Brett Nixon

Publications

• Proteomic Profiling of Crocodile Spermatozoa Refutes the Tenet That Post-testicular Maturation is Restricted to Mammals
  Molecular & Cellular Proteomics : MCP. Aug, 2018  |   Pubmed ID: 30072580
• Double Strand Break DNA Repair Occurs Via Non-Homologous End-Joining in Mouse MII Oocytes
  Scientific Reports. Jun, 2018  |   Pubmed ID: 29946146
• Mouse Quiescin Sulfhydryl Oxidases Exhibit Distinct Epididymal Luminal Distribution with Segment-Specific Sperm Surface Associations
  Biology of Reproduction. May, 2018  |   Pubmed ID: 29800099
• Improved Methods of DNA Extraction from Human Spermatozoa That Mitigate Experimentally-induced Oxidative DNA Damage
  PloS One. 2018  |   Pubmed ID: 29579126
• Pharmacological Inhibition of Arachidonate 15-lipoxygenase Protects Human Spermatozoa Against Oxidative Stress
  Biology of Reproduction. Jun, 2018  |   Pubmed ID: 29546268
• Characteristics of the Epididymal Luminal Environment Responsible for Sperm Maturation and Storage
  Frontiers in Endocrinology. 2018  |   Pubmed ID: 29541061
• Heat Exposure Induces Oxidative Stress and DNA Damage in the Male Germ Line
  Biology of Reproduction. Apr, 2018  |   Pubmed ID: 29351587
• Molecular Mechanisms Responsible for Increased Vulnerability of the Ageing Oocyte to Oxidative Damage
  Oxidative Medicine and Cellular Longevity. 2017  |   Pubmed ID: 29312475
• Characterization of a Novel Role for the Dynamin Mechanoenzymes in the Regulation of Human Sperm Acrosomal Exocytosis
  Molecular Human Reproduction. Oct, 2017  |   Pubmed ID: 29044420
• Analysis of the Small Non-protein-coding RNA Profile of Mouse Spermatozoa Reveals Specific Enrichment of PiRNAs Within Mature Spermatozoa
  RNA Biology. 12, 2017  |   Pubmed ID: 28816603
• The Lipid Peroxidation Product 4-hydroxynonenal Contributes to Oxidative Stress-mediated Deterioration of the Ageing Oocyte
  Scientific Reports. Jul, 2017  |   Pubmed ID: 28740075
• Electrophilic Aldehyde Products of Lipid Peroxidation Selectively Adduct to Heat Shock Protein 90 and Arylsulfatase A in Stallion Spermatozoa
  Biology of Reproduction. 01, 2017  |   Pubmed ID: 28395341
• Developmental Expression of the Dynamin Family of Mechanoenzymes in the Mouse Epididymis
  Biology of Reproduction. 01, 2017  |   Pubmed ID: 28395327
• Heat Shock Protein A2 (HSPA2): Regulatory Roles in Germ Cell Development and Sperm Function
  Advances in Anatomy, Embryology, and Cell Biology. 2017  |   Pubmed ID: 28389751
• Epididymal CYP2E1 Plays a Critical Role in Acrylamide-induced DNA Damage in Spermatozoa and Paternally Mediated Embryonic Resorptions†
  Biology of Reproduction. Apr, 2017  |   Pubmed ID: 28379345
• Inhibition of Arachidonate 15-lipoxygenase Prevents 4-hydroxynonenal-induced Protein Damage in Male Germ Cells
  Biology of Reproduction. 03, 2017  |   Pubmed ID: 28339608
• Proteolytic Degradation of Heat Shock Protein A2 Occurs in Response to Oxidative Stress in Male Germ Cells of the Mouse
  Molecular Human Reproduction. 02, 2017  |   Pubmed ID: 27932549
