Brian K. Kennedy Department of Biochemistry University of Washington Biography Publications Institution JoVE Articles Brian K. Kennedy has not added a biography. If you are Brian K. Kennedy and would like to personalize this page please email our Author Liaison for assistance. Publications A New Chronological Survival Assay in Mammalian Cell Culture Cell Cycle (Georgetown, Tex.). Jan, 2012 | Pubmed ID: 22214665 Genome-wide Analysis of Yeast Aging Sub-cellular Biochemistry. 2012 | Pubmed ID: 22094426 The Buck Institute: An Inside Look Cell Cycle (Georgetown, Tex.). Dec, 2011 | Pubmed ID: 22157188 Elevated Proteasome Capacity Extends Replicative Lifespan in Saccharomyces Cerevisiae PLoS Genetics. Sep, 2011 | Pubmed ID: 21931558 Sir2 Deletion Prevents Lifespan Extension in 32 Long-lived Mutants Aging Cell. Dec, 2011 | Pubmed ID: 21902802 Aged Worms Erase Epigenetic History Cell Metabolism. Aug, 2011 | Pubmed ID: 21803283 Trinations Aging Symposium Mechanisms of Ageing and Development. Jun-Jul, 2011 | Pubmed ID: 21771608 Decreased Proliferation Kinetics of Mouse Myoblasts Overexpressing FRG1 PloS One. 2011 | Pubmed ID: 21603621 A Genomic Analysis of Chronological Longevity Factors in Budding Yeast Cell Cycle (Georgetown, Tex.). May, 2011 | Pubmed ID: 21447998 Asymmetric Segregation: the Shape of Things to Come? Current Biology : CB. Feb, 2011 | Pubmed ID: 21334292 Quantitative Evidence for Early Life Fitness Defects from 32 Longevity-associated Alleles in Yeast Cell Cycle (Georgetown, Tex.). Jan, 2011 | Pubmed ID: 21191185 Hot Topics in Aging Research: Protein Translation and TOR Signaling, 2010 Aging Cell. Apr, 2011 | Pubmed ID: 21176090 TOR and Ageing: a Complex Pathway for a Complex Process Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. Jan, 2011 | Pubmed ID: 21115526 TOR on the Brain Experimental Gerontology. Feb-Mar, 2011 | Pubmed ID: 20849946 Old Yeast Can't Handle the Noise Molecular Cell. Sep, 2010 | Pubmed ID: 20832716 Downregulation of Lamin A by Tumor Suppressor AIMP3/p18 Leads to a Progeroid Phenotype in Mice Aging Cell. Oct, 2010 | Pubmed ID: 20726853 Progeria Syndromes and Ageing: What is the Connection? Nature Reviews. Molecular Cell Biology. Aug, 2010 | Pubmed ID: 20651707 Cell-extrinsic Defective Lymphocyte Development in Lmna(-/-) Mice PloS One. 2010 | Pubmed ID: 20405040 Translate This ... During Dietary Restriction Cell Metabolism. Oct, 2009 | Pubmed ID: 19808017 Attenuation of Age-related Metabolic Dysfunction in Mice with a Targeted Disruption of the Cbeta Subunit of Protein Kinase A The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences. Dec, 2009 | Pubmed ID: 19776218 Structural Changes to Monomeric CuZn Superoxide Dismutase Caused by the Familial Amyotrophic Lateral Sclerosis-associated Mutation A4V Biophysical Journal. Sep, 2009 | Pubmed ID: 19751676 Hot Topics in Aging Research: Protein Translation, 2009 Aging Cell. Dec, 2009 | Pubmed ID: 19747234 Ageing: A Midlife Longevity Drug? Nature. Jul, 2009 | Pubmed ID: 19606132 The TOR Pathway Comes of Age Biochimica Et Biophysica Acta. Oct, 2009 | Pubmed ID: 19539012 Histone H4 Lysine 16 Acetylation Regulates Cellular Lifespan Nature. Jun, 2009 | Pubmed ID: 19516333 A Molecular Mechanism of Chronological Aging in Yeast Cell Cycle (Georgetown, Tex.). Apr, 2009 | Pubmed ID: 19305133 A-type Nuclear Lamins Act As Transcriptional Repressors when Targeted to Promoters Experimental Cell Research. Apr, 2009 | Pubmed ID: 19272320 Shortest-path Network Analysis is a Useful Approach Toward Identifying Genetic Determinants of Longevity PloS One. 2008 | Pubmed ID: 19030232 Suppression of Proliferative Defects Associated with Processing-defective Lamin A Mutants by HTERT or Inactivation of P53 Molecular Biology of the Cell. Dec, 2008 | Pubmed ID: 18843043 Protein Translation, 2008 Aging Cell. Dec, 2008 | Pubmed ID: 18782345 Age- and Calorie-independent Life Span Extension from Dietary Restriction by Bacterial Deprivation in Caenorhabditis Elegans BMC Developmental Biology. 