C. Wayne Smith Children’s Nutrition Research Center Baylor College of Medicine Biography Publications Institution JoVE Articles C. Wayne Smith has not added a biography. If you are C. Wayne Smith and would like to personalize this page please email our Author Liaison for assistance. Publications Platelet and Erythrocyte Extravasation Across Inflamed Corneal Venules Depend on CD18, Neutrophils, and Mast Cell Degranulation International Journal of Molecular Sciences. Jul, 2021 | Pubmed ID: 34298979 Obese Mice with Dyslipidemia Exhibit Meibomian Gland Hypertrophy and Alterations in Meibum Composition and Aqueous Tear Production International Journal of Molecular Sciences. Nov, 2020 | Pubmed ID: 33233559 Corneal Dysfunction Precedes the Onset of Hyperglycemia in a Mouse Model of Diet-induced Obesity PloS One. 2020 | Pubmed ID: 32886728 Serial Block-face Scanning Electron Microscopy Reveals Neuronal-epithelial Cell Fusion in the Mouse Cornea PloS One. 2019 | Pubmed ID: 31721785 Dyslipidemia and Meibomian Gland Dysfunction: Utility of Lipidomics and Experimental Prospects with a Diet-Induced Obesity Mouse Model International Journal of Molecular Sciences. Jul, 2019 | Pubmed ID: 31319467 Regulation of the Ovarian Inflammatory Response at Ovulation by Nuclear Progesterone Receptor American Journal of Reproductive Immunology (New York, N.Y. : 1989). 06, 2018 | Pubmed ID: 29484756 IL-20 Promotes Epithelial Healing of the Injured Mouse Cornea Experimental Eye Research. 01, 2017 | Pubmed ID: 27818315 Ghrelin Receptor Regulates Adipose Tissue Inflammation in Aging Aging. Jan, 2016 | Pubmed ID: 26837433 Proinsulin-producing, Hyperglycemia-induced Adipose Tissue Macrophages Underlie Insulin Resistance in High Fat-fed Diabetic Mice FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Aug, 2015 | Pubmed ID: 25953849 Loss of N-6 Fatty Acid Induced Pediatric Obesity Protects Against Acute Murine Colitis FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Aug, 2015 | Pubmed ID: 25903104 Platelet Recruitment Promotes Keratocyte Repopulation Following Corneal Epithelial Abrasion in the Mouse PloS One. 2015 | Pubmed ID: 25775402 γδ T Cells Promote Inflammation and Insulin Resistance During High Fat Diet-induced Obesity in Mice Journal of Leukocyte Biology. Jan, 2015 | Pubmed ID: 25395302 Attenuated Adipose Tissue and Skeletal Muscle Inflammation in Obese Mice with Combined CD4+ and CD8+ T Cell Deficiency Atherosclerosis. Apr, 2014 | Pubmed ID: 24530773 Integrin-dependent Neutrophil Migration in the Injured Mouse Cornea Experimental Eye Research. Mar, 2014 | Pubmed ID: 24462632 Essential Role of CD11a in CD8+ T-cell Accumulation and Activation in Adipose Tissue Arteriosclerosis, Thrombosis, and Vascular Biology. Jan, 2014 | Pubmed ID: 24158516 CD11a Polymorphisms Regulate TH2 Cell Homing and TH2-related Disease The Journal of Allergy and Clinical Immunology. Jan, 2014 | Pubmed ID: 23726040 Dietary Oleic Acid Increases M2 Macrophages in the Mesenteric Adipose Tissue PloS One. 2013 | Pubmed ID: 24098682 Prenatal Methyl-donor Supplementation Augments Colitis in Young Adult Mice PloS One. 2013 | Pubmed ID: 23977377 NK Cells Are Necessary for Recovery of Corneal CD11c+ Dendritic Cells After Epithelial Abrasion Injury Journal of Leukocyte Biology. Aug, 2013 | Pubmed ID: 23695308 Histone Induced Platelet Aggregation is Inhibited by Normal Albumin Thrombosis Research. Jul, 2013 | Pubmed ID: 23673386 Cellulose Supplementation Early in Life Ameliorates Colitis in Adult