Brian Slaughter Stowers Institute for Medical Research Biography Publications Institution JoVE Articles Brian Slaughter has not added a biography. If you are Brian Slaughter and would like to personalize this page please email our Author Liaison for assistance. Publications Repeated Evolution of Circadian Clock Dysregulation in Cavefish Populations PLoS Genetics. Jul, 2021 | Pubmed ID: 34252077 A Role for the Cockayne Syndrome B (CSB)-Elongin Ubiquitin Ligase Complex in Signal-dependent RNA Polymerase II Transcription The Journal of Biological Chemistry. 07, 2021 | Pubmed ID: 34116057 Super-resolution Microscopy-based Bimolecular Fluorescence Complementation to Study Protein Complex Assembly and Co-localization Bio-protocol. Feb, 2020 | Pubmed ID: 33654748 Driving Integrative Structural Modeling with Serial Capture Affinity Purification Proceedings of the National Academy of Sciences of the United States of America. 12, 2020 | Pubmed ID: 33257578 Adaptation to Low Parasite Abundance Affects Immune Investment and Immunopathological Responses of Cavefish Nature Ecology & Evolution. 10, 2020 | Pubmed ID: 32690906 Amyloid-like Assembly Activates a Phosphatase in the Developing Drosophila Embryo Cell. 09, 2019 | Pubmed ID: 31491385 The Stoichiometry of the Outer Kinetochore is Modulated by Microtubule-proximal Regulatory Factors The Journal of Cell Biology. 07, 2019 | Pubmed ID: 31118239 Yeast Centrosome Components Form a Noncanonical LINC Complex at the Nuclear Envelope Insertion Site The Journal of Cell Biology. 05, 2019 | Pubmed ID: 30862629 Imaging-based Assays for Investigating Functions of the RNA Polymerase II Elongation Factor Elongin and the Elongin Ubiquitin Ligase Methods (San Diego, Calif.). Feb, 2019 | Pubmed ID: 30794906 Functional Analysis of the Yeast LINC Complex Using Fluctuation Spectroscopy and Super-Resolution Imaging Methods in Molecular Biology (Clifton, N.J.). 2018 | Pubmed ID: 30141044 Combined Expansion Microscopy with Structured Illumination Microscopy for Analyzing Protein Complexes Nature Protocols. 08, 2018 | Pubmed ID: 30072723 The Anatomy of a Nucleus: As Revealed by Chromosome Painting PLoS Genetics. 07, 2018 | Pubmed ID: 30001330 Integrative Structure and Functional Anatomy of a Nuclear Pore Complex Nature. 03, 2018 | Pubmed ID: 29539637 Structural Plasticity of the Living Kinetochore The Journal of Cell Biology. 11, 2017 | Pubmed ID: 28939613 HOXA1 and TALE Proteins Display Cross-regulatory Interactions and Form a Combinatorial Binding Code on HOXA1 Targets Genome Research. 09, 2017 | Pubmed ID: 28784834 Superresolution Expansion Microscopy Reveals the Three-dimensional Organization of the Synaptonemal Complex Proceedings of the National Academy of Sciences of the United States of America. 08, 2017 | Pubmed ID: 28760978 Condensin II is Anchored by TFIIIC and H3K4me3 in the Mammalian Genome and Supports the Expression of Active Dense Gene Clusters Science Advances. 06, 2017 | Pubmed ID: 28691095 Dynamic Regulation of Nanog and Stem Cell-signaling Pathways by Hoxa1 During Early Neuro-ectodermal Differentiation of ES Cells Proceedings of the National Academy of Sciences of the United States of America. 