Birgit Schilling

Publications

• Cytotrophoblast Extracellular Vesicles Enhance Decidual Cell Secretion of Immune Modulators Via TNF-alpha
  Development (Cambridge, England). Aug, 2020  |   Pubmed ID: 32747437
• Translational Control of One-carbon Metabolism Underpins Ribosomal Protein Phenotypes in Cell Division and Longevity
  ELife. May, 2020  |   Pubmed ID: 32432546
• The Power of Proteomics to Monitor Senescence-associated Secretory Phenotypes and Beyond: Toward Clinical Applications
  Expert Review of Proteomics. Apr, 2020  |   Pubmed ID: 32425074
• Abundances of Transcripts, Proteins, and Metabolites in the Cell Cycle of Budding Yeast Reveal Coordinate Control of Lipid Metabolism
  Molecular Biology of the Cell. 05, 2020  |   Pubmed ID: 32129706
• Skyline for Small Molecules: A Unifying Software Package for Quantitative Metabolomics
  Journal of Proteome Research. Apr, 2020  |   Pubmed ID: 31984744
• Activating Transcription Factor 4 (ATF4) Promotes Skeletal Muscle Atrophy by Forming a Heterodimer with the Transcriptional Regulator C/EBPβ
  The Journal of Biological Chemistry. Feb, 2020  |   Pubmed ID: 31953319
• A Proteomic Atlas of Senescence-associated Secretomes for Aging Biomarker Development
  PLoS Biology. Jan, 2020  |   Pubmed ID: 31945054
• Proteome and Secretome Dynamics of Human Retinal Pigment Epithelium in Response to Reactive Oxygen Species
  Scientific Reports. Oct, 2019  |   Pubmed ID: 31659173
• Dietary Sugars Alter Hepatic Fatty Acid Oxidation Via Transcriptional and Post-translational Modifications of Mitochondrial Proteins
  Cell Metabolism. Oct, 2019  |   Pubmed ID: 31577934
• Sirtuin 5 Regulates Proximal Tubule Fatty Acid Oxidation to Protect Against AKI
  Journal of the American Society of Nephrology : JASN. Dec, 2019  |   Pubmed ID: 31575700
• SILAC Analysis Reveals Increased Secretion of Hemostasis-Related Factors by Senescent Cells
  Cell Reports. Sep, 2019  |   Pubmed ID: 31553904
• Accumulation of "Old Proteins" and the Critical Need for MS-based Protein Turnover Measurements in Aging and Longevity
  Proteomics. Aug, 2019  |   Pubmed ID: 31408259
• Post-translational Protein Acetylation: An Elegant Mechanism for Bacteria to Dynamically Regulate Metabolic Functions
  Frontiers in Microbiology. 2019  |   Pubmed ID: 31354686
• High-Resolution Mass Spectrometry to Identify and Quantify Acetylation Protein Targets
  Methods in Molecular Biology (Clifton, N.J.). 2019  |   Pubmed ID: 31087289
• Regulation of UCP1 and Mitochondrial Metabolism in Brown Adipose Tissue by Reversible Succinylation
  Molecular Cell. 05, 2019  |   Pubmed ID: 31000437
• Correction for Christensen Et Al., "Identification of Novel Protein Lysine Acetyltransferases in Escherichia Coli"
  MBio. 04, 2019  |   Pubmed ID: 30967468
• JNK Modifies Neuronal Metabolism to Promote Proteostasis and Longevity
  Aging Cell. 06, 2019  |   Pubmed ID: 30810280
• Global Lysine Acetylation in Results from Growth Conditions That Favor Acetate Fermentation
  Journal of Bacteriology. 05, 2019  |   Pubmed ID: 30782634
• Temporal Dynamics of Liver Mitochondrial Protein Acetylation and Succinylation and Metabolites Due to High Fat Diet And/or Excess Glucose or Fructose
  PloS One. 2018  |   Pubmed ID: 30586434