Mice PloS One. 2013 | Pubmed ID: 23437211 Genome-wide Association Replicates the Association of Duffy Antigen Receptor for Chemokines (DARC) Polymorphisms with Serum Monocyte Chemoattractant Protein-1 (MCP-1) Levels in Hispanic Children Cytokine. Dec, 2012 | Pubmed ID: 23017229 ApoE and the Role of Very Low Density Lipoproteins in Adipose Tissue Inflammation Atherosclerosis. Aug, 2012 | Pubmed ID: 22770993 Expression of Interleukin-8 and Intercellular Cell Adhesion Molecule-1 in the Synovial Membrane and Cranial Cruciate Ligament of Dogs After Rupture of the Ligament Canadian Journal of Veterinary Research = Revue Canadienne De Recherche Veterinaire. Jan, 2012 | Pubmed ID: 22754089 NK Cells Modulate the Inflammatory Response to Corneal Epithelial Abrasion and Thereby Support Wound Healing The American Journal of Pathology. Aug, 2012 | Pubmed ID: 22728064 Wound Healing Characteristics of ICAM-1 Null Mice Devoid of All Isoforms of ICAM-1 The Journal of Surgical Research. Nov, 2011 | Pubmed ID: 21872884 Differential Effect of Weight Loss with Low-fat Diet or High-fat Diet Restriction on Inflammation in the Liver and Adipose Tissue of Mice with Diet-induced Obesity Atherosclerosis. Nov, 2011 | Pubmed ID: 21824616 Endothelium-derived GM-CSF Influences Expression of Oncostatin M American Journal of Physiology. Cell Physiology. Oct, 2011 | Pubmed ID: 21775705 CCL20, γδ T Cells, and IL-22 in Corneal Epithelial Healing FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Aug, 2011 | Pubmed ID: 21518851 IL-17 and VEGF Are Necessary for Efficient Corneal Nerve Regeneration The American Journal of Pathology. Mar, 2011 | Pubmed ID: 21356362 Maternal Methyl-donor Supplementation Induces Prolonged Murine Offspring Colitis Susceptibility in Association with Mucosal Epigenetic and Microbiomic Changes Human Molecular Genetics. May, 2011 | Pubmed ID: 21296867 Binding of Efb from Staphylococcus Aureus to Fibrinogen Blocks Neutrophil Adherence The Journal of Biological Chemistry. Mar, 2011 | Pubmed ID: 21247890 Colonic Mucosal DNA Methylation, Immune Response, and Microbiome Patterns in Toll-like Receptor 2-knockout Mice FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. May, 2011 | Pubmed ID: 21228220 Platelets Enhance Neutrophil Transendothelial Migration Via P-selectin Glycoprotein Ligand-1 American Journal of Physiology. Heart and Circulatory Physiology. Feb, 2011 | Pubmed ID: 21169400 Effect of the Cannabinoid Receptor-1 Antagonist Rimonabant on Inflammation in Mice with Diet-induced Obesity Obesity (Silver Spring, Md.). Mar, 2011 | Pubmed ID: 20885384 ICAM-1 Mediates Surface Contact Between Neutrophils and Keratocytes Following Corneal Epithelial Abrasion in the Mouse Experimental Eye Research. Nov, 2010 | Pubmed ID: 20713042 Early Differential Expression of Oncostatin M in Obstructive Nephropathy Journal of Interferon & Cytokine Research : the Official Journal of the International Society for Interferon and Cytokine Research. Jul, 2010 | Pubmed ID: 20626292 Epigenetic Maturation in Colonic Mucosa Continues Beyond Infancy in Mice Human Molecular Genetics. Jun, 2010 | Pubmed ID: 20197410 CD11c Expression in Adipose Tissue and Blood and Its Role in Diet-induced Obesity Arteriosclerosis, Thrombosis, and Vascular Biology. Feb, 2010 | Pubmed ID: 19910635 ICAM-1 is Necessary for Epithelial Recruitment of Gammadelta T Cells and Efficient Corneal Wound Healing The American Journal of Pathology. Aug, 2009 | Pubmed ID: 19608878 Functional Role of CD11c+ Monocytes in Atherogenesis Associated with Hypercholesterolemia Circulation. May, 2009 | Pubmed ID: 19433759 A Genetic Contribution to Circulating Cytokines and Obesity in Children Cytokine. Nov, 2008 | Pubmed ID: 18848781 Flow Cytometry on the Stromal-vascular Fraction of White Adipose Tissue Methods in Molecular Biology (Clifton, N.J.). 