Brian M. Zeglis Department of Chemistry Hunter College of the City University of New York Biography Publications Institution JoVE Articles Brian M. Zeglis has not added a biography. If you are Brian M. Zeglis and would like to personalize this page please email our Author Liaison for assistance. Publications Leveraging Bioorthogonal Click Chemistry to Improve Ac-Radioimmunotherapy of Pancreatic Ductal Adenocarcinoma Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jan, 2019 | Pubmed ID: 30352909 Pretargeted Imaging and Therapy Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 10, 2017 | Pubmed ID: 28687600 ESPMIS: Helping Young Scientists Navigate the Molecular Imaging Landscape Molecular Imaging and Biology : MIB : the Official Publication of the Academy of Molecular Imaging. Feb, 2017 | Pubmed ID: 28194633 Establishment of the In Vivo Efficacy of Pretargeted Radioimmunotherapy Utilizing Inverse Electron Demand Diels-Alder Click Chemistry Molecular Cancer Therapeutics. Jan, 2017 | Pubmed ID: 28062708 A Pretargeted Approach for the Multimodal PET/NIRF Imaging of Colorectal Cancer Theranostics. Month, 2016 | Pubmed ID: 27924162 Click Chemistry and Radiochemistry: The First 10 Years Bioconjugate Chemistry. Dec, 2016 | Pubmed ID: 27787983 A Bone-Seeking Trans-Cyclooctene for Pretargeting and Bioorthogonal Chemistry: A Proof of Concept Study Using (99m)Tc- and (177)Lu-Labeled Tetrazines Journal of Medicinal Chemistry. Oct, 2016 | Pubmed ID: 27676258 Near-Infrared Intraoperative Chemiluminescence Imaging ChemMedChem. Sep, 2016 | Pubmed ID: 27471800 A Comparative Evaluation of the Chelators H4octapa and CHX-A″-DTPA with the Therapeutic Radiometal (90)Y Nuclear Medicine and Biology. Sep, 2016 | Pubmed ID: 27419360 Pretargeted PET Imaging Using a Site-Specifically Labeled Immunoconjugate Bioconjugate Chemistry. Aug, 2016 | Pubmed ID: 27356886 Molecular Imaging of Ovarian Cancer Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Jun, 2016 | Pubmed ID: 27127223 Preclinical 89Zr Immuno-PET of High-Grade Serous Ovarian Cancer and Lymph Node Metastasis Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. May, 2016 | Pubmed ID: 26837339 Site-Specifically Labeled Immunoconjugates for Molecular Imaging--Part 2: Peptide Tags and Unnatural Amino Acids Molecular Imaging and Biology : MIB : the Official Publication of the Academy of Molecular Imaging. Apr, 2016 | Pubmed ID: 26754791 Site-Specifically Labeled Immunoconjugates for Molecular Imaging--Part 1: Cysteine Residues and Glycans Molecular Imaging and Biology : MIB : the Official Publication of the Academy of Molecular Imaging. Feb, 2016 | Pubmed ID: 26754790 (18)F-Based Pretargeted PET Imaging Based on Bioorthogonal Diels-Alder Click Chemistry Bioconjugate Chemistry. Feb, 2016 | Pubmed ID: 26479967 Pretargeted Immuno-PET of Pancreatic Cancer: Overcoming Circulating Antigen and Internalized Antibody to Reduce Radiation Doses Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Mar, 2016 | Pubmed ID: 26471693 Site-specifically Labeled CA19.9-targeted Immunoconjugates for the PET, NIRF, and Multimodal PET/NIRF Imaging of Pancreatic Cancer Proceedings of the National Academy of Sciences of the United States of America. Dec, 2015 | Pubmed ID: 26668398 Optimization of a Pretargeted Strategy for the PET Imaging of Colorectal Carcinoma Via the Modulation of Radioligand Pharmacokinetics Molecular Pharmaceutics. Oct, 2015 | Pubmed ID: 26287993 Chemoenzymatic Strategy for the Synthesis of Site-specifically Labeled Immunoconjugates for Multimodal PET and Optical Imaging Bioconjugate Chemistry. Dec, 2014 | Pubmed ID: 25418333 Synthesis and Evaluation of (18)F-labeled ATP Competitive Inhibitors of Topoisomerase II As Probes for Imaging Topoisomerase II Expression European Journal of Medicinal Chemistry. Oct, 2014 | Pubmed ID: 25240701 What a Difference a Carbon Makes: H₄octapa Vs H₄C3octapa, Ligands