Atsushi Shibata

Publications

• Regulation of Repair Pathway Choice at Two-ended DNA Double-strand Breaks
  Mutation Research. Oct, 2017  |   Pubmed ID: 28781144
• Inhibition of the HDAC/Suv39/G9a Pathway Restores the Expression of DNA Damage-dependent Major Histocompatibility Complex Class I-related Chain A and B in Cancer Cells
  Oncology Reports. Aug, 2017  |   Pubmed ID: 28677817
• A Novel Single-Strand RNAi Therapeutic Agent Targeting the (Pro)renin Receptor Suppresses Ocular Inflammation
  Molecular Therapy. Nucleic Acids. Jun, 2017  |   Pubmed ID: 28624188
• Regulation of Pairing Between Broken DNA-containing Chromatin Regions by Ku80, DNA-PKcs, ATM, and 53BP1
  Scientific Reports. Feb, 2017  |   Pubmed ID: 28155885
• DNA Double-Strand Break Resection Occurs During Non-homologous End Joining in G1 but Is Distinct from Resection During Homologous Recombination
  Molecular Cell. Feb, 2017  |   Pubmed ID: 28132842
• Mitotic Catastrophe is a Putative Mechanism Underlying the Weak Correlation Between Sensitivity to Carbon Ions and Cisplatin
  Scientific Reports. Jan, 2017  |   Pubmed ID: 28091564
• BRCA1 Directs the Repair Pathway to Homologous Recombination by Promoting 53BP1 Dephosphorylation
  Cell Reports. Jan, 2017  |   Pubmed ID: 28076794
• Administration of Tolvaptan with Reduction of Loop Diuretics Ameliorates Congestion with Improving Renal Dysfunction in Patients with Congestive Heart Failure and Renal Dysfunction
  Heart and Vessels. Mar, 2017  |   Pubmed ID: 27385022
• [Pharmacology Profile and Clinical Findings of Bosutinib Hydrate (Bosulif® Tablets)]
  Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica. May, 2016  |   Pubmed ID: 27181728
• Identification of DNA Double Strand Breaks at Chromosome Boundaries Along the Track of Particle Irradiation
  Genes, Chromosomes & Cancer. Aug, 2016  |   Pubmed ID: 27113385
• Exhaled Acetone Concentration Is Related to Hemodynamic Severity in Patients With Non-Ischemic Chronic Heart Failure
  Circulation Journal : Official Journal of the Japanese Circulation Society. Apr, 2016  |   Pubmed ID: 27026173
• Visualization of Complex DNA Double-strand Breaks in a Tumor Treated with Carbon Ion Radiotherapy
  Scientific Reports. Mar, 2016  |   Pubmed ID: 26925533
• A Case of Acute Decompensated Heart Failure Evaluated by Series of Exhaled Acetone Concentrations As Noninvasive Biomarker of Heart Failure Severity
  International Journal of Cardiology. Feb, 2016  |   Pubmed ID: 26655553
• RAD51 and BRCA2 Enhance Oncolytic Adenovirus Type 5 Activity in Ovarian Cancer
  Molecular Cancer Research : MCR. Jan, 2016  |   Pubmed ID: 26452665
• SETDB1, HP1 and SUV39 Promote Repositioning of 53BP1 to Extend Resection During Homologous Recombination in G2 Cells
  Nucleic Acids Research. Sep, 2015  |   Pubmed ID: 26206670
• Carbon-ion Beams Effectively Induce Growth Inhibition and Apoptosis in Human Neural Stem Cells Compared with Glioblastoma A172 Cells
  Journal of Radiation Research. Sep, 2015  |   Pubmed ID: 26070322
• The EGFR Mutation Status Affects the Relative Biological Effectiveness of Carbon-ion Beams in Non-small Cell Lung Carcinoma Cells
  Scientific Reports. Jun, 2015  |   Pubmed ID: 26065573
• Pre-exposure to Ionizing Radiation Stimulates DNA Double Strand Break End Resection, Promoting the Use of Homologous Recombination Repair
  PloS One. 2015  |   Pubmed ID: 25826455
• A Phase 1/2 Study of Bosutinib in Japanese Adults with Philadelphia Chromosome-positive Chronic Myeloid Leukemia
  International Journal of Hematology. Feb, 2015  |   Pubmed ID: 25540064
• Carbon-ion Beam Irradiation Kills X-ray-resistant P53-null Cancer Cells by Inducing Mitotic Catastrophe
  PloS One. 2014  |   Pubmed ID: 25531293
• Impairment of Vesicular ATP Release Affects Glucose Metabolism and Increases Insulin Sensitivity
  Scientific Reports. Oct, 2014  |   Pubmed ID: 25331291
• A Nanocarrier System for the Delivery of Nucleic Acids Targeted to a Pancreatic Beta Cell Line
  Biomaterials. Aug, 2014  |   Pubmed ID: 24816283
• Comprehensive Behavioral Study of MGluR3 Knockout Mice: Implication in Schizophrenia Related Endophenotypes
  Molecular Brain. 2014  |   Pubmed ID: 24758191
