Articles by Anton Axelsson in JoVE
Síntesis altamente estereoselectiva de 1,6-cetoésteres Mediada por líquidos iónicos: una reacción de tres componentes Habilitación de acceso rápido a una nueva clase de bajo peso molecular gelificantes Henrik Sundén1, Linda Ta1, Anton Axelsson1 1Chemistry and Chemical Engineering, Chalmers University of Technology
Other articles by Anton Axelsson on PubMed
Ionic Liquids As Precatalysts in the Highly Stereoselective Conjugate Addition of α,β-unsaturated Aldehydes to Chalcones Chemistry (Weinheim an Der Bergstrasse, Germany). Oct, 2014 | Pubmed ID: 25201607 Imidazolium-based ionic liquids (ILs) serve both as recyclable reaction media and as precatalysts for the N-heterocyclic carbene-catalyzed conjugate addition of α,β-unsaturated aldehydes to chalcones. The reaction produces a broad scope of 1,6-ketoesters incorporating an anti-diphenyl moiety in high yields and with high stereoselectivity. In recycling experiments, the IL can be reused up to five times with retained reactivity and selectivity. Moreover, the 1,6-ketoesters form self-assembled organogels in aliphatic hydrocarbons. The reaction protocol is robust, easily operated, scalable and highly functionalized compounds can be obtained from inexpensive and readily accessible starting materials.