Armand Keating Laboratory Medicine and Pathobiology, Temerty Faculty of Medicine University of Toronto Biography Publications Institution JoVE Articles Armand Keating has not added a biography. If you are Armand Keating and would like to personalize this page please email our Author Liaison for assistance. Publications Pancreatic Cancer Growth Promoted by Bone Marrow Mesenchymal Stromal Cell-derived IL-6 is Reversed Predominantly by IL-6 Blockade Cytotherapy. Jul, 2022 | Pubmed ID: 35473998 Treatment of COVID-19 with MSCs: How Does It Work? Science China. Life Sciences. 04, 2022 | Pubmed ID: 34755253 Prodrugs and Prodrug-activated Systems in Gene Therapy Molecular Therapy : the Journal of the American Society of Gene Therapy. 05, 2021 | Pubmed ID: 33831557 Lentivirus-mediated Gene Therapy for Fabry Disease Nature Communications. 02, 2021 | Pubmed ID: 33633114 Hydrogen Peroxide-Induced Senescence Reduces the Wound Healing-Promoting Effects of Mesenchymal Stem Cell-Derived Exosomes Partially Via MiR-146a Aging and Disease. Feb, 2021 | Pubmed ID: 33532131 Immunophenotypic Characterization and Therapeutics Effects of Human Bone Marrow- and Umbilical Cord-derived Mesenchymal Stromal Cells in an Experimental Model of Sepsis Experimental Cell Research. 02, 2021 | Pubmed ID: 33428902 Killer Immunoglobulin-Like Receptor-Ligand Interactions Predict Clinical Outcomes Following Unrelated Donor Transplantations Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation. 04, 2020 | Pubmed ID: 31676338 Banking Mesenchymal Stromal Cells from Umbilical Cord Tissue: Large Sample Size Analysis Reveals Consistency Between Donors Stem Cells Translational Medicine. 10, 2019 | Pubmed ID: 31219684 Exosomes Secreted by Mesenchymal Stromal/stem Cell-derived Adipocytes Promote Breast Cancer Cell Growth Via Activation of Hippo Signaling Pathway Stem Cell Research & Therapy. 04, 2019 | Pubmed ID: 30971292 Bone Marrow Mesenchymal Stromal Cell Treatment in Patients with Osteoarthritis Results in Overall Improvement in Pain and Symptoms and Reduces Synovial Inflammation Stem Cells Translational Medicine. 08, 2019 | Pubmed ID: 30964245 Generation of Functional Hepatocytes from Human Adipose-Derived MYC KLF4 GMNN Stem Cells Analyzed by Single-Cell RNA-Seq Profiling Stem Cells Translational Medicine. 11, 2018 | Pubmed ID: 30272835 Human Mesenchymal Stromal Cells Do Not Promote Recurrence of Soft Tissue Sarcomas in Mouse Xenografts After Radiation and Surgery Cytotherapy. 08, 2018 | Pubmed ID: 30076069 CD16NK-92 and Anti-CD123 Monoclonal Antibody Prolongs Survival in Primary Human Acute Myeloid Leukemia Xenografted Mice Haematologica. 10, 2018 | Pubmed ID: 29976748 Beyond Maximum Grade: Modernising the Assessment and Reporting of Adverse Events in Haematological Malignancies The Lancet. Haematology. Nov, 2018 | Pubmed ID: 29907552 Exosomes Released by Hepatocarcinoma Cells Endow Adipocytes with Tumor-promoting Properties Journal of Hematology & Oncology. 06, 2018 | Pubmed ID: 29898759 Topical Application of Culture-Expanded CD34+ Umbilical Cord Blood Cells from Frozen Units Accelerates Healing of Diabetic Skin Wounds in Mice Stem Cells Translational Medicine. 08, 2018 | Pubmed ID: 29752867 Effectiveness and Tolerability of First-line Autologous Stem Cell Transplant and Maintenance Rituximab for Mantle Cell Lymphoma Bone Marrow Transplantation. 03, 2018 | Pubmed ID: 29269808 Collagen Scaffold Enhances the Regenerative Properties of Mesenchymal Stromal Cells PloS One. 2017 | Pubmed ID: 29088264 Immunomodulatory Properties of : The Role of Polysaccharopeptide Frontiers in Immunology. 2017 | Pubmed ID: 28932226 Lentivector Iterations and Pre-Clinical Scale-Up/Toxicity Testing: Targeting Mobilized CD34 Cells for Correction of Fabry Disease Molecular Therapy. Methods & Clinical Development. Jun, 2017 | Pubmed ID: 28603745 Concise Review: Wharton's Jelly: The Rich, but Enigmatic, Source of Mesenchymal Stromal Cells Stem Cells Translational Medicine. 07, 2017 | Pubmed ID: 28488282 TLR3 or TLR4 Activation Enhances Mesenchymal Stromal Cell-Mediated Treg Induction Via Notch Signaling Stem Cells (Dayton, Ohio). 01, 2017 | Pubmed ID: 27571579 Human Mesenchymal Stromal Cells Improve Cardiac Perfusion in an Ovine Immunocompetent Animal Model Journal of Investigative Surgery : the Official Journal of the Academy of Surgical Research. Aug, 2016 | Pubmed ID: 26891475 A Radiolabeled Antibody Targeting CD123(+) Leukemia Stem Cells - Initial Radioimmunotherapy Studies in NOD/SCID Mice Engrafted with Primary Human AML Leukemia Research Reports. 