• Non-surgical Sterilisation Methods May Offer a Sustainable Solution to Feral Horse (Equus Caballus) Overpopulation
  Reproduction, Fertility, and Development. Sep, 2017  |   Pubmed ID: 27700983
• Biochemical Alterations in the Oocyte in Support of Early Embryonic Development
  Cellular and Molecular Life Sciences : CMLS. 02, 2017  |   Pubmed ID: 27604868
• Dynamin 2 is Essential for Mammalian Spermatogenesis
  Scientific Reports. 10, 2016  |   Pubmed ID: 27725702
• Formation and Dissociation of Sperm Bundles in Monotremes
  Biology of Reproduction. 10, 2016  |   Pubmed ID: 27557648
• Characterisation of Mouse Epididymosomes Reveals a Complex Profile of MicroRNAs and a Potential Mechanism for Modification of the Sperm Epigenome
  Scientific Reports. 08, 2016  |   Pubmed ID: 27549865
• Data on the Concentrations of Etoposide, PSC833, BAPTA-AM, and Cycloheximide That Do Not Compromise the Vitality of Mature Mouse Oocytes, Parthenogencially Activated and Fertilized Embryos
  Data in Brief. Sep, 2016  |   Pubmed ID: 27547800
• Identification of a Key Role for Permeability Glycoprotein in Enhancing the Cellular Defense Mechanisms of Fertilized Oocytes
  Developmental Biology. 09, 2016  |   Pubmed ID: 27397031
• Chronic Acrylamide Exposure in Male Mice Induces DNA Damage to Spermatozoa; Potential for Amelioration by Resveratrol
  Reproductive Toxicology (Elmsford, N.Y.). 08, 2016  |   Pubmed ID: 27174446
• The Australian Saltwater Crocodile (Crocodylus Porosus) Provides Evidence That the Capacitation of Spermatozoa May Extend Beyond the Mammalian Lineage
  Proceedings. Biological Sciences. 05, 2016  |   Pubmed ID: 27147099
• A Novel Germ Cell Protein, SPIF (sperm PKA Interacting Factor), is Essential for the Formation of a PKA/TCP11 Complex That Undergoes Conformational and Phosphorylation Changes Upon Capacitation
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. 08, 2016  |   Pubmed ID: 27105888
• Heat Shock Protein Member A2 Forms a Stable Complex with Angiotensin Converting Enzyme and Protein Disulfide Isomerase A6 in Human Spermatozoa
  Molecular Human Reproduction. Feb, 2016  |   Pubmed ID: 26676989
• Assessment of MicroRNA Expression in Mouse Epididymal Epithelial Cells and Spermatozoa by Next Generation Sequencing
  Genomics Data. Dec, 2015  |   Pubmed ID: 26697376
• The Impact of Oxidative Stress on Chaperone-mediated Human Sperm-egg Interaction
  Human Reproduction (Oxford, England). Nov, 2015  |   Pubmed ID: 26345691
• The MicroRNA Signature of Mouse Spermatozoa is Substantially Modified During Epididymal Maturation
  Biology of Reproduction. Oct, 2015  |   Pubmed ID: 26333995
• Next Generation Sequencing Analysis Reveals Segmental Patterns of MicroRNA Expression in Mouse Epididymal Epithelial Cells
  PloS One. 2015  |   Pubmed ID: 26270822
• Novel Characterization of the HSPA2-stabilizing Protein BAG6 in Human Spermatozoa
  Molecular Human Reproduction. Oct, 2015  |   Pubmed ID: 26153132
• Are Sperm Capacitation and Apoptosis the Opposite Ends of a Continuum Driven by Oxidative Stress?
