Boris Lenhard Institute of Clinical Sciences, Faculty of Medicine Imperial College London Biography Publications Institution JoVE Articles Boris Lenhard has not added a biography. If you are Boris Lenhard and would like to personalize this page please email our Author Liaison for assistance. Publications Computation Resources for Molecular Biology: Special Issue 2019 Journal of Molecular Biology. Jun, 2019 | Pubmed ID: 31152744 Feedforward Regulation of Myc Coordinates Lineage-specific with Housekeeping Gene Expression During B Cell Progenitor Cell Differentiation PLoS Biology. Apr, 2019 | Pubmed ID: 30978178 DNA Stretching Induces Cas9 Off-target Activity Nature Structural & Molecular Biology. Mar, 2019 | Pubmed ID: 30804513 Saccharomyces Cerevisiae Displays a Stable Transcription Start Site Landscape in Multiple Conditions FEMS Yeast Research. 03, 2019 | Pubmed ID: 30590648 A Novel Measure of Non-coding Genome Conservation Identifies Genomic Regulatory Blocks Within Primates Bioinformatics (Oxford, England). Dec, 2018 | Pubmed ID: 30535005 Amphioxus Functional Genomics and the Origins of Vertebrate Gene Regulation Nature. 12, 2018 | Pubmed ID: 30464347 SLIC-CAGE: High-resolution Transcription Start Site Mapping Using Nanogram-levels of Total RNA Genome Research. 12, 2018 | Pubmed ID: 30404778 Control of Inducible Gene Expression Links Cohesin to Hematopoietic Progenitor Self-renewal and Differentiation Nature Immunology. 09, 2018 | Pubmed ID: 30127433 BCL11B Mutations in Patients Affected by a Neurodevelopmental Disorder with Reduced Type 2 Innate Lymphoid Cells Brain : a Journal of Neurology. Aug, 2018 | Pubmed ID: 29985992 Integrated Analysis Sheds Light on Evolutionary Trajectories of Young Transcription Start Sites in the Human Genome Genome Research. 05, 2018 | Pubmed ID: 29618487 Epigenetic Reprogramming Enables the Transition from Primordial Germ Cell to Gonocyte Nature. 03, 2018 | Pubmed ID: 29513657 Distinct Core Promoter Codes Drive Transcription Initiation at Key Developmental Transitions in a Marine Chordate BMC Genomics. 02, 2018 | Pubmed ID: 29482522 JASPAR 2018: Update of the Open-access Database of Transcription Factor Binding Profiles and Its Web Framework Nucleic Acids Research. 01, 2018 | Pubmed ID: 29161433 JASPAR 2018: Update of the Open-access Database of Transcription Factor Binding Profiles and Its Web Framework Nucleic Acids Research. Jan, 2018 | Pubmed ID: 29140473 Conserved Non-coding Elements: Developmental Gene Regulation Meets Genome Organization Nucleic Acids Research. Dec, 2017 | Pubmed ID: 29121339 Transcriptional Memory of Cells of Origin Overrides β-catenin Requirement of MLL Cancer Stem Cells The EMBO Journal. 11, 2017 | Pubmed ID: 28978671 Topologically Associating Domains Are Ancient Features That Coincide with Metazoan Clusters of Extreme Noncoding Conservation Nature Communications. 09, 2017 | Pubmed ID: 28874668 Core Promoters Across the Genome Nature Biotechnology. 02, 2017 | Pubmed ID: 28178253 Allele-specific Analysis of Cell Fusion-mediated Pluripotent Reprograming Reveals Distinct and Predictive Susceptibilities of Human X-linked Genes to Reactivation Genome Biology. 01, 2017 | Pubmed ID: 28118853 Naturally Occurring Isoleucyl-tRNA Synthetase Without TRNA-dependent Pre-transfer Editing The Journal of Biological Chemistry. Apr, 2016 | Pubmed ID: 26921320 TFBSTools: an R/bioconductor Package for Transcription Factor Binding Site Analysis Bioinformatics (Oxford, England). 05, 2016 | Pubmed ID: 26794315 Promoter Architectures and Developmental Gene Regulation Seminars in Cell & Developmental Biology. 