Anna Genescà Department of Cell Biology, Physiology and Immunology Universitat Autònoma de Barcelona Biography Publications Institution JoVE Articles Anna Genescà has not added a biography. If you are Anna Genescà and would like to personalize this page please email our Author Liaison for assistance. Publications Identification of Reference Genes for RT-qPCR Data Normalisation in Aging Studies Scientific Reports. Sep, 2019 | Pubmed ID: 31562345 Delayed γH2AX Foci Disappearance in Mammary Epithelial Cells from Aged Women Reveals an Age-associated DNA Repair Defect Aging. 03, 2019 | Pubmed ID: 30875333 Radiation-Induced Malignant Transformation of Preneoplastic and Normal Breast Primary Epithelial Cells Molecular Cancer Research : MCR. 04, 2019 | Pubmed ID: 30651374 Detection of Impaired DNA Replication and Repair in Micronuclei As Indicators of Genomic Instability and Chromothripsis Methods in Molecular Biology (Clifton, N.J.). 2018 | Pubmed ID: 29564826 Distinct Sets of LncRNAs Are Differentially Modulated After Exposure to High and Low Doses of X Rays Radiation Research. Dec, 2016 | Pubmed ID: 27841703 Impaired Nuclear Functions in Micronuclei Results in Genome Instability and Chromothripsis Archives of Toxicology. Nov, 2016 | Pubmed ID: 27542123 Analysis of Residual DSBs in Ataxia-Telangiectasia Lymphoblast Cells Initiating Apoptosis BioMed Research International. 2016 | Pubmed ID: 27057549 Chromosome Bridges Maintain Kinetochore-Microtubule Attachment Throughout Mitosis and Rarely Break During Anaphase PloS One. 2016 | Pubmed ID: 26784746 Breast Primary Epithelial Cells That Escape P16-dependent Stasis Enter a Telomere-driven Crisis State Breast Cancer Research : BCR. Jan, 2016 | Pubmed ID: 26758019 Centrosome Aberrations in Human Mammary Epithelial Cells Driven by Cooperative Interactions Between P16INK4a Deficiency and Telomere-dependent Genotoxic Stress Oncotarget. Sep, 2015 | Pubmed ID: 26318587 Genomic Instability: Crossing Pathways at the Origin of Structural and Numerical Chromosome Changes Environmental and Molecular Mutagenesis. Aug, 2015 | Pubmed ID: 25784636 Aging and Radiation: Bad Companions Aging Cell. Apr, 2015 | Pubmed ID: 25645467 Telomere-dependent Genomic Integrity: Evolution of the Fusion-bridge-breakage Cycle Concept Current Pharmaceutical Design. 2014 | Pubmed ID: 24975612 Highly Sensitive Automated Method for DNA Damage Assessment: Gamma-H2AX Foci Counting and Cell Cycle Sorting International Journal of Molecular Sciences. Jul, 2013 | Pubmed ID: 23903043 Increased Mammogram-induced DNA Damage in Mammary Epithelial Cells Aged in Vitro PloS One. 2013 | Pubmed ID: 23667571 Is DNA Damage Response Ready for Action Anywhere? International Journal of Molecular Sciences. 2012 | Pubmed ID: 23109871 Telomere Dysfunction and Genome Instability Frontiers in Bioscience (Landmark Edition). Jun, 2012 | Pubmed ID: 22652771 Progressive Telomere Dysfunction Causes Cytokinesis Failure and Leads to the Accumulation of Polyploid Cells PLoS Genetics. 2012 | Pubmed ID: 22570622 Nuclear Envelope Defects Impede a Proper Response to Micronuclear DNA Lesions Mutation Research. Jan, 2012 | Pubmed ID: 21945242 Role of Telomere Dysfunction in Genetic Intratumor Diversity Advances in Cancer Research. 