Catherine Bowes Rickman Department of Ophthalmology Duke University Biography Publications Institution JoVE Articles Catherine Bowes Rickman has not added a biography. If you are Catherine Bowes Rickman and would like to personalize this page please email our Author Liaison for assistance. Publications Distinct Phenotypic Consequences of Pathogenic Mutants Associated with Late-Onset Retinal Degeneration The American Journal of Pathology. Oct, 2022 | Pubmed ID: 36328299 Cell Culture Models to Study Retinal Pigment Epithelium-related Pathogenesis in Age-related Macular Degeneration Experimental Eye Research. Sep, 2022 | Pubmed ID: 35835183 Encapsulating Cas9 into Extracellular Vesicles by Protein Myristoylation Journal of Extracellular Vesicles. Apr, 2022 | Pubmed ID: 35384352 Targeting Lipid Metabolism for the Treatment of Age-Related Macular Degeneration: Insights from Preclinical Mouse Models Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics. Month, 2022 | Pubmed ID: 34788573 High-density Lipoproteins Are a Potential Therapeutic Target for Age-related Macular Degeneration The Journal of Biological Chemistry. Sep, 2020 | Pubmed ID: 32737203 Correction To: Retinal Degenerative Diseases Advances in Experimental Medicine and Biology. Month, 2019 | Pubmed ID: 32274704 Isolation of Retinal Exosome Biomarkers from Blood By Targeted Immunocapture Advances in Experimental Medicine and Biology. Month, 2019 | Pubmed ID: 31884583 Four-Dimensional Microscope-Integrated Optical Coherence Tomography Guidance in a Model Eye Subretinal Surgery Retina (Philadelphia, Pa.). Oct, 2019 | Pubmed ID: 31090685 Microglial Function Is Distinct in Different Anatomical Locations During Retinal Homeostasis and Degeneration Immunity. Mar, 2019 | Pubmed ID: 30850344 Human Complement Factor H Y402H Polymorphism Causes an Age-related Macular Degeneration Phenotype and Lipoprotein Dysregulation in Mice Proceedings of the National Academy of Sciences of the United States of America. Feb, 2019 | Pubmed ID: 30808757 Author Correction: Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers Scientific Reports. Nov, 2018 | Pubmed ID: 30455433 Polarized Exosome Release from the Retinal Pigmented Epithelium Advances in Experimental Medicine and Biology. Month, 2018 | Pubmed ID: 29721985 Effect of Anti-C5a Therapy in a Murine Model of Early/Intermediate Dry Age-Related Macular Degeneration Investigative Ophthalmology & Visual Science. Feb, 2018 | Pubmed ID: 29392311 Complement Factor H in AMD: Bridging Genetic Associations and Pathobiology Progress in Retinal and Eye Research. Jan, 2018 | Pubmed ID: 28928087 Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers Scientific Reports. Jul, 2017 | Pubmed ID: 28687758 Roles of Exosomes in the Normal and Diseased Eye Progress in Retinal and Eye Research. Jul, 2017 | Pubmed ID: 28465248 Oxidative Stress-mediated NFκB Phosphorylation Upregulates P62/SQSTM1 and Promotes Retinal Pigmented Epithelial Cell Survival Through Increased Autophagy PloS One. Month, 2017 | Pubmed ID: 28222108 Lack of the P2X Receptor Protects Against AMD-like Defects and Microparticle Accumulation in a Chronic Oxidative Stress-induced Mouse Model of AMD Biochemical and Biophysical Research Communications. Jan, 2017 | Pubmed ID: 27810364 AMD and the Alternative Complement Pathway: Genetics and Functional Implications Human Genomics. Jun, 2016 | Pubmed ID: 27329102 A Non-Canonical Role for β-Secretase in the Retina Advances in Experimental Medicine and Biology. Month, 2016 | Pubmed ID: 26427429 Regulation of Age-related Macular Degeneration-like Pathology by Complement Factor H Proceedings of the National Academy of Sciences of the United States of America. Jun, 2015 | Pubmed ID: 25991857 Expression of Human Complement Factor H Prevents Age-related Macular Degeneration-like Retina Damage and Kidney Abnormalities in Aged Cfh Knockout Mice The American Journal of Pathology. Jan, 2015 | Pubmed ID: 25447048 Dysregulated Autophagy in the RPE is Associated with Increased Susceptibility to Oxidative Stress and AMD Autophagy. Month, 2014 | Pubmed ID: 25484094 The Role of Complement Dysregulation in AMD Mouse Models Advances in Experimental Medicine and Biology. Month, 2014 | Pubmed ID: 24664701 Dry Age-related Macular Degeneration: Mechanisms, Therapeutic Targets, and Imaging Investigative Ophthalmology & Visual Science. Dec, 2013 | Pubmed ID: 24335072 β-Secretase (BACE1) Inhibition Causes Retinal Pathology by Vascular Dysregulation and Accumulation of Age Pigment EMBO Molecular Medicine. Sep, 2012 | Pubmed ID: 22903875 Automatic Segmentation of Closed-contour Features in Ophthalmic Images Using Graph Theory and