for In-111 and Lu-177 Radiochemistry Inorganic Chemistry. Oct, 2014 | Pubmed ID: 25192223 Synthesis of the First Radiolabeled 188Re N-heterocyclic Carbene Complex and Initial Studies on Its Potential Use in Radiopharmaceutical Applications Journal of Labelled Compounds & Radiopharmaceuticals. Jun, 2014 | Pubmed ID: 24889257 Alternative Chelator for ⁸⁹Zr Radiopharmaceuticals: Radiolabeling and Evaluation of 3,4,3-(LI-1,2-HOPO) Journal of Medicinal Chemistry. Jun, 2014 | Pubmed ID: 24814511 Building Blocks for the Construction of Bioorthogonally Reactive Peptides Via Solid-Phase Peptide Synthesis ChemistryOpen. Apr, 2014 | Pubmed ID: 24808990 The Inverse Electron Demand Diels-Alder Click Reaction in Radiochemistry Journal of Labelled Compounds & Radiopharmaceuticals. Apr, 2014 | Pubmed ID: 24347429 Underscoring the Influence of Inorganic Chemistry on Nuclear Imaging with Radiometals Inorganic Chemistry. Feb, 2014 | Pubmed ID: 24313747 H6phospa-trastuzumab: Bifunctional Methylenephosphonate-based Chelator with 89Zr, 111In and 177Lu Dalton Transactions (Cambridge, England : 2003). Jan, 2014 | Pubmed ID: 24104523 H(4)octapa-trastuzumab: Versatile Acyclic Chelate System for 111In and 177Lu Imaging and Therapy Journal of the American Chemical Society. Aug, 2013 | Pubmed ID: 23901833 A Pretargeted PET Imaging Strategy Based on Bioorthogonal Diels-Alder Click Chemistry Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Aug, 2013 | Pubmed ID: 23708196 Enzyme-mediated Methodology for the Site-specific Radiolabeling of Antibodies Based on Catalyst-free Click Chemistry Bioconjugate Chemistry. Jun, 2013 | Pubmed ID: 23688208 The Growing Impact of Bioorthogonal Click Chemistry on the Development of Radiopharmaceuticals Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Jun, 2013 | Pubmed ID: 23616581 PET Imaging with ⁸⁹Zr: from Radiochemistry to the Clinic Nuclear Medicine and Biology. Jan, 2013 | Pubmed ID: 22998840 H(2)azapa: a Versatile Acyclic Multifunctional Chelator for (67)Ga, (64)Cu, (111)In, and (177)Lu Inorganic Chemistry. Nov, 2012 | Pubmed ID: 23106422 Modular Strategy for the Construction of Radiometalated Antibodies for Positron Emission Tomography Based on Inverse Electron Demand Diels-Alder Click Chemistry Bioconjugate Chemistry. Oct, 2011 | Pubmed ID: 21877749 The Synthesis and Evaluation of N1-(4-(2-[18F]-fluoroethyl)phenyl)-N8-hydroxyoctanediamide ([18F]-FESAHA), a PET Radiotracer Designed for the Delineation of Histone Deacetylase Expression in Cancer Nuclear Medicine and Biology. Jul, 2011 | Pubmed ID: 21718944 A Practical Guide to the Construction of Radiometallated Bioconjugates for Positron Emission Tomography Dalton Transactions (Cambridge, England : 2003). Jun, 2011 | Pubmed ID: 21442098 Role of Metalation in the Topoisomerase IIα Inhibition and Antiproliferation Activity of a Series of α-heterocyclic-N4-substituted Thiosemicarbazones and Their Cu(II) Complexes Journal of Medicinal Chemistry. Apr, 2011 | Pubmed ID: 21391686 A Bulky Rhodium Complex Bound to an Adenosine-adenosine DNA Mismatch: General Architecture of the Metalloinsertion Binding Mode Biochemistry. May, 2009 | Pubmed ID: 19374348 Recognition of Abasic Sites and Single Base Bulges in DNA by a Metalloinsertor Biochemistry. Feb, 2009 | Pubmed ID: 19146409 Binding of Ru(bpy)2(eilatin)2+ to Matched and Mismatched DNA Inorganic Chemistry. Jul, 2008 | Pubmed ID: 18576614 Targeting Abasic Sites and Single Base Bulges in DNA with Metalloinsertors Journal of the American Chemical Society. Jun, 2008 | Pubmed ID: 18491905 Metallo-intercalators and Metallo-insertors Chemical Communications (Cambridge, England). Nov, 2007 | Pubmed ID: 17989802 DNA Base Mismatch Detection with Bulky Rhodium Intercalators: Synthesis and Applications Nature Protocols. Month, 2007 | Pubmed ID: 17406597 A Mismatch-selective Bifunctional Rhodium-Oregon Green Conjugate: a Fluorescent