Arthur E. Warrington Department of Neurology Mayo Clinic Biography Publications Institution JoVE Articles Arthur E. Warrington has not added a biography. If you are Arthur E. Warrington and would like to personalize this page please email our Author Liaison for assistance. Publications A Monoclonal Natural Human IgM Protects Axons in the Absence of Remyelination Journal of Neuroinflammation. 2016 | Pubmed ID: 27126523 Recent Advances in Monoclonal Antibody Therapies for Multiple Sclerosis Expert Opinion on Biological Therapy. Jun, 2016 | Pubmed ID: 26914737 Antiviral Protection Via RdRP-Mediated Stable Activation of Innate Immunity PLoS Pathogens. Dec, 2015 | Pubmed ID: 26633895 Antibody-Mediated Oligodendrocyte Remyelination Promotes Axon Health in Progressive Demyelinating Disease Molecular Neurobiology. Sep, 2015 | Pubmed ID: 26409478 Naturally Occurring Monoclonal Antibodies and Their Therapeutic Potential for Neurologic Diseases JAMA Neurology. Nov, 2015 | Pubmed ID: 26389734 A Natural Human IgM That Binds to Gangliosides is Therapeutic in Murine Models of Amyotrophic Lateral Sclerosis Disease Models & Mechanisms. Aug, 2015 | Pubmed ID: 26035393 A Single Dose of a Neuron-binding Human Monoclonal Antibody Improves Brainstem NAA Concentrations, a Biomarker for Density of Spinal Cord Axons, in a Model of Progressive Multiple Sclerosis Journal of Neuroinflammation. 2015 | Pubmed ID: 25924771 Polysialic Acid As an Antigen for Monoclonal Antibody HIgM12 to Treat Multiple Sclerosis and Other Neurodegenerative Disorders Journal of Neurochemistry. Sep, 2015 | Pubmed ID: 25866077 Quantitative PCR Analysis of DNA Aptamer Pharmacokinetics in Mice Nucleic Acid Therapeutics. Feb, 2015 | Pubmed ID: 25536292 Applications of SPR for the Characterization of Molecules Important in the Pathogenesis and Treatment of Neurodegenerative Diseases Expert Review of Neurotherapeutics. Apr, 2014 | Pubmed ID: 24625008 Cellular Targets and Mechanistic Strategies of Remyelination-promoting IgMs As Part of the Naturally Occurring Autoantibody Repertoire Expert Review of Neurotherapeutics. Sep, 2013 | Pubmed ID: 24053345 A Patterned Recombinant Human IgM Guides Neurite Outgrowth of CNS Neurons Scientific Reports. 2013 | Pubmed ID: 23881231 PDGF is Required for Remyelination-promoting IgM Stimulation of Oligodendrocyte Progenitor Cell Proliferation PloS One. 2013 | Pubmed ID: 23383310 Therapeutics to Promote CNS Repair: a Natural Human Neuron-binding IgM Regulates Membrane-raft Dynamics and Improves Motility in a Mouse Model of Multiple Sclerosis Journal of Clinical Immunology. Jan, 2013 | Pubmed ID: 22990667 Naturally Occurring Antibodies As Therapeutics for Neurologic Disease: Can Human Monoclonal IgMs Replace the Limited Resource IVIG? Advances in Experimental Medicine and Biology. 2012 | Pubmed ID: 22903665 High-affinity Binding of Remyelinating Natural Autoantibodies to Myelin-mimicking Lipid Bilayers Revealed by Nanohole Surface Plasmon Resonance Analytical Chemistry. Jul, 2012 | Pubmed ID: 22762372 Remyelination Induced by a DNA Aptamer in a Mouse Model of Multiple Sclerosis PloS One. 2012 | Pubmed ID: 22761835 Need for a Paradigm Shift in Therapeutic Approaches to CNS Injury Expert Review of Neurotherapeutics. Apr, 2012 | Pubmed ID: 22449213 A Single Dose of Neuron-binding Human Monoclonal Antibody Improves Spontaneous Activity in a Murine Model of Demyelination PloS One. 2011 | Pubmed ID: 22022490 Evidence for the Role of B Cells and Immunoglobulins in the Pathogenesis of Multiple Sclerosis Neurology Research International. 2011 | Pubmed ID: 21961063 Facile Assembly of Micro- and Nanoarrays for Sensing with Natural Cell Membranes ACS Nano. Sep, 2011 | Pubmed ID: 21842844 A Human IgM Signals Axon Outgrowth: Coupling Lipid Raft to Microtubules Journal of Neurochemistry. Oct, 2011 | Pubmed ID: 21824142 Enhancing CNS Repair in Neurological Disease: Challenges Arising from Neurodegeneration and Rewiring of the Network CNS Drugs. Jul, 2011 | Pubmed ID: 21699269 Autoantibodies with Enzymatic Properties in Human Autoimmune Diseases Journal of Autoimmunity. Sep, 2011 | Pubmed ID: 21624820 The Relevance of Animal Models in Multiple Sclerosis Research Pathophysiology : the Official Journal of the International Society for Pathophysiology / ISP. Feb, 2011 | Pubmed ID: 20537877 Method of Identifying Natural Antibodies for Remyelination Journal of Clinical Immunology. May, 2010 | Pubmed ID: 20387101 Importance of Oligodendrocyte Protection, BBB Breakdown and Inflammation for Remyelination Expert Review of Neurotherapeutics. Mar, 2010 | Pubmed ID: 20187865 Cellular Mechanisms of Central Nervous System Repair by Natural Autoreactive Monoclonal Antibodies Archives of Neurology. Dec, 2009 | Pubmed ID: 20008649 Plasmonic Nanohole Arrays for Label-free Kinetic Biosensing in a Lipid Membrane Environment Conference Proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference. 