2015 | Pubmed ID: 26500848 A Prognostic Model Predicting Autologous Transplantation Outcomes in Children, Adolescents and Young Adults with Hodgkin Lymphoma Bone Marrow Transplantation. Nov, 2015 | Pubmed ID: 26237164 Mesenchymal Stromal Cells Improve Cardiac Function and Left Ventricular Remodeling in a Heart Transplantation Model The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation. Nov, 2015 | Pubmed ID: 26234284 Bone Marrow Therapies for Chronic Heart Disease Stem Cells (Dayton, Ohio). Nov, 2015 | Pubmed ID: 26086629 Sca-1+Lin-CD117- Mesenchymal Stem/stromal Cells Induce the Generation of Novel IRF8-controlled Regulatory Dendritic Cells Through Notch-RBP-J Signaling Journal of Immunology (Baltimore, Md. : 1950). May, 2015 | Pubmed ID: 25825436 Therapeutic Properties of Mesenchymal Stem Cells for Autism Spectrum Disorders Medical Hypotheses. Mar, 2015 | Pubmed ID: 25592283 Uterine-derived Stem Cells Reconstitute the Bone Marrow of Irradiated Mice Stem Cells and Development. Apr, 2015 | Pubmed ID: 25434698 Depletion of Bone Marrow CCSP-expressing Cells Delays Airway Regeneration Molecular Therapy : the Journal of the American Society of Gene Therapy. Mar, 2015 | Pubmed ID: 25409745 MicroSPECT/CT Imaging of Primary Human AML Engrafted into the Bone Marrow and Spleen of NOD/SCID Mice Using 111In-DTPA-NLS-CSL360 Radioimmunoconjugates Recognizing the CD123+ / CD131- Epitope Expressed by Leukemia Stem Cells Leukemia Research. Nov, 2014 | Pubmed ID: 25278187 Harmonizing Standards for Producing Clinical-grade Therapies from Pluripotent Stem Cells Nature Biotechnology. Aug, 2014 | Pubmed ID: 25093882 Donor Mesenchymal Stromal Cells (MSCs) Undergo Variable Cardiac Reprogramming in Vivo and Predominantly Co-express Cardiac and Stromal Determinants After Experimental Acute Myocardial Infarction Stem Cell Reviews and Reports. Apr, 2014 | Pubmed ID: 24287730 Rbm47, a Novel RNA Binding Protein, Regulates Zebrafish Head Development Developmental Dynamics : an Official Publication of the American Association of Anatomists. Dec, 2013 | Pubmed ID: 24038582 When the Best is the Enemy of the Good: the Case of Bone-marrow Mononuclear Cells to Treat Ischemic Syndromes Haematologica. Mar, 2013 | Pubmed ID: 23449595 Autologous Blood Cell Transplantation Versus HLA-identical Siblingtransplantation for Acute Myeloid Leukemia in First Complete Remission:a Registry Study from the Center for International Blood and MarrowTransplantation Research Haematologica. Sep, 2012 | Pubmed ID: 22983587 Role of Salvage Radiation Therapy for Patients with Relapsed or Refractory Hodgkin Lymphoma Who Failed Autologous Stem Cell Transplant International Journal of Radiation Oncology, Biology, Physics. Nov, 2012 | Pubmed ID: 22672755 Human Mesenchymal Stromal Cells Improve Scar Thickness Without Enhancing Cardiac Function in a Chronic Ischaemic Heart Failure Model Interactive Cardiovascular and Thoracic Surgery. May, 2012 | Pubmed ID: 22361124 Natural Killer Cell Lines Preferentially Kill Clonogenic Multiple Myeloma Cells and Decrease Myeloma Engraftment in a Bioluminescent Xenograft Mouse Model Haematologica. Jul, 2012 | Pubmed ID: 22271890 Mesenchymal Stromal Cells Mediate a Switch to Alternatively Activated Monocytes/macrophages After Acute Myocardial Infarction Basic Research in Cardiology. Nov, 2011 | Pubmed ID: 21901289 Group V Phospholipase A2 in Bone Marrow-derived Myeloid Cells and Bronchial Epithelial Cells Promotes Bacterial Clearance After Escherichia Coli Pneumonia The Journal of Biological Chemistry. Oct, 2011 | Pubmed ID: 21849511 Dr. Ernest McCulloch Stem Cells and Development. Apr, 2011 | Pubmed ID: 21375409 An Adult Uterine Hemangioblast: Evidence for Extramedullary Self-renewal and Clonal Bilineage Potential Blood. Oct, 2010 | Pubmed ID: 20606165 Rosuvastatin, Identified from a Zebrafish Chemical Genetic Screen for Antiangiogenic Compounds, Suppresses the Growth of Prostate Cancer European Urology. Sep, 2010 | Pubmed ID: 20605315 Clonogenic Assays Measure Leukemia Stem Cell Killing Not Detectable by Chromium Release and Flow Cytometric Cytotoxicity Assays Cytotherapy. Nov, 2010 | Pubmed ID: 20230219 Culture-modified Bone Marrow Cells Attenuate