Brian Seed

Publications

• Enhanced Tim3 Activity Improves Survival After Influenza Infection
  Journal of Immunology (Baltimore, Md. : 1950). Sep, 2012  |   Pubmed ID: 22875804
• STAT6 Phosphorylation Inhibitors Block Eotaxin-3 Secretion in Bronchial Epithelial Cells
  Bioorganic & Medicinal Chemistry. Jan, 2012  |   Pubmed ID: 22217933
• PrimerBank: a PCR Primer Database for Quantitative Gene Expression Analysis, 2012 Update
  Nucleic Acids Research. Jan, 2012  |   Pubmed ID: 22086960
• Phosphoprotein Associated with Glycosphingolipid-enriched Microdomains Differentially Modulates SRC Kinase Activity in Brain Maturation
  PloS One. 2011  |   Pubmed ID: 21915273
• C-aryl Glucosides Substituted at the 4'-position As Potent and Selective Renal Sodium-dependent Glucose Co-transporter 2 (SGLT2) Inhibitors for the Treatment of Type 2 Diabetes
  Bioorganic & Medicinal Chemistry Letters. Aug, 2011  |   Pubmed ID: 21737266
• EGT1442, a Potent and Selective SGLT2 Inhibitor, Attenuates Blood Glucose and HbA(1c) Levels in Db/db Mice and Prolongs the Survival of Stroke-prone Rats
  Pharmacological Research : the Official Journal of the Italian Pharmacological Society. Apr, 2011  |   Pubmed ID: 21215314
• The Transcription Factor MafB Antagonizes Antiviral Responses by Blocking Recruitment of Coactivators to the Transcription Factor IRF3
  Nature Immunology. Aug, 2010  |   Pubmed ID: 20581830
• Ortho-Substituted C-aryl Glucosides As Highly Potent and Selective Renal Sodium-dependent Glucose Co-transporter 2 (SGLT2) Inhibitors
  Bioorganic & Medicinal Chemistry. Jun, 2010  |   Pubmed ID: 20576578
• Mice Lacking Dok-1, Dok-2, and Dok-3 Succumb to Aggressive Histiocytic Sarcoma
  Laboratory Investigation; a Journal of Technical Methods and Pathology. Sep, 2010  |   Pubmed ID: 20548287
• Activating WASP Mutations Associated with X-linked Neutropenia Result in Enhanced Actin Polymerization, Altered Cytoskeletal Responses, and Genomic Instability in Lymphocytes
  The Journal of Experimental Medicine. Jun, 2010  |   Pubmed ID: 20513746
• Conformationally Constrained Spiro C-arylglucosides As Potent and Selective Renal Sodium-dependent Glucose Co-transporter 2 (SGLT2) Inhibitors
  ChemMedChem. Jun, 2010  |   Pubmed ID: 20414917
• Host-encoded Reporters for the Detection and Purification of Multiple Enveloped Viruses
  Journal of Virological Methods. Aug, 2010  |   Pubmed ID: 20399809
• Fluorosomes: a Convenient New Reagent to Detect and Block Multivalent and Complex Receptor-ligand Interactions
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. May, 2010  |   Pubmed ID: 20056716
• PrimerBank: a Resource of Human and Mouse PCR Primer Pairs for Gene Expression Detection and Quantification
  Nucleic Acids Research. Jan, 2010  |   Pubmed ID: 19906719
• Exploration of O-spiroketal C-arylglucosides As Novel and Selective Renal Sodium-dependent Glucose Co-transporter 2 (SGLT2) Inhibitors
  Bioorganic & Medicinal Chemistry Letters. Dec, 2009  |   Pubmed ID: 19896374
• O-Spiro C-aryl Glucosides As Novel Sodium-dependent Glucose Co-transporter 2 (SGLT2) Inhibitors
  Bioorganic & Medicinal Chemistry Letters. Oct, 2009  |   Pubmed ID: 19700318
• Modulation of Allergen-specific T-lymphocyte Function by Virus-like Particles Decorated with HLA Class II Molecules
  The Journal of Allergy and Clinical Immunology. Jul, 2009  |   Pubmed ID: 19500826
• Lack of Lymphatic Vessel Phenotype in LYVE-1/CD44 Double Knockout Mice
  Journal of Cellular Physiology. May, 2009  |   Pubmed ID: 19170073
• A Comprehensive Collection of Experimentally Validated Primers for Polymerase Chain Reaction Quantitation of Murine Transcript Abundance
  BMC Genomics. 2008  |   Pubmed ID: 19108745
• Quantitation of Autophagy by Luciferase Release Assay
  Autophagy. Aug, 2008  |   Pubmed ID: 18641457
• Spinophilin and the Immune Synapse
  The Journal of Cell Biology. Apr, 2008  |   Pubmed ID: 18411314