• Identification of Novel Protein Lysine Acetyltransferases in Escherichia Coli
  MBio. 10, 2018  |   Pubmed ID: 30352934
• Identifying Ubiquitinated Proteins and Aggregates
  Aging. 10, 2018  |   Pubmed ID: 30335616
• Impairment of Angiogenesis by Fatty Acid Synthase Inhibition Involves MTOR Malonylation
  Cell Metabolism. 12, 2018  |   Pubmed ID: 30146486
• Simultaneous Quantification of the Acetylome and Succinylome by 'One-Pot' Affinity Enrichment
  Proteomics. 09, 2018  |   Pubmed ID: 30035354
• Removing 4E-BP Enables Synapses to Refine Without Postsynaptic Activity
  Cell Reports. 04, 2018  |   Pubmed ID: 29617653
• Protein Turnover in Aging and Longevity
  Proteomics. Mar, 2018  |   Pubmed ID: 29453826
• An Acetylatable Lysine Controls CRP Function in E. Coli
  Molecular Microbiology. Jan, 2018  |   Pubmed ID: 29105190
• Ancient Regulatory Role of Lysine Acetylation in Central Metabolism
  MBio. Nov, 2017  |   Pubmed ID: 29184018
• Characterization of Inner and Outer Membrane Proteins FromStrains LVS and Schu S4 and Identification of Potential Subunit Vaccine Candidates
  MBio. Oct, 2017  |   Pubmed ID: 29018123
• Multi-laboratory Assessment of Reproducibility, Qualitative and Quantitative Performance of SWATH-mass Spectrometry
  Nature Communications. 08, 2017  |   Pubmed ID: 28827567
• PIQED: Automated Identification and Quantification of Protein Modifications from DIA-MS Data
  Nature Methods. Jun, 2017  |   Pubmed ID: 28661500
• Identification and Characterization of AckA-dependent Protein Acetylation in Neisseria Gonorrhoeae
  PloS One. 2017  |   Pubmed ID: 28654654
• MSstatsQC: Longitudinal System Suitability Monitoring and Quality Control for Targeted Proteomic Experiments
  Molecular & Cellular Proteomics : MCP. Jul, 2017  |   Pubmed ID: 28483925
• Clinical Applications of Quantitative Proteomics Using Targeted and Untargeted Data-independent Acquisition Techniques
  Expert Review of Proteomics. 05, 2017  |   Pubmed ID: 28436239
• Generation of High-Quality SWATHAcquisition Data for Label-free Quantitative Proteomics Studies Using TripleTOFMass Spectrometers
  Methods in Molecular Biology (Clifton, N.J.). 2017  |   Pubmed ID: 28188533
• Vitamin D Promotes Protein Homeostasis and Longevity Via the Stress Response Pathway Genes Skn-1, Ire-1, and Xbp-1
  Cell Reports. 10, 2016  |   Pubmed ID: 27783938
• Stable Nuclear Expression of ATP8 and ATP6 Genes Rescues a MtDNA Complex V Null Mutant
  Nucleic Acids Research. Nov, 2016  |   Pubmed ID: 27596602
• Quantification of Lysine Acetylation and Succinylation Stoichiometry in Proteins Using Mass Spectrometric Data-Independent Acquisitions (SWATH)
  Journal of the American Society for Mass Spectrometry. Nov, 2016  |   Pubmed ID: 27590315
• Gadd45a Protein Promotes Skeletal Muscle Atrophy by Forming a Complex with the Protein Kinase MEKK4
  The Journal of Biological Chemistry. 08, 2016  |   Pubmed ID: 27358404
• Acetylated Tau Obstructs KIBRA-Mediated Signaling in Synaptic Plasticity and Promotes Tauopathy-Related Memory Loss
  Neuron. 04, 2016  |   Pubmed ID: 27041503
• Multiplexed, Scheduled, High-Resolution Parallel Reaction Monitoring on a Full Scan QqTOF Instrument with Integrated Data-Dependent and Targeted Mass Spectrometric Workflows