• DNA Double-strand Break Repair Pathway Choice is Directed by Distinct MRE11 Nuclease Activities
  Molecular Cell. Jan, 2014  |   Pubmed ID: 24316220
• Molecular Analysis of ATP-sensitive K⁺ Channel Subunits Expressed in Mouse Vas Deferens Myocytes
  British Journal of Pharmacology. Jan, 2014  |   Pubmed ID: 24117345
• Co-operation of BRCA1 and POH1 Relieves the Barriers Posed by 53BP1 and RAP80 to Resection
  Nucleic Acids Research. Dec, 2013  |   Pubmed ID: 24013561
• Opposing Roles for 53BP1 During Homologous Recombination
  Nucleic Acids Research. Nov, 2013  |   Pubmed ID: 23969417
• Visualisation of γH2AX Foci Caused by Heavy Ion Particle Traversal; Distinction Between Core Track Versus Non-track Damage
  PloS One. 2013  |   Pubmed ID: 23967070
• Phase I Study of Sunitinib Plus Modified FOLFOX6 in Japanese Patients with Treatment-naive Colorectal Cancer
  Anticancer Research. Mar, 2012  |   Pubmed ID: 22399619
• Degradation of Flumioxazin in Illuminated Water-sediment Systems
  Journal of Agricultural and Food Chemistry. Oct, 2011  |   Pubmed ID: 21919467
• Analysis of Human Syndromes with Disordered Chromatin Reveals the Impact of Heterochromatin on the Efficacy of ATM-dependent G2/M Checkpoint Arrest
  Molecular and Cellular Biology. Oct, 2011  |   Pubmed ID: 21791604
• Smad2 Protein Disruption in the Central Nervous System Leads to Aberrant Cerebellar Development and Early Postnatal Ataxia in Mice
  The Journal of Biological Chemistry. May, 2011  |   Pubmed ID: 21464123
• Pin-point Chemical Modification of RNA with Diverse Molecules Through the Functionality Transfer Reaction and the Copper-catalyzed Azide-alkyne Cycloaddition Reaction
  Chemical Communications (Cambridge, England). May, 2011  |   Pubmed ID: 21431191
• Genomic DNA Damage and ATR-Chk1 Signaling Determine Oncolytic Adenoviral Efficacy in Human Ovarian Cancer Cells
  The Journal of Clinical Investigation. Apr, 2011  |   Pubmed ID: 21383502
• Factors Determining DNA Double-strand Break Repair Pathway Choice in G2 Phase
  The EMBO Journal. Mar, 2011  |   Pubmed ID: 21317870
• Synthesis and Evaluation of Different Thio-modified Cellulose Resins for the Removal of Mercury (II) Ion from Highly Acidic Aqueous Solutions
  Journal of Colloid and Interface Science. Jan, 2011  |   Pubmed ID: 20974469
• Generation and Characterization of T1R2-LacZ Knock-in Mouse
  Biochemical and Biophysical Research Communications. Nov, 2010  |   Pubmed ID: 20965149
• Sensitization to Radiation and Alkylating Agents by Inhibitors of Poly(ADP-ribose) Polymerase is Enhanced in Cells Deficient in DNA Double-strand Break Repair
  Molecular Cancer Therapeutics. Jun, 2010  |   Pubmed ID: 20530711
• Role of ATM and the Damage Response Mediator Proteins 53BP1 and MDC1 in the Maintenance of G(2)/M Checkpoint Arrest
  Molecular and Cellular Biology. Jul, 2010  |   Pubmed ID: 20421415
• GammaH2AX Foci Analysis for Monitoring DNA Double-strand Break Repair: Strengths, Limitations and Optimization
  Cell Cycle (Georgetown, Tex.). Feb, 2010  |   Pubmed ID: 20139725
• 53BP1-dependent Robust Localized KAP-1 Phosphorylation is Essential for Heterochromatic DNA Double-strand Break Repair
  Nature Cell Biology. Feb, 2010  |   Pubmed ID: 20081839
• Characterization of NaV1.6-mediated Na+ Currents in Smooth Muscle Cells Isolated from Mouse Vas Deferens
  Journal of Cellular Physiology. Apr, 2010  |   Pubmed ID: 20054822
• ATM and Artemis Promote Homologous Recombination of Radiation-induced DNA Double-strand Breaks in G2
  The EMBO Journal. Nov, 2009  |   Pubmed ID: 19779458
• Role of Parp-1 in Suppressing Spontaneous Deletion Mutation in the Liver and Brain of Mice at Adolescence and Advanced Age
  Mutation Research. May, 2009  |   Pubmed ID: 19428377
• [Pharmacology Profile of Sunitinib Malate (Sutent) Capsules) and Clinical Findings on This Drug]
  Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica. Apr, 2009  |   Pubmed ID: 19367024
• Virulence of Mycobacterium Avium Complex Strains Isolated from Immunocompetent Patients
  Microbial Pathogenesis. Jan, 2009  |   Pubmed ID: 19013228
• ATP-sensitive K+ Channels in Pig Urethral Smooth Muscle Cells Are Heteromultimers of Kir6.1 and Kir6.2
