Other Publications (1)
Articles by Ashley E. Van Avermaete in JoVE
Real-time X-ray Imaging of Lung Fluid Volumes in Neonatal Mouse Lung Ashley E. Van Avermaete1, Phi T. Trac1, Theresa W. Gauthier1, My N. Helms2 1Department of Pediatrics, Neonatology Division, Emory Children's Center, Emory University, 2Department of Internal Medicine, Pulmonary Division, University of Utah We present a protocol to assess the rate of alveolar fluid clearance or pulmonary edema in neonatal mouse lung using X-ray imaging technology.
Other articles by Ashley E. Van Avermaete on PubMed
Bacterial Infection Probes and Imaging Strategies in Clinical Nuclear Medicine and Preclinical Molecular Imaging Current Topics in Medicinal Chemistry. 2013 | Pubmed ID: 23432010 At present, a limited number of strategies exist for diagnostic imaging of patients with bacterial infection. While radiolabeled probes and white blood cells provide robust solutions to detect bacteria in humans, they also give false positives in cases of sterile inflammation. With the onset of bacterial drug resistance, and a clinical trend toward reducing the prescription of antibiotics, the need for highly specific infection detection protocols has been renewed. The preclinical research community has recently utilized new optical imaging strategies, alongside traditional radioimaging research, to develop novel infection probes with translational potential. Here we review the current clinical methods for imaging bacteria in humans, and discuss the efforts within the preclinical community to validate new strategies. The review of preclinical infection imaging probes is limited to those probes that could be feasibly adapted for use in humans with currently available clinical modalities.