Ari M. Melnick Department of Medicine Weill Cornell Medical College Biography Publications Institution JoVE Articles Ari M. Melnick has not added a biography. If you are Ari M. Melnick and would like to personalize this page please email our Author Liaison for assistance. Publications The H3K27me3 Demethylase UTX is a Gender-specific Tumor Suppressor in T-cell Acute Lymphoblastic Leukemia Blood. Jan, 2015 | Pubmed ID: 25320243 Deep Sequencing Reveals Clonal Evolution Patterns and Mutation Events Associated with Relapse in B-cell Lymphomas Genome Biology. 2014 | Pubmed ID: 25123191 Histone Deacetylase Inhibitor Treatment Induces 'BRCAness' and Synergistic Lethality with PARP Inhibitor and Cisplatin Against Human Triple Negative Breast Cancer Cells Oncotarget. Jul, 2014 | Pubmed ID: 25026298 Hematopoietic Stem Cell Origin of BRAFV600E Mutations in Hairy Cell Leukemia Science Translational Medicine. May, 2014 | Pubmed ID: 24871132 Mechanistic Rationale for Targeting the Unfolded Protein Response in Pre-B Acute Lymphoblastic Leukemia Proceedings of the National Academy of Sciences of the United States of America. May, 2014 | Pubmed ID: 24821775 Differentiation Therapy for IDH1/2 Mutant Malignancies Cell Research. Aug, 2013 | Pubmed ID: 23732524 New Effector Functions and Regulatory Mechanisms of BCL6 in Normal and Malignant Lymphocytes Current Opinion in Immunology. Jun, 2013 | Pubmed ID: 23725655 EZH2 is Required for Germinal Center Formation and Somatic EZH2 Mutations Promote Lymphoid Transformation Cancer Cell. May, 2013 | Pubmed ID: 23680150 BCL6 Breaks Occur at Different AID Sequence Motifs in Ig-BCL6 and Non-Ig-BCL6 Rearrangements Blood. May, 2013 | Pubmed ID: 23476051 Notch Activation Inhibits AML Growth and Survival: a Potential Therapeutic Approach The Journal of Experimental Medicine. Feb, 2013 | Pubmed ID: 23359069 Epigenetic Repression of MiR-31 Disrupts Androgen Receptor Homeostasis and Contributes to Prostate Cancer Progression Cancer Research. Feb, 2013 | Pubmed ID: 23233736 Methylome Profiling Reveals Distinct Alterations in Phenotypic and Mutational Subgroups of Myeloproliferative Neoplasms Cancer Research. Feb, 2013 | Pubmed ID: 23066032 Negative Regulation of Osteoclast Precursor Differentiation by CD11b and β2 Integrin-B-cell Lymphoma 6 Signaling Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. Jan, 2013 | Pubmed ID: 22893614 Integrative Epigenomic Analysis Identifies Biomarkers and Therapeutic Targets in Adult B-acute Lymphoblastic Leukemia Cancer Discovery. Nov, 2012 | Pubmed ID: 23107779 Genome-wide Detection of Genes Targeted by Non-Ig Somatic Hypermutation in Lymphoma PloS One. 2012 | Pubmed ID: 22808135 Oncogene-mediated Alterations in Chromatin Conformation Proceedings of the National Academy of Sciences of the United States of America. Jun, 2012 | Pubmed ID: 22615383 The Bcl6-SMRT/NCoR Cistrome Represses Inflammation to Attenuate Atherosclerosis Cell Metabolism. Apr, 2012 | Pubmed ID: 22465074 SYK Inhibition and Response Prediction in Diffuse Large B-cell Lymphoma Blood. Dec, 2011 | Pubmed ID: 22025527 BCL6-mediated Repression of P53 is Critical for Leukemia Stem Cell Survival in Chronic Myeloid Leukemia The Journal of Experimental Medicine. Oct, 2011 | Pubmed ID: 21911423 Epigenetics in AML Best Practice & Research. Clinical Haematology. Dec, 2010 | Pubmed ID: 21130408 EZH2-mediated Epigenetic Silencing in Germinal Center B Cells Contributes to Proliferation and Lymphomagenesis Blood. Dec, 2010 | Pubmed ID: 20736451 BCL6 is Critical for the Development of a Diverse Primary B Cell Repertoire The Journal of Experimental Medicine. Jun, 2010 | Pubmed ID: 20498019 Derepression in the Desert: the Third Workshop on Clinical Translation of Epigenetics in Cancer Therapeutics Cancer Research. Jul, 2008 | Pubmed ID: 18593891 The Theoretical Basis of Transcriptional Therapy of Cancer: Can It Be Put into Practice? Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Jun, 2005 | Pubmed ID: 15867201 The Flt3 Internal Tandem Duplication Mutant Inhibits the Function of Transcriptional Repressors by Blocking Interactions with SMRT Blood. Jun, 2004 | Pubmed ID: 14982881 VDJ-Sec: Análisis de secuenciación profunda del gen de la cadena pesada de inmunoglobulina reordenados para revelar clonal Evolución Patrones de linfoma de células B Yanwen Jiang1,2, Kui Nie3, David Redmond2, Ari M. Melnick1, Wayne Tam3, Olivier Elemento2 1Department of Medicine, Weill Cornell Medical College, 2Institute for Computational Biomedicine, Weill Cornell Medical College, 3Department of Pathology and Laboratory Medicine, Weill Cornell Medical College Medicine Enhanced reducido Representación bisulfito secuenciación para la Evaluación de la metilación del ADN en la Resolución Base Par Francine E. Garrett-Bakelman*1, Caroline K. Sheridan*1, Thadeous J. Kacmarczyk1, Jennifer Ishii1, Doron Betel1,2, Alicia Alonso1, Christopher E. Mason3, Maria E. Figueroa4, Ari M. Melnick1 1Department of Medicine, Weill Cornell Medical College, 2Institute for Computational Biomedicine, Weill Cornell Medical College, 3Department of Physiology and Biophysics, Weill Cornell Medical College, 4Department of Pathology, University of Michigan Biology
VDJ-Sec: Análisis de secuenciación profunda del gen de la cadena pesada de inmunoglobulina reordenados para revelar clonal Evolución Patrones de linfoma de células B Yanwen Jiang1,2, Kui Nie3, David Redmond2, Ari M. Melnick1, Wayne Tam3, Olivier Elemento2 1Department of Medicine, Weill Cornell Medical College, 2Institute for Computational Biomedicine, Weill Cornell Medical College, 3Department of Pathology and Laboratory Medicine, Weill Cornell Medical College Medicine
Enhanced reducido Representación bisulfito secuenciación para la Evaluación de la metilación del ADN en la Resolución Base Par Francine E. Garrett-Bakelman*1, Caroline K. Sheridan*1, Thadeous J. Kacmarczyk1, Jennifer Ishii1, Doron Betel1,2, Alicia Alonso1, Christopher E. Mason3, Maria E. Figueroa4, Ari M. Melnick1 1Department of Medicine, Weill Cornell Medical College, 2Institute for Computational Biomedicine, Weill Cornell Medical College, 3Department of Physiology and Biophysics, Weill Cornell Medical College, 4Department of Pathology, University of Michigan Biology
