Articles by Anjaparavanda P. Naren In JoVE (1) Methods to Study Mrp4-containing Macromolecular Complexes in the Regulation of Fibroblast Migration Other Publications (0) Articles by Anjaparavanda P. Naren in JoVE Developmental Biology Methods to Study Mrp4-containing Macromolecular Complexes in the Regulation of Fibroblast Migration Chandrima Sinha*1,2, Kavisha Arora*1, Anjaparavanda P. Naren1,2 1Division of Pulmonary Medicine, Department of Pediatrics, Cincinnati Children’s Hospital Medical Center, 2Department of Physiology, University of Tennessee Health Science Center MRP4 regulates various cyclic nucleotide-dependent signaling events including a recently elucidated role in cell migration. We describe a direct, but multifaceted approach to unravel the downstream molecular targets of MRP4 resulting in identification of a unique MRP4 interactome that plays key roles in the fine-tuned regulation of fibroblast migration.
