Basak E. Uygun Shriners Children’s Boston Biography Publications Institution JoVE Articles Basak E. Uygun has not added a biography. If you are Basak E. Uygun and would like to personalize this page please email our Author Liaison for assistance. Publications Tissue Engineering Strategies for Breast Reconstruction: a Literature Review of Current Advances and Future Directions Annals of Translational Medicine. Feb, 2024 | Pubmed ID: 38304901 The Autonomization Principle in Vascularized Flaps: An Alternative Strategy for Composite Tissue Scaffold In Vivo Revascularization Bioengineering (Basel, Switzerland). Dec, 2023 | Pubmed ID: 38136031 Towards Optimizing Sub-Normothermic Machine Perfusion in Fasciocutaneous Flaps: A Large Animal Study Bioengineering (Basel, Switzerland). Dec, 2023 | Pubmed ID: 38136006 Alterations in Cytoskeleton and Mitochondria in the Development and Reversal of Steatosis in Human Hepatocytes Cellular and Molecular Gastroenterology and Hepatology. Apr, 2023 | Pubmed ID: 37085137 Microvascular Assessment of Fascio-cutaneous Flaps by Ultrasound: A Large Animal Study Frontiers in Physiology. 2022 | Pubmed ID: 36589429 Regenerative Medicine Applications: An Overview of Clinical Trials Frontiers in Bioengineering and Biotechnology. 2022 | Pubmed ID: 36507264 Acellular Nipple Scaffold Development, Characterization, and Preliminary Biocompatibility Assessment in a Swine Model Plastic and Reconstructive Surgery. Dec, 2022 | Pubmed ID: 36472499 Human-Origin IPSC-Based Recellularization of Decellularized Whole Rat Livers Bioengineering (Basel, Switzerland). May, 2022 | Pubmed ID: 35621497 Combinatorial Use of Therapeutic ELP-Based Micelle Particles in Tissue Engineering Advanced Healthcare Materials. Jul, 2022 | Pubmed ID: 35373501 Engineering Vascularized Composite Allografts Using Natural Scaffolds: A Systematic Review Tissue Engineering. Part B, Reviews. Jun, 2022 | Pubmed ID: 34238047 Liver Donor Age Affects Hepatocyte Function Through Age-dependent Changes in Decellularized Liver Matrix Biomaterials. Mar, 2021 | Pubmed ID: 33524812 Development of Liver Microtissues with Functional Biliary Ductular Network Biotechnology and Bioengineering. Jan, 2021 | Pubmed ID: 32856740 Tissue Scaffolds Functionalized with Therapeutic Elastin-like Biopolymer Particles Biotechnology and Bioengineering. May, 2020 | Pubmed ID: 31956985 Repopulation of Intrahepatic Bile Ducts in Engineered Rat Liver Grafts Technology. 2019 | Pubmed ID: 31388515 Liver Bioengineering: Promise, Pitfalls, and Hurdles to Overcome Current Transplantation Reports. Jun, 2019 | Pubmed ID: 31289714 Editorial: On Tissue Engineering and Regenerative Medicine of Skin and Its Appendages Frontiers in Physiology. 2019 | Pubmed ID: 31244678 Improving Functional Re-endothelialization of Acellular Liver Scaffold Using REDV Cell-binding Domain Acta Biomaterialia. Sep, 2018 | Pubmed ID: 30071351 Decellularized Human Liver Extracellular Matrix (hDLM)-mediated Hepatic Differentiation of Human Induced Pluripotent Stem Cells (hIPSCs) Journal of Tissue Engineering and Regenerative Medicine. Apr, 2018 | Pubmed ID: 29222839 Preparation of Decellularized Liver Scaffolds and Recellularized Liver Grafts Methods in Molecular Biology (Clifton, N.J.). 