06, 2017 | Pubmed ID: 28584089 Analysis of Membrane Proteins Localizing to the Inner Nuclear Envelope in Living Cells The Journal of Cell Biology. Nov, 2016 | Pubmed ID: 27831485 A Putative Biochemical Engram of Long-Term Memory Current Biology : CB. 12, 2016 | Pubmed ID: 27818176 WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage PloS One. 2016 | Pubmed ID: 27248496 Molecular Basis of Orb2 Amyloidogenesis and Blockade of Memory Consolidation PLoS Biology. Jan, 2016 | Pubmed ID: 26812143 Karyotyping Human and Mouse Cells Using Probes from Single-sorted Chromosomes and Open Source Software BioTechniques. Dec, 2015 | Pubmed ID: 26651513 Amyloidogenic Oligomerization Transforms Drosophila Orb2 from a Translation Repressor to an Activator Cell. Dec, 2015 | Pubmed ID: 26638074 Mitotic Transcriptional Activation: Clearance of Actively Engaged Pol II Via Transcriptional Elongation Control in Mitosis Molecular Cell. Nov, 2015 | Pubmed ID: 26527278 Sec66-Dependent Regulation of Yeast Spindle-Pole Body Duplication Through Pom152 Genetics. Dec, 2015 | Pubmed ID: 26510791 Vilya, a Component of the Recombination Nodule, is Required for Meiotic Double-strand Break Formation in Drosophila ELife. Oct, 2015 | Pubmed ID: 26452093 Structured Illumination with Particle Averaging Reveals Novel Roles for Yeast Centrosome Components During Duplication ELife. Sep, 2015 | Pubmed ID: 26371506 Analysis of Dynamic Changes in Retinoid-induced Transcription and Epigenetic Profiles of Murine Hox Clusters in ES Cells Genome Research. Aug, 2015 | Pubmed ID: 26025802 Imaging Methodologies for Systems Biology Cell Adhesion & Migration. 2014 | Pubmed ID: 25482526 Organelle-based Aggregation and Retention of Damaged Proteins in Asymmetrically Dividing Cells Cell. Oct, 2014 | Pubmed ID: 25417105 The Membrane-associated Proteins FCHo and SGIP Are Allosteric Activators of the AP2 Clathrin Adaptor Complex ELife. Oct, 2014 | Pubmed ID: 25303366 Corolla is a Novel Protein That Contributes to the Architecture of the Synaptonemal Complex of Drosophila Genetics. Sep, 2014 | Pubmed ID: 24913682 The SUN Protein Mps3 Controls Ndc1 Distribution and Function on the Nuclear Membrane The Journal of Cell Biology. Feb, 2014 | Pubmed ID: 24515347 Cohesion Promotes Nucleolar Structure and Function Molecular Biology of the Cell. Feb, 2014 | Pubmed ID: 24307683 Independence of Symmetry Breaking on Bem1-mediated Autocatalytic Activation of Cdc42 The Journal of Cell Biology. Sep, 2013 | Pubmed ID: 24062340 Binding of Drosophila Polo Kinase to Its Regulator Matrimony is Noncanonical and Involves Two Separate Functional Domains Proceedings of the National Academy of Sciences of the United States of America. Mar, 2013 | Pubmed ID: 23479640 Sequential Actin-based Pushing Forces Drive Meiosis I Chromosome Migration and Symmetry Breaking in Oocytes The Journal of Cell Biology. Mar, 2013 | Pubmed ID: 23439682 Quality Control: Putting Protein Aggregates in a Bind Current Biology : CB. Jan, 2013 | Pubmed ID: 23347944 Non-uniform Membrane Diffusion Enables Steady-state Cell Polarization Via Vesicular Trafficking Nature Communications. Jan, 2013 | Pubmed ID: 23340420 Genetic Analysis of Mps3 SUN Domain Mutants in Saccharomyces Cerevisiae Reveals an Interaction with the SUN-like Protein Slp1 G3 (Bethesda, Md.). Dec, 2012 | Pubmed ID: 23275891 Weakly Nonlinear Analysis of Symmetry Breaking in Cell Polarity Models Physical Biology. Aug, 2012 | Pubmed ID: 22871896 Cell-cycle-coupled Structural Oscillation of Centromeric Nucleosomes in Yeast Cell. Jul, 2012 | Pubmed ID: 22817893 Cohesin Proteins Promote Ribosomal RNA Production and Protein Translation in Yeast and Human Cells PLoS Genetics. 