  Analytical Chemistry. Oct, 2015  |   Pubmed ID: 26398777
• Critical Role of Acetylation in Tau-mediated Neurodegeneration and Cognitive Deficits
  Nature Medicine. Oct, 2015  |   Pubmed ID: 26390242
• Protein Acetylation Dynamics in Response to Carbon Overflow in Escherichia Coli
  Molecular Microbiology. Dec, 2015  |   Pubmed ID: 26264774
• SIRT1 Deacetylates RORγt and Enhances Th17 Cell Generation
  The Journal of Experimental Medicine. May, 2015  |   Pubmed ID: 25918343
• Large-Scale Interlaboratory Study to Develop, Analytically Validate and Apply Highly Multiplexed, Quantitative Peptide Assays to Measure Cancer-Relevant Proteins in Plasma
  Molecular & Cellular Proteomics : MCP. Sep, 2015  |   Pubmed ID: 25693799
• Iron Promotes Protein Insolubility and Aging in C. Elegans
  Aging. Nov, 2014  |   Pubmed ID: 25554795
• Panorama: a Targeted Proteomics Knowledge Base
  Journal of Proteome Research. Sep, 2014  |   Pubmed ID: 25102069
• RPL24: a Potential Therapeutic Target Whose Depletion or Acetylation Inhibits Polysome Assembly and Cancer Cell Growth
  Oncotarget. Jul, 2014  |   Pubmed ID: 24970821
• Variation and Quantification Among a Target Set of Phosphopeptides in Human Plasma by Multiple Reaction Monitoring and SWATH-MS2 Data-independent Acquisition
  Electrophoresis. Dec, 2014  |   Pubmed ID: 24853916
• Structural, Kinetic and Proteomic Characterization of Acetyl Phosphate-dependent Bacterial Protein Acetylation
  PloS One. 2014  |   Pubmed ID: 24756028
• Phosphoprotein Secretome of Tumor Cells As a Source of Candidates for Breast Cancer Biomarkers in Plasma
  Molecular & Cellular Proteomics : MCP. Apr, 2014  |   Pubmed ID: 24505115
• Site-specific Acylation Changes in the Lipid A of Escherichia Coli LpxL Mutants Grown at High Temperatures
  Innate Immunity. Apr, 2014  |   Pubmed ID: 23812252
• Label-Free Quantitation and Mapping of the ErbB2 Tumor Receptor by Multiple Protease Digestion with Data-Dependent (MS1) and Data-Independent (MS2) Acquisitions
  International Journal of Proteomics. 2013  |   Pubmed ID: 23710360
• Label-free Quantitative Proteomics of the Lysine Acetylome in Mitochondria Identifies Substrates of SIRT3 in Metabolic Pathways
  Proceedings of the National Academy of Sciences of the United States of America. Apr, 2013  |   Pubmed ID: 23576753
• Ligand Binding Promotes CDK-dependent Phosphorylation of ER-alpha on Hinge Serine 294 but Inhibits Ligand-independent Phosphorylation of Serine 305
  Molecular Cancer Research : MCR. Aug, 2012  |   Pubmed ID: 22669764
• Ubiquitin-specific Peptidase 9, X-linked (USP9X) Modulates Activity of Mammalian Target of Rapamycin (mTOR)
  The Journal of Biological Chemistry. Jun, 2012  |   Pubmed ID: 22544753
• Platform-independent and Label-free Quantitation of Proteomic Data Using MS1 Extracted Ion Chromatograms in Skyline: Application to Protein Acetylation and Phosphorylation
  Molecular & Cellular Proteomics : MCP. May, 2012  |   Pubmed ID: 22454539
• A Lectin Chromatography/mass Spectrometry Discovery Workflow Identifies Putative Biomarkers of Aggressive Breast Cancers
  Journal of Proteome Research. Feb, 2012  |   Pubmed ID: 22309216
• Mass Spectrometric Identification of Novel Lysine Acetylation Sites in Huntingtin