2018 | Pubmed ID: 28735385 Co-delivery of a Growth Factor and a Tissue-protective Molecule Using Elastin Biopolymers Accelerates Wound Healing in Diabetic Mice Biomaterials. Oct, 2017 | Pubmed ID: 28688286 Immune Responses to Bioengineered Organs Current Opinion in Organ Transplantation. Feb, 2017 | Pubmed ID: 27926545 Discarded Livers Find a New Life: Engineered Liver Grafts Using Hepatocytes Recovered From Marginal Livers Artificial Organs. Jun, 2017 | Pubmed ID: 27862079 Functionalized Biopolymer Particles Enhance Performance of a Tissue-Protective Peptide Under Proteolytic and Thermal Stress Biomacromolecules. Jun, 2016 | Pubmed ID: 27219509 Nondestructive Methods for Monitoring Cell Removal During Rat Liver Decellularization Tissue Engineering. Part C, Methods. Jul, 2016 | Pubmed ID: 27169332 Rat Liver Regeneration Following Ablation with Irreversible Electroporation PeerJ. 2016 | Pubmed ID: 26819842 Proteomic Analysis of Naturally-sourced Biological Scaffolds Biomaterials. Jan, 2016 | Pubmed ID: 26476196 Layer-by-layer Heparinization of Decellularized Liver Matrices to Reduce Thrombogenicity of Tissue Engineered Grafts Journal of Clinical and Translational Research. Jul, 2015 | Pubmed ID: 30873444 Tissue Heterogeneity in Structure and Conductivity Contribute to Cell Survival During Irreversible Electroporation Ablation by "electric Field Sinks" Scientific Reports. 2015 | Pubmed ID: 25684630 Supercooling Enables Long-term Transplantation Survival Following 4 Days of Liver Preservation Nature Medicine. Jul, 2014 | Pubmed ID: 24973919 SIMPLE MACHINE PERFUSION SIGNIFICANTLY ENHANCES HEPATOCYTE YIELDS OF ISCHEMIC AND FRESH RAT LIVERS Cell Medicine. 2013 | Pubmed ID: 25431743 Supercooling As a Viable Non-freezing Cell Preservation Method of Rat Hepatocytes PloS One. 2013 | Pubmed ID: 23874947 Engineered Liver for Transplantation Current Opinion in Biotechnology. Oct, 2013 | Pubmed ID: 23791465 Application of Whole-organ Tissue Engineering in Hepatology Nature Reviews. Gastroenterology & Hepatology. Dec, 2012 | Pubmed ID: 22890112 Organ Reengineering Through Development of a Transplantable Recellularized Liver Graft Using Decellularized Liver Matrix Nature Medicine. Jul, 2010 | Pubmed ID: 20543851 Cell Delivery: from Cell Transplantation to Organ Engineering Cell Transplantation. 2010 | Pubmed ID: 20525441 Membrane Thickness is an Important Variable in Membrane Scaffolds: Influence of Chitosan Membrane Structure on the Behavior of Cells Acta Biomaterialia. Jun, 2010 | Pubmed ID: 19925888 Retinal Pigment Epithelium Differentiation of Stem Cells: Current Status and Challenges Critical Reviews in Biomedical Engineering. 2009 | Pubmed ID: 20528731 High Throughput Single Cell Bioinformatics Biotechnology Progress. Nov-Dec, 2009 | Pubmed ID: 19830811 Effects of Immobilized Glycosaminoglycans on the Proliferation and Differentiation of Mesenchymal Stem Cells Tissue Engineering. Part A. Nov, 2009 | Pubmed ID: 19456238 Differentiating Stem Cells into Liver Biotechnology & Genetic Engineering Reviews. 