2011 | Pubmed ID: 21925300 Different Outcomes of Telomere-dependent Anaphase Bridges Biochemical Society Transactions. Dec, 2010 | Pubmed ID: 21118150 Genetic Activities in Micronuclei: is the DNA Entrapped in Micronuclei Lost for the Cell? Mutation Research. Jul-Sep, 2010 | Pubmed ID: 20307686 Whole Chromosome Loss is Promoted by Telomere Dysfunction in Primary Cells Genes, Chromosomes & Cancer. Apr, 2010 | Pubmed ID: 20088004 DNA Lesions Sequestered in Micronuclei Induce a Local Defective-damage Response DNA Repair. Oct, 2009 | Pubmed ID: 19683478 Radiation Sensitivity Increases with Proliferation-associated Telomere Dysfunction in Nontransformed Human Epithelial Cells Aging Cell. Aug, 2009 | Pubmed ID: 19473118 Breaks Invisible to the DNA Damage Response Machinery Accumulate in ATM-deficient Cells Genes, Chromosomes & Cancer. Sep, 2009 | Pubmed ID: 19455703 Telomere Dysfunction: a New Player in Radiation Sensitivity BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology. Dec, 2006 | Pubmed ID: 17120191 Postreplicative Joining of DNA Double-strand Breaks Causes Genomic Instability in DNA-PKcs-deficient Mouse Embryonic Fibroblasts Cancer Research. Nov, 2005 | Pubmed ID: 16288010 Telomere Dysfunction Drives Chromosomal Instability in Human Mammary Epithelial Cells Genes, Chromosomes & Cancer. Dec, 2005 | Pubmed ID: 16052508 Capping of Radiation-induced DNA Breaks in Mouse Early Embryos Journal of Radiation Research. Sep, 2004 | Pubmed ID: 15613787 Repair of DNA Broken Ends is Similar in Embryonic Fibroblasts with and Without Telomerase Radiation Research. Aug, 2004 | Pubmed ID: 15387140 Shortened Telomeres Join to DNA Breaks Interfering with Their Correct Repair Experimental Cell Research. Jul, 2003 | Pubmed ID: 12837284 In Vitro Evaluation of Oncogenic Transformation in Human Mammary Epithelial Cells Joan Repullés1,2, Mariona Terradas1,3,4, Gemma Fuster5,6,7, Anna Genescà1, Teresa Anglada1 1Department of Cell Biology, Physiology and Immunology, Universitat Autònoma de Barcelona, 2Optical Microscopy Core Facilities, IDIBELL, 3Hereditary Cancer Program, Catalan Institute of Oncology, IDIBELL, 4Program in Molecular Mechanisms and Experimental Therapy in Oncology (Oncobell), IDIBELL, 5New Therapeutic Strategies in Cancer Group. Department of Biochemistry and Molecular Biomedicine, School of Biology, Institute of Biomedicine, University of Barcelona (IBUB), 6Department of Biochemistry & Physiology, School of Pharmacy and Food Sciences, University of Barcelona, 7Department of Biosciences, Faculty of Sciences and Technology, University of Vic JoVE 61716 Cancer Research
In Vitro Evaluation of Oncogenic Transformation in Human Mammary Epithelial Cells Joan Repullés1,2, Mariona Terradas1,3,4, Gemma Fuster5,6,7, Anna Genescà1, Teresa Anglada1 1Department of Cell Biology, Physiology and Immunology, Universitat Autònoma de Barcelona, 2Optical Microscopy Core Facilities, IDIBELL, 3Hereditary Cancer Program, Catalan Institute of Oncology, IDIBELL, 4Program in Molecular Mechanisms and Experimental Therapy in Oncology (Oncobell), IDIBELL, 5New Therapeutic Strategies in Cancer Group. Department of Biochemistry and Molecular Biomedicine, School of Biology, Institute of Biomedicine, University of Barcelona (IBUB), 6Department of Biochemistry & Physiology, School of Pharmacy and Food Sciences, University of Barcelona, 7Department of Biosciences, Faculty of Sciences and Technology, University of Vic JoVE 61716 Cancer Research
