Anne Gatignol Virus-Cell Interactions Laboratory Lady Davis Institute for Medical Research Biography Publications Institution JoVE Articles Anne Gatignol has not added a biography. If you are Anne Gatignol and would like to personalize this page please email our Author Liaison for assistance. Publications Effective Inhibition of HIV-1 Production by Short Hairpin RNAs and Small Interfering RNAs Targeting a Highly Conserved Site in HIV-1 Gag RNA is Optimized by Evaluating Alternative Length Formats Antimicrobial Agents and Chemotherapy. Sep, 2015 | Pubmed ID: 26077260 HIV and Ribozymes Advances in Experimental Medicine and Biology. 2015 | Pubmed ID: 25757617 HIV-1 RRE RNA Acts As an RNA Silencing Suppressor by Competing with TRBP-bound SiRNAs RNA Biology. 2015 | Pubmed ID: 25668122 A Conserved Target Site in HIV-1 Gag RNA is Accessible to Inhibition by Both an HDV Ribozyme and a Short Hairpin RNA Molecular Therapy. Nucleic Acids. 2014 | Pubmed ID: 25072692 HIV-1 Translation and Its Regulation by Cellular Factors PKR and PACT Virus Research. Nov, 2014 | Pubmed ID: 25064266 Design and Evaluation of Clinically Relevant SOFA-HDV Ribozymes Targeting HIV RNA Methods in Molecular Biology (Clifton, N.J.). 2014 | Pubmed ID: 24318884 The PKR Activator, PACT, Becomes a PKR Inhibitor During HIV-1 Replication Retrovirology. 2013 | Pubmed ID: 24020926 RNA-induced Silencing Complex (RISC) Proteins PACT, TRBP, and Dicer Are SRA Binding Nuclear Receptor Coregulators Proceedings of the National Academy of Sciences of the United States of America. Apr, 2013 | Pubmed ID: 23550157 The Multiple Functions of TRBP, at the Hub of Cell Responses to Viruses, Stress, and Cancer Microbiology and Molecular Biology Reviews : MMBR. Sep, 2012 | Pubmed ID: 22933564 Enhancement of Replication of RNA Viruses by ADAR1 Via RNA Editing and Inhibition of RNA-activated Protein Kinase Journal of Virology. Sep, 2011 | Pubmed ID: 21490091 In Vitro and in Vivo Cleavage of HIV-1 RNA by New SOFA-HDV Ribozymes and Their Potential to Inhibit Viral Replication RNA Biology. Mar-Apr, 2011 | Pubmed ID: 21422817 Multiple Levels of PKR Inhibition During HIV-1 Replication Reviews in Medical Virology. Jan, 2011 | Pubmed ID: 21294215 A Role for Human Dicer in Pre-RISC Loading of SiRNAs Nucleic Acids Research. Mar, 2011 | Pubmed ID: 20972213 Hepatitis C Virus Controls Interferon Production Through PKR Activation PloS One. 2010 | Pubmed ID: 20485506 ADAR1 Interacts with PKR During Human Immunodeficiency Virus Infection of Lymphocytes and Contributes to Viral Replication Journal of Virology. Oct, 2009 | Pubmed ID: 19605474 Characterization of the TRBP Domain Required for Dicer Interaction and Function in RNA Interference BMC Molecular Biology. 2009 | Pubmed ID: 19422693 TRBP Control of PACT-induced Phosphorylation of Protein Kinase R is Reversed by Stress Molecular and Cellular Biology. Jan, 2009 | Pubmed ID: 18936160 Interactions Between the Double-stranded RNA-binding Proteins TRBP and PACT Define the Medipal Domain That Mediates Protein-protein Interactions RNA Biology. Apr-Jun, 2008 | Pubmed ID: 18421256 Combinatorial Delivery of Small Interfering RNAs Reduces RNAi Efficacy by Selective Incorporation into RISC Nucleic Acids Research. 2007 | Pubmed ID: 17660190 Transcription of HIV: Tat and Cellular Chromatin Advances in Pharmacology (San Diego, Calif.). 