In JoVE (1)
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Articles by Cheng-Han Yang in JoVE
The Establishment of a Lung Colonization Assay for Circulating Tumor Cell Visualization in Lung Tissues Tsung-Cheng Lin1, Ying-Chih Liao2, Wen-Tsan Chang1,2, Cheng-Han Yang1, Li-Hsin Cheng1, Megan Cheng3, Hung-Chi Cheng1,2 1The Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, 2Department of Biochemistry and Molecular Biology, College of Medicine, National Cheng Kung University, 3 An animal model is needed to decipher the role of circulating tumor cells (CTCs) in promoting lung colonization during cancer metastasis. Here, we established and successfully performed an in vivo assay to specifically test the requirement of polymeric fibronectin (polyFN) assembly on CTCs for lung colonization.