2008 | Pubmed ID: 18457595 Yeast Life Span Extension by Depletion of 60s Ribosomal Subunits is Mediated by Gcn4 Cell. Apr, 2008 | Pubmed ID: 18423200 Quantitative Evidence for Conserved Longevity Pathways Between Divergent Eukaryotic Species Genome Research. Apr, 2008 | Pubmed ID: 18340043 Dietary Restriction Suppresses Proteotoxicity and Enhances Longevity by an Hsf-1-dependent Mechanism in Caenorhabditis Elegans Aging Cell. Jun, 2008 | Pubmed ID: 18331616 A Method for High-throughput Quantitative Analysis of Yeast Chronological Life Span The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences. Feb, 2008 | Pubmed ID: 18314444 Single-gene Deletions That Restore Mating Competence to Diploid Yeast FEMS Yeast Research. Mar, 2008 | Pubmed ID: 17995956 Protein Translation, 2007 Aging Cell. Dec, 2007 | Pubmed ID: 17941970 Evidence That Proteasome-dependent Degradation of the Retinoblastoma Protein in Cells Lacking A-type Lamins Occurs Independently of Gankyrin and MDM2 PloS One. 2007 | Pubmed ID: 17896003 Does Resveratrol Activate Yeast Sir2 in Vivo? Aging Cell. Aug, 2007 | Pubmed ID: 17635418 Recent Developments in Yeast Aging PLoS Genetics. May, 2007 | Pubmed ID: 17530929 Werner and Hutchinson-Gilford Progeria Syndromes: Mechanistic Basis of Human Progeroid Diseases Nature Reviews. Molecular Cell Biology. May, 2007 | Pubmed ID: 17450177 The Sensitivity of Yeast Mutants to Oleic Acid Implicates the Peroxisome and Other Processes in Membrane Function Genetics. Jan, 2007 | Pubmed ID: 17151231 Genome-wide Identification of Conserved Longevity Genes in Yeast and Worms Mechanisms of Ageing and Development. Jan, 2007 | Pubmed ID: 17126379 Sirtuin-independent Effects of Nicotinamide on Lifespan Extension from Calorie Restriction in Yeast Aging Cell. Dec, 2006 | Pubmed ID: 17129213 Lifespan Extension in Caenorhabditis Elegans by Complete Removal of Food Aging Cell. Dec, 2006 | Pubmed ID: 17081160 Aging: Progeria and the Lamin Connection Current Biology : CB. Aug, 2006 | Pubmed ID: 16920618 Sirtuins in Aging and Age-related Disease Cell. Jul, 2006 | Pubmed ID: 16873059 Stabilization of the Retinoblastoma Protein by A-type Nuclear Lamins is Required for INK4A-mediated Cell Cycle Arrest Molecular and Cellular Biology. Jul, 2006 | Pubmed ID: 16809772 Comment on "HST2 Mediates SIR2-independent Life-span Extension by Calorie Restriction" Science (New York, N.Y.). Jun, 2006 | Pubmed ID: 16741098 Lamin A/C and Emerin Are Critical for Skeletal Muscle Satellite Cell Differentiation Genes & Development. Feb, 2006 | Pubmed ID: 16481476 Extension of Chronological Life Span in Yeast by Decreased TOR Pathway Signaling Genes & Development. Jan, 2006 | Pubmed ID: 16418483 Increased Life Span Due to Calorie Restriction in Respiratory-deficient Yeast PLoS Genetics. Nov, 2005 | Pubmed ID: 16311627 Regulation of Yeast Replicative Life Span by TOR and Sch9 in Response to Nutrients Science (New York, N.Y.). Nov, 2005 | Pubmed ID: 16293764 The Enigmatic Role of Sir2 in Aging Cell. Nov, 2005 | Pubmed ID: 16286003 HIV Protease Inhibitors Block Adipocyte Differentiation Independently of Lamin A/C AIDS (London, England). Oct, 2005 | Pubmed ID: 16184025 Nuclear Tumor Suppressors in Space and Time Trends in Cell Biology. Jul, 2005 | Pubmed ID: 15936946 LMNA Mutations in Progeroid Syndromes Novartis Foundation Symposium. 2005 | Pubmed ID: 15773755 Genes Determining Yeast Replicative Life Span in a Long-lived Genetic Background Mechanisms of Ageing and Development. Apr, 2005 | Pubmed ID: 15722108 A-type Nuclear Lamins, Progerias and Other Degenerative Disorders Mechanisms of Ageing and Development. Apr, 2005 | Pubmed ID: 15722103 Substrate-specific Activation of Sirtuins by Resveratrol The Journal of Biological Chemistry. Apr, 2005 | Pubmed ID: 15684413 Large-scale Identification in Yeast of Conserved Ageing Genes Mechanisms of Ageing and Development. Jan, 2005 | Pubmed ID: 15610758 Sir2-independent Life Span Extension by Calorie Restriction in Yeast PLoS Biology. Sep, 2004 | Pubmed ID: 15328540 A-type Lamins Regulate Retinoblastoma Protein Function by Promoting Subnuclear Localization and Preventing Proteasomal Degradation Proceedings of the National Academy of Sciences of the United States of America. Jun, 2004 | Pubmed ID: 15210943 Nuclear Reorganization of Mammalian DNA Synthesis Prior to Cell Cycle Exit Molecular and Cellular Biology. Jan, 2004 | Pubmed ID: 14701733 LMNA Mutations in Atypical Werner's Syndrome Lancet. Aug, 2003 | Pubmed ID: 12927431 Mammalian Transcription Factors in Yeast: Strangers in a Familiar Land Nature Reviews. Molecular Cell Biology. Jan, 2002 | Pubmed ID: 11823797 Medição Span vida replicativa na levedura de brotamento Kristan K. Steffen1, Brian K. Kennedy1, Matt Kaeberlein2 1Department of Biochemistry, University of Washington, 2Department of Pathology, University of Washington JoVE 1209 Biology
Medição Span vida replicativa na levedura de brotamento Kristan K. Steffen1, Brian K. Kennedy1, Matt Kaeberlein2 1Department of Biochemistry, University of Washington, 2Department of Pathology, University of Washington JoVE 1209 Biology