2007 | Pubmed ID: 17586314 Small Interfering RNAs Against the TAR RNA Binding Protein, TRBP, a Dicer Cofactor, Inhibit Human Immunodeficiency Virus Type 1 Long Terminal Repeat Expression and Viral Production Journal of Virology. May, 2007 | Pubmed ID: 17360756 New Pandemics: HIV and AIDS, HCV and Chronic Hepatitis, Influenza Virus and Flu Retrovirology. 2007 | Pubmed ID: 17270043 Trafficking of HIV-1 RNA is Mediated by Heterogeneous Nuclear Ribonucleoprotein A2 Expression and Impacts on Viral Assembly Traffic (Copenhagen, Denmark). Sep, 2006 | Pubmed ID: 17004321 Cell-specific Regulation of TRBP1 Promoter by NF-Y Transcription Factor in Lymphocytes and Astrocytes Journal of Molecular Biology. Feb, 2006 | Pubmed ID: 16343534 Dual Role of TRBP in HIV Replication and RNA Interference: Viral Diversion of a Cellular Pathway or Evasion from Antiviral Immunity? Retrovirology. 2005 | Pubmed ID: 16253139 Low TRBP Levels Support an Innate Human Immunodeficiency Virus Type 1 Resistance in Astrocytes by Enhancing the PKR Antiviral Response Journal of Virology. Oct, 2005 | Pubmed ID: 16188979 TRBP, a Regulator of Cellular PKR and HIV-1 Virus Expression, Interacts with Dicer and Functions in RNA Silencing EMBO Reports. Oct, 2005 | Pubmed ID: 16142218 Regulation of Human Immunodeficiency Virus Type 1 Gene Expression by Clade-specific Tat Proteins Journal of Virology. Jul, 2005 | Pubmed ID: 15994812 HIV-1 TAR RNA: the Target of Molecular Interactions Between the Virus and Its Host Current HIV Research. Jan, 2005 | Pubmed ID: 15638724 Identification of Staufen in the Human Immunodeficiency Virus Type 1 Gag Ribonucleoprotein Complex and a Role in Generating Infectious Viral Particles Molecular and Cellular Biology. Apr, 2004 | Pubmed ID: 15024055 Astrocyte Infection by HIV-1: Mechanisms of Restricted Virus Replication, and Role in the Pathogenesis of HIV-1-associated Dementia Current HIV Research. Oct, 2003 | Pubmed ID: 15049431 Additive Activity Between the Trans-activation Response RNA-binding Protein, TRBP2, and Cyclin T1 on HIV Type 1 Expression and Viral Production in Murine Cells AIDS Research and Human Retroviruses. Sep, 2003 | Pubmed ID: 14585207 The TAR RNA-binding Protein, TRBP, Stimulates the Expression of TAR-containing RNAs in Vitro and in Vivo Independently of Its Ability to Inhibit the DsRNA-dependent Kinase PKR The Journal of Biological Chemistry. Feb, 2003 | Pubmed ID: 12475984 Differential Regulation of HIV-1 Clade-specific B, C, and E Long Terminal Repeats by NF-kappaB and the Tat Transactivator Virology. Apr, 2002 | Pubmed ID: 12036319 Evaluering af effekt og toksicitet af RNA Målretning HIV-1 Produktion til brug i Gene eller Drug Therapy Robert J. Scarborough1,2, Kelsey L. Adams1,2, Olivier Del Corpo1,2, Aïcha Daher1, Anne Gatignol1,2,3 1Virus-Cell Interactions Laboratory, Lady Davis Institute for Medical Research, 2Department of Microbiology & Immunology, McGill University, 3Department of Medicine, McGill University Immunology and Infection
Evaluering af effekt og toksicitet af RNA Målretning HIV-1 Produktion til brug i Gene eller Drug Therapy Robert J. Scarborough1,2, Kelsey L. Adams1,2, Olivier Del Corpo1,2, Aïcha Daher1, Anne Gatignol1,2,3 1Virus-Cell Interactions Laboratory, Lady Davis Institute for Medical Research, 2Department of Microbiology & Immunology, McGill University, 3Department of Medicine, McGill University Immunology and Infection