Ann F. Chambers

Publications

• CORRIGENDUM: Stage of Breast Cancer Progression Influences Cellular Response to Activation of the WNT/Planar Cell Polarity Pathway
  Scientific Reports. 2015  |   Pubmed ID: 25613050
• Stage of Breast Cancer Progression Influences Cellular Response to Activation of the WNT/planar Cell Polarity Pathway
  Scientific Reports. 2014  |   Pubmed ID: 25204426
• Invadopodia Are Required for Cancer Cell Extravasation and Are a Therapeutic Target for Metastasis
  Cell Reports. Sep, 2014  |   Pubmed ID: 25176655
• Tumor-α9β1 Integrin-mediated Signaling Induces Breast Cancer Growth and Lymphatic Metastasis Via the Recruitment of Cancer-associated Fibroblasts
  Journal of Molecular Medicine (Berlin, Germany). Dec, 2014  |   Pubmed ID: 25099519
• BRCA2 Inhibition Enhances Cisplatin-mediated Alterations in Tumor Cell Proliferation, Metabolism, and Metastasis
  Molecular Oncology. Dec, 2014  |   Pubmed ID: 24974076
• Cyclin A2, a Novel Regulator of EMT
  Cellular and Molecular Life Sciences : CMLS. Dec, 2014  |   Pubmed ID: 24879294
• A Method to Validate Quantitative High-frequency Power Doppler Ultrasound with Fluorescence in Vivo Video Microscopy
  Ultrasound in Medicine & Biology. Aug, 2014  |   Pubmed ID: 24798391
• Radiation-induced Lung Injury After Concurrent Neoadjuvant Chemoradiotherapy for Locally Advanced Breast Cancer
  Acta Oncologica (Stockholm, Sweden). May, 2014  |   Pubmed ID: 24456500
• Assessment of Osteopontin in Early Breast Cancer: Correlative Study in a Randomised Clinical Trial
  Breast Cancer Research : BCR. 2014  |   Pubmed ID: 24451146
• Hypoxia Promotes Tumor Cell Motility Via RhoA and ROCK1 Signaling Pathways
  Proceedings of the National Academy of Sciences of the United States of America. Jan, 2014  |   Pubmed ID: 24398519
• Brain Metastases from Breast Cancer: Lessons from Experimental Magnetic Resonance Imaging Studies and Clinical Implications
  Journal of Molecular Medicine (Berlin, Germany). Jan, 2014  |   Pubmed ID: 24306136
• In Vivo Magnetic Resonance Imaging for Investigating the Development and Distribution of Experimental Brain Metastases Due to Breast Cancer
  Translational Oncology. Jun, 2012  |   Pubmed ID: 22741041
• Assessing Cancer Cell Migration and Metastatic Growth in Vivo in the Chick Embryo Using Fluorescence Intravital Imaging
  Methods in Molecular Biology (Clifton, N.J.). 2012  |   Pubmed ID: 22700400
• Co-expression of α9β1 Integrin and VEGF-D Confers Lymphatic Metastatic Ability to a Human Breast Cancer Cell Line MDA-MB-468LN
  PloS One. 2012  |   Pubmed ID: 22545097
• Imaging the Impact of Chemically Inducible Proteins on Cellular Dynamics in Vivo
  PloS One. 2012  |   Pubmed ID: 22276156
• Neuropeptide Y Stimulates Proliferation and Migration in the 4T1 Breast Cancer Cell Line
  International Journal of Cancer. Journal International Du Cancer. Jul, 2012  |   Pubmed ID: 21823118
• An Emerging Role for the Nuclear Localization of Maspin in the Suppression of Tumor Progression and Metastasis (1) (1) This Article is Part of Special Issue Entitled Asilomar Chromatin and Has Undergone the Journal's Usual Peer Review Process
  Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. Nov, 2011  |   Pubmed ID: 22047058
• β1-integrin: a Potential Therapeutic Target in the Battle Against Cancer Recurrence
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Dec, 2011  |   Pubmed ID: 21900388
• Osteopontin Increases Breast Cancer Cell Sensitivity to Specific Signaling Pathway Inhibitors in Preclinical Models
  Cancer Biology & Therapy. Oct, 2011  |   Pubmed ID: 21795853
• In Vivo Characterization of Changing Blood-tumor Barrier Permeability in a Mouse Model of Breast Cancer Metastasis: a Complementary Magnetic Resonance Imaging Approach
  Investigative Radiology. Nov, 2011  |   Pubmed ID: 21788908
• In Vivo Single Scan Detection of Both Iron-labeled Cells and Breast Cancer Metastases in the Mouse Brain Using Balanced Steady-state Free Precession Imaging at 1.5 T
  Journal of Magnetic Resonance Imaging : JMRI. Jul, 2011  |   Pubmed ID: 21698713
• Notch1 Inhibition Alters the CD44hi/CD24lo Population and Reduces the Formation of Brain Metastases from Breast Cancer
  Molecular Cancer Research : MCR. Jul, 2011  |   Pubmed ID: 21665937
• Pre- and Post-translational Regulation of Osteopontin in Cancer
  Journal of Cell Communication and Signaling. Jun, 2011  |   Pubmed ID: 21516514
• Nuclear Localization of Maspin is Essential for Its Inhibition of Tumor Growth and Metastasis
  Laboratory Investigation; a Journal of Technical Methods and Pathology. Aug, 2011  |   Pubmed ID: 21502940
• Gene Signatures of Breast Cancer Progression and Metastasis
  Breast Cancer Research : BCR. 2011  |   Pubmed ID: 21345283
• The Synthetic Triterpenoid CDDO-Imidazolide Suppresses Experimental Liver Metastasis
  Clinical & Experimental Metastasis. Mar, 2011  |   Pubmed ID: 21234655
• Does Tumour Dormancy Offer a Therapeutic Target?
