT3 Activity
  Stem Cells (Dayton, Ohio). Aug, 2013  |   Pubmed ID: 23649667
• Tcf15 Primes Pluripotent Cells for Differentiation
  Cell Reports. Feb, 2013  |   Pubmed ID: 23395635
• Transposon-mediated BAC Transgenesis in Human ES Cells
  Nucleic Acids Research. Oct, 2012  |   Pubmed ID: 22753106
• Genomically Humanized Mice: Technologies and Promises
  Nature Reviews. Genetics. Dec, 2011  |   Pubmed ID: 22179716
• Foxn1 Regulates Lineage Progression in Cortical and Medullary Thymic Epithelial Cells but is Dispensable for Medullary Sublineage Divergence
  PLoS Genetics. Nov, 2011  |   Pubmed ID: 22072979
• An Interspecies Analysis Reveals a Key Role for Unmethylated CpG Dinucleotides in Vertebrate Polycomb Complex Recruitment
  The EMBO Journal. 2011  |   Pubmed ID: 22056776
• Polycomb Eviction As a New Distant Enhancer Function
  Genes & Development. Aug, 2011  |   Pubmed ID: 21828268
• Dominant Role of the P110beta Isoform of PI3K over P110alpha in Energy Homeostasis Regulation by POMC and AgRP Neurons
  Cell Metabolism. Nov, 2009  |   Pubmed ID: 19883613
• Association Between Active Genes Occurs at Nuclear Speckles and is Modulated by Chromatin Environment
  The Journal of Cell Biology. Sep, 2008  |   Pubmed ID: 18809724
• The P110beta Isoform of Phosphoinositide 3-kinase Signals Downstream of G Protein-coupled Receptors and is Functionally Redundant with P110gamma
  Proceedings of the National Academy of Sciences of the United States of America. Jun, 2008  |   Pubmed ID: 18544649
• Control of Axonal Growth and Regeneration of Sensory Neurons by the P110delta PI 3-kinase
  PloS One. Sep, 2007  |   Pubmed ID: 17846664
• Experimental Acute Pancreatitis in PAP/HIP Knock-out Mice
  Gut. Aug, 2007  |   Pubmed ID: 17409121
• Manipulating the Mouse Genome to Engineer Precise Functional Syntenic Replacements with Human Sequence
  Cell. Jan, 2007  |   Pubmed ID: 17218265
• Loss of Atrx Affects Trophoblast Development and the Pattern of X-inactivation in Extraembryonic Tissues
  PLoS Genetics. Apr, 2006  |   Pubmed ID: 16628246
• Neurofascins Are Required to Establish Axonal Domains for Saltatory Conduction
  Neuron. Dec, 2005  |   Pubmed ID: 16337912
• Expression of Butyrophilin (Btn1a1) in Lactating Mammary Gland is Essential for the Regulated Secretion of Milk-lipid Droplets
  Proceedings of the National Academy of Sciences of the United States of America. Jul, 2004  |   Pubmed ID: 15226505
• Essential Role for Proteinase-activated Receptor-2 in Arthritis
  The Journal of Clinical Investigation. Jan, 2003  |   Pubmed ID: 12511586
• Cre-loxP Chromosome Engineering of a Targeted Deletion in the Mouse Corresponding to the 3p21.3 Region of Homozygous Loss in Human Tumours
  Oncogene. Jul, 2002  |   Pubmed ID: 12085230
• Role of Beta-dystrobrevin in Nonmuscle Dystrophin-associated Protein Complex-like Complexes in Kidney and Liver
  Molecular and Cellular Biology. Nov, 2001  |   Pubmed ID: 11585924
• Multiomics Analyses of HNF4α Protein Domain Function During Human Pluripotent Stem Cell Differentiation
  IScience.   |   Pubmed ID: 31185456