Cardiac and Renal Injury in a Chronic Kidney Disease Rat Model Via a Novel Antifibrotic Mechanism PloS One. Mar, 2010 | Pubmed ID: 20209052 Human Mesenchymal Stem Cells Self-renew and Differentiate According to a Deterministic Hierarchy PloS One. 2009 | Pubmed ID: 19652709 Mesenchymal Stromal Cells As Supportive Cells for Hepatocytes Molecular Therapy : the Journal of the American Society of Gene Therapy. Sep, 2009 | Pubmed ID: 19584815 Allogeneic Hematopoietic Cell Transplantation in Human Immunodeficiency Virus-positive Patients with Hematologic Disorders: a Report from the Center for International Blood and Marrow Transplant Research Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation. Jul, 2009 | Pubmed ID: 19539219 Identification of a Bone Marrow-derived Epithelial-like Population Capable of Repopulating Injured Mouse Airway Epithelium The Journal of Clinical Investigation. Feb, 2009 | Pubmed ID: 19164856 Is There a Role for Autotransplants in AML in First Remission? Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation. Jan, 2009 | Pubmed ID: 19147071 Cell-based Therapies for Osteonecrosis of the Femoral Head Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation. Oct, 2008 | Pubmed ID: 18804037 Intravenously Administered Bone Marrow Cells Migrate to Damaged Brain Tissue and Improve Neural Function in Ischemic Rats Cell Transplantation. 2008 | Pubmed ID: 18351015 Intravenously Administered Bone Marrow Cells Migrate to Damaged Brain Tissue and Improve Neural Function in Ischemic Rats Cell Transplantation. Nov, 2007 | Pubmed ID: 28866928 Local Radiotherapy Induces Homing of Hematopoietic Stem Cells to the Irradiated Bone Marrow Cancer Research. Nov, 2007 | Pubmed ID: 17974951 Immuno-polymeric Nanoparticles by Diels-Alder Chemistry Angewandte Chemie (International Ed. in English). 2007 | Pubmed ID: 17628481 Oligodendrocytes and Radial Glia Derived from Adult Rat Spinal Cord Progenitors: Morphological and Immunocytochemical Characterization The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. Mar, 2007 | Pubmed ID: 17101728 Preparing for the Unthinkable: Emergency Preparedness for the Hematopoietic Cell Transplant Program Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation. Nov, 2006 | Pubmed ID: 17085317 Mesenchymal Stromal Cells Current Opinion in Hematology. Nov, 2006 | Pubmed ID: 17053453 Cardioprotective C-kit+ Cells Are from the Bone Marrow and Regulate the Myocardial Balance of Angiogenic Cytokines The Journal of Clinical Investigation. Jul, 2006 | Pubmed ID: 16823487 A Phase II Study of Thalidomide and Vinblastine for Palliative Patients with Hodgkin's Lymphoma Hematology (Amsterdam, Netherlands). Feb, 2006 | Pubmed ID: 16522545 Biomarkers of Potential Prognostic Significance in Diffuse Large B-cell Lymphoma Cancer. Jan, 2006 | Pubmed ID: 16342164 Acute Promyelocytic Leukemia: a Case-based Review Hematology (Amsterdam, Netherlands). Apr, 2003 | Pubmed ID: 12745660 Autologous Stem Cell Transplant for Relapsed and Refractory Peripheral T-cell Lymphoma: Variable Outcome According to Pathological Subtype British Journal of Haematology. Mar, 2003 | Pubmed ID: 12648067 The Autologous Blood and Marrow Transplant Long-term Follow-up Clinic: a Model of Care for Following and Treating Survivors of Autotransplant Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer. Apr, 2002 | Pubmed ID: 11904790 Culturing Lymphocytes in Simulated Microgravity Using a Rotary Cell Culture System Marieke de Korte1,2, Armand Keating1,2,4, Chen Wang1,3 1Laboratory Medicine and Pathobiology, Temerty Faculty of Medicine, University of Toronto, 2Krembil Research Institute, Toronto Western Hospital, University Health Network, 3Pathology and Lab Medicine, Hematopathology, Mount Sinai Hospital, Sinai Health Systems, 4Medical Oncology and Hematology, Princess Margaret Cancer Centre JoVE 63296 Immunology and Infection
Culturing Lymphocytes in Simulated Microgravity Using a Rotary Cell Culture System Marieke de Korte1,2, Armand Keating1,2,4, Chen Wang1,3 1Laboratory Medicine and Pathobiology, Temerty Faculty of Medicine, University of Toronto, 2Krembil Research Institute, Toronto Western Hospital, University Health Network, 3Pathology and Lab Medicine, Hematopathology, Mount Sinai Hospital, Sinai Health Systems, 4Medical Oncology and Hematology, Princess Margaret Cancer Centre JoVE 63296 Immunology and Infection