2009 | Pubmed ID: 19963504 Surface Plasmon Resonance for High-throughput Ligand Screening of Membrane-bound Proteins Biotechnology Journal. Nov, 2009 | Pubmed ID: 19918786 Invited Article: Human Natural Autoantibodies in the Treatment of Neurologic Disease Neurology. Apr, 2009 | Pubmed ID: 19349608 A Recombinant Human IgM Promotes Myelin Repair After a Single, Very Low Dose Journal of Neuroscience Research. Apr, 2007 | Pubmed ID: 17304578 STAT4- and STAT6-signaling Molecules in a Murine Model of Multiple Sclerosis FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Feb, 2006 | Pubmed ID: 16352646 A Human Antibody That Promotes Remyelination Enters the CNS and Decreases Lesion Load As Detected by T2-weighted Spinal Cord MRI in a Virus-induced Murine Model of MS FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Oct, 2004 | Pubmed ID: 15319372 Neuron-binding Human Monoclonal Antibodies Support Central Nervous System Neurite Extension Journal of Neuropathology and Experimental Neurology. May, 2004 | Pubmed ID: 15198125 Antiapoptotische Signalisierung Durch Eine Remyelinisierung-Förderung Der Menschlichen Antimyelin Antikörper Neurobiology of Disease. Feb, 2004 | Pubmed ID: 14751777 Menschliche Monoklonale IgM-Antikörper Fördert ZNS-Myelin-Reparatur Unabhängig Von Fc-Funktion Brain Pathology (Zurich, Switzerland). Oct, 2003 | Pubmed ID: 14655764 Remyelination-promoting Antibodies Activate Distinct Ca2+ Influx Pathways in Astrocytes and Oligodendrocytes: Relationship to the Mechanism of Myelin Repair Molecular and Cellular Neurosciences. Jan, 2003 | Pubmed ID: 12595235 Direct Evidence That a Human Antibody Derived from Patient Serum Can Promote Myelin Repair in a Mouse Model of Chronic-progressive Demyelinating Disease FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Aug, 2002 | Pubmed ID: 12154009 Antikörper Bindungsspezifität für Kappa (V & kgr;) Leichte Kette enthaltende Human (IgM) Antikörper: Polysialinsäure (PSA) An NCAM als Fallstudie Jens O. Watzlawik1,2,3, Robert J. Kahoud1,3,5, Bharath Wootla1,2,3, Meghan M. Painter1,2,3, Arthur E. Warrington1,2,3, William A. Carey3,4, Moses Rodriguez1,2,3 1Department of Neurology, Mayo Clinic, 2Mayo Clinic Center for Multiple Sclerosis and Autoimmune Neurology, Mayo Clinic, 3Center for Regenerative Medicine, Neuroregeneration, Mayo Clinic, 4Division of Neonatal Medicine, Mayo Clinic, 5Department of Pediatric and Adolescent Medicine, Mayo Clinic Immunology and Infection Bildung Biomembrane Microarrays mit einem Rakel-basierten Montageverfahren Nathan J. Wittenberg1, Timothy W. Johnson1, Luke R. Jordan2, Xiaohua Xu3, Arthur E. Warrington3, Moses Rodriguez3,4, Sang-Hyun Oh1,2 1Department of Electrical and Computer Engineering, University of Minnesota, 2Department of Biomedical Engineering, University of Minnesota, 3Department of Neurology, Mayo Clinic College of Medicine, 4Department of Immunology, Mayo Clinic College of Medicine JoVE 51501 Bioengineering
Antikörper Bindungsspezifität für Kappa (V & kgr;) Leichte Kette enthaltende Human (IgM) Antikörper: Polysialinsäure (PSA) An NCAM als Fallstudie Jens O. Watzlawik1,2,3, Robert J. Kahoud1,3,5, Bharath Wootla1,2,3, Meghan M. Painter1,2,3, Arthur E. Warrington1,2,3, William A. Carey3,4, Moses Rodriguez1,2,3 1Department of Neurology, Mayo Clinic, 2Mayo Clinic Center for Multiple Sclerosis and Autoimmune Neurology, Mayo Clinic, 3Center for Regenerative Medicine, Neuroregeneration, Mayo Clinic, 4Division of Neonatal Medicine, Mayo Clinic, 5Department of Pediatric and Adolescent Medicine, Mayo Clinic Immunology and Infection
Bildung Biomembrane Microarrays mit einem Rakel-basierten Montageverfahren Nathan J. Wittenberg1, Timothy W. Johnson1, Luke R. Jordan2, Xiaohua Xu3, Arthur E. Warrington3, Moses Rodriguez3,4, Sang-Hyun Oh1,2 1Department of Electrical and Computer Engineering, University of Minnesota, 2Department of Biomedical Engineering, University of Minnesota, 3Department of Neurology, Mayo Clinic College of Medicine, 4Department of Immunology, Mayo Clinic College of Medicine JoVE 51501 Bioengineering
