Charles A. Parkos

Publications

• Dysregulation of Intestinal Epithelial CFTR-dependent Cl Ion Transport and Paracellular Barrier Function Drives Gastrointestinal Symptoms of Food-induced Anaphylaxis in Mice
  Mucosal Immunology. 01, 2021  |   Pubmed ID: 32576925
• WD40 Repeat Protein 26 Negatively Regulates Formyl Peptide Receptor-1 Mediated Wound Healing in Intestinal Epithelial Cells
  The American Journal of Pathology. 10, 2020  |   Pubmed ID: 32958140
• Neutrophil Expressed CD47 Regulates CD11b/CD18-dependent Neutrophil Transepithelial Migration in the Intestine in Vivo
  Mucosal Immunology. Jun, 2020  |   Pubmed ID: 32561828
• Blocking Integrin αβ-mediated CD4 T Cell Recruitment to the Intestine and Liver Protects Mice from Western Diet-induced Non-alcoholic Steatohepatitis
  Journal of Hepatology. Nov, 2020  |   Pubmed ID: 32540177
• Western Diet-induced Increase in Colonic Bile Acids Compromises Epithelial Barrier in Nonalcoholic Steatohepatitis
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. 05, 2020  |   Pubmed ID: 32275114
• Desmocollin-2 Promotes Intestinal Mucosal Repair by Controlling Integrin-dependent Cell Adhesion and Migration
  Molecular Biology of the Cell. 03, 2020  |   Pubmed ID: 31967937
• Regulation of Neutrophil Function by Selective Targeting of Glycan Epitopes Expressed on the Integrin CD11b/CD18
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. 02, 2020  |   Pubmed ID: 31907993
• Innate Immune Cell-epithelial Crosstalk During Wound Repair
  The Journal of Clinical Investigation. 07, 2019  |   Pubmed ID: 31329162
• Gab2 and Gab3 Redundantly Suppress Colitis by Modulating Macrophage and CD8 T-Cell Activation
  Frontiers in Immunology. 2019  |   Pubmed ID: 30936879
• Macrophage-dependent Neutrophil Recruitment is Impaired Under Conditions of Increased Intestinal Permeability in JAM-A-deficient Mice
  Mucosal Immunology. 05, 2019  |   Pubmed ID: 30745566
• Role of JAM-A Tyrosine Phosphorylation in Epithelial Barrier Dysfunction During Intestinal Inflammation
  Molecular Biology of the Cell. 03, 2019  |   Pubmed ID: 30625033
• Analysis of Leukocyte Transepithelial Migration Using an in Vivo Murine Colonic Loop Model
  JCI Insight. 10, 2018  |   Pubmed ID: 30333307
• Estrogen Receptor-Alpha (ESR1) Governs the Lower Female Reproductive Tract Vulnerability to
  Frontiers in Immunology. 2018  |   Pubmed ID: 29881378
• Role of Negative Regulation of Immune Signaling Pathways in Neutrophil Function
  Journal of Leukocyte Biology. Dec, 2017  |   Pubmed ID: 29345376
• Expression of Lewis-a Glycans on Polymorphonuclear Leukocytes Augments Function by Increasing Transmigration
  Journal of Leukocyte Biology. Sep, 2017  |   Pubmed ID: 28600306
• Defects in CD4+ T Cell LFA-1 Integrin-dependent Adhesion and Proliferation Protect Cd47-/- Mice from EAE
  Journal of Leukocyte Biology. 02, 2017  |   Pubmed ID: 27965383
• IL-17A-mediated Neutrophil Recruitment Limits Expansion of Segmented Filamentous Bacteria
  Mucosal Immunology. 05, 2017  |   Pubmed ID: 27624780
• Claudin-based Barrier Differentiation in the Colonic Epithelial Crypt Niche Involves Hopx/Klf4 and Tcf7l2/Hnf4-α Cascades
  Tissue Barriers. Jul-Sep, 2016  |   Pubmed ID: 27583195
• Pathobiology of Neutrophil-epithelial Interactions
  Immunological Reviews. 09, 2016  |   Pubmed ID: 27558330