2008 | Pubmed ID: 21412354 A Swine Burn Model for Investigating the Healing Process in Multiple Depth Burn Wounds Yanis Berkane1,2,3,4, Rohil Jain2,5, Emmanuella O. Ajenu*2,5, Austin A. Shamlou*1,2, Khanh Nguyen2,5, Michelle McCarthy1,2,5, Basak E. Uygun2,5, Alexandre G. Lellouch1,2,6, Curtis L. Cetrulo Jr.1,2, Korkut Uygun2,5, Mark A. Randolph1,2, Shannon N. Tessier2,5 1Vascularized Composite Allotransplantation Laboratory, Massachusetts General Hospital, Harvard Medical School, 2Shriners Children’s Boston, 3Department of Plastic, Reconstructive and Aesthetic Surgery, Rennes University, 4SITI Laboratory, UMR, INSERM, Université de Rennes, 5Center for Engineering in Medicine and Surgery, Department of Surgery, Massachusetts General Hospital, Harvard Medical School, 6Innovative Therapies in Haemostasis, INSERM UMR-S, University of Paris JoVE 66362 Medicine Author Spotlight: Context Dependent Blood Collection Methods in Rats (Video) | JoVE Laura Charlès1,2,3, Thomas Agius*4,5, Irina Filz von Reiterdank*1,2,3,6, Janna Hagedorn1,2,3, Yanis Berkane1,2,3,7, Hyshem H. Lancia1,2,3, Basak E. Uygun2,3,8, Korkut Uygun2,3,8, Curtis L. Cetrulo Jr.1,2,3,9, Mark A. Randolph1,2,3,9, Alexandre G. Lellouch1,2,3,8 1Vascularized Composite Allotransplantation Laboratory, Massachusetts General Hospital, 2Harvard Medical School, 3Shriners Children’s Boston, 4Center for Engineering in Medicine and Surgery, Massachusetts General Hospital, 5Department of Vascular Surgery, Centre Hospitalier Universitaire Vaudois and University of Lausanne, 6Department of Plastic, Reconstructive and Hand Surgery, University Medical Center Utrecht, 7Department of Plastic, Reconstructive and Aesthetic Surgery, Rennes University Hospital Center (CHU de Rennes), Rennes 1 University, 8Center for Engineering in Medicine and Surgery, Massachusetts General Hospital, 9Plastic Surgery Research Laboratory, Massachusetts General Hospital JoVE 65513 Medicine The Superficial Inferior Epigastric Artery Axial Flap to Study Ischemic Preconditioning Effects in a Rat Model Yanis Berkane*1,2,3,5, Austin Alana Shamlou*1,2,4,5, Jose Reyes1,2, Hyshem H. Lancia1,2,5, Irina Filz von Reiterdank1,2,5,6,7, Nicolas Bertheuil3, Basak E. Uygun2,5,6, Korkut Uygun1,2,5,6, William G. Austen Jr.2,4, Curtis L. Cetrulo Jr.1,2,4,5, Mark A. Randolph1,2,4,5, Alexandre G. Lellouch1,2,5,6,8 1Vascularized Composite Allotransplantation Laboratory, Massachusetts General Hospital, 2Harvard Medical School, 3Department of Plastic, Reconstructive and Aesthetic Surgery, Rennes University Hospital Center (CHU de Rennes), University of Rennes 1, 4Plastic Surgery Research Laboratory, Massachusetts General Hospital, 5Shriners Children's Boston, 6Center for Engineering in Medicine and Surgery, Massachusetts General Hospital, 7Department of Plastic Surgery and Hand Surgery, University Medical Center Utrecht, 8Department of Plastic, Reconstructive, and Aesthetic Surgery, Groupe Almaviva Santé, Clinique de l'Alma JoVE 64980 Immunology and Infection A Reliable Porcine Fascio-Cutaneous Flap Model for Vascularized Composite Allografts Bioengineering Studies Victor Pozzo1,2,4, Golda Romano1,2,4, Marion Goutard1,2,4, Elise Lupon1,2,4, Pierre Tawa1,2,4, Aylin Acun3,4,5, Alec R. Andrews2, Corentin B. Taveau1,2,4,6, Basak E. Uygun1,2,3,4, Mark A. Randolph1,2,4, Curtis L. Cetrulo1,2,4, Alexandre G. Lellouch1,2,4,6 1Division of Plastic and Reconstructive