2008 | Pubmed ID: 18516564 Fetal Wound Healing Using a Genetically Modified Murine Model: the Contribution of P-selectin Journal of Pediatric Surgery. Apr, 2008 | Pubmed ID: 18405715 Developmental Control of Integrin Expression Regulates Th2 Effector Homing Journal of Immunology (Baltimore, Md. : 1950). Apr, 2008 | Pubmed ID: 18354189 Serum Amyloid P Inhibits Dermal Wound Healing Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society. Mar-Apr, 2008 | Pubmed ID: 18318811 3. Adhesion Molecules and Receptors The Journal of Allergy and Clinical Immunology. Feb, 2008 | Pubmed ID: 18241685 Neutrophil Interactions with Keratocytes During Corneal Epithelial Wound Healing: a Role for CD18 Integrins Investigative Ophthalmology & Visual Science. Nov, 2007 | Pubmed ID: 17962453 Gamma Delta T Cells Are Necessary for Platelet and Neutrophil Accumulation in Limbal Vessels and Efficient Epithelial Repair After Corneal Abrasion The American Journal of Pathology. Sep, 2007 | Pubmed ID: 17675580 T-cell Accumulation and Regulated on Activation, Normal T Cell Expressed and Secreted Upregulation in Adipose Tissue in Obesity Circulation. Feb, 2007 | Pubmed ID: 17296858 Transendothelial Migration Enhances Integrin-dependent Human Neutrophil Chemokinesis Journal of Leukocyte Biology. Mar, 2007 | Pubmed ID: 17164427 Lymphocyte Function-associated Antigen-1-dependent Inhibition of Corneal Wound Healing The American Journal of Pathology. Nov, 2006 | Pubmed ID: 17071583 ICAM-1 Expression in Adipose Tissue: Effects of Diet-induced Obesity in Mice American Journal of Physiology. Cell Physiology. Dec, 2006 | Pubmed ID: 16807303 Two Waves of Neutrophil Emigration in Response to Corneal Epithelial Abrasion: Distinct Adhesion Molecule Requirements Investigative Ophthalmology & Visual Science. May, 2006 | Pubmed ID: 16639002 Oncostatin M Differentially Regulates CXC Chemokines in Mouse Cardiac Fibroblasts American Journal of Physiology. Cell Physiology. Jul, 2006 | Pubmed ID: 16452159 Neutrophil Migration in the Wounded Cornea: the Role of the Keratocyte The Ocular Surface. Oct, 2005 | Pubmed ID: 17216113 Neutrophil Recruitment by Fetal Porcine Endothelial Cells: Implications in Scarless Fetal Wound Healing Pediatric Research. Dec, 2005 | Pubmed ID: 16306210 Neutrophils, Nitric Oxide, and Microvascular Permeability in Severe Sepsis Chest. Sep, 2005 | Pubmed ID: 16162778 Integrin Interactions with Immobilized Peptides in Polyethylene Glycol Diacrylate Hydrogels Tissue Engineering. Nov-Dec, 2004 | Pubmed ID: 15684686 Mouse Cremaster Venules Are Predisposed to Light/dye-induced Thrombosis Independent of Wall Shear Rate, CD18, ICAM-1, or P-selectin Microcirculation (New York, N.Y. : 1994). Apr-May, 2004 | Pubmed ID: 15280078 Leukocyte Migration in Adipose Tissue of Mice Null for ICAM-1 and Mac-1 Adhesion Receptors Obesity Research. Jun, 2004 | Pubmed ID: 15229332 Modulation of Inflammation by Slit Protein in Vivo in Experimental Crescentic Glomerulonephritis The American Journal of Pathology. Jul, 2004 | Pubmed ID: 15215188 Deficiency of CD11b or CD11d Results in Reduced Staphylococcal Enterotoxin-induced T Cell Response and T Cell Phenotypic