  Nature Reviews. Cancer. Dec, 2010  |   Pubmed ID: 21048784
• Role of the Metastasis-promoting Protein Osteopontin in the Tumour Microenvironment
  Journal of Cellular and Molecular Medicine. Aug, 2010  |   Pubmed ID: 20597997
• Human 21T Breast Epithelial Cell Lines Mimic Breast Cancer Progression in Vivo and in Vitro and Show Stage-specific Gene Expression Patterns
  Laboratory Investigation; a Journal of Technical Methods and Pathology. Aug, 2010  |   Pubmed ID: 20458274
• Extracellular Matrix: a Gatekeeper in the Transition from Dormancy to Metastatic Growth
  European Journal of Cancer (Oxford, England : 1990). May, 2010  |   Pubmed ID: 20304630
• Multi-platform Whole-genome Microarray Analyses Refine the Epigenetic Signature of Breast Cancer Metastasis with Gene Expression and Copy Number
  PloS One. 2010  |   Pubmed ID: 20084286
• An Open Letter to the FDA and Other Regulatory Agencies: Preclinical Drug Development Must Consider the Impact on Metastasis
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jul, 2009  |   Pubmed ID: 25278743
• Three-dimensional Imaging and Quantification of Both Solitary Cells and Metastases in Whole Mouse Liver by Magnetic Resonance Imaging
  Cancer Research. Nov, 2009  |   Pubmed ID: 19843857
• Micrometastatic Disease and Metastatic Outgrowth: Clinical Issues and Experimental Approaches
  Future Oncology (London, England). Sep, 2009  |   Pubmed ID: 19792975
• Tumor Dormancy and Metastasis
  Advances in Cancer Research. 2009  |   Pubmed ID: 19595307
• Lymphatic Metastasis of Breast Cancer Cells is Associated with Differential Gene Expression Profiles That Predict Cancer Stem Cell-like Properties and the Ability to Survive, Establish and Grow in a Foreign Environment
  International Journal of Oncology. Aug, 2009  |   Pubmed ID: 19578743
• MDA-MB-435 and M14 Cell Lines: Identical but Not M14 Melanoma?
  Cancer Research. Jul, 2009  |   Pubmed ID: 19549886
• New Dual Monoclonal ELISA for Measuring Plasma Osteopontin As a Biomarker Associated with Survival in Prostate Cancer: Clinical Validation and Comparison of Multiple ELISAs
  Clinical Chemistry. May, 2009  |   Pubmed ID: 19325010
• Effect of Anti-fibrinolytic Therapy on Experimental Melanoma Metastasis
  Clinical & Experimental Metastasis. 2009  |   Pubmed ID: 19082867
• Introduction to Special Issue on 'epigenetic and Physiological Regulation of Metastasis'
  Clinical & Experimental Metastasis. 2009  |   Pubmed ID: 18925360
• Changes over Time of Extracellular Domain of HER2 (ECD/HER2) Serum Levels Have Prognostic Value in Metastatic Breast Cancer
  Breast Cancer Research and Treatment. Apr, 2009  |   Pubmed ID: 18437556
• Influence of Diet on Metastasis and Tumor Dormancy
  Clinical & Experimental Metastasis. 2009  |   Pubmed ID: 18386136
• Putative Growth Characteristics of Micrometastatic Breast Cancer
  Breast Cancer Research : BCR. 2008  |   Pubmed ID: 19090969
• Chapter 9. Intravital Videomicroscopy in Angiogenesis Research
  Methods in Enzymology. 2008  |   Pubmed ID: 19007666
• New Clinical and Experimental Approaches for Studying Tumor Dormancy: Does Tumor Dormancy Offer a Therapeutic Target?
  APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica. Jul-Aug, 2008  |   Pubmed ID: 18834402
• Distinct Karyotypes in Three Breast Cancer Cell Lines --21PTCi, 21NTCi, and 21MT-1 --derived from the Same Patient and Representing Different Stages of Tumor Progression
  Cancer Genetics and Cytogenetics. Oct, 2008  |   Pubmed ID: 18786440
• Inhibition of Metastatic Outgrowth from Single Dormant Tumor Cells by Targeting the Cytoskeleton
  Cancer Research. Aug, 2008  |   Pubmed ID: 18676848
• Epigenetic Mapping and Functional Analysis in a Breast Cancer Metastasis Model Using Whole-genome Promoter Tiling Microarrays
  Breast Cancer Research : BCR. 2008  |   Pubmed ID: 18638373
• Ex-vivo Cellular MRI with B-SSFP: Quantitative Benefits of 3T over 1.5 T
  Magma (New York, N.Y.). Jul, 2008  |   Pubmed ID: 18581153
• Contrast-enhanced Microcomputed Tomography Using Intraperitoneal Contrast Injection for the Assessment of Tumor-burden in Liver Metastasis Models
  Investigative Radiology. Jul, 2008  |   Pubmed ID: 18580331
• BRMS1 Suppresses Breast Cancer Metastasis in Multiple Experimental Models of Metastasis by Reducing Solitary Cell Survival and Inhibiting Growth Initiation
  Clinical & Experimental Metastasis. 2008  |   Pubmed ID: 18543067
• Downregulation of Osteopontin Contributes to Metastasis Suppression by Breast Cancer Metastasis Suppressor 1
  International Journal of Cancer. Journal International Du Cancer. Aug, 2008  |   Pubmed ID: 18470911
• Molecular Cytogenetic Characterization of Human Breast Cancer Cell Line MDA-MB-468 and Its Variant 468LN, Which Displays Aggressive Lymphatic Metastasis
  Cancer Genetics and Cytogenetics. Feb, 2008  |   Pubmed ID: 18262045
• Noninvasive Quantification of Tumor Volume in Preclinical Liver Metastasis Models Using Contrast-enhanced X-ray Computed Tomography
  Investigative Radiology. Feb, 2008  |   Pubmed ID: 18197061
• The Thrombin Inhibitor Argatroban Reduces Breast Cancer Malignancy and Metastasis Via Osteopontin-dependent and Osteopontin-independent Mechanisms
  Breast Cancer Research and Treatment. Nov, 2008  |   Pubmed ID: 18097747
• Myxoma Virus Oncolysis of Primary and Metastatic B16F10 Mouse Tumors in Vivo
  Molecular Therapy : the Journal of the American Society of Gene Therapy. Jan, 2008  |   Pubmed ID: 17998900
• Osteopontin Expression in Normal Skin and Non-melanoma Skin Tumors
  The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. Jan, 2008  |   Pubmed ID: 17938278
• A New Breast Cancer Model for Lymphatic Metastasis
  Cancer Treatment and Research. 2007  |   Pubmed ID: 17953414
• Osteopontin Overexpression in Breast Cancer: Knowledge Gained and Possible Implications for Clinical Management
  Journal of Cellular Biochemistry. Nov, 2007  |   Pubmed ID: 17721886
• Tumour Dormancy in Breast Cancer: an Update
  Breast Cancer Research : BCR. 2007  |   Pubmed ID: 17561992
• The Biology of Metastasis to a Sanctuary Site
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Mar, 2007  |   Pubmed ID: 17363518
• Breast Cancer Metastasis Suppressor 1 (BRMS1) Inhibits Osteopontin Transcription by Abrogating NF-kappaB Activation
  Molecular Cancer. 2007  |   Pubmed ID: 17227585
• Brain Metastases of Breast Cancer
  Breast Disease. 2006-2007  |   Pubmed ID: 17473372
• Tumor Dormancy and Cancer Stem Cells: Implications for the Biology and Treatment of Breast Cancer Metastasis
  Breast Disease. 2006-2007  |   Pubmed ID: 17473368
• In Vivo Inhibition of Growth of Human Tumor Lines by Flavonoid Fractions from Cranberry Extract
  Nutrition and Cancer. 2006  |   Pubmed ID: 17176222
• In Vivo MRI of Cancer Cell Fate at the Single-cell Level in a Mouse Model of Breast Cancer Metastasis to the Brain
  Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. Nov, 2006  |   Pubmed ID: 17029229
