Blaine A. Pfeifer Chemical and Biological Engineering Department State University of New York at Buffalo Biography Publications Institution JoVE Articles Blaine A. Pfeifer has not added a biography. If you are Blaine A. Pfeifer and would like to personalize this page please email our Author Liaison for assistance. Publications Downstream Reactions and Engineering in the Microbially Reconstituted Pathway for Taxol Applied Microbiology and Biotechnology. May, 2012 | Pubmed ID: 22460591 Toward Biosynthetic Design and Implementation of Escherichia Coli-derived Paclitaxel and Other Heterologous Polyisoprene Compounds Applied and Environmental Microbiology. Apr, 2012 | Pubmed ID: 22287010 Computational Identification of Gene Over-expression Targets for Metabolic Engineering of Taxadiene Production Applied Microbiology and Biotechnology. Mar, 2012 | Pubmed ID: 22124721 Improved E. Coli Erythromycin A Production Through the Application of Metabolic and Bioprocess Engineering Biotechnology Progress. Jan-Feb, 2012 | Pubmed ID: 21905273 Analysis of Heterologous Taxadiene Production in K- and B-derived Escherichia Coli Applied Microbiology and Biotechnology. Feb, 2012 | Pubmed ID: 21850432 Simultaneous Production and Partitioning of Heterologous Polyketide and Isoprenoid Natural Products in an Escherichia Coli Two-phase Bioprocess Journal of Industrial Microbiology & Biotechnology. Nov, 2011 | Pubmed ID: 21487833 Multi-factorial Engineering of Heterologous Polyketide Production in Escherichia Coli Reveals Complex Pathway Interactions Biotechnology and Bioengineering. Jun, 2011 | Pubmed ID: 21337322 Methods and Options for the Heterologous Production of Complex Natural Products Natural Product Reports. Jan, 2011 | Pubmed ID: 21060956 Complete Biosynthesis of Erythromycin A and Designed Analogs Using E. Coli As a Heterologous Host Chemistry & Biology. Nov, 2010 | Pubmed ID: 21095573 Utilizing Elementary Mode Analysis, Pathway Thermodynamics, and a Genetic Algorithm for Metabolic Flux Determination and Optimal Metabolic Network Design BMC Systems Biology. 2010 | Pubmed ID: 20416071 Metabolic Flux Analysis and Pharmaceutical Production Metabolic Engineering. Mar, 2010 | Pubmed ID: 19861167 Computational Analysis of Phenotypic Space in Heterologous Polyketide Biosynthesis--applications to Escherichia Coli, Bacillus Subtilis, and Saccharomyces Cerevisiae Journal of Theoretical Biology. Jan, 2010 | Pubmed ID: 19833139 Investigating the Role of Native Propionyl-CoA and Methylmalonyl-CoA Metabolism on Heterologous Polyketide Production in Escherichia Coli Biotechnology and Bioengineering. Feb, 2010 | Pubmed ID: 19806677 Probing the Heterologous Metabolism Supporting 6-deoxyerythronolide B Biosynthesis in Escherichia Coli Microbial Biotechnology. May, 2009 | Pubmed ID: 21261933 Efficient Experimental Design and Micro-scale Medium Enhancement of 6-deoxyerythronolide B Production Through Escherichia Coli Biotechnology Progress. Sep-Oct, 2009 | Pubmed ID: 19634176 A High-throughput Comparison of Recombinant Gene Expression Parameters for E. Coli-mediated Gene Transfer to P388D1 Macrophage Cells Journal of Biotechnology. Oct, 2008 | Pubmed ID: 18694790 Current Status, Strategies, and Potential for the Metabolic Engineering of Heterologous Polyketides in Escherichia Coli Biotechnology Letters. Aug, 2008 | Pubmed ID: 18488149 A Comparison Between Polymeric Microsphere and Bacterial Vectors for Macrophage P388D1 Gene Delivery Pharmaceutical Research. May, 2008 | Pubmed ID: 18343983 Bacterial Hosts for Natural Product Production Molecular Pharmaceutics. Mar-Apr, 2008 | Pubmed ID: 18232637 Polyketide Analysis Using Mass Spectrometry, Evaporative Light Scattering, and Charged Aerosol Detector Systems Analytical and Bioanalytical Chemistry. Feb, 2008 | Pubmed ID: 18080862 6-deoxyerythronolide B Production Through Chromosomal Localization of the Deoxyerythronolide B Synthase Genes in E. Coli Metabolic Engineering. Jan, 2008 | Pubmed ID: 17959404 Improving Heterologous Polyketide Production in Escherichia Coli by Overexpression of an S-adenosylmethionine Synthetase Gene Applied Microbiology and Biotechnology. Nov, 2007 | Pubmed ID: 17876579 Poly(ester-anhydride):poly(beta-amino Ester) Micro- and Nanospheres: DNA Encapsulation and Cellular Transfection International Journal of Pharmaceutics. Nov, 2005 | Pubmed ID: 16174553 Formulation and Surface Modification of Poly(ester-anhydride) Micro- and Nanospheres Biomaterials. Jan, 2005 | Pubmed ID: 15207458 Biosynthesis of Yersiniabactin, a Complex Polyketide-nonribosomal Peptide, Using Escherichia Coli As a Heterologous Host Applied and Environmental Microbiology. Nov, 2003 | Pubmed ID: 14602630 Precursor-Directed Polyketide Biosynthesis in Escherichia Coli Bioorganic & Medicinal Chemistry Letters. Nov, 2003 | Pubmed ID: 14552761 A Specific Role of the Saccharopolyspora Erythraea Thioesterase II Gene in the Function of Modular Polyketide Synthases Microbiology (Reading, England). Aug, 2003 | Pubmed ID: 12904561 Metabolic Engineering of a Methylmalonyl-CoA Mutase-epimerase Pathway for Complex Polyketide Biosynthesis in Escherichia Coli Biochemistry. Apr, 2002 | Pubmed ID: 11955068 היגיון, שלבים ניסיוניים, והפוטנציאל של יוסינתזה מוצרים הטבעי Heterologous מציע אריתרומיצין האנטיביוטי הקומפלקס הופק באמצעות Ming Jiang1, Haoran Zhang2, Blaine A. Pfeifer1 1Chemical and Biological Engineering Department, State University of New York at Buffalo, 2Chemical Engineering Department, Massachusetts Institute of Technology JoVE 4346 Biology
היגיון, שלבים ניסיוניים, והפוטנציאל של יוסינתזה מוצרים הטבעי Heterologous מציע אריתרומיצין האנטיביוטי הקומפלקס הופק באמצעות Ming Jiang1, Haoran Zhang2, Blaine A. Pfeifer1 1Chemical and Biological Engineering Department, State University of New York at Buffalo, 2Chemical Engineering Department, Massachusetts Institute of Technology JoVE 4346 Biology