Antonio Bedalov Division of Clinical Research Fred Hutchinson Cancer Research Center Biography Publications Institution JoVE Articles Antonio Bedalov has not added a biography. If you are Antonio Bedalov and would like to personalize this page please email our Author Liaison for assistance. Publications Screen for Reactivation of MeCP2 on the Inactive X Chromosome Identifies the BMP/TGF-β Superfamily As a Regulator of XIST Expression Proceedings of the National Academy of Sciences of the United States of America. Feb, 2017 | Pubmed ID: 28143937 SIR2 Suppresses Replication Gaps and Genome Instability by Balancing Replication Between Repetitive and Unique Sequences Proceedings of the National Academy of Sciences of the United States of America. Jan, 2017 | Pubmed ID: 28049846 A High-throughput Small Molecule Screen Identifies Synergism Between DNA Methylation and Aurora Kinase Pathways for X Reactivation Proceedings of the National Academy of Sciences of the United States of America. Dec, 2016 | Pubmed ID: 28182563 Wild-type Microglia Do Not Reverse Pathology in Mouse Models of Rett Syndrome Nature. May, 2015 | Pubmed ID: 25993969 The Androgen-regulated Protease TMPRSS2 Activates a Proteolytic Cascade Involving Components of the Tumor Microenvironment and Promotes Prostate Cancer Metastasis Cancer Discovery. Nov, 2014 | Pubmed ID: 25122198 Development of Pyrazolone and Isoxazol-5-one Cambinol Analogues As Sirtuin Inhibitors Journal of Medicinal Chemistry. Apr, 2014 | Pubmed ID: 24697269 Enterocyte-specific Inactivation of SIRT1 Reduces Tumor Load in the APC(+/min) Mouse Model PloS One. 2013 | Pubmed ID: 23799088 A Natural Polymorphism in RDNA Replication Origins Links Origin Activation with Calorie Restriction and Lifespan PLoS Genetics. 2013 | Pubmed ID: 23505383 Proteomic Classification of Acute Leukemias by Alignment-based Quantitation of LC-MS/MS Data Sets Journal of Proteome Research. Oct, 2012 | Pubmed ID: 22900933 SIRT1 is Dispensable for Function of Hematopoietic Stem Cells in Adult Mice Blood. Feb, 2012 | Pubmed ID: 22219225 C. Elegans와 초파리에서 수명에 Sir2 Overexpression의 효과의 부재 Nature. Sep, 2011 | Pubmed ID: 21938067 Genetic Variation Shapes Protein Networks Mainly Through Non-transcriptional Mechanisms PLoS Biology. Sep, 2011 | Pubmed ID: 21909241 Natural Polymorphism in BUL2 Links Cellular Amino Acid Availability with Chronological Aging and Telomere Maintenance in Yeast PLoS Genetics. Aug, 2011 | Pubmed ID: 21901113 Sirtuin Modulators Handbook of Experimental Pharmacology. 2011 | Pubmed ID: 21879453 Treosulfan와 Fludarabine 고 위험도 혈액 악성 종양에 대 한 수용자 조 혈 모 세포 이식 뒤 컨디셔닝 Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation. Mar, 2011 | Pubmed ID: 20685259 Identification of Inhibitors of Chromatin Modifying Enzymes Using the Yeast Phenotypic Screens Methods in Molecular Biology (Clifton, N.J.). 2009 | Pubmed ID: 19521823 Intracellular NAD Levels Regulate Tumor Necrosis Factor Protein Synthesis in a Sirtuin-dependent Manner Nature Medicine. Feb, 2009 | Pubmed ID: 19151729 Identification and Characterization of Small-molecule Inhibitors of Hepsin Molecular Cancer Therapeutics. Oct, 2008 | Pubmed ID: 18852137 녹 농 균 Exoenzyme 효 모 Phenotypic 화면을 사용 하 여 S의 작은 분자 억제제의 식별 PLoS Genetics. Feb, 2008 | Pubmed ID: 18454192 Hst3 is Regulated by Mec1-dependent Proteolysis and Controls the S Phase Checkpoint and Sister Chromatid Cohesion by Deacetylating Histone H3 at Lysine 56 The Journal of Biological Chemistry. Dec, 2007 | Pubmed ID: 17977840 