• A Pathway Sensor for Genome-wide Screens of Intracellular Proteolytic Cleavage
  Genome Biology. 2008  |   Pubmed ID: 18387192
• A Novel Sorting Nexin Modulates Endocytic Trafficking and Alpha-secretase Cleavage of the Amyloid Precursor Protein
  The Journal of Biological Chemistry. May, 2008  |   Pubmed ID: 18353773
• Molecular and Functional Analysis of the Antigen Receptor of Art V 1-specific Helper T Lymphocytes
  The Journal of Allergy and Clinical Immunology. Jan, 2008  |   Pubmed ID: 18037161
• General Strategy for Decoration of Enveloped Viruses with Functionally Active Lipid-modified Cytokines
  Journal of Virology. Aug, 2007  |   Pubmed ID: 17537846
• ABCA3 Inactivation in Mice Causes Respiratory Failure, Loss of Pulmonary Surfactant, and Depletion of Lung Phosphatidylglycerol
  Journal of Lipid Research. Mar, 2007  |   Pubmed ID: 17142808
• Direct Stimulation of T Lymphocytes by Immunosomes: Virus-like Particles Decorated with T Cell Receptor/CD3 Ligands Plus Costimulatory Molecules
  Proceedings of the National Academy of Sciences of the United States of America. Aug, 2006  |   Pubmed ID: 16924110
• A Sequence-oriented Comparison of Gene Expression Measurements Across Different Hybridization-based Technologies
  Nature Biotechnology. Jul, 2006  |   Pubmed ID: 16823376
• CARMA1 is Critical for the Development of Allergic Airway Inflammation in a Murine Model of Asthma
  Journal of Immunology (Baltimore, Md. : 1950). Jun, 2006  |   Pubmed ID: 16751370
• Expression Cloning Screen for Modifiers of Amyloid Precursor Protein Shedding
  International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience. Apr-May, 2006  |   Pubmed ID: 16446073
• B Cell Maturation Antigen, the Receptor for a Proliferation-inducing Ligand and B Cell-activating Factor of the TNF Family, Induces Antigen Presentation in B Cells
  Journal of Immunology (Baltimore, Md. : 1950). Sep, 2005  |   Pubmed ID: 16116167
• Large-scale Screens for CDNAs with in Vivo Activity
  Novartis Foundation Symposium. 2005  |   Pubmed ID: 15999809
• PDZ Domains and the Politics of Polarity in Lymphocytes
  Immunity. Jun, 2005  |   Pubmed ID: 15963778
• Identification of Eosinophil Lineage-committed Progenitors in the Murine Bone Marrow
  The Journal of Experimental Medicine. Jun, 2005  |   Pubmed ID: 15955840
• Differential Transplantability of Tumor-associated Stromal Cells
  Cancer Research. Sep, 2004  |   Pubmed ID: 15342367
• The Knockout Mouse Project
  Nature Genetics. Sep, 2004  |   Pubmed ID: 15340423
• Discs Large (Dlg1) Complexes in Lymphocyte Activation
  The Journal of Cell Biology. Jul, 2004  |   Pubmed ID: 15263016
• The Scaffold Protein CNK1 Interacts with the Tumor Suppressor RASSF1A and Augments RASSF1A-induced Cell Death
  The Journal of Biological Chemistry. Jul, 2004  |   Pubmed ID: 15075335
• Epstein-Barr Virus Latent Infection Membrane Protein 1 TRAF-binding Site Induces NIK/IKK Alpha-dependent Noncanonical NF-kappaB Activation
  Proceedings of the National Academy of Sciences of the United States of America. Jan, 2004  |   Pubmed ID: 14691250
• A PCR Primer Bank for Quantitative Gene Expression Analysis
  Nucleic Acids Research. Dec, 2003  |   Pubmed ID: 14654707
• The Cell Adhesion Protein P-selectin Glycoprotein Ligand-1 is a Substrate for the Aspartyl Protease BACE1
  The Journal of Biological Chemistry. Dec, 2003  |   Pubmed ID: 14507929
• Dynamic Imaging of Collagen and Its Modulation in Tumors in Vivo Using Second-harmonic Generation
  Nature Medicine. Jun, 2003  |   Pubmed ID: 12754503
• Selection of Oligonucleotide Probes for Protein Coding Sequences
  Bioinformatics (Oxford, England). May, 2003  |   Pubmed ID: 12724288
• Site-specific Gene Targeting in Mouse Embryonic Stem Cells with Intact Bacterial Artificial Chromosomes
  Nature Biotechnology. Apr, 2003  |   Pubmed ID: 12627171
• Identification of a Novel Ras-regulated Proapoptotic Pathway
  Current Biology : CB. Feb, 2002  |   Pubmed ID: 11864565