• Tumor Dormancy and the Role of Metastasis Suppressor Genes in Regulating Ectopic Growth
  Future Oncology (London, England). Oct, 2006  |   Pubmed ID: 17026454
• Breast Cancer Metastasis Progression As Revealed by Intravital Videomicroscopy
  Expert Review of Anticancer Therapy. Sep, 2006  |   Pubmed ID: 17020460
• Dormancy of Solitary Metastatic Cells
  Cell Cycle (Georgetown, Tex.). Aug, 2006  |   Pubmed ID: 16861927
• Osteopontin Knockdown Suppresses Tumorigenicity of Human Metastatic Breast Carcinoma, MDA-MB-435
  Clinical & Experimental Metastasis. 2006  |   Pubmed ID: 16830223
• Role of the Integrin-binding Protein Osteopontin in Lymphatic Metastasis of Breast Cancer
  The American Journal of Pathology. Jul, 2006  |   Pubmed ID: 16816376
• Osteopontin Induction of Hyaluronan Synthase 2 Expression Promotes Breast Cancer Malignancy
  The Journal of Biological Chemistry. Aug, 2006  |   Pubmed ID: 16807238
• Molecular Mechanisms of Metastasis
  Cancer Metastasis Reviews. Jun, 2006  |   Pubmed ID: 16770533
• Serial Plasma Osteopontin Levels Have Prognostic Value in Metastatic Breast Cancer
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jun, 2006  |   Pubmed ID: 16740755
• Time-course Characterization of the Computed Tomography Contrast Enhancement of an Iodinated Blood-pool Contrast Agent in Mice Using a Volumetric Flat-panel Equipped Computed Tomography Scanner
  Investigative Radiology. Apr, 2006  |   Pubmed ID: 16523021
• Ovarian Cancer Biomarkers in Urine
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jan, 2006  |   Pubmed ID: 16428467
• In Vivo Magnetic Resonance Imaging of Single Cells in Mouse Brain with Optical Validation
  Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. Jan, 2006  |   Pubmed ID: 16342157
• Enhanced Cell Surface CD44 Variant (v6, V9) Expression by Osteopontin in Breast Cancer Epithelial Cells Facilitates Tumor Cell Migration: Novel Post-transcriptional, Post-translational Regulation
  Clinical & Experimental Metastasis. 2005  |   Pubmed ID: 16691370
• Expression of Osteopontin and HGF/met in Adult Soft Tissue Tumors
  Cancer Biology & Therapy. Dec, 2005  |   Pubmed ID: 16258259
• A New Model for Lymphatic Metastasis: Development of a Variant of the MDA-MB-468 Human Breast Cancer Cell Line That Aggressively Metastasizes to Lymph Nodes
  Clinical & Experimental Metastasis. 2005  |   Pubmed ID: 16170671
• Plasma Osteopontin Levels Are Predictive of Disease Stage in Patients with Transitional Cell Carcinoma of the Bladder
  BJU International. Oct, 2005  |   Pubmed ID: 16153205
• Re: Medroxyprogesterone Acetate and Metastases: of Mice and (wo)men
  Journal of the National Cancer Institute. Aug, 2005  |   Pubmed ID: 16106028
• Three-dimensional High-frequency Ultrasound Imaging for Longitudinal Evaluation of Liver Metastases in Preclinical Models
  Cancer Research. Jun, 2005  |   Pubmed ID: 15958568
• Osteopontin Induces Multiple Changes in Gene Expression That Reflect the Six "hallmarks of Cancer" in a Model of Breast Cancer Progression
  Molecular Carcinogenesis. Aug, 2005  |   Pubmed ID: 15864800
• Dietary Genistein Reduces Metastasis in a Postsurgical Orthotopic Breast Cancer Model
  Cancer Research. Apr, 2005  |   Pubmed ID: 15833874
• Detection and Quantification of Circulating Tumor Cells in Mouse Models of Human Breast Cancer Using Immunomagnetic Enrichment and Multiparameter Flow Cytometry
  Cytometry. Part A : the Journal of the International Society for Analytical Cytology. May, 2005  |   Pubmed ID: 15810015
• Mapping of the Functional Microcirculation in Vital Organs Using Contrast-enhanced in Vivo Video Microscopy
  American Journal of Physiology. Heart and Circulatory Physiology. Jan, 2005  |   Pubmed ID: 15388500
• Experimental Metastasis Assays in the Chick Embryo