2012 | Pubmed ID: 22719263 Acetylation of the SUN Protein Mps3 by Eco1 Regulates Its Function in Nuclear Organization Molecular Biology of the Cell. Jul, 2012 | Pubmed ID: 22593213 Flippase-mediated Phospholipid Asymmetry Promotes Fast Cdc42 Recycling in Dynamic Maintenance of Cell polarity Nature Cell Biology. Feb, 2012 | Pubmed ID: 22344035 Critical Role of Amyloid-like Oligomers of Drosophila Orb2 in the Persistence of Memory Cell. Feb, 2012 | Pubmed ID: 22284910 The SUN Protein Mps3 is Required for Spindle Pole Body Insertion into the Nuclear Membrane and Nuclear Envelope Homeostasis PLoS Genetics. Nov, 2011 | Pubmed ID: 22125491 Motility and Segregation of Hsp104-associated Protein Aggregates in Budding Yeast Cell. Nov, 2011 | Pubmed ID: 22118470 Dynamic Maintenance of Asymmetric Meiotic Spindle Position Through Arp2/3-complex-driven Cytoplasmic Streaming in Mouse Oocytes Nature Cell Biology. Aug, 2011 | Pubmed ID: 21874009 Fluorescence Fluctuation Spectroscopy and Imaging Methods for Examination of Dynamic Protein Interactions in Yeast Methods in Molecular Biology (Clifton, N.J.). 2011 | Pubmed ID: 21863494 Gamma-tubulin is Required for Bipolar Spindle Assembly and for Proper Kinetochore Microtubule Attachments During Prometaphase I in Drosophila Oocytes PLoS Genetics. Aug, 2011 | Pubmed ID: 21852952 Toward Quantitative "in Vivo Biochemistry" with Fluorescence Fluctuation Spectroscopy Molecular Biology of the Cell. Dec, 2010 | Pubmed ID: 21160072 Symmetry Breaking in the Life Cycle of the Budding Yeast Cold Spring Harbor Perspectives in Biology. Sep, 2009 | Pubmed ID: 20066112 Dual Modes of Cdc42 Recycling Fine-tune Polarized Morphogenesis Developmental Cell. Dec, 2009 | Pubmed ID: 20059952 SAM Domain-based Protein Oligomerization Observed by Live-cell Fluorescence Fluctuation Spectroscopy PloS One. Apr, 2008 | Pubmed ID: 18431466 Mapping Dynamic Protein Interactions in MAP Kinase Signaling Using Live-cell Fluorescence Fluctuation Spectroscopy and Imaging Proceedings of the National Academy of Sciences of the United States of America. Dec, 2007 | Pubmed ID: 18077328 Toward a Molecular Interpretation of the Surface Stress Theory for Yeast Morphogenesis Current Opinion in Cell Biology. Feb, 2006 | Pubmed ID: 16337116 Planarian Ovary Dissection for Ultrastructural Analysis and Antibody Staining Fengli Guo1, Melainia McClain1, Xia Zhao1, Kexi Yi1, Tari Parmely1, Jay Unruh1, Brian Slaughter1, Leonid Kruglyak2,3, Longhua Guo2,3, Alejandro Sánchez Alvarado1,2 1Stowers Institute for Medical Research, 2Howard Hughes Medical Institute, 3Department of Human Genetics, University of California Los Angeles JoVE 62713 Biology
Planarian Ovary Dissection for Ultrastructural Analysis and Antibody Staining Fengli Guo1, Melainia McClain1, Xia Zhao1, Kexi Yi1, Tari Parmely1, Jay Unruh1, Brian Slaughter1, Leonid Kruglyak2,3, Longhua Guo2,3, Alejandro Sánchez Alvarado1,2 1Stowers Institute for Medical Research, 2Howard Hughes Medical Institute, 3Department of Human Genetics, University of California Los Angeles JoVE 62713 Biology