Charles L. Howe

Publications

• The STAT3 Beacon: IL-6 Recurrently Activates STAT 3 from Endosomal Structures
  Experimental Cell Research. Aug, 2011  |   Pubmed ID: 21619877
• Therapeutic Doses of Cranial Irradiation Induce Hippocampus-dependent Cognitive Deficits in Young Mice
  Journal of Neuro-oncology. Nov, 2011  |   Pubmed ID: 21499912
• CD8+ T Cells Cause Disability and Axon Loss in a Mouse Model of Multiple Sclerosis
  PloS One. 2010  |   Pubmed ID: 20814579
• Retraction: TREM-2 Mediated Signaling Induces Antigen Uptake and Retention in Mature Myeloid Dendritic Cells
  Journal of Immunology (Baltimore, Md. : 1950). Jun, 2010  |   Pubmed ID: 20483797
• Inflammatory Changes in the Central Nervous System Are Associated with Behavioral Impairment in Plasmodium Berghei (strain ANKA)-infected Mice
  Experimental Parasitology. Jul, 2010  |   Pubmed ID: 20138873
• Subcutaneous IGF-1 is Not Beneficial in 2-year ALS Trial
  Neurology. Oct, 2009  |   Pubmed ID: 19822878
• Demyelinated Axons and Motor Function Are Protected by Genetic Deletion of Perforin in a Mouse Model of Multiple Sclerosis
  Journal of Neuropathology and Experimental Neurology. Sep, 2009  |   Pubmed ID: 19680139
• Preparation of Biologically Active Subcellular Fractions Using the Balch Homogenizer
  Analytical Biochemistry. Nov, 2009  |   Pubmed ID: 19622341
• Apoptosis of Hippocampal Pyramidal Neurons is Virus Independent in a Mouse Model of Acute Neurovirulent Picornavirus Infection
  The American Journal of Pathology. Aug, 2009  |   Pubmed ID: 19608874
• Functional Characterization of Mouse Spinal Cord Infiltrating CD8+ Lymphocytes
  Journal of Neuroimmunology. Sep, 2009  |   Pubmed ID: 19596449
• TREM-2 Mediated Signaling Induces Antigen Uptake and Retention in Mature Myeloid Dendritic Cells
  Journal of Immunology (Baltimore, Md. : 1950). Dec, 2008  |   Pubmed ID: 19017976
• Aquaporin-4-binding Autoantibodies in Patients with Neuromyelitis Optica Impair Glutamate Transport by Down-regulating EAAT2
  The Journal of Experimental Medicine. Oct, 2008  |   Pubmed ID: 18838545
• NKG2D Contributes to Efficient Clearance of Picornavirus from the Acutely Infected Murine Brain
  Journal of Neurovirology. May, 2008  |   Pubmed ID: 18569460
• Human HLA-DR Transgenes Protect Mice from Fatal Virus-induced Encephalomyelitis and Chronic Demyelination
  Journal of Virology. Apr, 2008  |   Pubmed ID: 18234804
• TRAIL Mediates Liver Injury by the Innate Immune System in the Bile Duct-ligated Mouse
  Hepatology (Baltimore, Md.). Apr, 2008  |   Pubmed ID: 18220275
• A Randomized Phase I Study of Atuna Racemosa: a Potential New Anti-MRSA Natural Product Extract
  Journal of Ethnopharmacology. Dec, 2007  |   Pubmed ID: 17889468
• CD8+ T Cells Directed Against a Viral Peptide Contribute to Loss of Motor Function by Disrupting Axonal Transport in a Viral Model of Fulminant Demyelination
  Journal of Neuroimmunology. Aug, 2007  |   Pubmed ID: 17493690
• Beta-methylamino-alanine (BMAA) Injures Hippocampal Neurons in Vivo
  Neurotoxicology. May, 2007  |   Pubmed ID: 17379313
• Mechanisms of Action of IVIG in Adult Onset Rasmussen's Encephalitis
  The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques. Feb, 2007  |   Pubmed ID: 17352358
• A High-throughput 3-parameter Flow Cytometry-based Cell Death Assay
  Cytometry. Part A : the Journal of the International Society for Analytical Cytology. Mar, 2007  |   Pubmed ID: 17226860
• Absence of Perforin Expression Confers Axonal Protection Despite Demyelination
  Neurobiology of Disease. Feb, 2007  |   Pubmed ID: 17112732
• Searching Historical Herbal Texts for Potential New Drugs
  BMJ (Clinical Research Ed.). Dec, 2006  |   Pubmed ID: 17185721
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  Cells, Tissues, Organs. 2006  |   Pubmed ID: 17159344
• Induction of a Gene Expression Program in Dendritic Cells with a Cross-linking IgM Antibody to the Co-stimulatory Molecule B7-DC
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Nov, 2006  |   Pubmed ID: 17023390
• Disrupted Spatial Memory is a Consequence of Picornavirus Infection
  Neurobiology of Disease. Nov, 2006  |   Pubmed ID: 16919964
• Activated Microglia Stimulate Transcriptional Changes in Primary Oligodendrocytes Via IL-1beta
  Neurobiology of Disease. Sep, 2006  |   Pubmed ID: 16887357
• Picornaviruses and Cell Death
  Trends in Microbiology. Jan, 2006  |   Pubmed ID: 16337385
• Modeling the Signaling Endosome Hypothesis: Why a Drive to the Nucleus is Better Than a (random) Walk
  Theoretical Biology & Medical Modelling. 2005  |   Pubmed ID: 16236165
• Differential Endocytic Sorting of P75NTR and TrkA in Response to NGF: a Role for Late Endosomes in TrkA Trafficking
  Molecular and Cellular Neurosciences. Mar, 2005  |   Pubmed ID: 15737746
• Long-distance Retrograde Neurotrophic Signaling
  Current Opinion in Neurobiology. Feb, 2005  |   Pubmed ID: 15721743
• Differences in the Surface Binding and Endocytosis of Neurotrophins by P75NTR
  Molecular and Cellular Neurosciences. Jun, 2004  |   Pubmed ID: 15207854
• Antiapoptotic Signaling by a Remyelination-promoting Human Antimyelin Antibody
  Neurobiology of Disease. Feb, 2004  |   Pubmed ID: 14751777
• Signaling Endosome Hypothesis: A Cellular Mechanism for Long Distance Communication
  Journal of Neurobiology. Feb, 2004  |   Pubmed ID: 14704953
• Trafficking the NGF Signal: Implications for Normal and Degenerating Neurons
  Progress in Brain Research. 2004  |   Pubmed ID: 14699953
• Human Monoclonal IgM Antibody Promotes CNS Myelin Repair Independent of Fc Function
  Brain Pathology (Zurich, Switzerland). Oct, 2003  |   Pubmed ID: 14655764
• Gamma Interferon is Critical for Neuronal Viral Clearance and Protection in a Susceptible Mouse Strain Following Early Intracranial Theiler's Murine Encephalomyelitis Virus Infection
  Journal of Virology. Nov, 2003  |   Pubmed ID: 14581562
• Depolarization of PC12 Cells Induces Neurite Outgrowth and Enhances Nerve Growth Factor-induced Neurite Outgrowth in Rats
  Neuroscience Letters. Nov, 2003  |   Pubmed ID: 14550909
• Interleukin-6 Protects Anterior Horn Neurons from Lethal Virus-induced Injury
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jan, 2003  |   Pubmed ID: 12533608
• Growth Factor Treatment of Demyelinating Disease: at Last, a Leap into the Light
  Trends in Immunology. Nov, 2002  |   Pubmed ID: 12401395