09, 2016 | Pubmed ID: 26783721 Targeting Aberrant Epigenetic Networks Mediated by PRMT1 and KDM4C in Acute Myeloid Leukemia Cancer Cell. Jan, 2016 | Pubmed ID: 26766589 Transcriptional, Post-transcriptional and Chromatin-associated Regulation of Pri-miRNAs, Pre-miRNAs and MoRNAs Nucleic Acids Research. Apr, 2016 | Pubmed ID: 26673698 JASPAR 2016: a Major Expansion and Update of the Open-access Database of Transcription Factor Binding Profiles Nucleic Acids Research. Jan, 2016 | Pubmed ID: 26531826 Control of Developmentally Primed Erythroid Genes by Combinatorial Co-repressor Actions Nature Communications. Nov, 2015 | Pubmed ID: 26593974 GenomicInteractions: An R/Bioconductor Package for Manipulating and Investigating Chromatin Interaction Data BMC Genomics. Nov, 2015 | Pubmed ID: 26576536 Copy Number Variants in Patients with Intellectual Disability Affect the Regulation of ARX Transcription Factor Gene Human Genetics. Nov, 2015 | Pubmed ID: 26337422 Long-range Evolutionary Constraints Reveal Cis-regulatory Interactions on the Human X Chromosome Nature Communications. Apr, 2015 | Pubmed ID: 25908307 Spatial Enhancer Clustering and Regulation of Enhancer-proximal Genes by Cohesin Genome Research. Apr, 2015 | Pubmed ID: 25677180 CAGEr: Precise TSS Data Retrieval and High-resolution Promoterome Mining for Integrative Analyses Nucleic Acids Research. Apr, 2015 | Pubmed ID: 25653163 Trans-splicing and Operons in Metazoans: Translational Control in Maternally Regulated Development and Recovery from Growth Arrest Molecular Biology and Evolution. Mar, 2015 | Pubmed ID: 25525214 HBS1L-MYB Intergenic Variants Modulate Fetal Hemoglobin Via Long-range MYB Enhancers The Journal of Clinical Investigation. Apr, 2014 | Pubmed ID: 24614105 Computational Characterization of Modes of Transcriptional Regulation of Nuclear Receptor Genes PloS One. 2014 | Pubmed ID: 24551185 Two Independent Transcription Initiation Codes Overlap on Vertebrate Core Promoters Nature. Mar, 2014 | Pubmed ID: 24531765 JASPAR 2014: an Extensively Expanded and Updated Open-access Database of Transcription Factor Binding Profiles Nucleic Acids Research. Jan, 2014 | Pubmed ID: 24194598 The Mystery of Extreme Non-coding Conservation Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. Dec, 2013 | Pubmed ID: 24218634 Cohesin-based Chromatin Interactions Enable Regulated Gene Expression Within Preexisting Architectural Compartments Genome Research. Dec, 2013 | Pubmed ID: 24002784 R3Cseq: an R/Bioconductor Package for the Discovery of Long-range Genomic Interactions from Chromosome Conformation Capture and Next-generation Sequencing Data Nucleic Acids Research. Jul, 2013 | Pubmed ID: 23671339 Patterns of Regulatory Activity Across Diverse Human Cell Types Predict Tissue Identity, Transcription Factor Binding, and Long-range Interactions Genome Research. May, 2013 | Pubmed ID: 23482648 OikoBase: a Genomics and Developmental Transcriptomics Resource for the Urochordate Oikopleura Dioica Nucleic Acids Research. Jan, 2013 | Pubmed ID: 23185044 A Novel Complex, RUNX1-MYEF2, Represses Hematopoietic Genes in Erythroid Cells Molecular and Cellular Biology. Oct, 2012 | Pubmed ID: 22801375 Conservation and Divergence in Toll-like Receptor 4-regulated Gene Expression in Primary Human Versus Mouse Macrophages Proceedings of the National Academy of Sciences of the United States of America. Apr, 2012 | Pubmed ID: 22451944 Metazoan Promoters: Emerging Characteristics and Insights into Transcriptional Regulation Nature Reviews. Genetics. Mar, 2012 | Pubmed ID: 22392219 Making Enhancers from Spare Parts of the Genome Genome Biology. Dec, 2011 | Pubmed ID: 22206586 Transcriptie start site mapping met behulp van Super-lage input Carrier-CAGE Nevena Cvetesic1,2, Elena Pahita1,2, Boris Lenhard1,2,3 1Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, 2MRC London Institute of Medical Sciences, 3Sars International Centre for Marine Molecular Biology, University of Bergen JoVE 59805 Genetics
Transcriptie start site mapping met behulp van Super-lage input Carrier-CAGE Nevena Cvetesic1,2, Elena Pahita1,2, Boris Lenhard1,2,3 1Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, 2MRC London Institute of Medical Sciences, 3Sars International Centre for Marine Molecular Biology, University of Bergen JoVE 59805 Genetics