  Current Protocols in Cell Biology / Editorial Board, Juan S. Bonifacino ... [et Al.]. Feb, 2004  |   Pubmed ID: 18228449
• Therapeutic Targets for Antimetastatic Therapy
  Expert Opinion on Therapeutic Targets. Dec, 2004  |   Pubmed ID: 15584860
• In Vivo Videomicroscopy Reveals Differential Effects of the Vascular-targeting Agent ZD6126 and the Anti-angiogenic Agent ZD6474 on Vascular Function in a Liver Metastasis Model
  Angiogenesis. 2004  |   Pubmed ID: 15516836
• A Flavonoid Fraction from Cranberry Extract Inhibits Proliferation of Human Tumor Cell Lines
  The Journal of Nutrition. Jun, 2004  |   Pubmed ID: 15173424
• Surface-enhanced Laser Desorption/ionization-time of Flight-mass Spectrometry (SELDI-TOF-MS): a New Proteomic Urinary Test for Patients with Urolithiasis
  Journal of Clinical Laboratory Analysis. 2004  |   Pubmed ID: 15103681
• Correlation of Osteopontin Protein Expression and Pathological Stage Across a Wide Variety of Tumor Histologies
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jan, 2004  |   Pubmed ID: 14734468
• Osteopontin Identified As Colon Cancer Tumor Progression Marker
  Comptes Rendus Biologies. Oct-Nov, 2003  |   Pubmed ID: 14744111
• Ineffectiveness of Doxorubicin Treatment on Solitary Dormant Mammary Carcinoma Cells or Late-developing Metastases
  Breast Cancer Research and Treatment. Dec, 2003  |   Pubmed ID: 14703067
• Evaluating the Role of Serine Protease Inhibition in the Management of Tumor Micrometastases
  Oncology (Williston Park, N.Y.). Oct, 2003  |   Pubmed ID: 14606367
• The Role of Apoptosis in Tumor Progression and Metastasis
  Current Molecular Medicine. Nov, 2003  |   Pubmed ID: 14601637
• Beta(3) Integrin Expression Increases Breast Carcinoma Cell Responsiveness to the Malignancy-enhancing Effects of Osteopontin
  Molecular Cancer Research : MCR. Sep, 2003  |   Pubmed ID: 14517343
• Estrous Cycle Influences Organ-specific Metastasis of B16F10 Melanoma Cells
  Cancer Research. Aug, 2003  |   Pubmed ID: 12941790
• Osteopontin (Eta-1) and Fibroblast Growth Factor-2 Cross-talk in Angiogenesis
  Journal of Immunology (Baltimore, Md. : 1950). Jul, 2003  |   Pubmed ID: 12847283
• Osteopontin and Colon Cancer Progression
  Clinical & Experimental Metastasis. 2003  |   Pubmed ID: 12650611
• Transcriptional Regulation of Osteopontin and the Metastatic Phenotype: Evidence for a Ras-activated Enhancer in the Human OPN Promoter
  Clinical & Experimental Metastasis. 2003  |   Pubmed ID: 12650610
• Osteopontin-induced Migration of Human Mammary Epithelial Cells Involves Activation of EGF Receptor and Multiple Signal Transduction Pathways
  Oncogene. Feb, 2003  |   Pubmed ID: 12606946
• Cancer Spread and Micrometastasis Development: Quantitative Approaches for in Vivo Models
  BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology. Oct, 2002  |   Pubmed ID: 12325121
• Plasma Osteopontin: Associations with Survival and Metastasis to Bone in Men with Hormone-refractory Prostate Carcinoma
  Cancer. Aug, 2002  |   Pubmed ID: 12209742
• Dissemination and Growth of Cancer Cells in Metastatic Sites
  Nature Reviews. Cancer. Aug, 2002  |   Pubmed ID: 12154349
• Osteopontin Identified As Lead Marker of Colon Cancer Progression, Using Pooled Sample Expression Profiling
  Journal of the National Cancer Institute. Apr, 2002  |   Pubmed ID: 11929952
• Persistence of Solitary Mammary Carcinoma Cells in a Secondary Site: a Possible Contributor to Dormancy
  Cancer Research. Apr, 2002  |   Pubmed ID: 11929839
• Activated Ras Regulates the Proliferation/apoptosis Balance and Early Survival of Developing Micrometastases
  Cancer Research. Feb, 2002  |   Pubmed ID: 11830548
• Mapping of Functional Epitopes of Osteopontin by Monoclonal Antibodies Raised Against Defined Internal Sequences
  Journal of Cellular Biochemistry. 2002  |   Pubmed ID: 11787071