Changes Journal of Immunology (Baltimore, Md. : 1950). Jul, 2004 | Pubmed ID: 15210787 Hindlimb Unloading Depresses Corneal Epithelial Wound Healing in Mice Journal of Applied Physiology (Bethesda, Md. : 1985). Aug, 2004 | Pubmed ID: 15064298 Cell Adhesion Molecules and Cytokines in Middle Ear Effusions in Children with or Without Recent Acute Otitis Media Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery. Feb, 2004 | Pubmed ID: 14990922 The Murine Myeloid Cell Line 32Dcl3 As a Model System for Studying Neutrophil Functions Journal of Immunological Methods. Dec, 2003 | Pubmed ID: 14659911 Differential Requirement for CD18 in T-helper Effector Homing Nature Medicine. Oct, 2003 | Pubmed ID: 14502280 Host Resistance of CD18 Knockout Mice Against Systemic Infection with Listeria Monocytogenes Infection and Immunity. Oct, 2003 | Pubmed ID: 14500519 Unique Structural Features That Influence Neutrophil Emigration into the Lung Physiological Reviews. Apr, 2003 | Pubmed ID: 12663861 Granulocyte Colony-stimulating Factor Promotes Adhesion of Neutrophils American Journal of Physiology. Cell Physiology. Jan, 2003 | Pubmed ID: 12388113 Vascular Cell Adhesion Molecule-1 Expression and Hematopoietic Supportive Capacity of Immortalized Murine Stromal Cell Lines Derived from Fetal Liver and Adult Bone Marrow In Vitro Cellular & Developmental Biology. Animal. Oct, 2002 | Pubmed ID: 12703982 Hydrodynamic Shear and Tethering Through E-selectin Signals Phosphorylation of P38 MAP Kinase and Adhesion of Human Neutrophils Annals of Biomedical Engineering. Sep, 2002 | Pubmed ID: 12449760 Mechanisms of Decreased Leukocyte Localization in the Developing Host American Journal of Physiology. Heart and Circulatory Physiology. Feb, 2002 | Pubmed ID: 11788413 The Inflammatory Response in Myocardial Infarction Cardiovascular Research. Jan, 2002 | Pubmed ID: 11744011 Role of P53-dependent Activation of Caspases in Chronic Obstructive Uropathy: Evidence from P53 Null Mutant Mice Journal of the American Society of Nephrology : JASN. May, 2001 | Pubmed ID: 11316857 Nonopsonic Binding of Type III Group B Streptococci to Human Neutrophils Induces Interleukin-8 Release Mediated by the P38 Mitogen-activated Protein Kinase Pathway Infection and Immunity. Apr, 2000 | Pubmed ID: 10722601 Characterization of the Priming Effect by Pituitary Canine Growth Hormone on Canine Polymorphonuclear Neutrophil Granulocyte Function Clinical and Diagnostic Laboratory Immunology. Mar, 2000 | Pubmed ID: 10702497 The Association Between Alpha4-integrin, P-selectin, and E-selectin in an Allergic Model of Inflammation The Journal of Experimental Medicine. Mar, 1997 | Pubmed ID: 9091581 An Epithelial Abrasion Model for Studying Corneal Wound Healing Prince K. Akowuah1, Angie De La Cruz1, C. Wayne Smith2, Rolando E. Rumbaut2,3, Alan R. Burns1,2 1College of Optometry, University of Houston, 2Children’s Nutrition Research Center, Baylor College of Medicine, 3Center for Translational Research on Inflammatory Diseases (CTRID), Michael E. DeBakey Veterans Affairs Medical Center JoVE 63112 Medicine
An Epithelial Abrasion Model for Studying Corneal Wound Healing Prince K. Akowuah1, Angie De La Cruz1, C. Wayne Smith2, Rolando E. Rumbaut2,3, Alan R. Burns1,2 1College of Optometry, University of Houston, 2Children’s Nutrition Research Center, Baylor College of Medicine, 3Center for Translational Research on Inflammatory Diseases (CTRID), Michael E. DeBakey Veterans Affairs Medical Center JoVE 63112 Medicine