Probe for Mismatched DNA Journal of the American Chemical Society. May, 2006 | Pubmed ID: 16637630 Unexpected Oxidative C-C Cleavage in the Metallation of 2-substituted Imidazolium Salts to Give N-heterocyclic Carbene Complexes Chemical Communications (Cambridge, England). Oct, 2004 | Pubmed ID: 15467859 סינתזה, Bioconjugation של תיול-תגובתי ריאגנטים עבור הקמת האתר באופן סלקטיבי שונה Immunoconjugates Maria Davydova1, Guillaume Dewaele Le Roi1,2, Pierre Adumeau1, Brian M. Zeglis1,2,3,4 1Department of Chemistry, Hunter College of the City University of New York, 2Ph.D. Program in Chemistry, Graduate Center of the City University of New York, 3Department of Radiology, Memorial Sloan Kettering Cancer Center, 4Department of Radiology, Weill Cornell Medical College JoVE 59063 Chemistry Radioimmunotherapy pretargeted התגובה תגובת דילס-אלדר דרישה אלקטרון הופכי Rosemery Membreno1,2, Brendon E. Cook1,2,3, Brian M. Zeglis1,2,3,4 1Department of Chemistry, Hunter College of the City University of New York, 2Ph.D. Program in Chemistry, Graduate Center of the City University of New York, 3Department of Radiology, Memorial Sloan Kettering Cancer Center, 4Department of Radiology, Weill Cornell Medical College JoVE 59041 Chemistry שיטה חדשנית עבור chemiluminescence יצירה וההתבוננות בסביבה ביולוגית Gabriel E. Büchel1,2, Brandon Carney1,3, Jun Tang1, Brian M. Zeglis1,3, Jörg Eppinger2, Thomas Reiner1,4 1Department of Radiology, Memorial Sloan Kettering Cancer Center, 2KAUST Catalysis Center, King Abdullah University of Science and Technology, 3Department of Chemistry, Hunter College, and PhD Program in Chemistry, Graduate Center of City University of New York, 4Department of Radiology, Weill Cornell Medical College Bioengineering Bioconjugation וRadiosynthesis של Brian M. Zeglis1, Jason S. Lewis1 1Department of Radiology, Memorial Sloan Kettering Cancer Center Chemistry רתימת ביקוש Bioorthogonal הפוך אלקטרונים דילס-Alder cycloaddition לPretargeted PET הדמיה Thomas Reiner*1, Jason S. Lewis1, Brian M. Zeglis*1 1Department of Radiology, Memorial Sloan Kettering Cancer Center Bioengineering
סינתזה, Bioconjugation של תיול-תגובתי ריאגנטים עבור הקמת האתר באופן סלקטיבי שונה Immunoconjugates Maria Davydova1, Guillaume Dewaele Le Roi1,2, Pierre Adumeau1, Brian M. Zeglis1,2,3,4 1Department of Chemistry, Hunter College of the City University of New York, 2Ph.D. Program in Chemistry, Graduate Center of the City University of New York, 3Department of Radiology, Memorial Sloan Kettering Cancer Center, 4Department of Radiology, Weill Cornell Medical College JoVE 59063 Chemistry
Radioimmunotherapy pretargeted התגובה תגובת דילס-אלדר דרישה אלקטרון הופכי Rosemery Membreno1,2, Brendon E. Cook1,2,3, Brian M. Zeglis1,2,3,4 1Department of Chemistry, Hunter College of the City University of New York, 2Ph.D. Program in Chemistry, Graduate Center of the City University of New York, 3Department of Radiology, Memorial Sloan Kettering Cancer Center, 4Department of Radiology, Weill Cornell Medical College JoVE 59041 Chemistry
שיטה חדשנית עבור chemiluminescence יצירה וההתבוננות בסביבה ביולוגית Gabriel E. Büchel1,2, Brandon Carney1,3, Jun Tang1, Brian M. Zeglis1,3, Jörg Eppinger2, Thomas Reiner1,4 1Department of Radiology, Memorial Sloan Kettering Cancer Center, 2KAUST Catalysis Center, King Abdullah University of Science and Technology, 3Department of Chemistry, Hunter College, and PhD Program in Chemistry, Graduate Center of City University of New York, 4Department of Radiology, Weill Cornell Medical College Bioengineering
Bioconjugation וRadiosynthesis של Brian M. Zeglis1, Jason S. Lewis1 1Department of Radiology, Memorial Sloan Kettering Cancer Center Chemistry
רתימת ביקוש Bioorthogonal הפוך אלקטרונים דילס-Alder cycloaddition לPretargeted PET הדמיה Thomas Reiner*1, Jason S. Lewis1, Brian M. Zeglis*1 1Department of Radiology, Memorial Sloan Kettering Cancer Center Bioengineering