  Molecular & Cellular Proteomics : MCP. Oct, 2011  |   Pubmed ID: 21685499
• ScanRanker: Quality Assessment of Tandem Mass Spectra Via Sequence Tagging
  Journal of Proteome Research. Jul, 2011  |   Pubmed ID: 21520941
• Confident Identification of 3-nitrotyrosine Modifications in Mass Spectral Data Across Multiple Mass Spectrometry Platforms
  Journal of Proteomics. Oct, 2011  |   Pubmed ID: 21514405
• A Lectin Affinity Workflow Targeting Glycosite-specific, Cancer-related Carbohydrate Structures in Trypsin-digested Human Plasma
  Analytical Biochemistry. Jan, 2011  |   Pubmed ID: 20705048
• Identification of New Modulators and Protein Alterations in Non-apoptotic Programmed Cell Death
  Journal of Cellular Biochemistry. Dec, 2010  |   Pubmed ID: 20830744
• Targeted Quantitation of Site-specific Cysteine Oxidation in Endogenous Proteins Using a Differential Alkylation and Multiple Reaction Monitoring Mass Spectrometry Approach
  Molecular & Cellular Proteomics : MCP. Jul, 2010  |   Pubmed ID: 20233844
• Repeatability and Reproducibility in Proteomic Identifications by Liquid Chromatography-tandem Mass Spectrometry
  Journal of Proteome Research. Feb, 2010  |   Pubmed ID: 19921851
• Interlaboratory Study Characterizing a Yeast Performance Standard for Benchmarking LC-MS Platform Performance
  Molecular & Cellular Proteomics : MCP. Feb, 2010  |   Pubmed ID: 19858499
• Performance Metrics for Liquid Chromatography-tandem Mass Spectrometry Systems in Proteomics Analyses
  Molecular & Cellular Proteomics : MCP. Feb, 2010  |   Pubmed ID: 19837981
• The Mycobacterium Bovis Bacille Calmette-Guerin Phagosome Proteome
  Molecular & Cellular Proteomics : MCP. Jan, 2010  |   Pubmed ID: 19815536
• Preferentially Increased Nitration of Alpha-synuclein at Tyrosine-39 in a Cellular Oxidative Model of Parkinson's Disease
  Analytical Chemistry. Sep, 2009  |   Pubmed ID: 19697948
• Multi-site Assessment of the Precision and Reproducibility of Multiple Reaction Monitoring-based Measurements of Proteins in Plasma
  Nature Biotechnology. Jul, 2009  |   Pubmed ID: 19561596
• IDPicker 2.0: Improved Protein Assembly with High Discrimination Peptide Identification Filtering
  Journal of Proteome Research. Aug, 2009  |   Pubmed ID: 19522537
• Systematic Mapping of Posttranslational Modifications in Human Estrogen Receptor-alpha with Emphasis on Novel Phosphorylation Sites
  Molecular & Cellular Proteomics : MCP. Mar, 2009  |   Pubmed ID: 18984578
• A Novel Serine Phosphorylation Site Detected in the N-terminal Domain of Estrogen Receptor Isolated from Human Breast Cancer Cells
  Journal of the American Society for Mass Spectrometry. May, 2008  |   Pubmed ID: 18367407
• Partial Acetylation of Lysine Residues Improves Intraprotein Cross-linking
  Analytical Chemistry. Feb, 2008  |   Pubmed ID: 18201069
• Identification of LpxL, a Late Acyltransferase of Francisella Tularensis
  Infection and Immunity. Nov, 2007  |   Pubmed ID: 17724076
• Mitochondrial Oxidative Stress Causes Hyperphosphorylation of Tau
  PloS One. 2007  |   Pubmed ID: 17579710
• Small-scale Immunopurification of Cytochrome C Oxidase for a High-throughput Multiplexing Analysis of Enzyme Activity and Amount
  Biotechnology and Applied Biochemistry. Dec, 2007  |   Pubmed ID: 17508937
