Antje Heit Vaccine and Infectious Disease Division Fred Hutchinson Cancer Research Center Biography Publications Institution JoVE Articles Antje Heit has not added a biography. If you are Antje Heit and would like to personalize this page please email our Author Liaison for assistance. Publications Profiling Immunity to HIV Vaccines with Systems Biology Current Opinion in HIV and AIDS. Jan, 2012 | Pubmed ID: 22134340 Immunostimulatory CpG-DNA and PSA-peptide Vaccination Elicits Profound Cytotoxic T Cell Responses Urologic Oncology. Oct, 2011 | Pubmed ID: 21982682 Adjuvanticity of a Synthetic Cord Factor Analogue for Subunit Mycobacterium Tuberculosis Vaccination Requires FcRgamma-Syk-Card9-dependent Innate Immune Activation The Journal of Experimental Medicine. Jan, 2009 | Pubmed ID: 19139169 Sequence Independent Interferon-alpha Induction by Multimerized Phosphodiester DNA Depends on Spatial Regulation of Toll-like Receptor-9 Activation in Plasmacytoid Dendritic Cells Immunology. Feb, 2009 | Pubmed ID: 19019086 Zinc Signals Are Essential for Lipopolysaccharide-induced Signal Transduction in Monocytes Journal of Immunology (Baltimore, Md. : 1950). Nov, 2008 | Pubmed ID: 18941240 Mammalian Target of Rapamycin (mTOR) Orchestrates the Defense Program of Innate Immune Cells European Journal of Immunology. Nov, 2008 | Pubmed ID: 18924132 Circumvention of Regulatory CD4(+) T Cell Activity During Cross-priming Strongly Enhances T Cell-mediated Immunity European Journal of Immunology. Jun, 2008 | Pubmed ID: 18465771 The DNA Sugar Backbone 2' Deoxyribose Determines Toll-like Receptor 9 Activation Immunity. Mar, 2008 | Pubmed ID: 18342006 TLR9 Contributes to Antiviral Immunity During Gammaherpesvirus Infection Journal of Immunology (Baltimore, Md. : 1950). Jan, 2008 | Pubmed ID: 18097045 Protective Cancer Immunotherapy: What Can the Innate Immune System Contribute? Expert Opinion on Biological Therapy. Jan, 2008 | Pubmed ID: 18081535 Vaccine Protocols for Enhanced Immunogenicity of Exogenous Antigens International Journal of Medical Microbiology : IJMM. Jan, 2008 | Pubmed ID: 17888726 Polylactide-coglycolide Microspheres Co-encapsulating Recombinant Tandem Prion Protein with CpG-oligonucleotide Break Self-tolerance to Prion Protein in Wild-type Mice and Induce CD4 and CD8 T Cell Responses Journal of Immunology (Baltimore, Md. : 1950). Sep, 2007 | Pubmed ID: 17709493 Antigen Co-encapsulated with Adjuvants Efficiently Drive Protective T Cell Immunity European Journal of Immunology. Aug, 2007 | Pubmed ID: 17628858 NK Cell Activation in Visceral Leishmaniasis Requires TLR9, Myeloid DCs, and IL-12, but is Independent of Plasmacytoid DCs The Journal of Experimental Medicine. Apr, 2007 | Pubmed ID: 17389237 Immunostimulatory RNA is a Potent Inducer of Antigen-specific Cytotoxic and Humoral Immune Response in Vivo International Immunology. Mar, 2007 | Pubmed ID: 17289655 Interferon-regulatory-factor 1 Controls Toll-like Receptor 9-mediated IFN-beta Production in Myeloid Dendritic Cells European Journal of Immunology. Feb, 2007 | Pubmed ID: 17273999 CpG Motif-independent Activation of TLR9 Upon Endosomal Translocation of "natural" Phosphodiester DNA European Journal of Immunology. Feb, 2006 | Pubmed ID: 16421948 Systemic Application of CpG-rich DNA Suppresses Adaptive T Cell Immunity Via Induction of IDO European Journal of Immunology. Jan, 2006 | Pubmed ID: 16323249 Endosomal Translocation of Vertebrate DNA Activates Dendritic Cells Via TLR9-dependent and -independent Pathways Journal of Immunology (Baltimore, Md. : 1950). May, 2005 | Pubmed ID: 15879108 Protective CD8 T Cell Immunity Triggered by CpG-protein Conjugates Competes with the Efficacy of Live Vaccines Journal of Immunology (Baltimore, Md. : 1950). Apr, 2005 | Pubmed ID: 15778402 Requirement for TLR9 in the Immunomodulatory Activity of Propionibacterium Acnes Journal of Immunology (Baltimore, Md. : 1950). Apr, 2005 | Pubmed ID: 15778393 Targeting Split Vaccines to the Endosome Improves Vaccination Current Opinion in Biotechnology. Dec, 2004 | Pubmed ID: 15560980 Transcriptional Activation Induced in Macrophages by Toll-like Receptor (TLR) Ligands: from Expression Profiling to a Model of TLR Signaling European Journal of Immunology. Oct, 2004 | Pubmed ID: 15368303 CpG-DNA Aided Cross-priming by Cross-presenting B Cells Journal of Immunology (Baltimore, Md. : 1950). Feb, 2004 | Pubmed ID: 14734727 Vaccination with Plasmid DNA Activates Dendritic Cells Via Toll-like Receptor 9 (TLR9) but Functions in TLR9-deficient Mice Journal of Immunology (Baltimore, Md. : 1950). Dec, 2003 | Pubmed ID: 14634101 Cutting Edge: Toll-like Receptor 9 Expression is Not Required for CpG DNA-aided Cross-presentation of DNA-conjugated Antigens but Essential for Cross-priming of CD8 T Cells Journal of Immunology (Baltimore, Md. : 1950). Mar, 2003 | Pubmed ID: 12626528 CpG-DNA Aided Cross-presentation of Soluble Antigens by Dendritic Cells European Journal of Immunology. Aug, 2002 | Pubmed ID: 12209649 Enumeration of Major Peripheral Blood Leukocyte Populations for Multicenter Clinical Trials Using a Whole Blood Phenotyping Assay Tiffany R. Hensley1, Austin B. Easter1, Sarah E. Gerdts1, Stephen C. De Rosa1, Antje Heit1, M. Juliana McElrath1, Erica Andersen-Nissen1 1Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center JoVE 4302 Immunology and Infection
Enumeration of Major Peripheral Blood Leukocyte Populations for Multicenter Clinical Trials Using a Whole Blood Phenotyping Assay Tiffany R. Hensley1, Austin B. Easter1, Sarah E. Gerdts1, Stephen C. De Rosa1, Antje Heit1, M. Juliana McElrath1, Erica Andersen-Nissen1 1Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center JoVE 4302 Immunology and Infection