Surgery, Massachusetts General Hospital, Harvard Medical School, 2Vascularized Composite Allotransplantation Laboratory, Center for Transplantation Sciences, Massachusetts General Hospital, Harvard Medical School, 3Center for Engineering in Medicine and Surgery, Massachusetts General Hospital, Harvard Medical School, 4Shriners Hospital for Children, 5Department of Biomedical Engineering, Widener University, 6Service de Chirurgie Plastique, Hôpital Européen Georges Pompidou, Assistance Publique-Hôpitaux de Paris (APHP), Université Paris Descartes JoVE 63557 Bioengineering Functional Human Liver Preservation and Recovery by Means of Subnormothermic Machine Perfusion Bote G. Bruinsma*1, James H. Avruch*2, Pepijn D. Weeder1, Gautham V. Sridharan1, Basak E. Uygun1, Negin G. Karimian1, Robert J. Porte3, James F. Markmann2, Heidi Yeh2, Korkut Uygun1 1Center for Engineering in Medicine, Dept. of Surgery, Massachusetts General Hospital, Harvard Medical School, 2Transplant Center, Dept. of Surgery, Massachusetts General Hospital, Harvard Medical School, 3Section of Hepatobiliary Surgery and Liver Transplantation, Department of Surgery, University Medical Center Groningen, University of Groningen JoVE 52777 Medicine Decellularization and Recellularization of Whole Livers Basak E. Uygun1, Gavrielle Price1, Nima Saeidi1, Maria-Louisa Izamis1, Tim Berendsen1, Martin Yarmush1, Korkut Uygun1 1Center for Engineering in Medicine, Massachusetts General Hospital, Harvard Medical School, Shriners Hospitals for Children JoVE 2394 Bioengineering
A Swine Burn Model for Investigating the Healing Process in Multiple Depth Burn Wounds Yanis Berkane1,2,3,4, Rohil Jain2,5, Emmanuella O. Ajenu*2,5, Austin A. Shamlou*1,2, Khanh Nguyen2,5, Michelle McCarthy1,2,5, Basak E. Uygun2,5, Alexandre G. Lellouch1,2,6, Curtis L. Cetrulo Jr.1,2, Korkut Uygun2,5, Mark A. Randolph1,2, Shannon N. Tessier2,5 1Vascularized Composite Allotransplantation Laboratory, Massachusetts General Hospital, Harvard Medical School, 2Shriners Children’s Boston, 3Department of Plastic, Reconstructive and Aesthetic Surgery, Rennes University, 4SITI Laboratory, UMR, INSERM, Université de Rennes, 5Center for Engineering in Medicine and Surgery, Department of Surgery, Massachusetts General Hospital, Harvard Medical School, 6Innovative Therapies in Haemostasis, INSERM UMR-S, University of Paris JoVE 66362 Medicine
Author Spotlight: Context Dependent Blood Collection Methods in Rats (Video) | JoVE Laura Charlès1,2,3, Thomas Agius*4,5, Irina Filz von Reiterdank*1,2,3,6, Janna Hagedorn1,2,3, Yanis Berkane1,2,3,7, Hyshem H. Lancia1,2,3, Basak E. Uygun2,3,8, Korkut Uygun2,3,8, Curtis L. Cetrulo Jr.1,2,3,9, Mark A. Randolph1,2,3,9, Alexandre G. Lellouch1,2,3,8 1Vascularized Composite Allotransplantation Laboratory, Massachusetts General Hospital, 2Harvard Medical School, 3Shriners Children’s Boston, 4Center for Engineering in Medicine and Surgery, Massachusetts General Hospital, 5Department of Vascular Surgery, Centre Hospitalier Universitaire Vaudois and University of Lausanne, 6Department of Plastic, Reconstructive and Hand Surgery, University Medical Center Utrecht, 7Department of Plastic, Reconstructive and Aesthetic Surgery, Rennes University Hospital Center (CHU de Rennes), Rennes 1 University, 8Center for Engineering in Medicine and Surgery, Massachusetts General Hospital, 9Plastic Surgery Research Laboratory, Massachusetts General Hospital JoVE 65513 Medicine