  Asian Journal of Andrology. Jul-Aug, 2015  |   Pubmed ID: 25999358
• The 12 (th) International Symposium on Spermatology
  Asian Journal of Andrology. Jul-Aug, 2015  |   Pubmed ID: 25994646
• The Role of the Molecular Chaperone Heat Shock Protein A2 (HSPA2) in Regulating Human Sperm-egg Recognition
  Asian Journal of Andrology. Jul-Aug, 2015  |   Pubmed ID: 25865850
• Glycogen Synthase Kinase 3 Regulates Acrosomal Exocytosis in Mouse Spermatozoa Via Dynamin Phosphorylation
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Jul, 2015  |   Pubmed ID: 25808536
• Mouse Spermatocytes Express CYP2E1 and Respond to Acrylamide Exposure
  PloS One. 2014  |   Pubmed ID: 24788432
• Post-testicular Sperm Maturation and Identification of an Epididymal Protein in the Japanese Quail (Coturnix Coturnix Japonica)
  Reproduction (Cambridge, England). Mar, 2014  |   Pubmed ID: 24298048
• Capacitation in the Presence of Methyl-β-cyclodextrin Results in Enhanced Zona Pellucida-binding Ability of Stallion Spermatozoa
  Reproduction (Cambridge, England). Feb, 2014  |   Pubmed ID: 24194571
• The Rise of Testicular Germ Cell Tumours: the Search for Causes, Risk Factors and Novel Therapeutic Targets
  F1000Research. 2013  |   Pubmed ID: 24555040
• Sperm Capacitation: a Distant Landscape Glimpsed but Unexplored
  Molecular Human Reproduction. Dec, 2013  |   Pubmed ID: 24071444
• Melatonin Prevents Postovulatory Oocyte Aging in the Mouse and Extends the Window for Optimal Fertilization in Vitro
  Biology of Reproduction. Mar, 2013  |   Pubmed ID: 23365415
• Investigation of the Mechanisms by Which the Molecular Chaperone HSPA2 Regulates the Expression of Sperm Surface Receptors Involved in Human Sperm-oocyte Recognition
  Molecular Human Reproduction. Mar, 2013  |   Pubmed ID: 23247813
• The Function of Chaperone Proteins in the Assemblage of Protein Complexes Involved in Gamete Adhesion and Fusion Processes
  Reproduction (Cambridge, England). Feb, 2013  |   Pubmed ID: 23166368
• The Molecular Chaperone HSPA2 Plays a Key Role in Regulating the Expression of Sperm Surface Receptors That Mediate Sperm-egg Recognition
  PloS One. 2012  |   Pubmed ID: 23209833
• Dynamin Regulates Specific Membrane Fusion Events Necessary for Acrosomal Exocytosis in Mouse Spermatozoa
  The Journal of Biological Chemistry. Nov, 2012  |   Pubmed ID: 22977254
• Proteomic Insights into the Maturation and Capacitation of Mammalian Spermatozoa
  Systems Biology in Reproductive Medicine. Aug, 2012  |   Pubmed ID: 22788533
• Chronic Exposure to Acrylamide Induces DNA Damage in Male Germ Cells of Mice
  Toxicological Sciences : an Official Journal of the Society of Toxicology. Sep, 2012  |   Pubmed ID: 22610608
• A Unique Combination of Male Germ Cell MiRNAs Coordinates Gonocyte Differentiation
  PloS One. 2012  |   Pubmed ID: 22536405
• The Role of Molecular Chaperones in Spermatogenesis and the Post-testicular Maturation of Mammalian Spermatozoa
  Human Reproduction Update. Jul, 2012  |   Pubmed ID: 22523110
• Staying Alive: PI3K Pathway Promotes Primordial Follicle Activation and Survival in Response to 3MC-induced Ovotoxicity
  Toxicological Sciences : an Official Journal of the Society of Toxicology. Jul, 2012  |   Pubmed ID: 22505044
• The Chaperonin Containing TCP1 Complex (CCT/TRiC) is Involved in Mediating Sperm-oocyte Interaction
  The Journal of Biological Chemistry. Oct, 2011  |   Pubmed ID: 21880732
• Proteomic and Functional Analysis of Human Sperm Detergent Resistant Membranes
  Journal of Cellular Physiology. Oct, 2011  |   Pubmed ID: 21792924
• Involvement of Multimeric Protein Complexes in Mediating the Capacitation-dependent Binding of Human Spermatozoa to Homologous Zonae Pellucidae
