Cameron S. Metcalf

Publications

• Precision Medicine for Genetic Epilepsy on the Horizon: Recent Advances, Present Challenges and Suggestions for Continued Progress
  Epilepsia. Jun, 2022  |   Pubmed ID: 35716052
• Anticonvulsive Properties of Soticlestat, a Novel Cholesterol 24-hydroxylase Inhibitor
  Epilepsia. Jun, 2022  |   Pubmed ID: 35316533
• Spontaneous Recurrent Seizures in an Intra-amygdala Kainate Microinjection Model of Temporal Lobe Epilepsy Are Differentially Sensitive to Antiseizure Drugs
  Experimental Neurology. 03, 2022  |   Pubmed ID: 34922908
• Screening of Prototype Antiseizure and Anti-inflammatory Compounds in the Theiler's Murine Encephalomyelitis Virus Model of Epilepsy
  Epilepsia Open. 03, 2022  |   Pubmed ID: 34668659
• Development of an Antiseizure Drug Screening Platform for Dravet Syndrome at the NINDS Contract Site for the Epilepsy Therapy Screening Program
  Epilepsia. 07, 2021  |   Pubmed ID: 34002394
• Response: Usefulness of the Post-kainate Spontaneous Recurrent Seizure Model for Screening for Antiseizure and for Neuroprotective Effects
  Epilepsia. 05, 2021  |   Pubmed ID: 33778946
• Cannabidiolic Acid Exhibits Entourage-like Improvements of Anticonvulsant Activity in an Acute Rat Model of Seizures
  Epilepsy Research. 01, 2021  |   Pubmed ID: 33310415
• Preventing Neuronal Edema Increases Network Excitability After Traumatic Brain Injury
  The Journal of Clinical Investigation. 11, 2020  |   Pubmed ID: 33044227
• Accurate Detection of Spontaneous Seizures Using a Generalized Linear Model with External Validation
  Epilepsia. 09, 2020  |   Pubmed ID: 32761902
• Entrapping Bupivacaine-loaded Emulsions in a Crosslinked-hydrogel Increases Anesthetic Effect and Duration in a Rat Sciatic Nerve Block Model
  International Journal of Pharmaceutics. Oct, 2020  |   Pubmed ID: 32739385
• Evaluation of Subchronic Administration of Antiseizure Drugs in Spontaneously Seizing Rats
  Epilepsia. 06, 2020  |   Pubmed ID: 32420627
• Discovery of the First Vitamin K Analogue As a Potential Treatment of Pharmacoresistant Seizures
  Journal of Medicinal Chemistry. 06, 2020  |   Pubmed ID: 32390424
• The Current Approach of the Epilepsy Therapy Screening Program Contract Site for Identifying Improved Therapies for the Treatment of Pharmacoresistant Seizures in Epilepsy
  Neuropharmacology. 04, 2020  |   Pubmed ID: 31790717
• Evaluation of Antiseizure Drug Efficacy and Tolerability in the Rat Lamotrigine-resistant Amygdala Kindling Model
  Epilepsia Open. Sep, 2019  |   Pubmed ID: 31440726
• Music-Enhanced Analgesia and Antiseizure Activities in Animal Models of Pain and Epilepsy: Toward Preclinical Studies Supporting Development of Digital Therapeutics and Their Combinations With Pharmaceutical Drugs
  Frontiers in Neurology. 2019  |   Pubmed ID: 30972009
• Recurrent Epileptiform Discharges in the Medial Entorhinal Cortex of Kainate-treated Rats Are Differentially Sensitive to Antiseizure Drugs
  Epilepsia. 11, 2018  |   Pubmed ID: 30328622
• Potent and Selective Pharmacodynamic Synergy Between the Metabotropic Glutamate Receptor Subtype 2-positive Allosteric Modulator JNJ-46356479 and Levetiracetam in the Mouse 6-Hz (44-mA) Model
  Epilepsia. 03, 2018  |   Pubmed ID: 29360159
• Novel Targets for Developing Antiseizure And, Potentially, Antiepileptogenic Drugs
  Epilepsy Currents. Sep-Oct, 2017  |   Pubmed ID: 29225544
• Evaluation of Cannabidiol in Animal Seizure Models by the Epilepsy Therapy Screening Program (ETSP)
  Neurochemical Research. Jul, 2017  |   Pubmed ID: 28478594
• Development and Pharmacologic Characterization of the Rat 6 Hz Model of Partial Seizures
  Epilepsia. 06, 2017  |   Pubmed ID: 28449218
• Preclinical Analgesic and Safety Evaluation of the GalR2-preferring Analog, NAX 810-2
  Neurochemical Research. Jul, 2017  |   Pubmed ID: 28382595
• Efficacy of MGlu -positive Allosteric Modulators Alone and in Combination with Levetiracetam in the Mouse 6 Hz Model of Psychomotor Seizures
  Epilepsia. 03, 2017  |   Pubmed ID: 28166368
• Preclinical Evaluation of Intravenous NAX 810-2, a Novel GalR2-preferring Analog, for Anticonvulsant Efficacy and Pharmacokinetics
  Epilepsia. 02, 2017  |   Pubmed ID: 28098336
• Analgesic Properties of a Peripherally Acting and GalR2 Receptor-preferring Galanin Analog in Inflammatory, Neuropathic, and Acute Pain Models
  The Journal of Pharmacology and Experimental Therapeutics. Jan, 2015  |   Pubmed ID: 25347995
• Incorporation of Monodisperse Oligoethyleneglycol Amino Acids into Anticonvulsant Analogues of Galanin and Neuropeptide Y Provides Peripherally Acting Analgesics
  Molecular Pharmaceutics. Feb, 2013  |   Pubmed ID: 23259957
• Autonomic and Cellular Mechanisms Mediating Detrimental Cardiac Effects of Status Epilepticus
  Epilepsy Research. Sep, 2010  |   Pubmed ID: 20650612
• Status Epilepticus Induces Cardiac Myofilament Damage and Increased Susceptibility to Arrhythmias in Rats
  American Journal of Physiology. Heart and Circulatory Physiology. Dec, 2009  |   Pubmed ID: 19820194
• Status Epilepticus Produces Chronic Alterations in Cardiac Sympathovagal Balance
  Epilepsia. Apr, 2009  |   Pubmed ID: 18727681
• Differential Regional Effects of Methamphetamine on Dopamine Transport
  European Journal of Pharmacology. Aug, 2008  |   Pubmed ID: 18599036
• Increased Dietary Sodium Alters Fos Expression in the Lamina Terminalis During Intravenous Angiotensin II Infusion
  Experimental Neurology. Mar, 2007  |   Pubmed ID: 17214984
• Increased Dietary Sodium Enhances Activation of Neurons in the Medullary Cardiovascular Pathway During Acute Sodium Loading in the Rat
  Autonomic Neuroscience : Basic & Clinical. Jan, 2005  |   Pubmed ID: 15620568