• Deposition of Microparticles by Neutrophils Onto Inflamed Epithelium: a New Mechanism to Disrupt Epithelial Intercellular Adhesions and Promote Transepithelial Migration
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. 12, 2016  |   Pubmed ID: 27553226
• Inflammation and the Intestinal Barrier: Leukocyte-Epithelial Cell Interactions, Cell Junction Remodeling, and Mucosal Repair
  Gastroenterology. 10, 2016  |   Pubmed ID: 27436072
• Redox Control of Cas Phosphorylation Requires Abl Kinase in Regulation of Intestinal Epithelial Cell Spreading and Migration
  American Journal of Physiology. Gastrointestinal and Liver Physiology. Sep, 2016  |   Pubmed ID: 27418680
• Loss of Junctional Adhesion Molecule A Promotes Severe Steatohepatitis in Mice on a Diet High in Saturated Fat, Fructose, and Cholesterol
  Gastroenterology. 10, 2016  |   Pubmed ID: 27342212
• Neutrophil-Epithelial Interactions: A Double-Edged Sword
  The American Journal of Pathology. 06, 2016  |   Pubmed ID: 27083514
• Targeting of Neutrophil Lewis X Blocks Transepithelial Migration and Increases Phagocytosis and Degranulation
  The American Journal of Pathology. Feb, 2016  |   Pubmed ID: 26687991
• Cutting Edge: IL-36 Receptor Promotes Resolution of Intestinal Damage
  Journal of Immunology (Baltimore, Md. : 1950). Jan, 2016  |   Pubmed ID: 26590314
• Inflammation-induced Desmoglein-2 Ectodomain Shedding Compromises the Mucosal Barrier
  Molecular Biology of the Cell. Sep, 2015  |   Pubmed ID: 26224314
• HNF4α Regulates Claudin-7 Protein Expression During Intestinal Epithelial Differentiation
  The American Journal of Pathology. Aug, 2015  |   Pubmed ID: 26216285
• Annexin A1-containing Extracellular Vesicles and Polymeric Nanoparticles Promote Epithelial Wound Repair
  The Journal of Clinical Investigation. Mar, 2015  |   Pubmed ID: 25664854
• Junctional Adhesion Molecule A Promotes Epithelial Tight Junction Assembly to Augment Lung Barrier Function
  The American Journal of Pathology. Feb, 2015  |   Pubmed ID: 25438062
• Challenges in IBD Research: Update on Progress and Prioritization of the CCFA's Research Agenda
  Inflammatory Bowel Diseases. Mar, 2013  |   Pubmed ID: 23448796
• Targeting Epithelial Expressed Sialyl Lewis Glycans Improves Colonic Mucosal Wound Healing and Protects Against Colitis
  JCI Insight.   |   Pubmed ID: 32427587
• Resolvin E1 is a Pro-repair Molecule That Promotes Intestinal Epithelial Wound Healing
  Proceedings of the National Academy of Sciences of the United States of America.   |   Pubmed ID: 32300016
• Epithelial CD47 is Critical for Mucosal Repair in the Murine Intestine in Vivo
  Nature Communications.   |   Pubmed ID: 31676794
• Formyl Peptide Receptor 2 Regulates Monocyte Recruitment to Promote Intestinal Mucosal Wound Repair
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology.   |   Pubmed ID: 31585047
• TNFα Promotes Mucosal Wound Repair Through Enhanced Platelet Activating Factor Receptor Signaling in the Epithelium
  Mucosal Immunology.   |   Pubmed ID: 30971752
• Intracellular Desmoglein-2 Cleavage Sensitizes Epithelial Cells to Apoptosis in Response to Pro-inflammatory Cytokines
  Cell Death & Disease.   |   Pubmed ID: 29523777
• Macrophage-derived IL-10 Mediates Mucosal Repair by Epithelial WISP-1 Signaling
  The Journal of Clinical Investigation.   |   Pubmed ID: 28783045