  American Journal of Physiology. Renal Physiology. Jan, 2009  |   Pubmed ID: 18945825
• Anaerobic Mineralization of Pentachlorophenol (PCP) by Combining PCP-dechlorinating and Phenol-degrading Cultures
  Biotechnology and Bioengineering. Jan, 2009  |   Pubmed ID: 18683261
• Molecular and Biophysical Properties of Voltage-gated Na+ Channels in Murine Vas Deferens
  Biophysical Journal. Apr, 2008  |   Pubmed ID: 18192366
• Comparative Studies of ZD0947, a Novel ATP-sensitive K(+) Channel Opener, on Guinea Pig Detrusor and Aortic Smooth Muscles
  Naunyn-Schmiedeberg's Archives of Pharmacology. Jan, 2008  |   Pubmed ID: 18071674
• Actions of Two Main Metabolites of Propiverine (M-1 and M-2) on Voltage-dependent L-type Ca2+ Currents and Ca2+ Transients in Murine Urinary Bladder Myocytes
  The Journal of Pharmacology and Experimental Therapeutics. Jan, 2008  |   Pubmed ID: 17928569
• A Novel Expression System for Artificial MiRNAs Containing No Endogenous MiRNA Precursor Sequences
  Journal of RNAi and Gene Silencing : an International Journal of RNA and Gene Targeting Research. May, 2007  |   Pubmed ID: 19771221
• Effect of Temperature on Reaction Rate and Microbial Community in Composting of Cattle Manure with Rice Straw
  Journal of Bioscience and Bioengineering. Oct, 2007  |   Pubmed ID: 18023807
• Effects of Flavoxate Hydrochloride on Voltage-dependent Ba2+ Currents in Human Detrusor Myocytes at Different Experimental Temperatures
  Naunyn-Schmiedeberg's Archives of Pharmacology. Nov, 2007  |   Pubmed ID: 17909749
• The Effect of Calcium Ion on the Biodegradation of Octylphenol Polyethoxylates, and the Antiandrogenic Activity of Their Biodegradates
  Applied Microbiology and Biotechnology. Nov, 2007  |   Pubmed ID: 17786431
• Anaerobic Biodegradation of 4-alkylphenols in a Paddy Soil Microcosm Supplemented with Nitrate
  Chemosphere. Aug, 2007  |   Pubmed ID: 17408723
• Anaerobic Co-metabolic Oxidation of 4-alkylphenols with Medium-length or Long Alkyl Chains by Thauera Sp., Strain R5
  Applied Microbiology and Biotechnology. Jul, 2007  |   Pubmed ID: 17387471
• Increased Leukotriene E4 in the Exhaled Breath Condensate of Children with Mild Asthma
  Chest. Dec, 2006  |   Pubmed ID: 17166987
• Aerobic and Anaerobic Biodegradation of Phenol Derivatives in Various Paddy Soils
  The Science of the Total Environment. Aug, 2006  |   Pubmed ID: 16530810
• Differential Involvement of Phosphatidylinositol 3-kinase-related Protein Kinases in Hyperphosphorylation of Replication Protein A2 in Response to Replication-mediated DNA Double-strand Breaks
  Genes to Cells : Devoted to Molecular & Cellular Mechanisms. Mar, 2006  |   Pubmed ID: 16483312
• Parp-1 Deficiency Causes an Increase of Deletion Mutations and Insertions/rearrangements in Vivo After Treatment with an Alkylating Agent
  Oncogene. Feb, 2005  |   Pubmed ID: 15608683
• Efficient Method for Mapping and Characterizing Structures of Deletion Mutations in Gpt Delta Mice Using Southern Blot Analysis with Oligo DNA Probes
  Environmental and Molecular Mutagenesis. 2004  |   Pubmed ID: 15065208
• Positive Associations of Polymorphisms in the Metabotropic Glutamate Receptor Type 3 Gene (GRM3) with Schizophrenia
  Psychiatric Genetics. Jun, 2003  |   Pubmed ID: 12782962
• Characterization of Biodegradation Intermediates of Nonionic Surfactants by MALDI-MS. 2. Oxidative Biodegradation Profiles of Uniform Octylphenol Polyethoxylate in 18O-labeled Water
  Biomacromolecules. Jan-Feb, 2003  |   Pubmed ID: 12523845
• Positive Association of the AMPA Receptor Subunit GluR4 Gene (GRIA4) Haplotype with Schizophrenia: Linkage Disequilibrium Mapping Using SNPs Evenly Distributed Across the Gene Region
  American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. Jan, 2003  |   Pubmed ID: 12497607
• Association Study of Polymorphisms in the GluR6 Kainate Receptor Gene (GRIK2) with Schizophrenia
  Psychiatry Research. Dec, 2002  |   Pubmed ID: 12467946
• Hypoproteinemia in Severe Childhood Atopic Dermatitis: a Serious Complication
  Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology. Aug, 2002  |   Pubmed ID: 12390445