  Developmental Biology. Aug, 2011  |   Pubmed ID: 21672535
• Monotremes Provide a Key to Understanding the Evolutionary Significance of Epididymal Sperm Maturation
  Journal of Andrology. Nov-Dec, 2011  |   Pubmed ID: 21441429
• Cellular Mechanisms Regulating Sperm-zona Pellucida Interaction
  Asian Journal of Andrology. Jan, 2011  |   Pubmed ID: 21042304
• Sperm-zona Pellucida Interaction: Molecular Mechanisms and the Potential for Contraceptive Intervention
  Handbook of Experimental Pharmacology. 2010  |   Pubmed ID: 20839091
• New Insights into Sperm Physiology and Pathology
  Handbook of Experimental Pharmacology. 2010  |   Pubmed ID: 20839089
• Elucidation of the Signaling Pathways That Underpin Capacitation-associated Surface Phosphotyrosine Expression in Mouse Spermatozoa
  Journal of Cellular Physiology. Jul, 2010  |   Pubmed ID: 20232304
• The Biological Significance of Detergent-resistant Membranes in Spermatozoa
  Journal of Reproductive Immunology. Dec, 2009  |   Pubmed ID: 19857901
• DNA Damage in Human Spermatozoa is Highly Correlated with the Efficiency of Chromatin Remodeling and the Formation of 8-hydroxy-2'-deoxyguanosine, a Marker of Oxidative Stress
  Biology of Reproduction. Sep, 2009  |   Pubmed ID: 19494251
• Composition and Significance of Detergent Resistant Membranes in Mouse Spermatozoa
  Journal of Cellular Physiology. Jan, 2009  |   Pubmed ID: 18726997
• Genome Analysis of the Platypus Reveals Unique Signatures of Evolution
  Nature. May, 2008  |   Pubmed ID: 18464734
• Identification of the Molecular Chaperone, Heat Shock Protein 1 (chaperonin 10), in the Reproductive Tract and in Capacitating Spermatozoa in the Male Mouse
  Biology of Reproduction. Jun, 2008  |   Pubmed ID: 18276932
• Investigation of the Role of SRC in Capacitation-associated Tyrosine Phosphorylation of Human Spermatozoa
  Molecular Human Reproduction. Apr, 2008  |   Pubmed ID: 18245108
• Molecular and Functional Characterization of the Rabbit Epididymal Secretory Protein 52, REP52
  Biology of Reproduction. May, 2008  |   Pubmed ID: 18199886
• Proteomic Changes in Mammalian Spermatozoa During Epididymal Maturation
  Asian Journal of Andrology. Jul, 2007  |   Pubmed ID: 17589795
• Role of the Epididymis in Sperm Competition
  Asian Journal of Andrology. Jul, 2007  |   Pubmed ID: 17589786
• The Identification of Mouse Sperm-surface-associated Proteins and Characterization of Their Ability to Act As Decapacitation Factors
  Biology of Reproduction. Feb, 2006  |   Pubmed ID: 16221991
• Evidence for the Involvement of PECAM-1 in a Receptor Mediated Signal-transduction Pathway Regulating Capacitation-associated Tyrosine Phosphorylation in Human Spermatozoa
  Journal of Cell Science. Oct, 2005  |   Pubmed ID: 16219692
• The Role of Molecular Chaperones in Mouse Sperm-egg Interactions
  Molecular and Cellular Endocrinology. Aug, 2005  |   Pubmed ID: 16043280
• Localization and Significance of Molecular Chaperones, Heat Shock Protein 1, and Tumor Rejection Antigen Gp96 in the Male Reproductive Tract and During Capacitation and Acrosome Reaction
  Biology of Reproduction. Feb, 2005  |   Pubmed ID: 15456702
• Tyrosine Phosphorylation Activates Surface Chaperones Facilitating Sperm-zona Recognition
  Journal of Cell Science. Jul, 2004  |   Pubmed ID: 15252132
• Identification of RARhoGAP, a Novel Putative RhoGAP Gene Expressed in Male Germ Cells
  Genomics. Aug, 2004  |   Pubmed ID: 15234003
• Rabbit Epididymal Secretory Proteins. I. Characterization and Hormonal Regulation
  Biology of Reproduction. Jul, 2002  |   Pubmed ID: 12080009