The Superficial Inferior Epigastric Artery Axial Flap to Study Ischemic Preconditioning Effects in a Rat Model Yanis Berkane*1,2,3,5, Austin Alana Shamlou*1,2,4,5, Jose Reyes1,2, Hyshem H. Lancia1,2,5, Irina Filz von Reiterdank1,2,5,6,7, Nicolas Bertheuil3, Basak E. Uygun2,5,6, Korkut Uygun1,2,5,6, William G. Austen Jr.2,4, Curtis L. Cetrulo Jr.1,2,4,5, Mark A. Randolph1,2,4,5, Alexandre G. Lellouch1,2,5,6,8 1Vascularized Composite Allotransplantation Laboratory, Massachusetts General Hospital, 2Harvard Medical School, 3Department of Plastic, Reconstructive and Aesthetic Surgery, Rennes University Hospital Center (CHU de Rennes), University of Rennes 1, 4Plastic Surgery Research Laboratory, Massachusetts General Hospital, 5Shriners Children's Boston, 6Center for Engineering in Medicine and Surgery, Massachusetts General Hospital, 7Department of Plastic Surgery and Hand Surgery, University Medical Center Utrecht, 8Department of Plastic, Reconstructive, and Aesthetic Surgery, Groupe Almaviva Santé, Clinique de l'Alma JoVE 64980 Immunology and Infection
A Reliable Porcine Fascio-Cutaneous Flap Model for Vascularized Composite Allografts Bioengineering Studies Victor Pozzo1,2,4, Golda Romano1,2,4, Marion Goutard1,2,4, Elise Lupon1,2,4, Pierre Tawa1,2,4, Aylin Acun3,4,5, Alec R. Andrews2, Corentin B. Taveau1,2,4,6, Basak E. Uygun1,2,3,4, Mark A. Randolph1,2,4, Curtis L. Cetrulo1,2,4, Alexandre G. Lellouch1,2,4,6 1Division of Plastic and Reconstructive Surgery, Massachusetts General Hospital, Harvard Medical School, 2Vascularized Composite Allotransplantation Laboratory, Center for Transplantation Sciences, Massachusetts General Hospital, Harvard Medical School, 3Center for Engineering in Medicine and Surgery, Massachusetts General Hospital, Harvard Medical School, 4Shriners Hospital for Children, 5Department of Biomedical Engineering, Widener University, 6Service de Chirurgie Plastique, Hôpital Européen Georges Pompidou, Assistance Publique-Hôpitaux de Paris (APHP), Université Paris Descartes JoVE 63557 Bioengineering
Functional Human Liver Preservation and Recovery by Means of Subnormothermic Machine Perfusion Bote G. Bruinsma*1, James H. Avruch*2, Pepijn D. Weeder1, Gautham V. Sridharan1, Basak E. Uygun1, Negin G. Karimian1, Robert J. Porte3, James F. Markmann2, Heidi Yeh2, Korkut Uygun1 1Center for Engineering in Medicine, Dept. of Surgery, Massachusetts General Hospital, Harvard Medical School, 2Transplant Center, Dept. of Surgery, Massachusetts General Hospital, Harvard Medical School, 3Section of Hepatobiliary Surgery and Liver Transplantation, Department of Surgery, University Medical Center Groningen, University of Groningen JoVE 52777 Medicine
Decellularization and Recellularization of Whole Livers Basak E. Uygun1, Gavrielle Price1, Nima Saeidi1, Maria-Louisa Izamis1, Tim Berendsen1, Martin Yarmush1, Korkut Uygun1 1Center for Engineering in Medicine, Massachusetts General Hospital, Harvard Medical School, Shriners Hospitals for Children JoVE 2394 Bioengineering