Genetic Basis of Proteome Variation in Yeast Nature Genetics. Nov, 2007 | Pubmed ID: 17952072 Hematopoietic Cell Transplantation in Patients with Myelodysplastic Syndrome or Acute Myeloid Leukemia Arising from Myelodysplastic Syndrome: Similar Outcomes in Patients with De Novo Disease and Disease Following Prior Therapy or Antecedent Hematologic Disorders Blood. Aug, 2007 | Pubmed ID: 17488876 Pharmacogenetics: Yeast Lead the Way Chemistry & Biology. Mar, 2006 | Pubmed ID: 16638528 Antitumor Activity of a Small-molecule Inhibitor of Human Silent Information Regulator 2 Enzymes Cancer Research. Apr, 2006 | Pubmed ID: 16618762 Telomere Length As a Quantitative Trait: Genome-wide Survey and Genetic Mapping of Telomere Length-control Genes in Yeast PLoS Genetics. Mar, 2006 | Pubmed ID: 16552446 Identification and Characterization of Sir2 Inhibitors Through Phenotypic Assays in Yeast Combinatorial Chemistry & High Throughput Screening. Nov, 2004 | Pubmed ID: 15578928 Neuroscience. NAD to the Rescue Science (New York, N.Y.). Aug, 2004 | Pubmed ID: 15310883 Yeast As a Model System for Anticancer Drug Discovery Nature Reviews. Cancer. 06, 2004 | Pubmed ID: 15170450 Inhibitors of Sir2: Evaluation of Splitomicin Analogues Journal of Medicinal Chemistry. May, 2004 | Pubmed ID: 15115404 Identification of Selective Inhibitors of NAD+-dependent Deacetylases Using Phenotypic Screens in Yeast The Journal of Biological Chemistry. Dec, 2003 | Pubmed ID: 14534292 NAD+-dependent Deacetylase Hst1p Controls Biosynthesis and Cellular NAD+ Levels in Saccharomyces Cerevisiae Molecular and Cellular Biology. Oct, 2003 | Pubmed ID: 12972620 Sir2 Flexes Its Muscle Developmental Cell. Aug, 2003 | Pubmed ID: 12919668 Identification of a Small Molecule Inhibitor of Sir2p Proceedings of the National Academy of Sciences of the United States of America. Dec, 2001 | Pubmed ID: 11752457 G2-seq: 높은 처리량 시퀀싱 기반 기술을 늦게 게놈의 복제 확인 Eric J. Foss1, Uyen Lao1, Antonio Bedalov1,2 1Division of Clinical Research, Fred Hutchinson Cancer Research Center, 2Departments of Medicine and Biochemistry, University of Washington JoVE 56286 Genetics 풀링된 shRNA MeCP2 재 활성화 비활성화 X 염색체에 대 한 화면 Vid Leko1,2, Smitha Sripathy1, Robin L. Adrianse1, Taylor Loe1, Angela Park1, Uyen Lao1, Eric J. Foss1, Marisa S. Bartolomei3, Antonio Bedalov1,4 1Clinical Research Division, Fred Hutchinson Cancer Research Center, 2Hematology Branch, National Heart, Lung and Blood Institute, National Institutes of Health, 3Epigenetics Program, Department of Cell and Developmental Biology, University of Pennsylvania Perelman School of Medicine, 4Departments of Medicine and Biochemistry, University of Washington JoVE 56398 Genetics
G2-seq: 높은 처리량 시퀀싱 기반 기술을 늦게 게놈의 복제 확인 Eric J. Foss1, Uyen Lao1, Antonio Bedalov1,2 1Division of Clinical Research, Fred Hutchinson Cancer Research Center, 2Departments of Medicine and Biochemistry, University of Washington JoVE 56286 Genetics
풀링된 shRNA MeCP2 재 활성화 비활성화 X 염색체에 대 한 화면 Vid Leko1,2, Smitha Sripathy1, Robin L. Adrianse1, Taylor Loe1, Angela Park1, Uyen Lao1, Eric J. Foss1, Marisa S. Bartolomei3, Antonio Bedalov1,4 1Clinical Research Division, Fred Hutchinson Cancer Research Center, 2Hematology Branch, National Heart, Lung and Blood Institute, National Institutes of Health, 3Epigenetics Program, Department of Cell and Developmental Biology, University of Pennsylvania Perelman School of Medicine, 4Departments of Medicine and Biochemistry, University of Washington JoVE 56398 Genetics