• Characterization of Lipid A Acylation Patterns in Francisella Tularensis, Francisella Novicida, and Francisella Philomiragia Using Multiple-stage Mass Spectrometry and Matrix-assisted Laser Desorption/ionization on an Intermediate Vacuum Source Linear Ion Trap
  Analytical Chemistry. Feb, 2007  |   Pubmed ID: 17263332
• Novel Pathways Associated with Quinone-induced Stress in Breast Cancer Cells
  Drug Metabolism Reviews. 2006  |   Pubmed ID: 17145690
• Huntingtin Phosphorylation Sites Mapped by Mass Spectrometry. Modulation of Cleavage and Toxicity
  The Journal of Biological Chemistry. Aug, 2006  |   Pubmed ID: 16782707
• Proteomic Analysis of Succinate Dehydrogenase and Ubiquinol-cytochrome C Reductase (Complex II and III) Isolated by Immunoprecipitation from Bovine and Mouse Heart Mitochondria
  Biochimica Et Biophysica Acta. Feb, 2006  |   Pubmed ID: 16120479
• A Pilot Proteomic Study of Amyloid Precursor Interactors in Alzheimer's Disease
  Annals of Neurology. Aug, 2005  |   Pubmed ID: 16049941
• Mass Spectrometric Identification of a Novel Phosphorylation Site in Subunit NDUFA10 of Bovine Mitochondrial Complex I
  FEBS Letters. Apr, 2005  |   Pubmed ID: 15848193
• Rapid Purification and Mass Spectrometric Characterization of Mitochondrial NADH Dehydrogenase (Complex I) from Rodent Brain and a Dopaminergic Neuronal Cell Line
  Molecular & Cellular Proteomics : MCP. Jan, 2005  |   Pubmed ID: 15591592
• Novel Modification of Lipid A of Francisella Tularensis
  Infection and Immunity. Sep, 2004  |   Pubmed ID: 15322031
• A Novel Lectin, DltA, is Required for Expression of a Full Serum Resistance Phenotype in Haemophilus Ducreyi
  Infection and Immunity. Jun, 2004  |   Pubmed ID: 15155648
• Proteomic and Immunochemical Characterization of a Role for Stathmin in Adult Neurogenesis
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Feb, 2004  |   Pubmed ID: 14769823
• Molecular Components of a Cell Death Pathway Activated by Endoplasmic Reticulum Stress
  The Journal of Biological Chemistry. Jan, 2004  |   Pubmed ID: 14561754
• Isotopically Labeled Crosslinking Reagents: Resolution of Mass Degeneracy in the Identification of Crosslinked Peptides
  Bioorganic & Medicinal Chemistry Letters. Nov, 2003  |   Pubmed ID: 14592499
• Phosphospecific Proteolysis for Mapping Sites of Protein Phosphorylation
  Nature Biotechnology. Sep, 2003  |   Pubmed ID: 12923550
• MS2Assign, Automated Assignment and Nomenclature of Tandem Mass Spectra of Chemically Crosslinked Peptides
  Journal of the American Society for Mass Spectrometry. Aug, 2003  |   Pubmed ID: 12892908
• Cathepsin L in Secretory Vesicles Functions As a Prohormone-processing Enzyme for Production of the Enkephalin Peptide Neurotransmitter
  Proceedings of the National Academy of Sciences of the United States of America. Aug, 2003  |   Pubmed ID: 12869695
• Metabolic Incorporation of Unnatural Sialic Acids into Haemophilus Ducreyi Lipooligosaccharides
  Proceedings of the National Academy of Sciences of the United States of America. Mar, 2003  |   Pubmed ID: 12615992
• Characterization of Lipooligosaccharides from Haemophilus Ducreyi Containing Polylactosamine Repeats
  Journal of the American Society for Mass Spectrometry. Jun, 2002  |   Pubmed ID: 12056572