Dynamic Programming Biomedical Optics Express. May, 2012 | Pubmed ID: 22567602 ApoER2 Function in the Establishment and Maintenance of Retinal Synaptic Connectivity The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Oct, 2011 | Pubmed ID: 21976526 Anti-amyloid Therapy Protects Against Retinal Pigmented Epithelium Damage and Vision Loss in a Model of Age-related Macular Degeneration Proceedings of the National Academy of Sciences of the United States of America. Jul, 2011 | Pubmed ID: 21690377 Serial Analysis of Gene Expression (SAGE) in Normal Human Trabecular Meshwork Molecular Vision. Apr, 2011 | Pubmed ID: 21528004 Heparan Sulfate, Including That in Bruch's Membrane, Inhibits the Complement Alternative Pathway: Implications for Age-related Macular Degeneration Journal of Immunology (Baltimore, Md. : 1950). Nov, 2010 | Pubmed ID: 20876352 The Pivotal Role of the Complement System in Aging and Age-related Macular Degeneration: Hypothesis Re-visited Progress in Retinal and Eye Research. Mar, 2010 | Pubmed ID: 19961953 Developing SDOCT to Assess Donor Human Eyes Prior to Tissue Sectioning for Research Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Fur Klinische Und Experimentelle Ophthalmologie. Aug, 2009 | Pubmed ID: 19225801 Evaluation of the X-linked High-grade Myopia Locus (MYP1) with Cone Dysfunction and Color Vision Deficiencies Investigative Ophthalmology & Visual Science. Apr, 2009 | Pubmed ID: 19098318 Rapid and Sensitive Method for Detection of Y402, H402, I62, and V62 Variants of Complement Factor H in Human Plasma Samples Using Mass Spectrometry Investigative Ophthalmology & Visual Science. Apr, 2009 | Pubmed ID: 19029036 NEIBank: Genomics and Bioinformatics Resources for Vision Research Molecular Vision. Jul, 2008 | Pubmed ID: 18648525 Recurrent Choroidal Neovascularization After Macular Translocation Surgery with 360-degree Peripheral Retinectomy Retina (Philadelphia, Pa.). Oct, 2008 | Pubmed ID: 18626416 ERG Responses and Microarray Analysis of Gene Expression in a Multifactorial Murine Model of Age-related Retinal Degeneration Advances in Experimental Medicine and Biology. Month, 2008 | Pubmed ID: 18188941 Targeting Age-related Macular Degeneration with Alzheimer's Disease Based Immunotherapies: Anti-amyloid-beta Antibody Attenuates Pathologies in an Age-related Macular Degeneration Mouse Model Vision Research. Feb, 2008 | Pubmed ID: 17888483 Oxidative Stress-induced Expression and Modulation of Phosphatase of Regenerating Liver-1 (PRL-1) in Mammalian Retina Biochimica Et Biophysica Acta. Sep, 2007 | Pubmed ID: 17673310 Initial Observations of Key Features of Age-related Macular Degeneration in APOE Targeted Replacement Mice Advances in Experimental Medicine and Biology. Month, 2006 | Pubmed ID: 17249563 Why Do Mutations in the Ubiquitously Expressed Housekeeping Gene IMPDH1 Cause Retina-specific Photoreceptor Degeneration? Investigative Ophthalmology & Visual Science. Sep, 2006 | Pubmed ID: 16936083 Defining the Human Macula Transcriptome and Candidate Retinal Disease Genes Using EyeSAGE Investigative Ophthalmology & Visual Science. Jun, 2006 | Pubmed ID: 16723438 Recurrence of Retinal Pigment Epithelial Changes After Macular Translocation with 360 Degrees Peripheral Retinectomy for Geographic Atrophy Archives of Ophthalmology (Chicago, Ill. : 1960). Jul, 2005 | Pubmed ID: 16009834 Human RPE Expression of Cell Survival Factors Investigative Ophthalmology & Visual Science. May, 2005 | Pubmed ID: 15851579 Unraveling a Multifactorial Late-onset Disease: from Genetic Susceptibility to Disease Mechanisms for Age-related Macular Degeneration Annual Review of Genomics and Human Genetics. Month, | Pubmed ID: 19405847 A Protocol to Evaluate and Quantify Retinal Pigmented Epithelium Pathologies in Mouse Models of Age-Related Macular Degeneration Michael Landowski1,2, Samuel Grindel1, Ying Hao3, Sakae Ikeda1,2, Catherine Bowes Rickman3,4, Akihiro Ikeda1,2 1Department of Medical Genetics, University of Wisconsin-Madison, 2McPherson Eye Research Institute, University of Wisconsin-Madison, 3Department of Ophthalmology, Duke University, 4Department of Cell Biology, Duke University JoVE 64927 Genetics
A Protocol to Evaluate and Quantify Retinal Pigmented Epithelium Pathologies in Mouse Models of Age-Related Macular Degeneration Michael Landowski1,2, Samuel Grindel1, Ying Hao3, Sakae Ikeda1,2, Catherine Bowes Rickman3,4, Akihiro Ikeda1,2 1Department of Medical Genetics, University of Wisconsin-Madison, 2McPherson Eye Research Institute, University of Wisconsin-Madison, 3Department of Ophthalmology, Duke University, 4Department of Cell Biology, Duke University JoVE 64927 Genetics
